Works by SHEPHERD, Peter R.

Results: 53

Efficacy of Providing the PI3K p110α Inhibitor BYL719 (Alpelisib) to Middle-Aged Mice in Their Diet.
Published in:
Biomolecules (2218-273X), 2021, v. 11, n. 2, p. 150, doi. 10.3390/biom11020150
By:
- Hedges, Christopher P.;
- Boix, Jordi;
- Jaiswal, Jagdish K.;
- Shetty, Bhoopika;
- Shepherd, Peter R.;
- Merry, Troy L.
Publication type:
Article
For Better or Worse: The Potential for Dose Limiting the On-Target Toxicity of PI 3-Kinase Inhibitors.
Published in:
Biomolecules (2218-273X), 2019, v. 9, n. 9, p. 402, doi. 10.3390/biom9090402
By:
- Buchanan, Christina M.;
- Lee, Kate L.;
- Shepherd, Peter R.
Publication type:
Article
Glucagon phosphorylates serine 552 of β-catenin leading to increased expression of cyclin D1 and c-Myc in the isolated rat liver.
Published in:
Archives of Physiology & Biochemistry, 2015, v. 121, n. 3, p. 88, doi. 10.3109/13813455.2015.1048693
By:
- Chowdhury, Md. Kamrul H.;
- Montgomery, Magda K.;
- Morris, Margaret J.;
- Cognard, Emmanuelle;
- Shepherd, Peter R.;
- Smith, Greg C.
Publication type:
Article
Stratified glucose-lowering response to vildagliptin and pioglitazone by obesity and hypertriglyceridemia in a randomized crossover trial.
Published in:
Frontiers in Endocrinology, 2023, v. 13, p. 1, doi. 10.3389/fendo.2022.1091421
By:
- Brandon, Rebecca;
- Yannan Jiang;
- Rui Qian Yeu;
- Tweedie-Cullen, Ry;
- Smallman, Kate;
- Doherty, Glenn;
- Macaskill-Smith, Kerry A.;
- Doran, Rebekah J.;
- Clark, Penny;
- Moffitt, Allan;
- Merry, Troy;
- Nehren, Norma;
- King, Frances;
- Hindmarsh, Jennie Harré;
- Leask, Megan Patricia;
- Merriman, Tony R.;
- Orr-Walker, Brandon;
- Shepherd, Peter R.;
- Paul, Ryan;
- Murphy, Rinki
Publication type:
Article
Genomic and signalling pathway characterization of the NZM panel of melanoma cell lines: A valuable model for studying the impact of genetic diversity in melanoma.
Published in:
Pigment Cell & Melanoma Research, 2021, v. 34, n. 1, p. 136, doi. 10.1111/pcmr.12908
By:
- Tran, Khanh B.;
- Gimenez, Gregory;
- Tsai, Peter;
- Kolekar, Sharada;
- Rodger, Euan J.;
- Chatterjee, Aniruddha;
- Jabed, Anower;
- Shih, Jen‐Hsing;
- Joseph, Wayne R.;
- Marshall, Elaine S.;
- Wang, Qian;
- Print, Cristin G.;
- Eccles, Michael R.;
- Baguley, Bruce C.;
- Shepherd, Peter R.
Publication type:
Article
Phosphorylation of glycosyl-phosphatidylinositol by phosphatidylinositol 3-kinase changes its properties as a substrate for phospholipases
Published in:
FEBS Letters, 2005, v. 579, n. 1, p. 59, doi. 10.1016/j.febslet.2004.11.035
By:
- Jones, David R.;
- Pañeda, Covadonga;
- Villar, Ana Victoria;
- Alonso, Alicia;
- Goñi, Félix M.;
- Bütikofer, Peter;
- Brodbeck, Urs;
- Shepherd, Peter R.;
- Varela-Nieto, Isabel
Publication type:
Article
ATP-competitive inhibitors of PI3K enzymes demonstrate an isoform selective dual action by controlling membrane binding.
Published in:
Biochemical Journal, 2024, v. 481, n. 23, p. 1787, doi. 10.1042/BCJ20240479
By:
- Gong, Grace Q.;
- Masson, Glenn R.;
- Woo-Jeong Lee;
- Dickson, James M. J.;
- Kendall, Jackie D.;
- Rathinaswamy, Manoj K.;
- Buchanan, Christina M.;
- Middleditch, Martin;
- Owen, Brady M.;
- Spicer, Julie A.;
- Rewcastle, Gordon W.;
- Denny, William A.;
- Burke, John E.;
- Shepherd, Peter R.;
- Williams, Roger L.;
- Flanagan, Jack U.
Publication type:
Article
A role for PAK1 mediated phosphorylation of β-catenin Ser552 in the regulation of insulin secretion.
Published in:
Biochemical Journal, 2021, v. 478, n. 8, p. 1605, doi. 10.1042/BCJ20200862
By:
- Sorrenson, Brie;
- Dissanayake, Waruni C.;
- Fengyun Hu;
- Lee, Kate L.;
- Shepherd, Peter R.
Publication type:
Article
α-catenin isoforms are regulated by glucose and involved in regulating insulin secretion in rat clonal β-cell models.
Published in:
Biochemical Journal, 2020, v. 477, n. 4, p. 763, doi. 10.1042/BCJ20190832
By:
- Dissanayake, Waruni C.;
- Sorrenson, Brie;
- Lee, Kate L.;
- Barre, Sandra;
- Shepherd, Peter R.
Publication type:
Article
A role for β‐catenin in diet‐induced skeletal muscle insulin resistance.
Published in:
Physiological Reports, 2023, v. 11, n. 4, p. 1, doi. 10.14814/phy2.15536
By:
- Masson, Stewart W. C.;
- Dissanayake, Waruni C.;
- Broome, Sophie C.;
- Hedges, Christopher P.;
- Peeters, Wouter M.;
- Gram, Martin;
- Rowlands, David S.;
- Shepherd, Peter R.;
- Merry, Troy L.
Publication type:
Article
A Polynesian-specific SLC22A3 variant associates with low plasma lipoprotein(a) concentrations independent of apo(a) isoform size in males.
Published in:
Bioscience Reports, 2024, v. 44, n. 7, p. 1, doi. 10.1042/BSR20240403
By:
- Wang, Qian;
- McCormick, Sally;
- Leask, Megan P.;
- Watson, Huti;
- O'Sullivan, Conor;
- Krebs, Jeremy D.;
- Hall, Rosemary;
- Whitfield, Patricia;
- Merry, Troy L.;
- Murphy, Rinki;
- Shepherd, Peter R.
Publication type:
Article
Evidence that RXFP4 is located in enterochromaffin cells and can regulate production and release of serotonin.
Published in:
Bioscience Reports, 2023, v. 43, n. 4, p. 1, doi. 10.1042/BSR20221956
By:
- Fernando, Shalinda J. A.;
- Qian Wang;
- Hay, Debbie L.;
- Bathgate, Ross A. D.;
- Shepherd, Peter R.;
- Lee, Kate L.
Publication type:
Article
Glucose regulates expression of pro-inflammatory genes, IL-1β and IL-12, through a mechanism involving hexosamine biosynthesis pathway-dependent regulation of α-E catenin.
Published in:
Bioscience Reports, 2021, v. 41, n. 7, p. 1, doi. 10.1042/BSR20211066
By:
- Dissanayake, Waruni C.;
- Oh, Jin Kyo;
- Sorrenson, Brie;
- Shepherd, Peter R.
Publication type:
Article
Prolonged treatment with a PI3K p110a inhibitor causes sex- and tissue-dependent changes in antioxidant content, but does not affect mitochondrial function.
Published in:
Bioscience Reports, 2020, v. 40, n. 10, p. 1, doi. 10.1042/BSR20201128
By:
- Hedges, Christopher P.;
- Pham, Toan;
- Shetty, Bhoopika;
- Masson, Stewart W. C.;
- Hickey, Anthony J. R.;
- Shepherd, Peter R.;
- Merry, Troy L.
Publication type:
Article
The role of adherens junction proteins in the regulation of insulin secretion.
Published in:
Bioscience Reports, 2018, v. 38, n. 2, p. 1, doi. 10.1042/BSR20170989
By:
- Dissanayake, Waruni C.;
- Sorrenson, Brie;
- Shepherd, Peter R.
Publication type:
Article
Enzyme activity effects of N-terminal His-tag attached to catalytic sub-unit of phosphoinositide-3-kinase.
Published in:
Bioscience Reports, 2013, v. 33, n. 6, p. 857, doi. 10.1042/BSR20130075
By:
- DICKSON, James M. J.;
- Woo-Jeong LEE;
- SHEPHERD, Peter R.;
- BUCHANAN, Christina M.
Publication type:
Article
Derivation of induced pluripotent stem cell lines from New Zealand donors.
Published in:
Journal of the Royal Society of New Zealand, 2022, v. 52, n. 1, p. 54, doi. 10.1080/03036758.2020.1830808
By:
- Oh, Jin Kyo;
- Przepiorski, Aneta;
- Chang, Hao-Han;
- Dodd, Rachel C.;
- Sander, Veronika;
- Sorrenson, Brie;
- Shih, Jen-Hsing;
- Hollywood, Jennifer A.;
- de Zoysa, Janak R.;
- Shepherd, Peter R.;
- Davidson, Alan J.;
- Holm, Teresa M.
Publication type:
Article
The phosphoinositide 3′-kinase p110δ modulates contractile protein production and IL-6 release in human airway smooth muscle.
Published in:
Journal of Cellular Physiology, 2012, v. 227, n. 8, p. 3044, doi. 10.1002/jcp.23046
By:
- Ge, Qi;
- Moir, Lyn M.;
- Trian, Thomas;
- Niimi, Kyoko;
- Poniris, Maree;
- Shepherd, Peter R.;
- Black, Judith L.;
- Oliver, Brian G.;
- Burgess, Janette K.
Publication type:
Article
Insights into the role of JAK2-I724T variant in myeloproliferative neoplasms from a unique cohort of New Zealand patients.
Published in:
Hematology, 2024, v. 29, n. 1, p. 1, doi. 10.1080/16078454.2023.2297597
By:
- Puli'uvea, Christopher;
- Immanuel, Tracey;
- Green, Taryn N.;
- Tsai, Peter;
- Shepherd, Peter R.;
- Kalev-Zylinska, Maggie L.
Publication type:
Article
β‐Catenin is required for optimal exercise‐ and contraction‐stimulated skeletal muscle glucose uptake.
Published in:
Journal of Physiology, 2021, v. 599, n. 16, p. 3897, doi. 10.1113/JP281352
By:
- Masson, Stewart W. C.;
- Woodhead, Jonathan S. T.;
- D'Souza, Randall F.;
- Broome, Sophie C.;
- MacRae, Caitlin;
- Cho, Hyun C.;
- Atiola, Robert D.;
- Futi, Tumanu;
- Dent, Jessica R.;
- Shepherd, Peter R.;
- Merry, Troy L.
Publication type:
Article
Limited Metabolic Effect of the CREBRF R457Q Obesity Variant in Mice.
Published in:
Cells (2073-4409), 2022, v. 11, n. 3, p. 497, doi. 10.3390/cells11030497
By:
- Metcalfe, Louise K.;
- Shepherd, Peter R.;
- Smith, Greg C.;
- Turner, Nigel
Publication type:
Article
Synthesis and Evaluation of Imidazo[1,2‐a]pyridine Analogues of the ZSTK474 Class of Phosphatidylinositol 3‐Kinase Inhibitors.
Published in:
Chemistry - An Asian Journal, 2019, v. 14, n. 8, p. 1249, doi. 10.1002/asia.201801762
By:
- Gamage, Swarna A.;
- Spicer, Julie A.;
- Tsang, Kit Y.;
- O'Connor, Patrick D.;
- Flanagan, Jack U.;
- Lee, Woo‐Jeong;
- Dickson, James M. J.;
- Shepherd, Peter R.;
- Denny, William A.;
- Rewcastle, Gordon W.
Publication type:
Article
NVP-BEZ235, A Dual Pan Class I PI3 Kinase and mTOR Inhibitor, Promotes Osteogenic Differentiation in Human Mesenchymal Stromal Cells.
Published in:
Journal of Bone & Mineral Research, 2010, v. 25, n. 10, p. 2126, doi. 10.1002/jbmr.114
By:
- Martin, Sally K.;
- Fitter, Stephen;
- Li Fei Bong;
- Drew, Jennifer J.;
- Gronthos, Stan;
- Shepherd, Peter R.;
- Zannettino, Andrew C. W.
Publication type:
Article
Insulin and leptin acutely regulate cholesterol ester metabolism in macrophages by novel signaling pathways.
Published in:
2001
By:
- O'Rourke, Lisa;
- Yeaman, Steven J.;
- Shepherd, Peter R.;
- O'Rourke, L;
- Yeaman, S J;
- Shepherd, P R
Publication type:
journal article
Human small intestine facilitative fructose/glucose transporter (GLUT5) is also present in insulin-responsive tissues and brain. Investigation of biochemical characteristics and translocation.
Published in:
1992
By:
- Shepherd, Peter R.;
- Gibbs, E. Michael;
- Wesslau, Christian;
- Gould, Gwyn W.;
- Kahn, Barbara B.;
- Shepherd, P R;
- Gibbs, E M;
- Wesslau, C;
- Gould, G W;
- Kahn, B B
Publication type:
journal article
Protein Kinase Activity of Phosphoinositide 3-Kinase Regulates Cytokine-Dependent Cell Survival.
Published in:
PLoS Biology, 2013, v. 11, n. 3, p. 1, doi. 10.1371/journal.pbio.1001515
By:
- Thomas, Daniel;
- Powell, Jason A.;
- Green, Benjamin D.;
- Barry, Emma F.;
- Yuefang Ma;
- Woodcock, Joanna;
- Fitter, Stephen;
- Zannettino, Andrew C. W.;
- Pitson, Stuart M.;
- Hughes, Timothy P.;
- Lopez, Angel F.;
- Shepherd, Peter R.;
- Wei, Andrew H.;
- Ekert, Paul G.;
- Guthridge, Mark A.
Publication type:
Article
Combining properties of different classes of PI3Kα inhibitors to understand the molecular features that confer selectivity.
Published in:
Biochemical Journal, 2017, v. 474, n. 13, p. 2261, doi. 10.1042/BCJ20161098
By:
- Gong, Grace Q.;
- Kendall, Jackie D.;
- Dickson, James M. J.;
- Rewcastle, Gordon W.;
- Buchanan, Christina M.;
- Denny, William A.;
- Shepherd, Peter R.;
- Flanagan, Jack U.
Publication type:
Article
Niclosamide blocks glucagon phosphorylation of Ser<sup>552</sup> on β-catenin in primary rat hepatocytes via PKA signalling.
Published in:
Biochemical Journal, 2016, v. 473, n. 9, p. 1247, doi. 10.1042/BCJ20160121
By:
- Chowdhury, Kamrul H.;
- Wu, Lindsay E.;
- Coleman, James L. J.;
- Smith, Nicola J.;
- Morris, Margaret J.;
- Shepherd, Peter R.;
- Smith, Greg C.
Publication type:
Article
Biochemical Journal strengthens links in Asia.
Published in:
Biochemical Journal, 2014, v. 464, n. 1, p. 1, doi. 10.1042/BJ20140874
By:
- Shepherd, Peter R.
Publication type:
Article
Phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) is an AMPK target participating in contraction-stimulated glucose uptake in skeletal muscle.
Published in:
Biochemical Journal, 2013, v. 455, n. 2, p. 195, doi. 10.1042/BJ20130644
By:
- Yang LIU;
- Yu-Chiang LAI;
- HILL, Elaine V.;
- TYTECA, Donatienne;
- CARPENTIER, Sarah;
- INGVALDSEN, Ada;
- VERTOMMEN, Didier;
- LANTIER, Louise;
- FORETZ, Marc;
- DEQUIEDT, Franck;
- COURTOY, Pierre J.;
- ERNEUX, Christophe;
- VIOLLET, Benoît;
- SHEPHERD, Peter R.;
- TAVARÉ, Jeremy M.;
- JENSEN, Jørgen;
- RIDER, Mark H.
Publication type:
Article
Identification of a pathway by which glucose regulates ß-catenin signalling via the cAMP/protein kinase A pathway in ß-cell models.
Published in:
Biochemical Journal, 2013, v. 449, n. 3, p. 803, doi. 10.1042/BJ20121454
By:
- COGNARD, Emmanuelle;
- DARGAVILLE, Coralie G.;
- HAY, Deborah L.;
- SHEPHERD, Peter R.
Publication type:
Article
Hypothalamic glycogen synthase kinase 3ß has a central role in the regulation of food intake and glucose metabolism.
Published in:
Biochemical Journal, 2012, v. 447, n. 1, p. 175, doi. 10.1042/BJ20120834
By:
- BENZLER, Jonas;
- GANJAM, Goutham K.;
- KRÜGER, Manon;
- PINKENBURG, Olaf;
- KUTSCHKE, Maria;
- STÖHR, Sigrid;
- STEGER, Juliane;
- KOCH, Christiane E.;
- ÖLKRUG, Rebecca;
- SCHWARTZ, Michael W.;
- SHEPHERD, Peter R.;
- GRATTAN, David R.;
- TUPS, Alexander
Publication type:
Article
Definition of the binding mode of a new class of phosphoinositide 3-kinase α-selective inhibitors using in vitro mutagenesis of non-conserved amino acids and kinetic analysis.
Published in:
Biochemical Journal, 2012, v. 444, n. 3, p. 529, doi. 10.1042/BJ20120499
By:
- Zhaohua ZHENG;
- AMRAN, Syazwani I.;
- Jiuxiang ZHU;
- SCHMIDT-KITTLER, Oleg;
- KINZLER, Kenneth W.;
- VOGELSTEIN, Bert;
- SHEPHERD, Peter R.;
- THOMPSON, Philip E.;
- JENNINGS, Ian G.
Publication type:
Article
Over-expression of GLUT4 selectively in adipose tissue in transgenic mice: Implications for nutrient partitioning.
Published in:
Proceedings of the Nutrition Society, 1995, v. 55, n. 1B, p. 191, doi. 10.1079/PNS19960020
By:
- Gnudi, Luigi;
- Shepherd, Peter R.;
- Kahn, Barbara B.
Publication type:
Article
Extended treatment with selective phosphatidylinositol 3-kinase and m TOR inhibitors has effects on metabolism, growth, behaviour and bone strength.
Published in:
FEBS Journal, 2013, v. 280, n. 21, p. 5337, doi. 10.1111/febs.12428
By:
- Smith, Greg C.;
- Ong, Wee ‐ Kiat;
- Costa, Jessica L.;
- Watson, Maureen;
- Cornish, Jillian;
- Grey, Andrew;
- Gamble, Greg D.;
- Dickinson, Michelle;
- Leung, Sophie;
- Rewcastle, Gordon W.;
- Han, Weiping;
- Shepherd, Peter R.
Publication type:
Article
Targeted inhibition of dominant PI3-kinase catalytic isoforms increase expression of stem cell genes in glioblastoma cancer stem cell models.
Published in:
International Journal of Oncology, 2016, v. 49, n. 1, p. 207, doi. 10.3892/ijo.2016.3510
By:
- JONES, NICOLE M.;
- ROWE, MATTHEW R.;
- SHEPHERD, PETER R.;
- MCCONNELL, MELANIE J.
Publication type:
Article
The TSC1-2 tumor suppressor controls insulin-Pl3k signaling via regulation of IRS proteins.
Published in:
Journal of Cell Biology, 2004, v. 166, n. 2, p. 213, doi. 10.1083/jcb.200403069
By:
- Harrington, Laura S.;
- Findlay, Greg M.;
- Gray, Alex;
- Tolkacheva, Tatiana;
- Wigfield, Simon;
- Rebholz, Heike;
- Barnett, Jill;
- Leslie, Nick R.;
- Cheng, Susan;
- Shepherd, Peter R.;
- Gout, Ivan;
- Downes, C. Peter;
- Lamb, Richard F.
Publication type:
Article
Niclosamide reduces glucagon sensitivity via hepatic PKA inhibition in obese mice: Implications for glucose metabolism improvements in type 2 diabetes.
Published in:
Scientific Reports, 2017, p. 40159, doi. 10.1038/srep40159
By:
- Chowdhury, Md. Kamrul Hasan;
- Turner, Nigel;
- Bentley, Nicholas L.;
- Das, Abhirup;
- Wu, Lindsay E.;
- Richani, Dulama;
- Bustamante, Sonia;
- Gilchrist, Robert B.;
- Morris, Margaret J.;
- Shepherd, Peter R.;
- Smith, Greg C.
Publication type:
Article
Conditional Deletion of β-Catenin in the Mediobasal Hypothalamus Impairs Adaptive Energy Expenditure in Response to High-Fat Diet and Exacerbates Diet-Induced Obesity.
Published in:
Journal of Neuroscience, 2024, v. 44, n. 14, p. 1, doi. 10.1523/JNEUROSCI.1666-23.2024
By:
- Rizwan, Mohammed Z.;
- Kamstra, Kaj;
- Pretz, Dominik;
- Shepherd, Peter R.;
- Tups, Alexander;
- Grattan, David R.
Publication type:
Article
PI 3-kinase p110ß: a new target for antithrombotic therapy.
Published in:
Nature Medicine, 2005, v. 11, n. 5, p. 507, doi. 10.1038/nm1232
By:
- Jackson, Shaun P.;
- Schoenwaelder, Simone M.;
- Goncalves, Isaac;
- Nesbitt, Warwick S.;
- Yap, Cindy L.;
- Wright, Christine E.;
- Kenche, Vijaya;
- Anderson, Karen E.;
- Dopheide, Sacha M.;
- Yuping Yuan;
- Sturgeon, Sharelle A.;
- Hishani Prabaharan;
- Thompson, Philip E.;
- Smith, Gregg D.;
- Shepherd, Peter R.;
- Daniele, Nathalie;
- Kulkarni, Suhasini;
- Abbott, Belinda;
- Saylik, Dilek;
- Jones, Catherine
Publication type:
Article
Variable‐Length Ester‐Based Staples for α‐Helical Peptides by Using A Double Thiol‐ene Reaction.
Published in:
Chemistry - A European Journal, 2020, v. 26, n. 47, p. 10826, doi. 10.1002/chem.202001478
By:
- Paterson, Danielle L.;
- Flanagan, Jack U.;
- Shepherd, Peter R.;
- Harris, Paul W. R.;
- Brimble, Margaret A.
Publication type:
Article
G Protein-Coupled Receptor-Mediated Activation of p110b by Gβγ Is Required for Cellular Transformation and Invasiveness.
Published in:
Science Signaling, 2012, v. 5, n. 253, p. 1, doi. 10.1126/scisignal.2003264
By:
- Dbouk, Hashem A.;
- Vadas, Oscar;
- Shymanets, Aliaksei;
- Burke, John E.;
- Salamon, Rachel S.;
- Khalil, Bassem D.;
- Barrett, Mathew O.;
- Waldo, Gary L.;
- Surve, Chinmay;
- Hsueh, Christine;
- Perisic, Olga;
- Harteneck, Christian;
- Shepherd, Peter R.;
- Harden, T. Kendall;
- Smrcka, Alan V.;
- Taussig, Ronald;
- Bresnick, Anne R.;
- Nürnberg, Bernd;
- Williams, Roger L.;
- Backer, Jonathan M.
Publication type:
Article
Structure, function and inhibition of the phosphoinositide 3-kinase p110α enzyme.
Published in:
Biochemical Society Transactions, 2014, v. 42, n. 1, p. 120, doi. 10.1042/BST20130255
By:
- Flanagan, Jack U.;
- Shepherd, Peter R.
Publication type:
Article
Leptin Rapidly Improves Glucose Homeostasis in Obese Mice by Increasing Hypothalamic Insulin Sensitivity.
Published in:
Journal of Neuroscience, 2010, v. 30, n. 48, p. 16180, doi. 10.1523/JNEUROSCI.3202-10.2010
By:
- Koch, Christiane;
- Augustine, Rachael A.;
- Steger, Juliane;
- Ganjam, Goutham K.;
- Benzler, Jonas;
- Pracht, Corinna;
- Lowe, Chrishanthi;
- Schwartz, Michael W.;
- Shepherd, Peter R.;
- Anderson, Greg M.;
- Grattan, David R.;
- Tups, Alexander
Publication type:
Article
The population-specific Thr44Met OCT3 coding variant affects metformin pharmacokinetics with subsequent effects on insulin sensitivity in C57Bl/6J mice.
Published in:
Diabetologia, 2025, v. 68, n. 3, p. 537, doi. 10.1007/s00125-024-06287-1
By:
- Wang, Qian;
- Leask, Megan P.;
- Lee, Kate;
- Jaiswal, Jagdish;
- Kallingappa, Prasanna;
- Dissanayake, Waruni;
- Puli'uvea, Chris;
- O'Sullivan, Conor;
- Watson, Huti;
- Wilcox, Phillip;
- Murphy, Rinki;
- Merry, Troy L.;
- Shepherd, Peter R.
Publication type:
Article
The CREBRF diabetes-protective rs373863828-A allele is associated with enhanced early insulin release in men of Māori and Pacific ancestry.
Published in:
Diabetologia, 2021, v. 64, n. 12, p. 2779, doi. 10.1007/s00125-021-05552-x
By:
- Burden, Hannah J.;
- Adams, Shannon;
- Kulatea, Braydon;
- Wright-McNaughton, Morag;
- Sword, Danielle;
- Ormsbee, Jennifer J.;
- Watene-O'Sullivan, Conor;
- Merriman, Tony R.;
- Knopp, Jennifer L.;
- Chase, J. Geoffrey;
- Krebs, Jeremy D.;
- Hall, Rosemary M.;
- Plank, Lindsay D.;
- Murphy, Rinki;
- Shepherd, Peter R.;
- Merry, Troy L.
Publication type:
Article
Inhibitors of pan-PI3K signaling synergize with BARF or MEK inhibitors to prevent BRA4F-mutant melanoma cell growth.
Published in:
Frontiers in Oncology, 2015, p. 1, doi. 10.3389/fonc.2015.00135
By:
- Sweetlove, Melanie;
- Wrightson, Emma;
- Kolekar, Sharada;
- Rewcastle, Gordon W.;
- Baguley, Bruce C.;
- Shepherd, Peter R.;
- Jamieson, Stephen M. F.;
- Palmieri, Giuseppe;
- Davies, Michael A.
Publication type:
Article
Targeting Class I<sub>A</sub> PI3K Isoforms Selectively Impairs Cell Growth, Survival, and Migration in Glioblastoma.
Published in:
PLoS ONE, 2014, v. 9, n. 4, p. 1, doi. 10.1371/journal.pone.0094132
By:
- Höland, Katrin;
- Boller, Danielle;
- Hagel, Christian;
- Dolski, Silvia;
- Treszl, András;
- Pardo, Olivier E.;
- Ćwiek, Paulina;
- Salm, Fabiana;
- Leni, Zaira;
- Shepherd, Peter R.;
- Styp-Rekowska, Beata;
- Djonov, Valentin;
- von Bueren, André O.;
- Frei, Karl;
- Arcaro, Alexandre
Publication type:
Article
Oncogenic Mutations of p110α Isoform of PI 3-Kinase Upregulate Its Protein Kinase Activity.
Published in:
PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0071337
By:
- Buchanan, Christina M.;
- Dickson, James M. J.;
- Lee, Woo-Jeong;
- Guthridge, Mark A.;
- Kendall, Jackie D.;
- Shepherd, Peter R.
Publication type:
Article
Adiponectin Haploinsufficiency Promotes Mammary Tumor Development in MMTV-PyVT Mice by Modulation of Phosphatase and Tensin Homolog Activities.
Published in:
PLoS ONE, 2009, v. 4, n. 3, p. 1, doi. 10.1371/journal.pone.0004968
By:
- Lam, Janice B. B.;
- Chow, Kim H. M.;
- Aimin Xu;
- Lam, Karen S. L.;
- Jing Liu;
- Nai-Sum Wong;
- Moon, Randall T.;
- Shepherd, Peter R.;
- Cooper, Garth J. S.;
- Yu Wang
Publication type:
Article