Works by Sánchez‐Murcia, Pedro A.

Results: 33

The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4-DRI.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60844-9

By:

Bourgeois, Benjamin;
Spreitzer, Emil;
Platero-Rochart, Daniel;
Paar, Margret;
Zhou, Qishun;
Usluer, Sinem;
de Keizer, Peter L. J.;
Burgering, Boudewijn M. T.;
Sánchez-Murcia, Pedro A.;
Madl, Tobias

Publication type:

Article

Vibrio cholerae's ToxRS bile sensing system.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.88721

By:

Gubensäk, Nina;
Sagmeister, Theo;
Buhlheller, Christoph;
Di Geronimo, Bruno;
Wagner, Gabriel E.;
Petrowitsch, Lukas;
Gräwert, Melissa A.;
Rotzinger, Markus;
Berger, Tamara M. Ismael;
Schäfer, Jan;
Usón, Isabel;
Reidl, Joachim;
Sánchez-Murcia, Pedro A.;
Zangger, Klaus;
Pavkov-Keller, Tea

Publication type:

Article

Deciphering the Chemical Basis of Fluorescence of a Selenium‐Labeled Uracil Probe when Bound at the Bacterial Ribosomal A‐Site.

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 15, p. 4927, doi. 10.1002/chem.202004818

By:

Cardenas, Gustavo;
Menger, Maximilian F. S. J.;
Ramos‐Berdullas, Nicolás;
Sánchez‐Murcia, Pedro A.

Publication type:

Article

Rücktitelbild: Unravelling the Turn‐On Fluorescence Mechanism of a Fluorescein‐Based Probe in GABAA Receptors (Angew. Chem. 30/2022).

Published in:

Angewandte Chemie, 2022, v. 134, n. 30, p. 1, doi. 10.1002/ange.202205198

By:

Singer, Nadja K.;
Sánchez‐Murcia, Pedro A.;
Ernst, Margot;
González, Leticia

Publication type:

Article

Unravelling the Turn‐On Fluorescence Mechanism of a Fluorescein‐Based Probe in GABAA Receptors.

Published in:

Angewandte Chemie, 2022, v. 134, n. 30, p. 1, doi. 10.1002/ange.202205198

By:

Singer, Nadja K.;
Sánchez‐Murcia, Pedro A.;
Ernst, Margot;
González, Leticia

Publication type:

Article

A Supramolecular Stabilizer of the 14‐3‐3ζ/ERα Protein‐Protein Interaction with a Synergistic Mode of Action.

Published in:

Angewandte Chemie, 2020, v. 132, n. 13, p. 5322, doi. 10.1002/ange.201914517

By:

Gigante, Alba;
Sijbesma, Eline;
Sánchez‐Murcia, Pedro A.;
Hu, Xiaoyu;
Bier, David;
Bäcker, Sandra;
Knauer, Shirley;
Gago, Federico;
Ottmann, Christian;
Schmuck, Carsten

Publication type:

Article

The repertoire of iron superoxide dismutases from Leishmania infantum as targets in the search for therapeutic agents against leishmaniasis.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2024, v. 39, n. 1, p. 1, doi. 10.1080/14756366.2024.2377586

By:

García-Soriano, Juan Carlos;
de Lucio, Héctor;
Elvira-Blázquez, Daniel;
Alcón-Calderón, Mercedes;
Sanz del Olmo, Natalia;
Sánchez-Murcia, Pedro A.;
Ortega, Paula;
de la Mata, Francisco Javier;
Jiménez-Ruiz, Antonio

Publication type:

Article

Structural rationale for the cross-resistance of tumor cells bearing the A399V variant of elongation factor eEF1A1 to the structurally unrelated didemnin B, ternatin, nannocystin A and ansatrienin B.

Published in:

Journal of Computer-Aided Molecular Design, 2017, v. 31, n. 10, p. 915, doi. 10.1007/s10822-017-0066-x

By:

Sánchez-Murcia, Pedro;
Cortés-Cabrera, Álvaro;
Gago, Federico

Publication type:

Article

Silyl Assistance in the Intramolecular Addition of Pyridyl Radicals onto Pyridines and Quinolines.

Published in:

European Journal of Organic Chemistry, 2016, v. 2016, n. 10, p. 1891, doi. 10.1002/ejoc.201600170

By:

Filace, Fabiana;
Sánchez ‐ Murcia, Pedro A.;
Sucunza, David;
Pérez ‐ Redondo, Adrián;
Álvarez ‐ Buílla, Julio;
Gago, Federico;
Burgos, Carolina

Publication type:

Article

PyrAtes: Modular Organic Salts with Large Stokes Shifts for Fluo‐rescence Microscopy.

Published in:

Angewandte Chemie International Edition, 2024, v. 63, n. 19, p. 1, doi. 10.1002/anie.202318127

By:

Saridakis, Iakovos;
Riomet, Margaux;
Belleza, Oliver J. V.;
Coussanes, Guilhem;
Singer, Nadja K.;
Kastner, Nina;
Xiao, Yi;
Smith, Elliot;
Tona, Veronica;
de la Torre, Aurélien;
Lopes, Eric F.;
Sánchez‐Murcia, Pedro A.;
González, Leticia;
Sitte, Harald H.;
Maulide, Nuno

Publication type:

Article

Back Cover: Unravelling the Turn‐On Fluorescence Mechanism of a Fluorescein‐Based Probe in GABAA Receptors (Angew. Chem. Int. Ed. 30/2022).

Published in:

Angewandte Chemie International Edition, 2022, v. 61, n. 30, p. 1, doi. 10.1002/anie.202205198

By:

Singer, Nadja K.;
Sánchez‐Murcia, Pedro A.;
Ernst, Margot;
González, Leticia

Publication type:

Article

Unravelling the Turn‐On Fluorescence Mechanism of a Fluorescein‐Based Probe in GABAA Receptors.

Published in:

Angewandte Chemie International Edition, 2022, v. 61, n. 30, p. 1, doi. 10.1002/anie.202205198

By:

Singer, Nadja K.;
Sánchez‐Murcia, Pedro A.;
Ernst, Margot;
González, Leticia

Publication type:

Article

A Supramolecular Stabilizer of the 14‐3‐3ζ/ERα Protein‐Protein Interaction with a Synergistic Mode of Action.

Published in:

Angewandte Chemie International Edition, 2020, v. 59, n. 13, p. 5284, doi. 10.1002/anie.201914517

By:

Gigante, Alba;
Sijbesma, Eline;
Sánchez‐Murcia, Pedro A.;
Hu, Xiaoyu;
Bier, David;
Bäcker, Sandra;
Knauer, Shirley;
Gago, Federico;
Ottmann, Christian;
Schmuck, Carsten

Publication type:

Article

Cover Feature: Ligand 1H NMR Chemical Shifts as Accurate Reporters for Protein‐Ligand Binding Interfaces in Solution (ChemPhysChem 1/2024).

Published in:

ChemPhysChem, 2024, v. 25, n. 1, p. 1, doi. 10.1002/cphc.202300636

By:

Platzer, Gerald;
Ptaszek, Aleksandra L.;
Böttcher, Jark;
Fuchs, Julian E.;
Geist, Leonhard;
Braun, Daniel;
McConnell, Darryl B.;
Konrat, Robert;
Sánchez‐Murcia, Pedro A.;
Mayer, Moriz

Publication type:

Article

Ligand 1H NMR Chemical Shifts as Accurate Reporters for Protein‐Ligand Binding Interfaces in Solution.

Published in:

ChemPhysChem, 2024, v. 25, n. 1, p. 1, doi. 10.1002/cphc.202300636

By:

Platzer, Gerald;
Ptaszek, Aleksandra L.;
Böttcher, Jark;
Fuchs, Julian E.;
Geist, Leonhard;
Braun, Daniel;
McConnell, Darryl B.;
Konrat, Robert;
Sánchez‐Murcia, Pedro A.;
Mayer, Moriz

Publication type:

Article

PyrAt‐Verbindungen: Modulare organische Salze mit großen Stokes‐Verschiebungen für die Fluoreszenzmikroskopie.

Published in:

Angewandte Chemie, 2024, v. 136, n. 19, p. 1, doi. 10.1002/ange.202318127

By:

Saridakis, Iakovos;
Riomet, Margaux;
Belleza, Oliver J. V.;
Coussanes, Guilhem;
Singer, Nadja K.;
Kastner, Nina;
Xiao, Yi;
Smith, Elliot;
Tona, Veronica;
de la Torre, Aurélien;
Lopes, Eric F.;
Sánchez‐Murcia, Pedro A.;
González, Leticia;
Sitte, Harald H.;
Maulide, Nuno

Publication type:

Article

Enzymatic β-elimination in natural product O- and C-glycoside deglycosylation.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-42750-0

By:

Bitter, Johannes;
Pfeiffer, Martin;
Borg, Annika J. E.;
Kuhlmann, Kirill;
Pavkov-Keller, Tea;
Sánchez-Murcia, Pedro A.;
Nidetzky, Bernd

Publication type:

Article

Spiropyran Meets Guanine Quadruplexes: Isomerization Mechanism and DNA Binding Modes of Quinolizidine‐Substituted Spiropyran Probes.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 57, p. 13039, doi. 10.1002/chem.202001586

By:

Avagliano, Davide;
Sánchez‐Murcia, Pedro A.;
González, Leticia

Publication type:

Article

Probing the Dimerization Interface of Leishmania infantum Trypanothione Reductase with Site-Directed Mutagenesis and Short Peptides.

Published in:

ChemBioChem, 2013, v. 14, n. 10, p. 1212, doi. 10.1002/cbic.201200744

By:

Toro, Miguel A.;
Sánchez‐Murcia, Pedro A.;
Moreno, David;
Ruiz‐Santaquiteria, Marta;
Alzate, Juan Fernando;
Negri, Ana;
Camarasa, María‐José;
Gago, Federico;
Velázquez, Sonsoles;
Jiménez‐Ruiz, Antonio

Publication type:

Article

Molecular Basis of NDT-Mediated Activation of Nucleoside-Based Prodrugs and Application in Suicide Gene Therapy.

Published in:

Biomolecules (2218-273X), 2021, v. 11, n. 1, p. 120, doi. 10.3390/biom11010120

By:

Acosta, Javier;
Pérez, Elena;
Sánchez-Murcia, Pedro A.;
Fillat, Cristina;
Fernández-Lucas, Jesús

Publication type:

Article

Structure-based domain assignment in Leishmania infantum EndoG: characterization of a pH-dependent regulatory switch and a C-terminal extension that largely dictates DNA substrate preferences.

Published in:

Nucleic Acids Research, 2017, v. 45, n. 15, p. 9030, doi. 10.1093/nar/gkx629

By:

Oliva, Cristina;
Sánchez-Murcia, Pedro A.;
Rico, Eva;
Bravo, Ana;
Menéndez, Margarita;
Gago, Federico;
Jiménez-Ruiz1, Antonio

Publication type:

Article

Unravelling the covalent binding of zampanolide and taccalonolide AJ to a minimalist representation of a human microtubule.

Published in:

Journal of Computer-Aided Molecular Design, 2019, v. 33, n. 7, p. 627, doi. 10.1007/s10822-019-00208-w

By:

Sánchez-Murcia, Pedro A.;
Mills, Alberto;
Cortés-Cabrera, Álvaro;
Gago, Federico

Publication type:

Article

Characterization of an atypical, thermostable, organic solvent- and acid-tolerant 2′-deoxyribosyltransferase from Chroococcidiopsis thermalis.

Published in:

Applied Microbiology & Biotechnology, 2018, v. 102, n. 16, p. 6947, doi. 10.1007/s00253-018-9134-y

By:

Del Arco, Jon;
Sánchez-Murcia, Pedro Alejandro;
Mancheño, José Miguel;
Gago, Federico;
Fernández-Lucas, Jesús

Publication type:

Article

Insights into the Biological Activity and Bio‐Interaction Properties of Nanoscale Imine‐Based 2D and 3D Covalent Organic Frameworks.

Published in:

Advanced Science, 2024, v. 11, n. 44, p. 1, doi. 10.1002/advs.202407391

By:

Ye, Hao;
Franco, Carlos;
Aboouf, Mostafa A.;
Thiersch, Markus;
Sevim, Semih;
Llacer‐Wintle, Joaquin;
Veciana, Andrea;
Llauradó‐Capdevila, Gemma;
Wang, Kaiyuan;
Chen, Xiang‐Zhong;
Tang, Qiao;
Matheu, Roc;
Wendel‐Garcia, Pedro D.;
Sánchez‐Murcia, Pedro A.;
Nelson, Bradley J.;
Luo, Cong;
Puigmartí‐Luis, Josep;
Pané, Salvador

Publication type:

Article

Design, synthesis and structure-activity relationship (SAR) studies of an unusual class of non-cationic fatty amine-tripeptide conjugates as novel synthetic antimicrobial agents.

Published in:

Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1428409

By:

Hernández-Ortiz, Noelia;
Sánchez-Murcia, Pedro A.;
Gil-Campillo, Celia;
Domenech, Mirian;
Lucena-Agell, Daniel;
Hortigüela, Rafael;
Velázquez, Sonsoles;
José Camarasa, María;
Bustamante, Noemí;
de Castro, Sonia;
Menéndez, Margarita

Publication type:

Article

Enzymatic Synthesis of Therapeutic Nucleosides using a Highly Versatile Purine Nucleoside 2'‐DeoxyribosylTransferase from Trypanosoma brucei.

Published in:

ChemCatChem, 2018, v. 10, n. 19, p. 4406, doi. 10.1002/cctc.201800775

By:

Pérez, Elena;
Fernández‐Lucas, Jesús;
Sánchez‐Murcia, Pedro A.;
Jordaan, Justin;
Blanco, María Dolores;
Mancheño, José Miguel;
Gago, Federico

Publication type:

Article

A new view of missense mutations in α‐mannosidosis using molecular dynamics conformational ensembles.

Published in:

Protein Science: A Publication of the Protein Society, 2025, v. 34, n. 4, p. 1, doi. 10.1002/pro.70080

By:

Mandl, Špela;
Di Geronimo, Bruno;
Alonso‐Gil, Santiago;
Grininger, Christoph;
George, Gibu;
Ferstl, Ulrika;
Herzog, Sereina Annik;
Žagrović, Bojan;
Nusshold, Christoph;
Pavkov‐Keller, Tea;
Sánchez‐Murcia, Pedro A.

Publication type:

Article

Are the Hydantoin-1,3,5-triazine 5-HT6R Ligands a Hope to a Find New Procognitive and Anti-Obesity Drug? Considerations Based on Primary In Vivo Assays and ADME-Tox Profile In Vitro.

Published in:

Molecules, 2019, v. 24, n. 24, p. 4472, doi. 10.3390/molecules24244472

By:

Lubelska, Annamaria;
Latacz, Gniewomir;
Jastrzębska-Więsek, Magdalena;
Kotańska, Magdalena;
Kurczab, Rafał;
Partyka, Anna;
Marć, Małgorzata Anna;
Wilczyńska, Daria;
Doroz-Płonka, Agata;
Łażewska, Dorota;
Wesołowska, Anna;
Kieć-Kononowicz, Katarzyna;
Handzlik, Jadwiga;
Sánchez-Murcia, Pedro A.;
Gigante, Alba;
Pérez, Víctor Sebastián

Publication type:

Article

Design, Synthesis and Biological Evaluation of New Piperazin-4-yl-(acetyl-thiazolidine-2,4-dione) Norfloxacin Analogues as Antimicrobial Agents.

Published in:

Molecules, 2019, v. 24, n. 21, p. 3959, doi. 10.3390/molecules24213959

By:

Marc, Gabriel;
Araniciu, Cătălin;
Oniga, Smaranda Dafina;
Vlase, Laurian;
Pîrnău, Adrian;
Nadăș, George Cosmin;
Novac, Cristiana Ștefania;
Matei, Ioana Adriana;
Chifiriuc, Mariana Carmen;
Măruțescu, Luminița;
Oniga, Ovidiu;
Sánchez-Murcia, Pedro A.

Publication type:

Article

Functional Characterization and Structural Analysis of NADH Oxidase Mutants from Thermus thermophilus HB27: Role of Residues 166, 174, and 194 in the Catalytic Properties and Thermostability.

Published in:

Microorganisms, 2019, v. 7, n. 11, p. 515, doi. 10.3390/microorganisms7110515

By:

Rocha-Martin, Javier;
Sánchez-Murcia, Pedro A.;
López-Gallego, Fernando;
Hidalgo, Aurelio;
Berenguer, José;
Guisan, José M.

Publication type:

Article

Modular Architecture and Unique Teichoic Acid Recognition Features of Choline-Binding Protein L (CbpL) Contributing to Pneumococcal Pathogenesis.

Published in:

Scientific Reports, 2016, p. 38094, doi. 10.1038/srep38094

By:

Gutiérrez-Fernández, Javier;
Saleh, Malek;
Alcorlo, Martín;
Gómez-Mejía, Alejandro;
Pantoja-Uceda, David;
Treviño, Miguel A.;
Voß, Franziska;
Abdullah, Mohammed R.;
Galán-Bartual, Sergio;
Seinen, Jolien;
Sánchez-Murcia, Pedro A.;
Gago, Federico;
Bruix, Marta;
Hammerschmidt, Sven;
Hermoso, Juan A.

Publication type:

Article

Translation Elongation Factor eEF1A2 is a Novel Anticancer Target for the Marine Natural Product Plitidepsin.

Published in:

Scientific Reports, 2016, p. 35100, doi. 10.1038/srep35100

By:

Losada, Alejandro;
Muñoz-Alonso, María José;
García, Carolina;
Sánchez-Murcia, Pedro A.;
Martínez-Leal, Juan Fernando;
Domínguez, Juan Manuel;
Lillo, M. Pilar;
Gago, Federico;
Galmarini, Carlos M.

Publication type:

Article

Identification of NEK3 and MOK as novel targets for lithium.

Published in:

Chemical Biology & Drug Design, 2019, v. 93, n. 5, p. 965, doi. 10.1111/cbdd.13487

By:

Bravo, Ana;
Lucio, Héctor;
Sánchez‐Murcia, Pedro A.;
Jiménez‐Ruiz, Antonio;
Petrone, Paula M.;
Gago, Federico;
Cortés Cabrera, Alvaro

Publication type:

Article

Works by Sánchez‐Murcia, Pedro A.

The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4-DRI.

Vibrio cholerae's ToxRS bile sensing system.

Deciphering the Chemical Basis of Fluorescence of a Selenium‐Labeled Uracil Probe when Bound at the Bacterial Ribosomal A‐Site.

Rücktitelbild: Unravelling the Turn‐On Fluorescence Mechanism of a Fluorescein‐Based Probe in GABA<sub>A</sub> Receptors (Angew. Chem. 30/2022).

Unravelling the Turn‐On Fluorescence Mechanism of a Fluorescein‐Based Probe in GABA<sub>A</sub> Receptors.

A Supramolecular Stabilizer of the 14‐3‐3ζ/ERα Protein‐Protein Interaction with a Synergistic Mode of Action.

The repertoire of iron superoxide dismutases from Leishmania infantum as targets in the search for therapeutic agents against leishmaniasis.

Structural rationale for the cross-resistance of tumor cells bearing the A399V variant of elongation factor eEF1A1 to the structurally unrelated didemnin B, ternatin, nannocystin A and ansatrienin B.

Silyl Assistance in the Intramolecular Addition of Pyridyl Radicals onto Pyridines and Quinolines.

PyrAtes: Modular Organic Salts with Large Stokes Shifts for Fluo‐rescence Microscopy.

Back Cover: Unravelling the Turn‐On Fluorescence Mechanism of a Fluorescein‐Based Probe in GABA<sub>A</sub> Receptors (Angew. Chem. Int. Ed. 30/2022).

Unravelling the Turn‐On Fluorescence Mechanism of a Fluorescein‐Based Probe in GABA<sub>A</sub> Receptors.

A Supramolecular Stabilizer of the 14‐3‐3ζ/ERα Protein‐Protein Interaction with a Synergistic Mode of Action.

Cover Feature: Ligand <sup>1</sup>H NMR Chemical Shifts as Accurate Reporters for Protein‐Ligand Binding Interfaces in Solution (ChemPhysChem 1/2024).

Ligand <sup>1</sup>H NMR Chemical Shifts as Accurate Reporters for Protein‐Ligand Binding Interfaces in Solution.

PyrAt‐Verbindungen: Modulare organische Salze mit großen Stokes‐Verschiebungen für die Fluoreszenzmikroskopie.

Enzymatic β-elimination in natural product O- and C-glycoside deglycosylation.

Spiropyran Meets Guanine Quadruplexes: Isomerization Mechanism and DNA Binding Modes of Quinolizidine‐Substituted Spiropyran Probes.

Probing the Dimerization Interface of Leishmania infantum Trypanothione Reductase with Site-Directed Mutagenesis and Short Peptides.

Molecular Basis of NDT-Mediated Activation of Nucleoside-Based Prodrugs and Application in Suicide Gene Therapy.

Structure-based domain assignment in Leishmania infantum EndoG: characterization of a pH-dependent regulatory switch and a C-terminal extension that largely dictates DNA substrate preferences.

Unravelling the covalent binding of zampanolide and taccalonolide AJ to a minimalist representation of a human microtubule.

Characterization of an atypical, thermostable, organic solvent- and acid-tolerant 2′-deoxyribosyltransferase from Chroococcidiopsis thermalis.

Insights into the Biological Activity and Bio‐Interaction Properties of Nanoscale Imine‐Based 2D and 3D Covalent Organic Frameworks.

Design, synthesis and structure-activity relationship (SAR) studies of an unusual class of non-cationic fatty amine-tripeptide conjugates as novel synthetic antimicrobial agents.

Enzymatic Synthesis of Therapeutic Nucleosides using a Highly Versatile Purine Nucleoside 2'‐DeoxyribosylTransferase from Trypanosoma brucei.

A new view of missense mutations in α‐mannosidosis using molecular dynamics conformational ensembles.

Are the Hydantoin-1,3,5-triazine 5-HT6R Ligands a Hope to a Find New Procognitive and Anti-Obesity Drug? Considerations Based on Primary In Vivo Assays and ADME-Tox Profile In Vitro.

Design, Synthesis and Biological Evaluation of New Piperazin-4-yl-(acetyl-thiazolidine-2,4-dione) Norfloxacin Analogues as Antimicrobial Agents.

Functional Characterization and Structural Analysis of NADH Oxidase Mutants from Thermus thermophilus HB27: Role of Residues 166, 174, and 194 in the Catalytic Properties and Thermostability.

Modular Architecture and Unique Teichoic Acid Recognition Features of Choline-Binding Protein L (CbpL) Contributing to Pneumococcal Pathogenesis.

Translation Elongation Factor eEF1A2 is a Novel Anticancer Target for the Marine Natural Product Plitidepsin.

Identification of NEK3 and MOK as novel targets for lithium.