Works by SCHOFIELD, Christopher J.

Results: 231

Cover Feature: How Clavulanic Acid Inhibits Serine β‐Lactamases (ChemBioChem 22/2024).

Published in:

ChemBioChem, 2024, v. 25, n. 22, p. 1, doi. 10.1002/cbic.202482202

By:

Lang, Pauline A.;
de Munnik, Mariska;
Oluwole, Abraham O.;
Claridge, Timothy D. W.;
Robinson, Carol V.;
Brem, Jürgen;
Schofield, Christopher J.

Publication type:

Article

How Clavulanic Acid Inhibits Serine β‐Lactamases.

Published in:

ChemBioChem, 2024, v. 25, n. 22, p. 1, doi. 10.1002/cbic.202400280

By:

Lang, Pauline A.;
de Munnik, Mariska;
Oluwole, Abraham O.;
Claridge, Timothy D. W.;
Robinson, Carol V.;
Brem, Jürgen;
Schofield, Christopher J.

Publication type:

Article

Biochemical and Structural Insights into FIH‐Catalysed Hydroxylation of Transient Receptor Potential Ankyrin Repeat Domains.

Published in:

ChemBioChem, 2023, v. 24, n. 4, p. 1, doi. 10.1002/cbic.202200576

By:

Saward, Benjamin G.;
Leissing, Thomas M.;
Clifton, Ian J.;
Tumber, Anthony;
Timperley, Christopher M.;
Hopkinson, Richard J.;
Schofield, Christopher J.

Publication type:

Article

Reducing Agent‐Mediated Nonenzymatic Conversion of 2‐Oxoglutarate to Succinate: Implications for Oxygenase Assays.

Published in:

ChemBioChem, 2020, v. 21, n. 20, p. 2898, doi. 10.1002/cbic.202000185

By:

Khan, Amjad;
Schofield, Christopher J.;
Claridge, Timothy D. W.

Publication type:

Article

Quantitative MS‐Based Proteomics: Comparing the MCF‐7 Cellular Response to Hypoxia and a 2‐Oxoglutarate Analogue.

Published in:

ChemBioChem, 2020, v. 21, n. 11, p. 1647, doi. 10.1002/cbic.201900719

By:

Bush, Jacob T.;
Chan, Mun Chiang;
Mohammed, Shabaz;
Schofield, Christopher J.

Publication type:

Article

A Fluorescence‐Based Assay for Screening β‐Lactams Targeting the Mycobacterium tuberculosis Transpeptidase LdtMt2.

Published in:

ChemBioChem, 2020, v. 21, n. 3, p. 368, doi. 10.1002/cbic.201900379

By:

Munnik, Mariska;
Lohans, Christopher T.;
Langley, Gareth W.;
Bon, Corentin;
Brem, Jürgen;
Schofield, Christopher J.

Publication type:

Article

Studies on the Substrate Selectivity of the Hypoxia‐Inducible Factor Prolyl Hydroxylase 2 Catalytic Domain.

Published in:

ChemBioChem, 2018, v. 19, n. 21, p. 2262, doi. 10.1002/cbic.201800246

By:

Abboud, Martine I.;
Chowdhury, Rasheduzzaman;
Leung, Ivanhoe K. H.;
Lippl, Kerstin;
Loenarz, Christoph;
Claridge, Timothy D. W.;
Schofield, Christopher J.

Publication type:

Article

Lysine‐241 Has a Role in Coupling 2OG Turnover with Substrate Oxidation During KDM4‐Catalysed Histone Demethylation.

Published in:

ChemBioChem, 2018, v. 19, n. 9, p. 917, doi. 10.1002/cbic.201800002

By:

Hancock, Rebecca L.;
Abboud, Martine I.;
Smart, Tristan J.;
Flashman, Emily;
Kawamura, Akane;
Schofield, Christopher J.;
Hopkinson, Richard J.

Publication type:

Article

Use of Methylmalonyl-CoA Epimerase in Enhancing Crotonase Stereoselectivity.

Published in:

ChemBioChem, 2016, v. 17, n. 6, p. 471, doi. 10.1002/cbic.201500644

By:

Hamed, Refaat B.;
Gomez‐Castellanos, J. Ruben;
Sean Froese, D.;
Krysztofinska, Ewelina;
Yue, Wyatt W.;
Schofield, Christopher J.

Publication type:

Article

Dynamic Combinatorial Chemistry Employing Boronic Acids/Boronate Esters Leads to Potent Oxygenase Inhibitors.

Published in:

Angewandte Chemie, 2012, v. 124, n. 27, p. 6776, doi. 10.1002/ange.201202000

By:

Demetriades, Marina;
Leung, Ivanhoe K. H.;
Chowdhury, Rasheduzzaman;
Chan, Mun Chiang;
McDonough, Michael A.;
Yeoh, Kar Kheng;
Tian, Ya-Min;
Claridge, Timothy D. W.;
Ratcliffe, Peter J.;
Woon, Esther C. Y.;
Schofield, Christopher J.

Publication type:

Article

Conversion of Cysteine into Dehydroalanine Enables Access to Synthetic Histones Bearing Diverse Post-Translational Modifications.

Published in:

Angewandte Chemie, 2012, v. 124, n. 8, p. 1871, doi. 10.1002/ange.201106432

By:

Chalker, Justin M.;
Lercher, Lukas;
Rose, Nathan R.;
Schofield, Christopher J.;
Davis, Benjamin G.

Publication type:

Article

Linking of 2-Oxoglutarate and Substrate Binding Sites Enables Potent and Highly Selective Inhibition of JmjC Histone Demethylases.

Published in:

Angewandte Chemie, 2012, v. 124, n. 7, p. 1663, doi. 10.1002/ange.201107833

By:

Woon, Esther C. Y.;
Tumber, Anthony;
Kawamura, Akane;
Hillringhaus, Lars;
Ge, Wei;
Rose, Nathan R.;
Ma, Jerome H. Y.;
Chan, Mun Chiang;
Walport, Louise J.;
Che, Ka Hing;
Ng, Stanley S.;
Marsden, Brian D.;
Oppermann, Udo;
McDonough, Michael A.;
Schofield, Christopher J.

Publication type:

Article

Iron-Mediated Cleavage of CC Bonds in Vicinal Tricarbonyl Compounds in Water.

Published in:

Angewandte Chemie, 2009, v. 121, n. 15, p. 2834, doi. 10.1002/ange.200806296

By:

Mecinović, Jasmin;
Hamed, Refaat B.;
Schofield, Christopher J.

Publication type:

Article

Thioester Hydrolysis and CC Bond Formation by Carboxymethylproline Synthase from the Crotonase Superfamily.

Published in:

Angewandte Chemie, 2008, v. 120, n. 48, p. 9462, doi. 10.1002/ange.200803906

By:

Batchelar, Edward T.;
Hamed, Refaat B.;
Ducho, Christian;
Claridge, Timothy D. W.;
Edelmann, Mariola J.;
Kessler, Benedikt;
Schofield, Christopher J.

Publication type:

Article

Syntheses of [2-13C] and [1,2-13C] labelled α-ketoglutaric acid.

Published in:

Journal of Labelled Compounds & Radiopharmaceuticals, 1989, v. 27, n. 9, p. 1091, doi. 10.1002/jlcr.2580270914

By:

Baldwin, Jack E.;
Adlington, Robert M.;
Russell, Mark A.;
Schofield, Christopher J.;
Wood, Mark E.

Publication type:

Article

Biocatalytic production of bicyclic β-lactams with three contiguous chiral centres using engineered crotonases.

Published in:

Communications Chemistry, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42004-018-0106-z

By:

Hamed, Refaat B.;
Gomez-Castellanos, J. Ruben;
Henry, Luc;
Warhaut, Sven;
Claridge, Timothy D. W.;
Schofield, Christopher J.

Publication type:

Article

JmjC catalysed histone H2a N-methyl arginine demethylation and C4-arginine hydroxylation reveals importance of sequence-reactivity relationships.

Published in:

Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-07183-5

By:

Bonnici, Joanna;
Oueini, Razanne;
Salah, Eidarus;
Johansson, Catrine;
Pires, Elisabete;
Abboud, Martine;
Dawber, Robert S.;
Tumber, Anthony;
Rabe, Patrick;
Saraç, Hilal;
Schofield, Christopher J.;
Kawamura, Akane

Publication type:

Article

Author Correction: Normal tissue radioprotection by amifostine via Warburg-type effects.

Published in:

2025

By:

Koukourakis, Michael I.;
Giatromanolaki, Alexandra;
Zois, Christos E.;
Kalamida, Dimitra;
Pouliliou, Stamatia;
Karagounis, Ilias V.;
Yeh, Tzu-Lan;
Abboud, Martine I.;
Claridge, Timothy D. W.;
Schofield, Christopher J.;
Sivridis, Efthimios;
Simopoulos, Costantinos;
Tokmakidis, Savvas P.;
Harris, Adrian L.

Publication type:

Correction Notice

SNM1A is crucial for efficient repair of complex DNA breaks in human cells.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-49583-5

By:

Swift, Lonnie P.;
Lagerholm, B. Christoffer;
Henderson, Lucy R.;
Ratnaweera, Malitha;
Baddock, Hannah T.;
Sengerova, Blanka;
Lee, Sook;
Cruz-Migoni, Abimael;
Waithe, Dominic;
Renz, Christian;
Ulrich, Helle D.;
Newman, Joseph A.;
Schofield, Christopher J.;
McHugh, Peter J.

Publication type:

Article

Inactivation of 1-aminocyclopropane-1-carboxylate (ACC) oxidase.

Published in:

Journal of Experimental Botany, 1994, v. 45, n. 5, p. 521

By:

Smith, Julian J.;
Zhang, Zhi Hong;
Schofield, Christopher J.;
John, Philip;
Baldwin, Jack E.

Publication type:

Article

Rhodanine hydrolysis leads to potent thioenolate mediated metallo-β-lactamase inhibition.

Published in:

Nature Chemistry, 2014, v. 6, n. 12, p. 1084, doi. 10.1038/nchem.2110

By:

Brem, Jürgen;
van Berkel, Sander S.;
Aik, WeiShen;
Rydzik, Anna M.;
Avison, Matthew B.;
Pettinati, Ilaria;
Umland, Klaus-Daniel;
Kawamura, Akane;
Spencer, James;
Claridge, Timothy D. W.;
McDonough, Michael A.;
Schofield, Christopher J.

Publication type:

Article

Stereoselective C-C bond formation catalysed by engineered carboxymethylproline synthases.

Published in:

Nature Chemistry, 2011, v. 3, n. 5, p. 365, doi. 10.1038/nchem.1011

By:

Hamed, Refaat B.;
Gomez-Castellanos, J. Ruben;
Thalhammer, Armin;
Harding, Daniel;
Ducho, Christian;
Claridge, Timothy D. W.;
Schofield, Christopher J.

Publication type:

Article

Front Cover: Origins of Catalysis in Non‐Heme Fe(II)/2‐Oxoglutarate‐Dependent Histone Lysine Demethylase KDM4A with Differently Methylated Histone H3 Peptides (Chem. Eur. J. 3/2025).

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 3, p. 1, doi. 10.1002/chem.202580301

By:

Devadas, Sudheesh;
Thomas, Midhun George;
Rifayee, Simahudeen Bathir Jaber Sathik;
Varada, Bhargav;
White, Walter;
Sommer, Ethan;
Campbell, Kylin;
Schofield, Christopher J.;
Christov, Christo Z.

Publication type:

Article

Origins of Catalysis in Non‐Heme Fe(II)/2‐Oxoglutarate‐Dependent Histone Lysine Demethylase KDM4A with Differently Methylated Histone H3 Peptides.

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 3, p. 1, doi. 10.1002/chem.202403989

By:

Devadas, Sudheesh;
Thomas, Midhun George;
Rifayee, Simahudeen Bathir Jaber Sathik;
Varada, Bhargav;
White, Walter;
Sommer, Ethan;
Campbell, Kylin;
Schofield, Christopher J.;
Christov, Christo Z.

Publication type:

Article

Cover Feature: Catalysis by KDM6 Histone Demethylases – A Synergy between the Non‐Heme Iron(II) Center, Second Coordination Sphere, and Long‐Range Interactions (Chem. Eur. J. 51/2023).

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 51, p. 1, doi. 10.1002/chem.202302510

By:

Rifayee, Simahudeen Bathir Jaber Sathik;
Chaturvedi, Shobhit S.;
Warner, Cait;
Wildey, Jon;
White, Walter;
Thompson, Martin;
Schofield, Christopher J.;
Christov, Christo Z.

Publication type:

Article

Catalysis by KDM6 Histone Demethylases – A Synergy between the Non‐Heme Iron(II) Center, Second Coordination Sphere, and Long‐Range Interactions.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 51, p. 1, doi. 10.1002/chem.202301305

By:

Rifayee, Simahudeen Bathir Jaber Sathik;
Chaturvedi, Shobhit S.;
Warner, Cait;
Wildey, Jon;
White, Walter;
Thompson, Martin;
Schofield, Christopher J.;
Christov, Christo Z.

Publication type:

Article

Dioxygen Binding Is Controlled by the Protein Environment in Non‐heme FeII and 2‐Oxoglutarate Oxygenases: A Study on Histone Demethylase PHF8 and an Ethylene‐Forming Enzyme.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 24, p. 1, doi. 10.1002/chem.202300138

By:

Chaturvedi, Shobhit S.;
Thomas, Midhun George;
Bathir Jaber Sathik Rifayee, Simahudeen;
White, Walter;
Wildey, Jon;
Warner, Cait;
Schofield, Christopher J.;
Hu, Jian;
Hausinger, Robert P.;
Karabencheva‐Christova, Tatayana G.;
Christov, Christo Z.

Publication type:

Article

Front Cover: Dioxygen Binding Is Controlled by the Protein Environment in Non‐heme FeII and 2‐Oxoglutarate Oxygenases: A Study on Histone Demethylase PHF8 and an Ethylene‐Forming Enzyme (Chem. Eur. J. 24/2023).

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 24, p. 1, doi. 10.1002/chem.202300138

By:

Chaturvedi, Shobhit S.;
Thomas, Midhun George;
Rifayee, Simahudeen Bathir Jaber Sathik;
White, Walter;
Wildey, Jon;
Warner, Cait;
Schofield, Christopher J.;
Hu, Jian;
Hausinger, Robert P.;
Karabencheva‐Christova, Tatayana G.;
Christov, Christo Z.

Publication type:

Article

Dioxygen Binding Is Controlled by the Protein Environment in Non‐heme FeII and 2‐Oxoglutarate Oxygenases: A Study on Histone Demethylase PHF8 and an Ethylene‐Forming Enzyme.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 24, p. 1, doi. 10.1002/chem.202300138

By:

Chaturvedi, Shobhit S.;
Thomas, Midhun George;
Rifayee, Simahudeen Bathir Jaber Sathik;
White, Walter;
Wildey, Jon;
Warner, Cait;
Schofield, Christopher J.;
Hu, Jian;
Hausinger, Robert P.;
Karabencheva‐Christova, Tatayana G.;
Christov, Christo Z.

Publication type:

Article

One‐Step Synthesis of Photoaffinity Probes for Live‐Cell MS‐Based Proteomics.

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 71, p. 17880, doi. 10.1002/chem.202102036

By:

Fallon, David J.;
Lehmann, Stephanie;
Chung, Chun‐wa;
Phillipou, Alex;
Eberl, Christian;
Fantom, Ken G. M.;
Zappacosta, Francesca;
Patel, Vipulkumar K.;
Bantscheff, Marcus;
Schofield, Christopher J.;
Tomkinson, Nicholas C. O.;
Bush, Jacob T.

Publication type:

Article

What Is the Catalytic Mechanism of Enzymatic Histone N‐Methyl Arginine Demethylation and Can It Be Influenced by an External Electric Field?

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 46, p. 11750, doi. 10.1002/chem.202102158

By:

Ramanan, Rajeev;
Waheed, Sodiq O.;
Schofield, Christopher J.;
Christov, Christo Z.

Publication type:

Article

Front Cover: What Is the Catalytic Mechanism of Enzymatic Histone N‐Methyl Arginine Demethylation and Can It Be Influenced by an External Electric Field? (Chem. Eur. J. 46/2021).

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 46, p. 11746, doi. 10.1002/chem.202102157

By:

Ramanan, Rajeev;
Waheed, Sodiq O.;
Schofield, Christopher J.;
Christov, Christo Z.

Publication type:

Article

What Is the Catalytic Mechanism of Enzymatic Histone N‐Methyl Arginine Demethylation and Can It Be Influenced by an External Electric Field?

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 46, p. 11827, doi. 10.1002/chem.202101174

By:

Ramanan, Rajeev;
Waheed, Sodiq O.;
Schofield, Christopher J.;
Christov, Christo Z.

Publication type:

Article

Electrochemical Nanoreactor Provides a Comprehensive View of Isocitrate Dehydrogenase Cancer‐drug Kinetics.

Published in:

Angewandte Chemie, 2023, v. 135, n. 42, p. 1, doi. 10.1002/ange.202309149

By:

Herold, Ryan A.;
Schofield, Christopher J.;
Armstrong, Fraser A.

Publication type:

Article

In Situ Inhibitor Synthesis and Screening by Fluorescence Polarization: An Efficient Approach for Accelerating Drug Discovery.

Published in:

Angewandte Chemie, 2022, v. 134, n. 45, p. 1, doi. 10.1002/ange.202211510

By:

Li, Zhihong;
Wu, Yue;
Zhen, Shuai;
Su, Kaijun;
Zhang, Linjian;
Yang, Fulai;
McDonough, Michael A.;
Schofield, Christopher J.;
Zhang, Xiaojin

Publication type:

Article

Human Oxygenase Variants Employing a Single Protein FeII Ligand Are Catalytically Active.

Published in:

Angewandte Chemie, 2021, v. 133, n. 26, p. 14778, doi. 10.1002/ange.202103711

By:

Brasnett, Amelia;
Pfeffer, Inga;
Brewitz, Lennart;
Chowdhury, Rasheduzzaman;
Nakashima, Yu;
Tumber, Anthony;
McDonough, Michael A.;
Schofield, Christopher J.

Publication type:

Article

Allosteric Inhibition of the SARS‐CoV‐2 Main Protease: Insights from Mass Spectrometry Based Assays**.

Published in:

Angewandte Chemie, 2020, v. 132, n. 52, p. 23750, doi. 10.1002/ange.202010316

By:

El‐Baba, Tarick J.;
Lutomski, Corinne A.;
Kantsadi, Anastassia L.;
Malla, Tika R.;
John, Tobias;
Mikhailov, Victor;
Bolla, Jani R.;
Schofield, Christopher J.;
Zitzmann, Nicole;
Vakonakis, Ioannis;
Robinson, Carol V.

Publication type:

Article

Non‐Hydrolytic β‐Lactam Antibiotic Fragmentation by l,d‐Transpeptidases and Serine β‐Lactamase Cysteine Variants.

Published in:

Angewandte Chemie, 2019, v. 131, n. 7, p. 2012, doi. 10.1002/ange.201809424

By:

Lohans, Christopher T.;
Chan, H. T. Henry;
Malla, Tika R.;
Kumar, Kiran;
Kamps, Jos J. A. G.;
McArdle, Darius J. B.;
van Groesen, Emma;
de Munnik, Mariska;
Tooke, Catherine L.;
Spencer, James;
Paton, Robert S.;
Brem, Jürgen;
Schofield, Christopher J.

Publication type:

Article

A comparison of 2‐hydroxyglutarate detection at 3 and 7 T with long‐TE semi‐LASER.

Published in:

NMR in Biomedicine, 2018, v. 31, n. 3, p. 1, doi. 10.1002/nbm.3886

By:

Berrington, Adam;
Voets, Natalie L.;
Larkin, Sarah J.;
de Pennington, Nick;
Mccullagh, James;
Stacey, Richard;
Schofield, Christopher J.;
Jezzard, Peter;
Clare, Stuart;
Cadoux‐Hudson, Tom;
Plaha, Puneet;
Ansorge, Olaf;
Emir, Uzay E.

Publication type:

Article

Adventures in Defining Roles of Oxygenases in the Regulation of Protein Biosynthesis.

Published in:

Chemical Record, 2018, v. 18, n. 12, p. 1760, doi. 10.1002/tcr.201800056

By:

Walport, Louise J.;
Schofield, Christopher J.

Publication type:

Article

Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity.

Published in:

Nature, 2007, v. 448, n. 7149, p. 87, doi. 10.1038/nature05971

By:

Ng, Stanley S.;
Kavanagh, Kathryn L.;
McDonough, Michael A.;
Butler, Danica;
Pilka, Ewa S.;
Lienard, Benoit M. R.;
Bray, James E.;
Savitsky, Pavel;
Gileadi, Opher;
von Delft, Frank;
Rose, Nathan R.;
Offer, John;
Scheinost, Johanna C.;
Borowski, Tomasz;
Sundstrom, Michael;
Schofield, Christopher J.;
Oppermann, Udo

Publication type:

Article

Human prolyl hydroxylase domain 2 reacts with O2 and 2-oxoglutarate to enable formation of inactive Fe(III).2OG.hypoxia-inducible-factor α complexes.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-75761-y

By:

Fiorini, Giorgia;
Marshall, Stephen A.;
Figg Jr., William D.;
Myers, William K.;
Brewitz, Lennart;
Schofield, Christopher J.

Publication type:

Article

Activity‐based proteomics uncovers suppressed hydrolases and a neo‐functionalised antibacterial enzyme at the plant–pathogen interface.

Published in:

New Phytologist, 2024, v. 241, n. 1, p. 394, doi. 10.1111/nph.18857

By:

Sueldo, Daniela J.;
Godson, Alice;
Kaschani, Farnusch;
Krahn, Daniel;
Kessenbrock, Till;
Buscaill, Pierre;
Schofield, Christopher J.;
Kaiser, Markus;
van der Hoorn, Renier A. L.

Publication type:

Article

Broad‐range metalloprotease profiling in plants uncovers immunity provided by defence‐related metalloenzyme.

Published in:

New Phytologist, 2022, v. 235, n. 3, p. 1287, doi. 10.1111/nph.18200

By:

Morimoto, Kyoko;
Krahn, Daniel;
Kaschani, Farnusch;
Hopkinson‐Woolley, Digby;
Gee, Anna;
Buscaill, Pierre;
Mohammed, Shabaz;
Sieber, Stephan A.;
Cravatt, Benjamin F.;
Schofield, Christopher J.;
van der Hoorn, Renier A. L.

Publication type:

Article

2-Oxoglutarate derivatives can selectively enhance or inhibit the activity of human oxygenases.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26673-2

By:

Nakashima, Yu;
Brewitz, Lennart;
Tumber, Anthony;
Salah, Eidarus;
Schofield, Christopher J.

Publication type:

Article

The catalytic domains of all human KDM5 JmjC demethylases catalyse N‐methyl arginine demethylation.

Published in:

FEBS Letters, 2023, v. 597, n. 7, p. 933, doi. 10.1002/1873-3468.14586

By:

Bonnici, Joanna;
Oueini, Razanne;
Salah, Eidarus;
Johansson, Catrine;
Schofield, Christopher J.;
Kawamura, Akane

Publication type:

Article

Mechanistic and structural studies of KDM‐catalysed demethylation of histone 1 isotype 4 at lysine 26.

Published in:

FEBS Letters, 2018, v. 592, n. 19, p. 3264, doi. 10.1002/1873-3468.13231

By:

Walport, Louise J.;
Hopkinson, Richard J.;
Chowdhury, Rasheduzzaman;
Zhang, Yijia;
Bonnici, Joanna;
Schiller, Rachel;
Kawamura, Akane;
Schofield, Christopher J.

Publication type:

Article

Molecular dynamics simulations of the acyl-enzyme and the tetrahedral intermediate in the deacylation step of serine proteases.

Published in:

Proteins, 2002, v. 47, n. 3, p. 357, doi. 10.1002/prot.10097

By:

Topf, Maya;
Várnai, Péter;
Schofield, Christopher J.;
Richards, W. Graham

Publication type:

Article

Autocatalysed oxidative modifications to 2-oxoglutarate dependent oxygenases.

Published in:

FEBS Journal, 2012, v. 279, n. 9, p. 1563, doi. 10.1111/j.1742-4658.2012.08496.x

By:

Mantri, Monica;
Zhang, Zhihong;
McDonough, Michael A.;
Schofield, Christopher J.

Publication type:

Article

Factor-inhibiting hypoxia-inducible factor (FIH) catalyses the post-translational hydroxylation of histidinyl residues within ankyrin repeat domains.

Published in:

FEBS Journal, 2011, v. 278, n. 7, p. 1086, doi. 10.1111/j.1742-4658.2011.08022.x

By:

Yang, Ming;
Chowdhury, Rasheduzzaman;
Ge, Wei;
Hamed, Refaat B.;
McDonough, Michael A.;
Claridge, Timothy D. W.;
Kessler, Benedikt M.;
Cockman, Matthew E.;
Ratcliffe, Peter J.;
Schofield, Christopher J.

Publication type:

Article