Works by SAVAGE, MARTIN

Results: 78

The Digital-Human Interface: An Essential Combination for Clinical Progress.

Published in:

2025

By:

Savage, Martin O.

Publication type:

Editorial

GH Resistance Is a Component of Idiopathic Short Stature: Implications for rhGH Therapy.

Published in:

Frontiers in Endocrinology, 2021, v. 12, p. 1, doi. 10.3389/fendo.2021.781044

By:

Savage, Martin O.;
Storr, Helen L.

Publication type:

Article

Expanding the Spectrum of Mutations in GH1 and GHRHR: Genetic Screening in a Large Cohort of Patients with Congenital Isolated Growth Hormone Deficiency.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2009, v. 94, n. 9, p. 3191, doi. 10.1210/jc.2008-2783

By:

Alatzoglou, Kyriaki S.;
Turton, James P.;
Kelberman, Daniel;
Clayton, Peter E.;
Mehta, Ameeta;
Buchanan, Charles;
Aylwin, Simon;
Crowne, Elisabeth C.;
Christesen, Henrik T.;
Hertel, Niels T.;
Trainer, Peter J.;
Savage, Martin O.;
Raza, Jamal;
Banerjee, Kausik;
Sinha, Sunil K.;
Ten, Svetlana;
Mushtaq, Talat;
Brauner, Raja;
Cheetham, Timothy D.;
Hindmarsh, Peter C.

Publication type:

Article

The diagnosis of Cushing's syndrome: an Endocrine Society Clinical Practice Guideline.

Published in:

2008

By:

Nieman, Lynnette K;
Biller, Beverly M K;
Findling, James W;
Newell-Price, John;
Savage, Martin O;
Stewart, Paul M;
Montori, Victor M

Publication type:

journal article

Pharmacokinetic Studies of Recombinant Human Insulin-Like Growth Factor I (rhIGF-I)/rhIGF-Binding Protein-3 Complex Administered to Patients with Growth Hormone Insensitivity Syndrome.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2006, v. 91, n. 4, p. 1246, doi. 10.1210/jc.2005-1017

By:

Camacho-Hübner, Cecilia;
Rose, Stephen;
Preece, Michael A.;
Sleevi, Mark;
Storr, Helen L.;
Miraki-Moud, Farideh;
Minuto, Francesco;
Frystyk, Jan;
Rogol, Alan;
Allan, Geoffrey;
Sommer, Andreas;
Savage, Martin O.

Publication type:

Article

Prepubertal Cushing’s Disease Is More Common in Males, But There Is No Increase in Severity at Diagnosis.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2004, v. 89, n. 8, p. 3818, doi. 10.1210/jc.2003-031531

By:

STORR, HELEN L.;
ISIDORI, ANDREA M.;
MONSON, JOHN P.;
BESSER, G. MICHAEL;
GROSSMAN, ASHLEY B.;
SAVAGE, MARTIN O.

Publication type:

Article

Association between Insulin-Like Growth Factor I (IGF-I) Polymorphisms, Circulating IGF-I, and Pre- and Postnatal Growth in Two European Small for Gestational Age Populations.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2003, v. 88, n. 10, p. 4805, doi. 10.1210/jc.2003-030563

By:

JOHNSTON, LINDA B.;
DAHLGREN, JOVANNA;
LEGER, JULIANE;
GELANDER, LARS;
SAVAGE, MARTIN O.;
CZERNICHOW, PAUL;
WIKLAND, KERSTIN ALBERTSSON;
CLARK, ADRIAN J. L.

Publication type:

Article

Clinical and Endocrine Responses to Pituitary Radiotherapy in Pediatric Cushing’s Disease: An Effective Second-Line Treatment.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2003, v. 88, n. 1, p. 34, doi. 10.1210/jc.2002-021032

By:

STORR, HELEN L.;
PLOWMAN, P. NICHOLAS;
CARROLL, PAUL V.;
OIS, INGE FRANC¸;
KRASSAS, GERASIMOS E.;
AFSHAR, FARHAD;
BESSER, G. MICHAEL;
GROSSMAN, ASHLEY B.;
SAVAGE, MARTIN O.

Publication type:

Article

IGF-I Is Critical for Normal Vascularization of the Human Retina.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2002, v. 87, n. 7, p. 3413, doi. 10.1210/jcem.87.7.8629

By:

HELLSTRÖM, ANN;
CARLSSON, BJÖRN;
NIKLASSON, AIMON;
SEGNESTAM, KARIN;
BOGUSZEWSKI, MARGARET;
DE LACERDA, LUIZ;
SAVAGE, MARTIN;
SVENSSON, ELISABETH;
SMITH, LOIS;
WEINBERGER, DOV;
WIKLAND, KERSTIN ALBERTSSON;
LARON, ZVI

Publication type:

Article

Polymorphism in the IGF-I Gene: Clinical Relevance for Short Children Born Small for Gestational Age (SGA).

Published in:

Journal of Clinical Endocrinology & Metabolism, 2002, v. 87, n. 6, p. 2720, doi. 10.1210/jcem.87.6.8673

By:

ARENDS, NICOLETTE;
JOHNSTON, LINDA;
HOKKEN-KOELEGA, ANITA;
VAN DUIJN, CORNELIA;
DE RIDDER, MARIA;
SAVAGE, MARTIN;
CLARK, ADRIAN

Publication type:

Article

Relative Contributions of Inferior Petrosal Sinus Sampling and Pituitary Imaging in the Investigation of Children and Adolescents with ACTH-Dependent Cushing’s Syndrome.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2001, v. 86, n. 12, p. 5711, doi. 10.1210/jc.86.12.5711

By:

LIENHARDT, ANNE;
GROSSMAN, ASHLEY B.;
DACIE, JANET E.;
EVANSON, JANE;
HUEBNER, ANGELA;
AFSHAR, FARHAD;
PLOWMAN, P. NICHOLAS;
BESSER, G. MICHAEL;
SAVAGE, MARTIN O.

Publication type:

Article

Growth Hormone Therapy and Growth in Children with Noonan’s Syndrome: Results of 3 Years’ Follow-Up.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2001, v. 86, n. 5, p. 1953, doi. 10.1210/jcem.86.5.7468

By:

MACFARLANE, CATHERINE E.;
BROWN, DONALD C.;
JOHNSTON, LINDA B.;
PATTON, MICHAEL A.;
DUNGER, DAVID B.;
SAVAGE, MARTIN O.;
MCKENNA, WILLIAM J.;
KELNAR, CHRISTOPHER J. H.

Publication type:

Article

Linear Growth and Final Height after Treatment for Cushing’s Disease in Childhood.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2000, v. 85, n. 9, p. 3262, doi. 10.1210/jcem.85.9.6817

By:

LEBRETHON, MARIE-CHRISTINE;
GROSSMAN, ASHLEY B.;
AFSHAR, FARHAD;
PLOWMAN, P. NICHOLAS;
BESSER,, G. MICHAEL;
SAVAGE, MARTIN O.

Publication type:

Article

A Combined Test Using Desmopressin and Corticotropin- Releasing Hormone in the Differential Diagnosis of Cushing’s Syndrome.

Published in:

Journal of Clinical Endocrinology & Metabolism, 1997, v. 82, n. 1, p. 176, doi. 10.1210/jc.82.1.176

By:

NEWELL-PRICE, JOHN;
PERRY, LES;
MEDBAK, SAMI;
MONSON, JOHN;
SAVAGE, MARTIN;
BESSER, MICHAEL;
GROSSMAN, ASHLEY

Publication type:

Article

VERY CHARMING BARYONS.

Published in:

International Journal of Modern Physics A: Particles & Fields; Gravitation; Cosmology; Nuclear Physics, 1991, v. 6, n. 10, p. 1701, doi. 10.1142/S0217751X91000903

By:

SAVAGE, MARTIN J.;
SPRINGER, ROXANNE P.

Publication type:

Article

Abnormal linear growth in paediatric adrenal diseases: Pathogenesis, prevalence and management.

Published in:

Clinical Endocrinology, 2020, v. 92, n. 2, p. 98, doi. 10.1111/cen.14131

By:

Minnetti, Marianna;
Caiulo, Silvana;
Ferrigno, Rosario;
Baldini‐Ferroli, Barbara;
Bottaro, Giorgia;
Gianfrilli, Daniele;
Sbardella, Emilia;
De Martino, Maria Cristina;
Savage, Martin O.

Publication type:

Article

Endonasal endoscopic transsphenoidal pituitary surgery: early experience and outcome in paediatric Cushing's disease.

Published in:

Clinical Endocrinology, 2014, v. 80, n. 2, p. 270, doi. 10.1111/cen.12275

By:

Storr, Helen L.;
Drake, William M.;
Evanson, Jane;
Matson, Matthew;
Berney, Dan M.;
Grossman, Ashley B.;
Akker, Scott A.;
Monson, John P.;
Alusi, Ghassan;
Savage, Martin O.;
Sabin, Ian

Publication type:

Article

Identification and management of poor response to growth-promoting therapy in children with short stature.

Published in:

Clinical Endocrinology, 2012, v. 77, n. 2, p. 169, doi. 10.1111/j.1365-2265.2012.04420.x

By:

Bang, Peter;
Ahmed, S. Faisal;
Argente, Jesús;
Backeljauw, Philippe;
Bettendorf, Markus;
Bona, Gianni;
Coutant, Régis;
Rosenfeld, Ron G.;
Walenkamp, Marie-José;
Savage, Martin O.

Publication type:

Article

The continuum of growth hormone–IGF-I axis defects causing short stature: diagnostic and therapeutic challenges.

Published in:

Clinical Endocrinology, 2010, v. 72, n. 6, p. 721, doi. 10.1111/j.1365-2265.2009.03775.x

By:

Savage, Martin O.;
Burren, Christine P.;
Rosenfeld, Ron G.

Publication type:

Article

Homozygous nonsense and frameshift mutations of the ACTH receptor in children with familial glucocorticoid deficiency (FGD) are not associated with long-term mineralocorticoid deficiency.

Published in:

Clinical Endocrinology, 2009, v. 71, n. 2, p. 171, doi. 10.1111/j.1365-2265.2008.03511.x

By:

Li F. Chan;
Metherell, Louise A.;
Krude, Heiko;
Ball, Colin;
O'Riordan, Stephen M. P.;
Costigan, Colm;
Lynch, Sally A.;
Savage, Martin O.;
Cavarzere, Paolo;
Clark, Adrian J. L.

Publication type:

Article

The variability of responses to growth hormone therapy in children with short stature.

Published in:

Indian Journal of Endocrinology & Metabolism, 2012, v. 16, p. S178, doi. 10.4103/2230-8210.104034

By:

Savage, Martin O.;
Bang, Peter

Publication type:

Article

Pediatric Cushing's Disease: Management Issues.

Published in:

Indian Journal of Endocrinology & Metabolism, 2012, v. 16, p. S171, doi. 10.4103/2230-8210.104032

By:

Savage, Martin O.;
Storr, Helen L.

Publication type:

Article

Phenotypic spectrum and responses to recombinant human IGF1 (rhIGF1) therapy in patients with homozygous intronic pseudoexon growth hormone receptor mutation.

Published in:

European Journal of Endocrinology, 2018, v. 178, n. 5, p. 481, doi. 10.1530/EJE-18-0042

By:

Chatterjee, Sumana;
Shapiro, Lucy;
Rose, Stephen J.;
Mushtaq, Talat;
Clayton, Peter E.;
Ten, Svetlana B.;
Bhangoo, Amrit;
Kumbattae, Uma;
Dias, Renuka;
Savage, Martin O.;
Metherel, Louise A.;
Storr, Helen L.

Publication type:

Article

Whole-exome sequencing gives additional benefits compared to candidate gene sequencing in the molecular diagnosis of children with growth hormone or IGF-1 insensitivity.

Published in:

European Journal of Endocrinology, 2017, v. 177, n. 6, p. 485, doi. 10.1530/EJE-17-0453

By:

Shapiro, Lucy;
Chatterjee, Sumana;
Ramadan, Dina G.;
Davies, Kate M.;
Savage, Martin O.;
Metherell, Louise A.;
Storr, Helen L.

Publication type:

Article

Paediatric Cushing's disease.

Published in:

European Journal of Endocrinology, 2015, v. 173, n. 1, p. R35, doi. 10.1530/EJE-15-0013

By:

Storr, Helen L.;
Savage, Martin O.

Publication type:

Article

Genetic characterisation of a cohort of children clinically labelled as GH or IGF1 insensitive: diagnostic value of serum IGF1 and height at presentation.

Published in:

European Journal of Endocrinology, 2015, v. 172, n. 2, p. 151, doi. 10.1530/EJE-14-0541

By:

Storr, Helen L.;
Dunkel, Leo;
Kowalczyk, Julia;
Savage, Martin O.;
Metherell, Louise A.

Publication type:

Article

The evolving biology of growth and metabolism.

Published in:

European Journal of Endocrinology, 2007, v. 157, p. S1, doi. 10.1530/EJE-07-0370

By:

Cianfarani, Stefano;
Bouc, Yves Le;
Savage, Martin

Publication type:

Article

Idiopathic short stature: will genetics influence the choice between GH and IGF-I therapy?

Published in:

European Journal of Endocrinology, 2007, v. 157, p. S33, doi. 10.1530/EJE-07-0292

By:

Savage, Martin O.;
Camacho-Hübner, Cecilia;
David, Alessia;
Metherell, Louise A.;
Hwa, Vivian;
Rosenfeld, Ron G.;
Clark, Adrian J. L.

Publication type:

Article

Factors influencing cure by transsphenoidal selective adenomectomy in paediatric Cushings disease.

Published in:

European Journal of Endocrinology, 2005, v. 152, n. 6, p. 825, doi. 10.1530/eje.1.01921

By:

Helen L Storr;
Farhad Afshar;
Matthew Matson;
Ian Sabin;
Kate M Davies;
Jane Evanson;
P Nicholas Plowman;
G Michael Besser;
John P Monson;
Ashley B Grossman;
Martin O Savage

Publication type:

Article

Balanced assessment of growth disorders using clinical, endocrinological, and genetic approaches.

Published in:

Annals of Pediatric Endocrinology & Metabolism, 2021, v. 26, n. 4, p. 218, doi. 10.6065/apem.2142208.104

By:

Savage, Martin Oswald;
Storr, Helen Louise

Publication type:

Article

Editorial: Controversies in growth hormone treatment and diagnosis.

Published in:

Frontiers in Endocrinology, 2022, v. 13, p. 1, doi. 10.3389/fendo.2022.1013872

By:

Rapaport, Robert;
Savage, Martin O.

Publication type:

Article

Nonclassical GH Insensitivity: Characterization of Mild Abnormalities of GH Action.

Published in:

Endocrine Reviews, 2019, v. 40, n. 2, p. 476, doi. 10.1210/er.2018-00146

By:

Storr, Helen L;
Chatterjee, Sumana;
Metherell, Louise A;
Foley, Corinne;
Rosenfeld, Ron G;
Backeljauw, Philippe F;
Dauber, Andrew;
Savage, Martin O;
Hwa, Vivian

Publication type:

Article

Late-Onset Isolated Growth Hormone Deficiency.

Published in:

JCEM Case Reports, 2023, v. 1, n. 2, p. 1, doi. 10.1210/jcemcr/luad011

By:

Samuels, Julie G;
Chimatapu, Sri Nikhita;
Savage, Martin O;
Rapaport, Robert

Publication type:

Article

Managing Paediatric Growth Disorders: Integrating Technology Into a Personalised Approach.

Published in:

Journal of Clinical Research in Pediatric Endocrinology, 2020, v. 12, n. 3, p. 225, doi. 10.4274/jcrpe.galenos.2019.2019.0153

By:

Child, Jenny;
Davies, Christine;
Frost, Katie;
McDermid, Eleanor;
Pidcock, Rachel;
Weinman, John;
Savage, Martin O.

Publication type:

Article

Achieving Optimal Short- and Long-term Responses to Paediatric Growth Hormone Therapy.

Published in:

Journal of Clinical Research in Pediatric Endocrinology, 2019, v. 11, n. 4, p. 329, doi. 10.4274/jcrpe.galenos.2019.2019.0088

By:

Wit, Jan M.;
Deeb, Asma;
Bin-Abbas, Bassam;
Al Mutair, Angham;
Koledova, Ekaterina;
Savage, Martin O.

Publication type:

Article

Artificial intelligence in paediatric endocrinology: conflict or cooperation.

Published in:

Journal of Pediatric Endocrinology & Metabolism, 2024, v. 37, n. 3, p. 209, doi. 10.1515/jpem-2023-0554

By:

Dimitri, Paul;
Savage, Martin O.

Publication type:

Article

Growth Hormone Receptor (GHR) 6O Pseudoexon Activation: A Novel Cause of Severe Growth Hormone Insensitivity.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2022, v. 107, n. 1, p. e401, doi. 10.1210/clinem/dgab550

By:

Cottrell, Emily;
Maharaj, Avinaash;
Williams, Jack;
Chatterjee, Sumana;
Cirillo, Grazia;
del Giudice, Emanuele Miraglia;
Festa, Adalgisa;
Palumbo, Stefania;
Capalbo, Donatella;
Salerno, Mariacarolina;
Pignata, Claudio;
Savage, Martin O.;
Schilbach, Katharina;
Bidlingmaier, Martin;
Hwa, Vivian;
Metherel, Louise A.;
Grandone, Anna;
Storr, Helen L.

Publication type:

Article

Genetic Characterization of Short Stature Patients With Overlapping Features of Growth Hormone Insensitivity Syndromes.

Published in:

2021

By:

Andrews, Afiya;
Maharaj, Avinaash;
Cottrell, Emily;
Chatterjee, Sumana;
Shah, Pratik;
Denvir, Louise;
Dumic, Katja;
Bossowski, Artur;
Mushtaq, Talat;
Vukovic, Rade;
Didi, Mohamed;
Shaw, Nick;
Metherell, Louise A.;
Savage, Martin O.;
Storr, Helen L.

Publication type:

journal article

Long-term outcomes of children treated for Cushing's disease: a single center experience.

Published in:

Pituitary, 2016, v. 19, n. 6, p. 612, doi. 10.1007/s11102-016-0756-8

By:

Yordanova, Galina;
Martin, Lee;
Afshar, Farhad;
Sabin, Ian;
Alusi, Ghassan;
Plowman, Nicholas;
Riddoch, Fiona;
Evanson, Jane;
Matson, Matthew;
Grossman, Ashley;
Akker, Scott;
Monson, John;
Drake, William;
Savage, Martin;
Storr, Helen

Publication type:

Article

Diagnosis and treatment of pediatric Cushing’s disease.

Published in:

Pituitary, 2007, v. 10, n. 4, p. 365, doi. 10.1007/s11102-007-0056-4

By:

Savage, Martin;
Storr, Helen;
Chan, Li;
Grossman, Ashley

Publication type:

Article

Adherence to r-hGH Therapy in Pediatric Growth Hormone Deficiency: Current Perspectives on How Patient-Generated Data Will Transform r-hGH Treatment Towards Integrated Care.

Published in:

Patient Preference & Adherence, 2022, v. 16, p. 1663, doi. 10.2147/PPA.S271453

By:

Savage, Martin O;
Fernandez-Luque, Luis;
Graham, Selina;
van Dommelen, Paula;
Araujo, Matheus;
de Arriba, Antonio;
Koledova, Ekaterina

Publication type:

Article

Book Reviews.

Published in:

1994

By:

McNicholas, Fiona;
Robinson, Peter H.;
Savage, Martin O.;
Hobson, R. Peter

Publication type:

Book Review

Book Reviews.

Published in:

1994

By:

Davis, Hilton;
While, Alison E.;
Holt, Kenneth E.;
Lansdown, Richard;
Savage, Martin O.;
Price, Elizabeth H.;
Hurley, Anne;
Polnay, Leon;
Edwards, Dawn

Publication type:

Book Review

Cushing's syndrome in infancy due to ectopic ACTH secretion by a sacro-coccygeal teratoma.

Published in:

Journal of Pediatric Endocrinology & Metabolism, 2017, v. 30, n. 4, p. 475, doi. 10.1515/jpem-2016-0339

By:

Rydzewska, Marta;
Krawczuk-Rybak, Maryna;
Zajkowska, Adrianna;
Jurczuk, Natalia;
Polnik, Dariusz;
Szalecki, Mieczysław;
Moszczyńska, Elżbieta;
Savage, Martin O.;
Bossowski, Artur

Publication type:

Article

Fundamental principles of clinical and biochemical evaluation underlie the diagnosis and therapy of Cushing's syndrome.

Published in:

Journal of Pediatric Endocrinology & Metabolism, 2014, v. 27, n. 11/12, p. 1029, doi. 10.1515/jpem-2014-0400

By:

Savage, Martin O.;
Storr, Helen L.

Publication type:

Article

Novel Growth Hormone Receptor Mutation in a Chinese Patient with Laron Syndrome.

Published in:

Journal of Pediatric Endocrinology & Metabolism, 2005, v. 18, n. 2, p. 209, doi. 10.1515/jpem.2005.18.2.209

By:

Hui, Hamilton N. T.;
Metherell, Louise A.;
Ng, K. L.;
Savage, Martin O.;
Camacho-Hübner, Cecilia;
Clark, Adrian J. L.

Publication type:

Article

Intranasal Human Growth Hormone (hGH) Induces IGF-1 Levels Comparable With Subcutaneous Injection With Lower Systemic Exposure to hGH in Healthy Volunteers.

Published in:

2015

By:

Lewis, Andrew L;
Jordan, Faron;
Patel, Tina;
Jeffery, Kirk;
King, Gareth;
Savage, Martin;
Shalet, Stephen;
Illum, Lisbeth

Publication type:

journal article

Treatment of Cushing's Syndrome: An Endocrine Society Clinical Practice Guideline.

Published in:

2015

By:

Nieman, Lynnette K;
Biller, Beverly M K;
Findling, James W;
Murad, M Hassan;
Newell-Price, John;
Savage, Martin O;
Tabarin, Antoine;
Endocrine Society

Publication type:

journal article

Thioredoxin Reductase 2 (TXNRD2) mutation associated with familial glucocorticoid deficiency (FGD).

Published in:

2014

By:

Prasad, Rathi;
Chan, Li F;
Hughes, Claire R;
Kaski, Juan P;
Kowalczyk, Julia C;
Savage, Martin O;
Peters, Catherine J;
Nathwani, Nisha;
Clark, Adrian J L;
Storr, Helen L;
Metherell, Louise A

Publication type:

journal article

Effects of long-term treatment with recombinant growth hormone on growth outcome in children born small for gestational age: a systematic review.

Published in:

Reviews in Endocrine & Metabolic Disorders, 2025, v. 26, n. 2, p. 147, doi. 10.1007/s11154-024-09911-y

By:

Ferrigno, Rosario;
Savage, Martin O.;
Cioffi, Daniela;
Pellino, Valeria;
Savanelli, Maria Cristina;
Klain, Antonella

Publication type:

Article