Works by Ryazanov, Sergey

Results: 22
    1

    Targeting α-synuclein by PD03 AFFITOPE® and Anle138b rescues neurodegenerative pathology in a model of multiple system atrophy: clinical relevance.

    Published in:
    Translational Neurodegeneration, 2020, v. 9, n. 1, p. N.PAG, doi. 10.1186/s40035-020-00217-y
    By:
    • Lemos, Miguel;
    • Venezia, Serena;
    • Refolo, Violetta;
    • Heras-Garvin, Antonio;
    • Schmidhuber, Sabine;
    • Giese, Armin;
    • Leonov, Andrei;
    • Ryazanov, Sergey;
    • Griesinger, Christian;
    • Galabova, Gergana;
    • Staffler, Guenther;
    • Wenning, Gregor Karl;
    • Stefanova, Nadia
    Publication type:
    Article
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    The diphenylpyrazole compound anle138b blocks Aβ channels and rescues disease phenotypes in a mouse model for amyloid pathology.

    Published in:
    EMBO Molecular Medicine, 2018, v. 10, n. 1, p. 32, doi. 10.15252/emmm.201707825
    By:
    • Martinez Hernandez, Ana;
    • Urbanke, Hendrik;
    • Gillman, Alan L.;
    • Lee, Joon;
    • Ryazanov, Sergey;
    • Agbemenyah, Hope Y.;
    • Benito, Eva;
    • Jain, Gaurav;
    • Kaurani, Lalit;
    • Grigorian, Gayane;
    • Leonov, Andrei;
    • Rezaei‐Ghaleh, Nasrollah;
    • Wilken, Petra;
    • Arce, Fernando Teran;
    • Wagner, Jens;
    • Fuhrman, Martin;
    • Caruana, Mario;
    • Camilleri, Angelique;
    • Vassallo, Neville;
    • Zweckstetter, Markus
    Publication type:
    Article
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    Late-stage Anle138b treatment ameliorates tau pathology and metabolic decline in a mouse model of human Alzheimer's disease tau.

    Published in:
    Alzheimer's Research & Therapy, 2019, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13195-019-0522-z
    By:
    • Brendel, Matthias;
    • Deussing, Maximilian;
    • Blume, Tanja;
    • Kaiser, Lena;
    • Probst, Federico;
    • Overhoff, Felix;
    • Peters, Finn;
    • von Ungern-Sternberg, Barbara;
    • Ryazanov, Sergey;
    • Leonov, Andrei;
    • Griesinger, Christian;
    • Zwergal, Andreas;
    • Levin, Johannes;
    • Bartenstein, Peter;
    • Yakushev, Igor;
    • Cumming, Paul;
    • Boening, Guido;
    • Ziegler, Sibylle;
    • Herms, Jochen;
    • Giese, Armin
    Publication type:
    Article
    12

    Reducing tau aggregates with anle138b delays disease progression in a mouse model of tauopathies.

    Published in:
    Acta Neuropathologica, 2015, v. 130, n. 5, p. 619, doi. 10.1007/s00401-015-1483-3
    By:
    • Wagner, Jens;
    • Krauss, Sybille;
    • Shi, Song;
    • Ryazanov, Sergey;
    • Steffen, Julia;
    • Miklitz, Carolin;
    • Leonov, Andrei;
    • Kleinknecht, Alexander;
    • Göricke, Bettina;
    • Weishaupt, Jochen;
    • Weckbecker, Daniel;
    • Reiner, Anne;
    • Zinth, Wolfgang;
    • Levin, Johannes;
    • Ehninger, Dan;
    • Remy, Stefan;
    • Kretzschmar, Hans;
    • Griesinger, Christian;
    • Giese, Armin;
    • Fuhrmann, Martin
    Publication type:
    Article
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    Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's disease.

    Published in:
    Acta Neuropathologica, 2013, v. 125, n. 6, p. 795, doi. 10.1007/s00401-013-1114-9
    By:
    • Wagner, Jens;
    • Ryazanov, Sergey;
    • Leonov, Andrei;
    • Levin, Johannes;
    • Shi, Song;
    • Schmidt, Felix;
    • Prix, Catharina;
    • Pan-Montojo, Francisco;
    • Bertsch, Uwe;
    • Mitteregger-Kretzschmar, Gerda;
    • Geissen, Markus;
    • Eiden, Martin;
    • Leidel, Fabienne;
    • Hirschberger, Thomas;
    • Deeg, Andreas;
    • Krauth, Julian;
    • Zinth, Wolfgang;
    • Tavan, Paul;
    • Pilger, Jens;
    • Zweckstetter, Markus
    Publication type:
    Article
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    [11C]MODAG-001—towards a PET tracer targeting α-synuclein aggregates.

    Published in:
    European Journal of Nuclear Medicine & Molecular Imaging, 2021, v. 48, n. 6, p. 1759, doi. 10.1007/s00259-020-05133-x
    By:
    • Kuebler, Laura;
    • Buss, Sabrina;
    • Leonov, Andrei;
    • Ryazanov, Sergey;
    • Schmidt, Felix;
    • Maurer, Andreas;
    • Weckbecker, Daniel;
    • Landau, Anne M.;
    • Lillethorup, Thea P.;
    • Bleher, Daniel;
    • Saw, Ran Sing;
    • Pichler, Bernd J.;
    • Griesinger, Christian;
    • Giese, Armin;
    • Herfert, Kristina
    Publication type:
    Article
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    The clinical drug candidate anle138b binds in a cavity of lipidic α-synuclein fibrils.

    Published in:
    Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32797-w
    By:
    • Antonschmidt, Leif;
    • Matthes, Dirk;
    • Dervişoğlu, Rıza;
    • Frieg, Benedikt;
    • Dienemann, Christian;
    • Leonov, Andrei;
    • Nimerovsky, Evgeny;
    • Sant, Vrinda;
    • Ryazanov, Sergey;
    • Giese, Armin;
    • Schröder, Gunnar F.;
    • Becker, Stefan;
    • de Groot, Bert L.;
    • Griesinger, Christian;
    • Andreas, Loren B.
    Publication type:
    Article