Works by SAHASRABUDHE, PARAG

Results: 39
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    N6-methyladenosine in DNA promotes genome stability.

    Published in:
    eLife, 2025, p. 1, doi. 10.7554/eLife.101626
    By:
    • Conti, Brooke A.;
    • Novikov, Leo;
    • Deyan Tong;
    • Qing Xiang;
    • Vigil, Savon;
    • McLellan, Thomas J.;
    • Chuong Nguyen;
    • De La Cruz, Nancy;
    • Veettil, Reshma T.;
    • Pradhan, Prashant;
    • Sahasrabudhe, Parag;
    • Arroyo, Jason D.;
    • Lei Shang;
    • Sabari, Benjamin R.;
    • Shields, David J.;
    • Oppikofer, Mariano
    Publication type:
    Article
    29

    Binding site elucidation and structure guided design of macrocyclic IL-17A antagonists.

    Published in:
    Scientific Reports, 2016, p. 30859, doi. 10.1038/srep30859
    By:
    • Liu, Shenping;
    • Dakin, Leslie A.;
    • Xing, Li;
    • Withka, Jane M.;
    • Sahasrabudhe, Parag V.;
    • Li, Wei;
    • Banker, Mary Ellen;
    • Balbo, Paul;
    • Shanker, Suman;
    • Chrunyk, Boris A.;
    • Guo, Zuojun;
    • Chen, Jinshan M.;
    • Young, Jennifer A.;
    • Bai, Guoyun;
    • Starr, Jeremy T.;
    • Wright, Stephen W.;
    • Bussenius, Joerg;
    • Tan, Sheng;
    • Gopalsamy, Ariamala;
    • Lefker, Bruce A.
    Publication type:
    Article
    30

    Inhibiting complex IL-17A and IL-17RA interactions with a linear peptide.

    Published in:
    Scientific Reports, 2016, p. 26071, doi. 10.1038/srep26071
    By:
    • Liu, Shenping;
    • Desharnais, Joel;
    • Sahasrabudhe, Parag V.;
    • Jin, Ping;
    • Li, Wei;
    • Oates, Bryan D.;
    • Shanker, Suman;
    • Banker, Mary Ellen;
    • Chrunyk, Boris A.;
    • Song, Xi;
    • Feng, Xidong;
    • Griffor, Matt;
    • Jimenez, Judith;
    • Chen, Gang;
    • Tumelty, David;
    • Bhat, Abhijit;
    • Bradshaw, Curt W.;
    • Woodnutt, Gary;
    • Lappe, Rodney W.;
    • Thorarensen, Atli
    Publication type:
    Article
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    Inhibiting peptidylarginine deiminases (PAD1-4) by targeting a Ca<sup>2+</sup> dependent allosteric binding site.

    Published in:
    Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-59919-4
    By:
    • Dakin, Leslie A.;
    • Xing, Li;
    • Hall, Justin;
    • Ding, Weidong;
    • Vajdos, Felix F.;
    • Pelker, Jeffrey W.;
    • Ramsey, Simeon;
    • Balbo, Paul;
    • Sahasrabudhe, Parag V.;
    • Banker, Mary Ellen;
    • Choi, Won Young;
    • Wright, Stephen W.;
    • Chang, Jeanne S.;
    • Curto, John M.;
    • Davoren, Jennifer E.;
    • Drozda, Susan E.;
    • Fennell, Kimberly F.;
    • Futatsugi, Kentaro;
    • Kortum, Steve;
    • Lee, Katherine L.
    Publication type:
    Article
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    Preclinical characterization of the Omicron XBB.1.5-adapted BNT162b2 COVID-19 vaccine.

    Published in:
    NPJ Vaccines, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41541-024-01013-9
    By:
    • Modjarrad, Kayvon;
    • Che, Ye;
    • Chen, Wei;
    • Wu, Huixian;
    • Cadima, Carla I.;
    • Muik, Alexander;
    • Maddur, Mohan S.;
    • Tompkins, Kristin R.;
    • Martinez, Lyndsey T.;
    • Cai, Hui;
    • Ramos, Minah;
    • Mensah, Sonia;
    • Cumbia, Brittney;
    • Falcao, Larissa;
    • McKeen, Andrew P.;
    • Chang, Jeanne S.;
    • Fennell, Kimberly F.;
    • Huynh, Kevin W.;
    • McLellan, Thomas J.;
    • Sahasrabudhe, Parag V.
    Publication type:
    Article
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    Probing the enzyme kinetics, allosteric modulation and activation of α1- and α2-subunit-containing AMP-activated protein kinase (AMPK) heterotrimeric complexes by pharmacological and physiological activators.

    Published in:
    Biochemical Journal, 2016, v. 473, n. 5, p. 581, doi. 10.1042/BJ20151051
    By:
    • Rajamohan, Francis;
    • Reyes, Allan R.;
    • Frisbie, Richard K.;
    • Hoth, Lise R.;
    • Sahasrabudhe, Parag;
    • Magyar, Rachelle;
    • Landro, James A.;
    • Withka, Jane M.;
    • Caspers, Nicole L.;
    • Calabrese, Matthew F.;
    • Ward, Jessica;
    • Kurumbail, Ravi G.
    Publication type:
    Article
    38

    Small molecule branched-chain ketoacid dehydrogenase kinase (BDK) inhibitors with opposing effects on BDK protein levels.

    Published in:
    Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-40536-y
    By:
    • Roth Flach, Rachel J.;
    • Bollinger, Eliza;
    • Reyes, Allan R.;
    • Laforest, Brigitte;
    • Kormos, Bethany L.;
    • Liu, Shenping;
    • Reese, Matthew R.;
    • Martinez Alsina, Luis A.;
    • Buzon, Leanne;
    • Zhang, Yuan;
    • Bechle, Bruce;
    • Rosado, Amy;
    • Sahasrabudhe, Parag V.;
    • Knafels, John;
    • Bhattacharya, Samit K.;
    • Omoto, Kiyoyuki;
    • Stansfield, John C.;
    • Hurley, Liam D.;
    • Song, LouJin;
    • Luo, Lina
    Publication type:
    Article
    39

    Small molecule branched-chain ketoacid dehydrogenase kinase (BDK) inhibitors with opposing effects on BDK protein levels.

    Published in:
    Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-40536-y
    By:
    • Roth Flach, Rachel J.;
    • Bollinger, Eliza;
    • Reyes, Allan R.;
    • Laforest, Brigitte;
    • Kormos, Bethany L.;
    • Liu, Shenping;
    • Reese, Matthew R.;
    • Martinez Alsina, Luis A.;
    • Buzon, Leanne;
    • Zhang, Yuan;
    • Bechle, Bruce;
    • Rosado, Amy;
    • Sahasrabudhe, Parag V.;
    • Knafels, John;
    • Bhattacharya, Samit K.;
    • Omoto, Kiyoyuki;
    • Stansfield, John C.;
    • Hurley, Liam D.;
    • Song, LouJin;
    • Luo, Lina
    Publication type:
    Article