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Understanding transport through pharmacological barriers--are we there yet?
- Published in:
- 2010
- By:
- Publication type:
- letter
Targeting multidrug resistance in cancer.
- Published in:
- 2006
- By:
- Publication type:
- journal article
Active transport of rhodamine 123 by the human multidrug transporter P-glycoprotein involves two independent outer gates.
- Published in:
- Pharmacology Research & Perspectives, 2020, v. 8, n. 2, p. 1, doi. 10.1002/prp2.572
- By:
- Publication type:
- Article
Generation of a Homozygous Transgenic Rat Strain Stably Expressing a Calcium Sensor Protein for Direct Examination of Calcium Signaling.
- Published in:
- Scientific Reports, 2015, p. 12645, doi. 10.1038/srep12645
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- Publication type:
- Article
Comparison of Different Clinical Chemotherapeutical Agents' Toxicity and Cell Response on Mesenchymal Stem Cells and Cancer Cells.
- Published in:
- Cells (2073-4409), 2022, v. 11, n. 19, p. 2942, doi. 10.3390/cells11192942
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- Publication type:
- Article
ABCC1 and glutathione metabolism limit the efficacy of BCL-2 inhibitors in acute myeloid leukemia.
- Published in:
- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-41229-2
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- Publication type:
- Article
The thiosemicarbazone Me<sub>2</sub>NNMe<sub>2</sub> induces paraptosis by disrupting the ER thiol redox homeostasis based on protein disulfide isomerase inhibition.
- Published in:
- Cell Death & Disease, 2018, v. 9, n. 11, p. 1, doi. 10.1038/s41419-018-1102-z
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- Publication type:
- Article
Expression pattern of the human ABC transporters in pluripotent embryonic stem cells and in their derivatives.
- Published in:
- Cytometry. Part B, 2014, v. 86, n. 5, p. 299, doi. 10.1002/cyto.b.21168
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- Publication type:
- Article
Characterization of new, efficient Mycobacterium tuberculosis topoisomerase-I inhibitors and their interaction with human ABC multidrug transporters.
- Published in:
- PLoS ONE, 2018, v. 13, n. 9, p. 1, doi. 10.1371/journal.pone.0202749
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- Publication type:
- Article
A new fluorescent dye accumulation assay for parallel measurements of the ABCG2, ABCB1 and ABCC1 multidrug transporter functions.
- Published in:
- PLoS ONE, 2018, v. 13, n. 1, p. 1, doi. 10.1371/journal.pone.0190629
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- Publication type:
- Article
DNA‐dependent phase separation by human SSB2 (NABP1/OBFC2A) protein points to adaptations to eukaryotic genome repair processes.
- Published in:
- Protein Science: A Publication of the Protein Society, 2024, v. 33, n. 4, p. 1, doi. 10.1002/pro.4959
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- Publication type:
- Article
Efficient Synthesis of Acylated, Dialkyl α-Hydroxy-Benzylphosphonates and Their Anticancer Activity.
- Published in:
- Molecules, 2022, v. 27, n. 7, p. 2067, doi. 10.3390/molecules27072067
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- Publication type:
- Article
Synthesis and Anticancer Cytotoxicity of Azaaurones Overcoming Multidrug Resistance.
- Published in:
- Molecules, 2020, v. 25, n. 3, p. 764, doi. 10.3390/molecules25030764
- By:
- Publication type:
- Article
Correlation of homologous recombination deficiency induced mutational signatures with sensitivity to PARP inhibitors and cytotoxic agents.
- Published in:
- Genome Biology, 2019, v. 20, n. 1, p. 1, doi. 10.1186/s13059-019-1867-0
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- Publication type:
- Article
Metal Complexes of a 5-Nitro-8-Hydroxyquinoline-Proline Hybrid with Enhanced Water Solubility Targeting Multidrug Resistant Cancer Cells.
- Published in:
- International Journal of Molecular Sciences, 2023, v. 24, n. 1, p. 593, doi. 10.3390/ijms24010593
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- Publication type:
- Article
Establishment and Characterization of a Brca1−/−, p53−/− Mouse Mammary Tumor Cell Line.
- Published in:
- International Journal of Molecular Sciences, 2020, v. 21, n. 4, p. 1185, doi. 10.3390/ijms21041185
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- Publication type:
- Article
Characterisation of Canine and Feline Breast Tumours, Their Metastases, and Corresponding Primary Cell Lines Using LA-REIMS and DESI-MS Imaging.
- Published in:
- International Journal of Molecular Sciences, 2024, v. 25, n. 14, p. 7752, doi. 10.3390/ijms25147752
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- Publication type:
- Article
Mesenchymal Stem Cells Increase Drug Tolerance of A431 Cells Only in 3D Spheroids, Not in 2D Co-Cultures.
- Published in:
- International Journal of Molecular Sciences, 2024, v. 25, n. 8, p. 4515, doi. 10.3390/ijms25084515
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- Publication type:
- Article
Expression of calcium pumps is differentially regulated by histone deacetylase inhibitors and estrogen receptor alpha in breast cancer cells.
- Published in:
- 2018
- By:
- Publication type:
- journal article
Calcein assay for multidrug resistance reliably predicts therapy response and survival rate in acute myeloid leukaemia.
- Published in:
- British Journal of Haematology, 2001, v. 112, n. 2, p. 308, doi. 10.1046/j.1365-2141.2001.02554.x
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- Publication type:
- Article
Expression Levels of the ABCG2 Multidrug Transporter in Human Erythrocytes Correspond to Pharmacologically Relevant Genetic Variations.
- Published in:
- PLoS ONE, 2012, v. 7, n. 11, p. 1, doi. 10.1371/journal.pone.0048423
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- Publication type:
- Article
Evaluation of ABCG2 Expression in Human Embryonic Stem Cells: Crossing the Same River Twice?
- Published in:
- 2010
- By:
- Publication type:
- Letter
Identification of anticancer OATP2B1 substrates by an in vitro triple-fluorescence-based cytotoxicity screen.
- Published in:
- Archives of Toxicology, 2019, v. 93, n. 4, p. 953, doi. 10.1007/s00204-019-02417-6
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- Publication type:
- Article
Identification of Extracellular Segments by Mass Spectrometry Improves Topology Prediction of Transmembrane Proteins.
- Published in:
- Scientific Reports, 2017, p. 42610, doi. 10.1038/srep42610
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- Publication type:
- Article
A single active catalytic site is sufficient to promote transport in P-glycoprotein.
- Published in:
- Scientific Reports, 2016, p. 24810, doi. 10.1038/srep24810
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- Publication type:
- Article
Synthesis and SAR Study of Anticancer Protoflavone Derivatives: Investigation of Cytotoxicity and Interaction with ABCB1 and ABCG2 Multidrug Efflux Transporters.
- Published in:
- ChemMedChem, 2017, v. 12, n. 11, p. 850, doi. 10.1002/cmdc.201700225
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- Publication type:
- Article
The human ABCB6 protein is the functional homologue of HMT-1 proteins mediating cadmium detoxification.
- Published in:
- Cellular & Molecular Life Sciences, 2019, v. 76, n. 20, p. 4131, doi. 10.1007/s00018-019-03105-5
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- Publication type:
- Article
Experimental Closed-Loop Control of Breast Cancer in Mice.
- Published in:
- Complexity, 2022, p. 1, doi. 10.1155/2022/9348166
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- Publication type:
- Article
Identifying new topoisomerase II poison scaffolds by combining publicly available toxicity data and 2D/3D-based virtual screening.
- Published in:
- Journal of Cheminformatics, 2019, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13321-019-0390-3
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- Publication type:
- Article
NGR-peptide−drug conjugates with dual targeting properties.
- Published in:
- PLoS ONE, 2017, v. 12, n. 6, p. 1, doi. 10.1371/journal.pone.0178632
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- Publication type:
- Article
Human ABCB1 with an ABCB11-like degenerate nucleotide binding site maintains transport activity by avoiding nucleotide occlusion.
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- PLoS Genetics, 2020, v. 16, n. 10, p. 1, doi. 10.1371/journal.pgen.1009016
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- Publication type:
- Article
A novel cyclic RGD-containing peptide polymer improves serum-free adhesion of adipose tissue-derived mesenchymal stem cells to bone implant surfaces.
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- Journal of Materials Science: Materials in Medicine, 2013, v. 24, n. 2, p. 479, doi. 10.1007/s10856-012-4809-x
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- Publication type:
- Article
In vivo characterization of [18F]AVT-011 as a radiotracer for PET imaging of multidrug resistance.
- Published in:
- European Journal of Nuclear Medicine & Molecular Imaging, 2020, v. 47, n. 8, p. 2026, doi. 10.1007/s00259-019-04589-w
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- Publication type:
- Article
P-Glycoprotein Activity at Diagnosis Does Not Predict Therapy Outcome and Survival in Canine B-Cell Lymphoma.
- Published in:
- Cancers, 2022, v. 14, n. 16, p. 3919, doi. 10.3390/cancers14163919
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- Publication type:
- Article
Mesenchymal-Stromal Cell-like Melanoma-Associated Fibroblasts Increase IL-10 Production by Macrophages in a Cyclooxygenase/Indoleamine 2,3-Dioxygenase-Dependent Manner.
- Published in:
- Cancers, 2021, v. 13, n. 24, p. 6173, doi. 10.3390/cancers13246173
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- Publication type:
- Article
Relation of Metal-Binding Property and Selective Toxicity of 8-Hydroxyquinoline Derived Mannich Bases Targeting Multidrug Resistant Cancer Cells.
- Published in:
- Cancers, 2021, v. 13, n. 1, p. 154, doi. 10.3390/cancers13010154
- By:
- Publication type:
- Article
Celecoxib Prevents Doxorubicin-Induced Multidrug Resistance in Canine and Mouse Lymphoma Cell Lines.
- Published in:
- Cancers, 2020, v. 12, n. 5, p. 1117, doi. 10.3390/cancers12051117
- By:
- Publication type:
- Article
Influence of OATPs on Hepatic Disposition of Erlotinib Measured With Positron Emission Tomography.
- Published in:
- Clinical Pharmacology & Therapeutics, 2018, v. 104, n. 1, p. 139, doi. 10.1002/cpt.888
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- Publication type:
- Article
Diagnostics of multidrug resistance in cancer.
- Published in:
- Pathology & Oncology Research, 1998, v. 4, n. 4, p. 251, doi. 10.1007/BF02905214
- By:
- Publication type:
- Article
Development and In Vivo Application of a Water-Soluble Anticancer Copper Ionophore System Using a Temperature-Sensitive Liposome Formulation.
- Published in:
- Pharmaceutics, 2020, v. 12, n. 5, p. 466, doi. 10.3390/pharmaceutics12050466
- By:
- Publication type:
- Article
Characterization of Disease-Associated Mutations in Human Transmembrane Proteins.
- Published in:
- PLoS ONE, 2016, v. 11, n. 3, p. 1, doi. 10.1371/journal.pone.0151760
- By:
- Publication type:
- Article
A Novel Mathematical Model Describing Adaptive Cellular Drug Metabolism and Toxicity in the Chemoimmune System.
- Published in:
- PLoS ONE, 2015, v. 10, n. 2, p. 1, doi. 10.1371/journal.pone.0115533
- By:
- Publication type:
- Article
A mass spectrometry based functional assay for the quantitative assessment of ABC transporter activity.
- Published in:
- Rapid Communications in Mass Spectrometry: RCM, 2009, v. 23, n. 21, p. 3372, doi. 10.1002/rcm.4259
- By:
- Publication type:
- Article
A novel fluorescence‐based functional assay for human OATP1A2 and OATP1C1 identifies interaction between third‐generation P‐gp inhibitors and OATP1A2.
- Published in:
- FEBS Journal, 2020, v. 287, n. 12, p. 2468, doi. 10.1111/febs.15156
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- Publication type:
- Article