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Proteolysis of the replication checkpoint protein Sda is necessary for the efficient initiation of sporulation after transient replication stress in Bacillus subtilis.
Published in:
Molecular Microbiology, 2006, v. 60, n. 6, p. 1490, doi. 10.1111/j.1365-2958.2006.05167.x
By:
- Ruvolo, Michael V.;
- Mach, Kathleen E.;
- Burkholder, William F.
Publication type:
Article
HDAC inhibition by SNDX-275 (Entinostat) restores expression of silenced leukemia-associated transcription factors Nur77 and Nor1 and of key pro-apoptotic proteins in AML.
Published in:
Leukemia (08876924), 2013, v. 27, n. 6, p. 1358, doi. 10.1038/leu.2012.366
By:
- Zhou, L;
- Ruvolo, V R;
- McQueen, T;
- Chen, W;
- Samudio, I J;
- Conneely, O;
- Konopleva, M;
- Andreeff, M
Publication type:
Article
Low expression of PP2A regulatory subunit B55α is associated with T308 phosphorylation of AKT and shorter complete remission duration in acute myeloid leukemia patients.
Published in:
2011
By:
- Ruvolo, P P;
- Qui, Y H;
- Coombes, K R;
- Zhang, N;
- Ruvolo, V R;
- Borthakur, G;
- Konopleva, M;
- Andreeff, M;
- Kornblau, S M
Publication type:
journal article
Roles of the Ras/Raf/MEK/ERK pathway in leukemia therapy.
Published in:
2011
By:
- Steelman, L. S.;
- Franklin, R. A.;
- Abrams, S. L.;
- Chappell, W.;
- Kempf, C. R.;
- Bäsecke, J.;
- Stivala, F.;
- Donia, M.;
- Fagone, P.;
- Nicoletti, F.;
- Libra, M.;
- Ruvolo, P.;
- Ruvolo, V.;
- Evangelisti, C.;
- Martelli, A. M.;
- McCubrey, J. A.;
- Bäsecke, J
Publication type:
journal article
Targeting the translational apparatus to improve leukemia therapy: roles of the PI3K/PTEN/Akt/mTOR pathway.
Published in:
2011
By:
- Martelli, A. M.;
- Evangelisti, C.;
- Chappell, W.;
- Abrams, S. L.;
- Bäsecke, J.;
- Stivala, F.;
- Donia, M.;
- Fagone, P.;
- Nicoletti, F.;
- Libra, M.;
- Ruvolo, V.;
- Ruvolo, P.;
- Kempf, C. R.;
- Steelman, L. S.;
- McCubrey, J. A.;
- Bäsecke, J
Publication type:
journal article
HOX expression patterns identify a common signature for favorable AML.
Published in:
2008
By:
- Andreeff, M.;
- Ruvolo, V.;
- Gadgil, S.;
- Zeng, C.;
- Coombes, K.;
- Chen, W.;
- Kornblau, S.;
- Barón, A. E.;
- Drabkin, H. A.;
- Barón, A E
Publication type:
journal article
The dual PI3 kinase/mTOR inhibitor PI-103 prevents p53 induction by Mdm2 inhibition but enhances p53-mediated mitochondrial apoptosis in p53 wild-type AML.
Published in:
2008
By:
- Kojima, K.;
- Shimanuki, M.;
- Shikami, M.;
- Samudio, I. J.;
- Ruvolo, V.;
- Corn, P.;
- Hanaoka, N.;
- Konopleva, M.;
- Andreeff, M.;
- Nakakuma, H.
Publication type:
journal article
Sorafenib induces apoptosis of AML cells via Bim-mediated activation of the intrinsic apoptotic pathway.
Published in:
2008
By:
- Zhang, W.;
- Konopleva, M.;
- Ruvolo, V. R.;
- McQueen, T.;
- Evans, R. L.;
- Bornmann, W. G.;
- McCubrey, J.;
- Cortes, J.;
- Andreeff, M.
Publication type:
journal article
Apoptosis repressor with caspase recruitment domain is regulated by MAPK/PI3K and confers drug resistance and survival advantage to AML.
Published in:
Apoptosis, 2014, v. 19, n. 4, p. 698, doi. 10.1007/s10495-013-0954-z
By:
- Mak, P.;
- Mak, D.;
- Mu, H.;
- Shi, Y.;
- Ruvolo, P.;
- Ruvolo, V.;
- Jacamo, R.;
- Burks, J.;
- Wei, W.;
- Huang, X.;
- Kornblau, S.;
- Andreeff, M.;
- Carter, B.
Publication type:
Article

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