Works by Rust, Alistair

Results: 35

Function of C/EBPδ in a regulatory circuit that discriminates between transient and persistent TLR4-induced signals.
Published in:
Nature Immunology, 2009, v. 10, n. 4, p. 437, doi. 10.1038/ni.1721
By:
- Litvak, Vladimir;
- Ramsey, Stephen A;
- Rust, Alistair G;
- Zak, Daniel E;
- Kennedy, Kathleen A;
- Lampano, Aaron E;
- Nykter, Matti;
- Shmulevich, Ilya;
- Aderem, Alan
Publication type:
Article
A lentiviral vector‐based insertional mutagenesis screen identifies mechanisms of resistance to MAPK inhibitors in melanoma.
Published in:
Pigment Cell & Melanoma Research, 2019, v. 32, n. 2, p. 332, doi. 10.1111/pcmr.12737
By:
- Ranzani, Marco;
- Alifrangis, Constantine;
- Thompson, Nicola A.;
- Rust, Alistair G.;
- Allahyar, Amin;
- Iyer, Vivek;
- Price, Stacey;
- Ellis, Peter;
- Turner, Gemma;
- de Ridder, Jeroen;
- McDermott, Ultan;
- Adams, David J.
Publication type:
Article
Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4.
Published in:
2008
By:
- Gilchrist, Mark;
- Thorsson, Vesteinn;
- Li, Bin;
- Rust, Alistair G.;
- Korb, Martin;
- Roach, Jared C.;
- Kennedy, Kathleen;
- Hai, Tsonwin;
- Bolouri, Hamid;
- Aderem, Alan
Publication type:
Correction Notice
Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4.
Published in:
Nature, 2006, v. 441, n. 7090, p. 173, doi. 10.1038/nature04768
By:
- Gilchrist, Mark;
- Thorsson, Vesteinn;
- Bin Li;
- Rust, Alistair G.;
- Korb, Martin;
- Kennedy, Kathleen;
- Tsonwin Hai;
- Bolouri, Hamid;
- Aderem, Alan
Publication type:
Article
The Mutational Concordance of Fixed Formalin Paraffin Embedded and Fresh Frozen Gastro-Oesophageal Tumours Using Whole Exome Sequencing.
Published in:
Journal of Clinical Medicine, 2021, v. 10, n. 2, p. 215, doi. 10.3390/jcm10020215
By:
- Chong, Irene Y.;
- Starling, Naureen;
- Rust, Alistair;
- Alexander, John;
- Aronson, Lauren;
- Llorca-Cardenosa, Marta;
- Chauhan, Ritika;
- Chaudry, Asif;
- Kumar, Sacheen;
- Fenwick, Kerry;
- Assiotis, Ioannis;
- Matthews, Nik;
- Begum, Ruwaida;
- Wotherspoon, Andrew;
- Terlizzo, Monica;
- Watkins, David;
- Chau, Ian;
- Lord, Christopher J.;
- Haider, Syed;
- Rao, Sheela
Publication type:
Article
A Genome-Wide Association Study for Regulators of Micronucleus Formation in Mice.
Published in:
G3: Genes | Genomes | Genetics, 2016, v. 6, n. 8, p. 2343, doi. 10.1534/g3.116.030767
By:
- McIntyre, Rebecca E.;
- Nicod, Jérôme;
- Robles-Espinoza, Carla Daniela;
- Maciejowski, John;
- Na Cai;
- Hill, Jennifer;
- Verstraten, Ruth;
- Iyer, Vivek;
- Rust, Alistair G.;
- Balmus, Gabriel;
- Mott, Richard;
- Flint, Jonathan;
- Adams, David J.
Publication type:
Article
The mutational landscapes of genetic and chemical models of Kras-driven lung cancer.
Published in:
Nature, 2015, v. 517, n. 7535, p. 489, doi. 10.1038/nature13898
By:
- Westcott, Peter M. K.;
- Halliwill, Kyle D.;
- To, Minh D.;
- Rashid, Mamunur;
- Rust, Alistair G.;
- Keane, Thomas M.;
- Delrosario, Reyno;
- Jen, Kuang-Yu;
- Gurley, Kay E.;
- Kemp, Christopher J.;
- Fredlund, Erik;
- Quigley, David A.;
- Adams, David J.;
- Balmain, Allan
Publication type:
Article
Corrigendum: The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma.
Published in:
2013
By:
- Pérez-Mancera, Pedro A.;
- Rust, Alistair G.;
- van der Weyden, Louise;
- Kristiansen, Glen;
- Li, Allen;
- Sarver, Aaron L.;
- Silverstein, Kevin A. T.;
- Grützmann, Robert;
- Aust, Daniela;
- Rümmele, Petra;
- Knösel, Thomas;
- Herd, Colin;
- Stemple, Derek L.;
- Kettleborough, Ross;
- Brosnan, Jacqueline A.;
- Li, Ang;
- Morgan, Richard;
- Knight, Spencer;
- Yu, Jun;
- Stegeman, Shane
Publication type:
Erratum
A FOXO3-IRF7 gene regulatory circuit limits inflammatory sequelae of antiviral responses.
Published in:
Nature, 2012, v. 490, n. 7420, p. 421, doi. 10.1038/nature11428
By:
- Litvak, Vladimir;
- Ratushny, Alexander V.;
- Lampano, Aaron E.;
- Schmitz, Frank;
- Huang, Albert C.;
- Raman, Ayush;
- Rust, Alistair G.;
- Bergthaler, Andreas;
- Aitchison, John D.;
- Aderem, Alan
Publication type:
Article
The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma.
Published in:
Nature, 2012, v. 486, n. 7402, p. 266, doi. 10.1038/nature11114
By:
- Pérez-Mancera, Pedro A.;
- Rust, Alistair G.;
- van der Weyden, Louise;
- Kristiansen, Glen;
- Li, Allen;
- Sarver, Aaron L.;
- Silverstein, Kevin A. T.;
- Grützmann, Robert;
- Aust, Daniela;
- Rümmele, Petra;
- Knösel, Thomas;
- Herd, Colin;
- Stemple, Derek L.;
- Kettleborough, Ross;
- Brosnan, Jacqueline A.;
- Li, Ang;
- Morgan, Richard;
- Knight, Spencer;
- Yu, Jun;
- Stegeman, Shane
Publication type:
Article
Nuclear receptor binding protein 1 regulates intestinal progenitor cell homeostasis and tumour formation.
Published in:
EMBO Journal, 2012, v. 31, n. 11, p. 2486, doi. 10.1038/emboj.2012.91
By:
- Wilson, Catherine H;
- Crombie, Catriona;
- van der Weyden, Louise;
- Poulogiannis, George;
- Rust, Alistair G;
- Pardo, Mercedes;
- Gracia, Tannia;
- Yu, Lu;
- Choudhary, Jyoti;
- Poulin, Gino B;
- McIntyre, Rebecca E;
- Winton, Douglas J;
- March, H Nikki;
- Arends, Mark J;
- Fraser, Andrew G;
- Adams, David J
Publication type:
Article
TRANSCRIPTION BINDING SITE PREDICTION USING MARKOV MODELS.
Published in:
Journal of Bioinformatics & Computational Biology, 2006, v. 4, n. 2, p. 425, doi. 10.1142/S0219720006001813
By:
- Abnizova, Irina;
- Rust, Alistair G.;
- Robinson, Mark;
- Te Boekhorst, Rene;
- Gilks, Walter R.
Publication type:
Article
Somatic drivers of B-ALL in a model of ETV6-RUNX1; Pax5+/- leukemia.
Published in:
BMC Cancer, 2015, v. 15, n. 1, p. 1, doi. 10.1186/s12885-015-1586-1
By:
- van der Weyden, Louise;
- Giotopoulos, George;
- Kim Wong;
- Rust, Alistair G.;
- Robles-Espinoza, Carla Daniela;
- Hikari Osaki;
- Huntly, Brian J.;
- Adams, David J.
Publication type:
Article
Somatic drivers of B-ALL in a model of ETV6-RUNX1; Pax5(+/-) leukemia.
Published in:
2015
By:
- van der Weyden, Louise;
- Giotopoulos, George;
- Wong, Kim;
- Rust, Alistair G;
- Robles-Espinoza, Carla Daniela;
- Osaki, Hikari;
- Huntly, Brian J;
- Adams, David J
Publication type:
journal article
Uncovering a Macrophage Transcriptional Program by Integrating Evidence from Motif Scanning and Expression Dynamics.
Published in:
PLoS Computational Biology, 2008, v. 4, n. 3, p. 1, doi. 10.1371/journal.pcbi.1000021
By:
- Ramsey, Stephen A.;
- Klemm, Sandy L.;
- Zak, Daniel E.;
- Kennedy, Kathleen A.;
- Thorsson, Vesteinn;
- Bin Li;
- Gilchrist, Mark;
- Gold, Elizabeth S.;
- Johnson, Carrie D.;
- Litvak, Vladimir;
- Navarro, Garnet;
- Roach, Jared C.;
- Rosenberger, Carrie M.;
- Rust, Alistair G.;
- Yudkovsky, Natalya;
- Aderem, Alan;
- Shmulevich, Ilya
Publication type:
Article
Capture Hi-C identifies putative target genes at 33 breast cancer risk loci.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-03411-9
By:
- Baxter, Joseph S.;
- Leavy, Olivia C.;
- Dryden, Nicola H.;
- Maguire, Sarah;
- Johnson, Nichola;
- Fedele, Vita;
- Simigdala, Nikiana;
- Martin, Lesley-Ann;
- Andrews, Simon;
- Wingett, Steven W.;
- Assiotis, Ioannis;
- Fenwick, Kerry;
- Chauhan, Ritika;
- Rust, Alistair G.;
- Orr, Nick;
- Dudbridge, Frank;
- Haider, Syed;
- Fletcher, Olivia
Publication type:
Article
The Innate Immune Database (IIDB).
Published in:
BMC Immunology, 2008, v. 9, p. 1, doi. 10.1186/1471-2172-9-7
By:
- Korb, Martin;
- Rust, Alistair G.;
- Thorsson, Vesteinn;
- Battail, Christophe;
- Bin Li;
- Daehee Hwang;
- Kennedy, Kathleen A.;
- Roach, Jared C.;
- Rosenberger, Carrie M.;
- Gilchrist, Mark;
- Zak, Daniel;
- Johnson, Carrie;
- Marzolf, Bruz;
- Aderem, Alan;
- Shmulevich, Ilya;
- Bolouri, Hamid
Publication type:
Article
Chromatin Landscapes of Retroviral and Transposon Integration Profiles.
Published in:
PLoS Genetics, 2014, v. 10, n. 4, p. 1, doi. 10.1371/journal.pgen.1004250
By:
- de Jong, Johann;
- Akhtar, Waseem;
- Badhai, Jitendra;
- Rust, Alistair G.;
- Rad, Roland;
- Hilkens, John;
- Berns, Anton;
- van Lohuizen, Maarten;
- Wessels, Lodewyk F. A.;
- de Ridder, Jeroen
Publication type:
Article
Insertional Mutagenesis and Deep Profiling Reveals Gene Hierarchies and a Myc/p53-Dependent Bottleneck in Lymphomagenesis.
Published in:
PLoS Genetics, 2014, v. 10, n. 2, p. 1, doi. 10.1371/journal.pgen.1004167
By:
- Huser, Camille A.;
- Gilroy, Kathryn L.;
- de Ridder, Jeroen;
- Kilbey, Anna;
- Borland, Gillian;
- Mackay, Nancy;
- Jenkins, Alma;
- Bell, Margaret;
- Herzyk, Pawel;
- van der Weyden, Louise;
- Adams, David J.;
- Rust, Alistair G.;
- Cameron, Ewan;
- Neil, James C.
Publication type:
Article
Transposon mutagenesis identifies genetic drivers of BrafV600E melanoma.
Published in:
Nature Genetics, 2015, v. 47, n. 5, p. 486, doi. 10.1038/ng.3275
By:
- Mann, Michael B;
- Copeland, Neal G;
- Jenkins, Nancy A;
- Black, Michael A;
- Jones, Devin J;
- Newberg, Justin Y;
- Ward, Jerrold M;
- Yew, Christopher Chin Kuan;
- Dupuy, Adam J;
- Rust, Alistair G;
- Bosenberg, Marcus W;
- McMahon, Martin;
- Print, Cristin G
Publication type:
Article
Transposon mutagenesis identifies genes and evolutionary forces driving gastrointestinal tract tumor progression.
Published in:
Nature Genetics, 2015, v. 47, n. 2, p. 142, doi. 10.1038/ng.3175
By:
- Takeda, Haruna;
- Yew, Christopher Chin Kuan;
- Mann, Michael B;
- Jenkins, Nancy A;
- Rust, Alistair G;
- Adams, David J;
- Copeland, Neal G;
- Koso, Hideto;
- Wei, Zhubo;
- Ward, Jerrold M
Publication type:
Article
Inactivating CUX1 mutations promote tumorigenesis.
Published in:
Nature Genetics, 2014, v. 46, n. 1, p. 33, doi. 10.1038/ng.2846
By:
- Wong, Chi C;
- Martincorena, Inigo;
- Rust, Alistair G;
- Rashid, Mamunur;
- Alifrangis, Constantine;
- Alexandrov, Ludmil B;
- Tiffen, Jessamy C;
- Kober, Christina;
- Green, Anthony R;
- Massie, Charles E;
- Nangalia, Jyoti;
- Lempidaki, Stella;
- Döhner, Hartmut;
- Döhner, Konstanze;
- Bray, Sarah J;
- McDermott, Ultan;
- Papaemmanuil, Elli;
- Campbell, Peter J;
- Adams, David J
Publication type:
Article
Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse model.
Published in:
Nature Genetics, 2014, v. 46, n. 1, p. 24, doi. 10.1038/ng.2847
By:
- Bard-Chapeau, Emilie A;
- Nguyen, Anh-Tuan;
- Rust, Alistair G;
- Sayadi, Ahmed;
- Lee, Philip;
- Chua, Belinda Q;
- New, Lee-Sun;
- de Jong, Johann;
- Ward, Jerrold M;
- Chin, Christopher K Y;
- Chew, Valerie;
- Toh, Han Chong;
- Abastado, Jean-Pierre;
- Benoukraf, Touati;
- Soong, Richie;
- Bard, Frederic A;
- Dupuy, Adam J;
- Johnson, Randy L;
- Radda, George K;
- Chan, Eric Chun Yong
Publication type:
Article
Insertional mutagenesis identifies multiple networks of cooperating genes driving intestinal tumorigenesis.
Published in:
Nature Genetics, 2011, v. 43, n. 12, p. 1202, doi. 10.1038/ng.990
By:
- March, H Nikki;
- Rust, Alistair G;
- Wright, Nicholas A;
- ten Hoeve, Jelle;
- de Ridder, Jeroen;
- Eldridge, Matthew;
- van der Weyden, Louise;
- Berns, Anton;
- Gadiot, Jules;
- Uren, Anthony;
- Kemp, Richard;
- Arends, Mark J;
- Wessels, Lodewyk F A;
- Winton, Douglas J;
- Adams, David J
Publication type:
Article
A Data Integration Framework for Prediction of Transcription Factor Targets.
Published in:
Annals of the New York Academy of Sciences, 2009, v. 1158, p. 205, doi. 10.1111/j.1749-6632.2008.03758.x
By:
- Nykter, Matti;
- Lähdesmäki, Harri;
- Rust, Alistair;
- Thorsson, Vesteinn;
- Shmulevich, Ilya
Publication type:
Article
Cake: a bioinformatics pipeline for the integrated analysis of somatic variants in cancer genomes.
Published in:
Bioinformatics, 2013, v. 29, n. 17, p. 2208, doi. 10.1093/bioinformatics/btt371
By:
- Rashid, Mamunur;
- Robles-Espinoza, Carla Daniela;
- Rust, Alistair G.;
- Adams, David J.
Publication type:
Article
Generation of the Sotos syndrome deletion in mice.
Published in:
Mammalian Genome, 2012, v. 23, n. 11/12, p. 749, doi. 10.1007/s00335-012-9416-0
By:
- Migdalska, Anna;
- Weyden, Louise;
- Ismail, Ozama;
- Rust, Alistair;
- Rashid, Mamunur;
- White, Jacqueline;
- Sánchez-Andrade, Gabriela;
- Lupski, James;
- Logan, Darren;
- Arends, Mark;
- Adams, David
Publication type:
Article
Integrating genomic binding site predictions using real-valued meta classifiers.
Published in:
Neural Computing & Applications, 2009, v. 18, n. 6, p. 577, doi. 10.1007/s00521-008-0204-4
By:
- Yi Sun;
- Robinson, Mark;
- Adams, Rod;
- Te Boekhorst, Rene;
- Rust, Alistair G.;
- Davey, Neil
Publication type:
Article
FFPE breast tumour blocks provide reliable sources of both germline and malignant DNA for investigation of genetic determinants of individual tumour responses to treatment.
Published in:
Breast Cancer Research & Treatment, 2018, v. 170, n. 3, p. 573, doi. 10.1007/s10549-018-4798-7
By:
- Wilkins, Anna;
- Chauhan, Ritika;
- Rust, Alistair;
- Pearson, Alex;
- Daley, Frances;
- Manodoro, Floriana;
- Fenwick, Kerry;
- Bliss, Judith;
- Yarnold, John;
- Somaiah, Navita
Publication type:
Article
Optimised ARID1A immunohistochemistry is an accurate predictor of ARID1A mutational status in gynaecological cancers.
Published in:
Journal of Pathology: Clinical Research, 2018, v. 4, n. 3, p. 154, doi. 10.1002/cjp2.103
By:
- Khalique, Saira;
- Naidoo, Kalnisha;
- Attygalle, Ayoma D.;
- Kriplani, Divya;
- Daley, Frances;
- Lowe, Anne;
- Campbell, James;
- Jones, Thomas;
- Hubank, Michael;
- Fenwick, Kerry;
- Matthews, Nicholas;
- Rust, Alistair G.;
- Lord, Christopher J.;
- Banerjee, Susana;
- Natrajan, Rachael
Publication type:
Article
Probabilistic Inference of Transcription Factor Binding from Multiple Data Sources.
Published in:
PLoS ONE, 2008, v. 3, n. 3, p. 1, doi. 10.1371/journal.pone.0001820
By:
- Lähdesmäki, Harri;
- Rust, Alistair G.;
- Shmulevich, Ilya
Publication type:
Article
Analyzing tumor heterogeneity and driver genes in single myeloid leukemia cells with SBCapSeq.
Published in:
Nature Biotechnology, 2016, v. 34, n. 9, p. 962, doi. 10.1038/nbt.3637
By:
- Mann, Karen M;
- Newberg, Justin Y;
- Black, Michael A;
- Jones, Devin J;
- Amaya-Manzanares, Felipe;
- Guzman-Rojas, Liliana;
- Kodama, Takahiro;
- Ward, Jerrold M;
- Rust, Alistair G;
- van der Weyden, Louise;
- Yew, Christopher Chin Kuan;
- Waters, Jill L;
- Leung, Marco L;
- Rogers, Keith;
- Rogers, Susan M;
- McNoe, Leslie A;
- Selvanesan, Luxmanan;
- Navin, Nicholas;
- Jenkins, Nancy A;
- Copeland, Neal G
Publication type:
Article
Adenoma development in familial adenomatous polyposis and MUTYH-associated polyposis: somatic landscape and driver genes.
Published in:
Journal of Pathology, 2016, v. 238, n. 1, p. 98, doi. 10.1002/path.4643
By:
- Rashid, Mamunur;
- Fischer, Andrej;
- Wilson, Cathy H;
- Tiffen, Jessamy;
- Rust, Alistair G;
- Stevens, Philip;
- Idziaszczyk, Shelley;
- Maynard, Julie;
- Williams, Geraint T;
- Mustonen, Ville;
- Sampson, Julian R;
- Adams, David J
Publication type:
Article
Acute sensitivity of the oral mucosa to oncogenic K-ras.
Published in:
Journal of Pathology, 2011, v. 224, n. 1, p. 22, doi. 10.1002/path.2853
By:
- van der Weyden, Louise;
- Alcolea, Maria P;
- Jones, Philip H;
- Rust, Alistair G;
- Arends, Mark J;
- Adams, David J
Publication type:
Article
Increased tumorigenesis associated with loss of the tumor suppressor gene Cadm1.
Published in:
Molecular Cancer, 2012, v. 11, n. 1, p. 29, doi. 10.1186/1476-4598-11-29
By:
- van der Weyden, Louise;
- Arends, Mark J.;
- Rust, Alistair G.;
- Poulogiannis, George;
- McIntyre, Rebecca E.;
- Adams, David J.
Publication type:
Article

Works by Rust, Alistair

Function of C/EBPδ in a regulatory circuit that discriminates between transient and persistent TLR4-induced signals.

A lentiviral vector‐based insertional mutagenesis screen identifies mechanisms of resistance to MAPK inhibitors in melanoma.

Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4.

Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4.

The Mutational Concordance of Fixed Formalin Paraffin Embedded and Fresh Frozen Gastro-Oesophageal Tumours Using Whole Exome Sequencing.

A Genome-Wide Association Study for Regulators of Micronucleus Formation in Mice.

The mutational landscapes of genetic and chemical models of Kras-driven lung cancer.

Corrigendum: The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma.

A FOXO3-IRF7 gene regulatory circuit limits inflammatory sequelae of antiviral responses.

The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma.

Nuclear receptor binding protein 1 regulates intestinal progenitor cell homeostasis and tumour formation.

TRANSCRIPTION BINDING SITE PREDICTION USING MARKOV MODELS.

Somatic drivers of B-ALL in a model of ETV6-RUNX1; Pax5<sup>+/-</sup> leukemia.

Somatic drivers of B-ALL in a model of ETV6-RUNX1; Pax5(+/-) leukemia.

Uncovering a Macrophage Transcriptional Program by Integrating Evidence from Motif Scanning and Expression Dynamics.

Capture Hi-C identifies putative target genes at 33 breast cancer risk loci.

The Innate Immune Database (IIDB).

Chromatin Landscapes of Retroviral and Transposon Integration Profiles.

Insertional Mutagenesis and Deep Profiling Reveals Gene Hierarchies and a <i>Myc/p53</i>-Dependent Bottleneck in Lymphomagenesis.

Transposon mutagenesis identifies genetic drivers of Braf<sup>V600E</sup> melanoma.

Transposon mutagenesis identifies genes and evolutionary forces driving gastrointestinal tract tumor progression.

Inactivating CUX1 mutations promote tumorigenesis.

Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse model.

Insertional mutagenesis identifies multiple networks of cooperating genes driving intestinal tumorigenesis.

A Data Integration Framework for Prediction of Transcription Factor Targets.

Cake: a bioinformatics pipeline for the integrated analysis of somatic variants in cancer genomes.

Generation of the Sotos syndrome deletion in mice.

Integrating genomic binding site predictions using real-valued meta classifiers.

FFPE breast tumour blocks provide reliable sources of both germline and malignant DNA for investigation of genetic determinants of individual tumour responses to treatment.

Optimised ARID1A immunohistochemistry is an accurate predictor of ARID1A mutational status in gynaecological cancers.

Probabilistic Inference of Transcription Factor Binding from Multiple Data Sources.

Analyzing tumor heterogeneity and driver genes in single myeloid leukemia cells with SBCapSeq.

Adenoma development in familial adenomatous polyposis and MUTYH-associated polyposis: somatic landscape and driver genes.

Acute sensitivity of the oral mucosa to oncogenic K-ras.

Increased tumorigenesis associated with loss of the tumor suppressor gene Cadm1.