Works by Sánchez‐Murcia, Pedro A.

Results: 32

Vibrio cholerae's ToxRS bile sensing system.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.88721

By:

Gubensäk, Nina;
Sagmeister, Theo;
Buhlheller, Christoph;
Di Geronimo, Bruno;
Wagner, Gabriel E.;
Petrowitsch, Lukas;
Gräwert, Melissa A.;
Rotzinger, Markus;
Berger, Tamara M. Ismael;
Schäfer, Jan;
Usón, Isabel;
Reidl, Joachim;
Sánchez-Murcia, Pedro A.;
Zangger, Klaus;
Pavkov-Keller, Tea

Publication type:

Article

Enzymatic β-elimination in natural product O- and C-glycoside deglycosylation.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-42750-0

By:

Bitter, Johannes;
Pfeiffer, Martin;
Borg, Annika J. E.;
Kuhlmann, Kirill;
Pavkov-Keller, Tea;
Sánchez-Murcia, Pedro A.;
Nidetzky, Bernd

Publication type:

Article

PyrAtes: Modular Organic Salts with Large Stokes Shifts for Fluo‐rescence Microscopy.

Published in:

Angewandte Chemie International Edition, 2024, v. 63, n. 19, p. 1, doi. 10.1002/anie.202318127

By:

Saridakis, Iakovos;
Riomet, Margaux;
Belleza, Oliver J. V.;
Coussanes, Guilhem;
Singer, Nadja K.;
Kastner, Nina;
Xiao, Yi;
Smith, Elliot;
Tona, Veronica;
de la Torre, Aurélien;
Lopes, Eric F.;
Sánchez‐Murcia, Pedro A.;
González, Leticia;
Sitte, Harald H.;
Maulide, Nuno

Publication type:

Article

Back Cover: Unravelling the Turn‐On Fluorescence Mechanism of a Fluorescein‐Based Probe in GABAA Receptors (Angew. Chem. Int. Ed. 30/2022).

Published in:

Angewandte Chemie International Edition, 2022, v. 61, n. 30, p. 1, doi. 10.1002/anie.202205198

By:

Singer, Nadja K.;
Sánchez‐Murcia, Pedro A.;
Ernst, Margot;
González, Leticia

Publication type:

Article

Unravelling the Turn‐On Fluorescence Mechanism of a Fluorescein‐Based Probe in GABAA Receptors.

Published in:

Angewandte Chemie International Edition, 2022, v. 61, n. 30, p. 1, doi. 10.1002/anie.202205198

By:

Singer, Nadja K.;
Sánchez‐Murcia, Pedro A.;
Ernst, Margot;
González, Leticia

Publication type:

Article

A Supramolecular Stabilizer of the 14‐3‐3ζ/ERα Protein‐Protein Interaction with a Synergistic Mode of Action.

Published in:

Angewandte Chemie International Edition, 2020, v. 59, n. 13, p. 5284, doi. 10.1002/anie.201914517

By:

Gigante, Alba;
Sijbesma, Eline;
Sánchez‐Murcia, Pedro A.;
Hu, Xiaoyu;
Bier, David;
Bäcker, Sandra;
Knauer, Shirley;
Gago, Federico;
Ottmann, Christian;
Schmuck, Carsten

Publication type:

Article

A new view of missense mutations in α‐mannosidosis using molecular dynamics conformational ensembles.

Published in:

Protein Science: A Publication of the Protein Society, 2025, v. 34, n. 4, p. 1, doi. 10.1002/pro.70080

By:

Mandl, Špela;
Di Geronimo, Bruno;
Alonso‐Gil, Santiago;
Grininger, Christoph;
George, Gibu;
Ferstl, Ulrika;
Herzog, Sereina Annik;
Žagrović, Bojan;
Nusshold, Christoph;
Pavkov‐Keller, Tea;
Sánchez‐Murcia, Pedro A.

Publication type:

Article

Are the Hydantoin-1,3,5-triazine 5-HT6R Ligands a Hope to a Find New Procognitive and Anti-Obesity Drug? Considerations Based on Primary In Vivo Assays and ADME-Tox Profile In Vitro.

Published in:

Molecules, 2019, v. 24, n. 24, p. 4472, doi. 10.3390/molecules24244472

By:

Lubelska, Annamaria;
Latacz, Gniewomir;
Jastrzębska-Więsek, Magdalena;
Kotańska, Magdalena;
Kurczab, Rafał;
Partyka, Anna;
Marć, Małgorzata Anna;
Wilczyńska, Daria;
Doroz-Płonka, Agata;
Łażewska, Dorota;
Wesołowska, Anna;
Kieć-Kononowicz, Katarzyna;
Handzlik, Jadwiga;
Sánchez-Murcia, Pedro A.;
Gigante, Alba;
Pérez, Víctor Sebastián

Publication type:

Article

Design, Synthesis and Biological Evaluation of New Piperazin-4-yl-(acetyl-thiazolidine-2,4-dione) Norfloxacin Analogues as Antimicrobial Agents.

Published in:

Molecules, 2019, v. 24, n. 21, p. 3959, doi. 10.3390/molecules24213959

By:

Marc, Gabriel;
Araniciu, Cătălin;
Oniga, Smaranda Dafina;
Vlase, Laurian;
Pîrnău, Adrian;
Nadăș, George Cosmin;
Novac, Cristiana Ștefania;
Matei, Ioana Adriana;
Chifiriuc, Mariana Carmen;
Măruțescu, Luminița;
Oniga, Ovidiu;
Sánchez-Murcia, Pedro A.

Publication type:

Article

Silyl Assistance in the Intramolecular Addition of Pyridyl Radicals onto Pyridines and Quinolines.

Published in:

European Journal of Organic Chemistry, 2016, v. 2016, n. 10, p. 1891, doi. 10.1002/ejoc.201600170

By:

Filace, Fabiana;
Sánchez ‐ Murcia, Pedro A.;
Sucunza, David;
Pérez ‐ Redondo, Adrián;
Álvarez ‐ Buílla, Julio;
Gago, Federico;
Burgos, Carolina

Publication type:

Article

Cover Feature: Ligand 1H NMR Chemical Shifts as Accurate Reporters for Protein‐Ligand Binding Interfaces in Solution (ChemPhysChem 1/2024).

Published in:

ChemPhysChem, 2024, v. 25, n. 1, p. 1, doi. 10.1002/cphc.202300636

By:

Platzer, Gerald;
Ptaszek, Aleksandra L.;
Böttcher, Jark;
Fuchs, Julian E.;
Geist, Leonhard;
Braun, Daniel;
McConnell, Darryl B.;
Konrat, Robert;
Sánchez‐Murcia, Pedro A.;
Mayer, Moriz

Publication type:

Article

Ligand 1H NMR Chemical Shifts as Accurate Reporters for Protein‐Ligand Binding Interfaces in Solution.

Published in:

ChemPhysChem, 2024, v. 25, n. 1, p. 1, doi. 10.1002/cphc.202300636

By:

Platzer, Gerald;
Ptaszek, Aleksandra L.;
Böttcher, Jark;
Fuchs, Julian E.;
Geist, Leonhard;
Braun, Daniel;
McConnell, Darryl B.;
Konrat, Robert;
Sánchez‐Murcia, Pedro A.;
Mayer, Moriz

Publication type:

Article

Probing the Dimerization Interface of Leishmania infantum Trypanothione Reductase with Site-Directed Mutagenesis and Short Peptides.

Published in:

ChemBioChem, 2013, v. 14, n. 10, p. 1212, doi. 10.1002/cbic.201200744

By:

Toro, Miguel A.;
Sánchez‐Murcia, Pedro A.;
Moreno, David;
Ruiz‐Santaquiteria, Marta;
Alzate, Juan Fernando;
Negri, Ana;
Camarasa, María‐José;
Gago, Federico;
Velázquez, Sonsoles;
Jiménez‐Ruiz, Antonio

Publication type:

Article

Unravelling the covalent binding of zampanolide and taccalonolide AJ to a minimalist representation of a human microtubule.

Published in:

Journal of Computer-Aided Molecular Design, 2019, v. 33, n. 7, p. 627, doi. 10.1007/s10822-019-00208-w

By:

Sánchez-Murcia, Pedro A.;
Mills, Alberto;
Cortés-Cabrera, Álvaro;
Gago, Federico

Publication type:

Article

Structural rationale for the cross-resistance of tumor cells bearing the A399V variant of elongation factor eEF1A1 to the structurally unrelated didemnin B, ternatin, nannocystin A and ansatrienin B.

Published in:

Journal of Computer-Aided Molecular Design, 2017, v. 31, n. 10, p. 915, doi. 10.1007/s10822-017-0066-x

By:

Sánchez-Murcia, Pedro;
Cortés-Cabrera, Álvaro;
Gago, Federico

Publication type:

Article

Characterization of an atypical, thermostable, organic solvent- and acid-tolerant 2′-deoxyribosyltransferase from Chroococcidiopsis thermalis.

Published in:

Applied Microbiology & Biotechnology, 2018, v. 102, n. 16, p. 6947, doi. 10.1007/s00253-018-9134-y

By:

Del Arco, Jon;
Sánchez-Murcia, Pedro Alejandro;
Mancheño, José Miguel;
Gago, Federico;
Fernández-Lucas, Jesús

Publication type:

Article

Enzymatic Synthesis of Therapeutic Nucleosides using a Highly Versatile Purine Nucleoside 2'‐DeoxyribosylTransferase from Trypanosoma brucei.

Published in:

ChemCatChem, 2018, v. 10, n. 19, p. 4406, doi. 10.1002/cctc.201800775

By:

Pérez, Elena;
Fernández‐Lucas, Jesús;
Sánchez‐Murcia, Pedro A.;
Jordaan, Justin;
Blanco, María Dolores;
Mancheño, José Miguel;
Gago, Federico

Publication type:

Article

Identification of NEK3 and MOK as novel targets for lithium.

Published in:

Chemical Biology & Drug Design, 2019, v. 93, n. 5, p. 965, doi. 10.1111/cbdd.13487

By:

Bravo, Ana;
Lucio, Héctor;
Sánchez‐Murcia, Pedro A.;
Jiménez‐Ruiz, Antonio;
Petrone, Paula M.;
Gago, Federico;
Cortés Cabrera, Alvaro

Publication type:

Article

Insights into the Biological Activity and Bio‐Interaction Properties of Nanoscale Imine‐Based 2D and 3D Covalent Organic Frameworks.

Published in:

Advanced Science, 2024, v. 11, n. 44, p. 1, doi. 10.1002/advs.202407391

By:

Ye, Hao;
Franco, Carlos;
Aboouf, Mostafa A.;
Thiersch, Markus;
Sevim, Semih;
Llacer‐Wintle, Joaquin;
Veciana, Andrea;
Llauradó‐Capdevila, Gemma;
Wang, Kaiyuan;
Chen, Xiang‐Zhong;
Tang, Qiao;
Matheu, Roc;
Wendel‐Garcia, Pedro D.;
Sánchez‐Murcia, Pedro A.;
Nelson, Bradley J.;
Luo, Cong;
Puigmartí‐Luis, Josep;
Pané, Salvador

Publication type:

Article

PyrAt‐Verbindungen: Modulare organische Salze mit großen Stokes‐Verschiebungen für die Fluoreszenzmikroskopie.

Published in:

Angewandte Chemie, 2024, v. 136, n. 19, p. 1, doi. 10.1002/ange.202318127

By:

Saridakis, Iakovos;
Riomet, Margaux;
Belleza, Oliver J. V.;
Coussanes, Guilhem;
Singer, Nadja K.;
Kastner, Nina;
Xiao, Yi;
Smith, Elliot;
Tona, Veronica;
de la Torre, Aurélien;
Lopes, Eric F.;
Sánchez‐Murcia, Pedro A.;
González, Leticia;
Sitte, Harald H.;
Maulide, Nuno

Publication type:

Article

Rücktitelbild: Unravelling the Turn‐On Fluorescence Mechanism of a Fluorescein‐Based Probe in GABAA Receptors (Angew. Chem. 30/2022).

Published in:

Angewandte Chemie, 2022, v. 134, n. 30, p. 1, doi. 10.1002/ange.202205198

By:

Singer, Nadja K.;
Sánchez‐Murcia, Pedro A.;
Ernst, Margot;
González, Leticia

Publication type:

Article

Unravelling the Turn‐On Fluorescence Mechanism of a Fluorescein‐Based Probe in GABAA Receptors.

Published in:

Angewandte Chemie, 2022, v. 134, n. 30, p. 1, doi. 10.1002/ange.202205198

By:

Singer, Nadja K.;
Sánchez‐Murcia, Pedro A.;
Ernst, Margot;
González, Leticia

Publication type:

Article

A Supramolecular Stabilizer of the 14‐3‐3ζ/ERα Protein‐Protein Interaction with a Synergistic Mode of Action.

Published in:

Angewandte Chemie, 2020, v. 132, n. 13, p. 5322, doi. 10.1002/ange.201914517

By:

Gigante, Alba;
Sijbesma, Eline;
Sánchez‐Murcia, Pedro A.;
Hu, Xiaoyu;
Bier, David;
Bäcker, Sandra;
Knauer, Shirley;
Gago, Federico;
Ottmann, Christian;
Schmuck, Carsten

Publication type:

Article

Structure-based domain assignment in Leishmania infantum EndoG: characterization of a pH-dependent regulatory switch and a C-terminal extension that largely dictates DNA substrate preferences.

Published in:

Nucleic Acids Research, 2017, v. 45, n. 15, p. 9030, doi. 10.1093/nar/gkx629

By:

Oliva, Cristina;
Sánchez-Murcia, Pedro A.;
Rico, Eva;
Bravo, Ana;
Menéndez, Margarita;
Gago, Federico;
Jiménez-Ruiz1, Antonio

Publication type:

Article

Functional Characterization and Structural Analysis of NADH Oxidase Mutants from Thermus thermophilus HB27: Role of Residues 166, 174, and 194 in the Catalytic Properties and Thermostability.

Published in:

Microorganisms, 2019, v. 7, n. 11, p. 515, doi. 10.3390/microorganisms7110515

By:

Rocha-Martin, Javier;
Sánchez-Murcia, Pedro A.;
López-Gallego, Fernando;
Hidalgo, Aurelio;
Berenguer, José;
Guisan, José M.

Publication type:

Article

Modular Architecture and Unique Teichoic Acid Recognition Features of Choline-Binding Protein L (CbpL) Contributing to Pneumococcal Pathogenesis.

Published in:

Scientific Reports, 2016, p. 38094, doi. 10.1038/srep38094

By:

Gutiérrez-Fernández, Javier;
Saleh, Malek;
Alcorlo, Martín;
Gómez-Mejía, Alejandro;
Pantoja-Uceda, David;
Treviño, Miguel A.;
Voß, Franziska;
Abdullah, Mohammed R.;
Galán-Bartual, Sergio;
Seinen, Jolien;
Sánchez-Murcia, Pedro A.;
Gago, Federico;
Bruix, Marta;
Hammerschmidt, Sven;
Hermoso, Juan A.

Publication type:

Article

Translation Elongation Factor eEF1A2 is a Novel Anticancer Target for the Marine Natural Product Plitidepsin.

Published in:

Scientific Reports, 2016, p. 35100, doi. 10.1038/srep35100

By:

Losada, Alejandro;
Muñoz-Alonso, María José;
García, Carolina;
Sánchez-Murcia, Pedro A.;
Martínez-Leal, Juan Fernando;
Domínguez, Juan Manuel;
Lillo, M. Pilar;
Gago, Federico;
Galmarini, Carlos M.

Publication type:

Article

Design, synthesis and structure-activity relationship (SAR) studies of an unusual class of non-cationic fatty amine-tripeptide conjugates as novel synthetic antimicrobial agents.

Published in:

Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1428409

By:

Hernández-Ortiz, Noelia;
Sánchez-Murcia, Pedro A.;
Gil-Campillo, Celia;
Domenech, Mirian;
Lucena-Agell, Daniel;
Hortigüela, Rafael;
Velázquez, Sonsoles;
José Camarasa, María;
Bustamante, Noemí;
de Castro, Sonia;
Menéndez, Margarita

Publication type:

Article

Deciphering the Chemical Basis of Fluorescence of a Selenium‐Labeled Uracil Probe when Bound at the Bacterial Ribosomal A‐Site.

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 15, p. 4927, doi. 10.1002/chem.202004818

By:

Cardenas, Gustavo;
Menger, Maximilian F. S. J.;
Ramos‐Berdullas, Nicolás;
Sánchez‐Murcia, Pedro A.

Publication type:

Article

Spiropyran Meets Guanine Quadruplexes: Isomerization Mechanism and DNA Binding Modes of Quinolizidine‐Substituted Spiropyran Probes.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 57, p. 13039, doi. 10.1002/chem.202001586

By:

Avagliano, Davide;
Sánchez‐Murcia, Pedro A.;
González, Leticia

Publication type:

Article

The repertoire of iron superoxide dismutases from Leishmania infantum as targets in the search for therapeutic agents against leishmaniasis.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2024, v. 39, n. 1, p. 1, doi. 10.1080/14756366.2024.2377586

By:

García-Soriano, Juan Carlos;
de Lucio, Héctor;
Elvira-Blázquez, Daniel;
Alcón-Calderón, Mercedes;
Sanz del Olmo, Natalia;
Sánchez-Murcia, Pedro A.;
Ortega, Paula;
de la Mata, Francisco Javier;
Jiménez-Ruiz, Antonio

Publication type:

Article

Molecular Basis of NDT-Mediated Activation of Nucleoside-Based Prodrugs and Application in Suicide Gene Therapy.

Published in:

Biomolecules (2218-273X), 2021, v. 11, n. 1, p. 120, doi. 10.3390/biom11010120

By:

Acosta, Javier;
Pérez, Elena;
Sánchez-Murcia, Pedro A.;
Fillat, Cristina;
Fernández-Lucas, Jesús

Publication type:

Article

Works by Sánchez‐Murcia, Pedro A.

Vibrio cholerae's ToxRS bile sensing system.

Enzymatic β-elimination in natural product O- and C-glycoside deglycosylation.

PyrAtes: Modular Organic Salts with Large Stokes Shifts for Fluo‐rescence Microscopy.

Back Cover: Unravelling the Turn‐On Fluorescence Mechanism of a Fluorescein‐Based Probe in GABA<sub>A</sub> Receptors (Angew. Chem. Int. Ed. 30/2022).

Unravelling the Turn‐On Fluorescence Mechanism of a Fluorescein‐Based Probe in GABA<sub>A</sub> Receptors.

A Supramolecular Stabilizer of the 14‐3‐3ζ/ERα Protein‐Protein Interaction with a Synergistic Mode of Action.

A new view of missense mutations in α‐mannosidosis using molecular dynamics conformational ensembles.

Are the Hydantoin-1,3,5-triazine 5-HT6R Ligands a Hope to a Find New Procognitive and Anti-Obesity Drug? Considerations Based on Primary In Vivo Assays and ADME-Tox Profile In Vitro.

Design, Synthesis and Biological Evaluation of New Piperazin-4-yl-(acetyl-thiazolidine-2,4-dione) Norfloxacin Analogues as Antimicrobial Agents.

Silyl Assistance in the Intramolecular Addition of Pyridyl Radicals onto Pyridines and Quinolines.

Cover Feature: Ligand <sup>1</sup>H NMR Chemical Shifts as Accurate Reporters for Protein‐Ligand Binding Interfaces in Solution (ChemPhysChem 1/2024).

Ligand <sup>1</sup>H NMR Chemical Shifts as Accurate Reporters for Protein‐Ligand Binding Interfaces in Solution.

Probing the Dimerization Interface of Leishmania infantum Trypanothione Reductase with Site-Directed Mutagenesis and Short Peptides.

Unravelling the covalent binding of zampanolide and taccalonolide AJ to a minimalist representation of a human microtubule.

Structural rationale for the cross-resistance of tumor cells bearing the A399V variant of elongation factor eEF1A1 to the structurally unrelated didemnin B, ternatin, nannocystin A and ansatrienin B.

Characterization of an atypical, thermostable, organic solvent- and acid-tolerant 2′-deoxyribosyltransferase from Chroococcidiopsis thermalis.

Enzymatic Synthesis of Therapeutic Nucleosides using a Highly Versatile Purine Nucleoside 2'‐DeoxyribosylTransferase from Trypanosoma brucei.

Identification of NEK3 and MOK as novel targets for lithium.

Insights into the Biological Activity and Bio‐Interaction Properties of Nanoscale Imine‐Based 2D and 3D Covalent Organic Frameworks.

PyrAt‐Verbindungen: Modulare organische Salze mit großen Stokes‐Verschiebungen für die Fluoreszenzmikroskopie.

Rücktitelbild: Unravelling the Turn‐On Fluorescence Mechanism of a Fluorescein‐Based Probe in GABA<sub>A</sub> Receptors (Angew. Chem. 30/2022).

Unravelling the Turn‐On Fluorescence Mechanism of a Fluorescein‐Based Probe in GABA<sub>A</sub> Receptors.

A Supramolecular Stabilizer of the 14‐3‐3ζ/ERα Protein‐Protein Interaction with a Synergistic Mode of Action.

Structure-based domain assignment in Leishmania infantum EndoG: characterization of a pH-dependent regulatory switch and a C-terminal extension that largely dictates DNA substrate preferences.

Functional Characterization and Structural Analysis of NADH Oxidase Mutants from Thermus thermophilus HB27: Role of Residues 166, 174, and 194 in the Catalytic Properties and Thermostability.

Modular Architecture and Unique Teichoic Acid Recognition Features of Choline-Binding Protein L (CbpL) Contributing to Pneumococcal Pathogenesis.

Translation Elongation Factor eEF1A2 is a Novel Anticancer Target for the Marine Natural Product Plitidepsin.

Design, synthesis and structure-activity relationship (SAR) studies of an unusual class of non-cationic fatty amine-tripeptide conjugates as novel synthetic antimicrobial agents.

Deciphering the Chemical Basis of Fluorescence of a Selenium‐Labeled Uracil Probe when Bound at the Bacterial Ribosomal A‐Site.

Spiropyran Meets Guanine Quadruplexes: Isomerization Mechanism and DNA Binding Modes of Quinolizidine‐Substituted Spiropyran Probes.

The repertoire of iron superoxide dismutases from Leishmania infantum as targets in the search for therapeutic agents against leishmaniasis.

Molecular Basis of NDT-Mediated Activation of Nucleoside-Based Prodrugs and Application in Suicide Gene Therapy.