Works matching AU Rust, Alistair

Results: 35

Function of C/EBPδ in a regulatory circuit that discriminates between transient and persistent TLR4-induced signals.

Published in:

Nature Immunology, 2009, v. 10, n. 4, p. 437, doi. 10.1038/ni.1721

By:

Litvak, Vladimir;
Ramsey, Stephen A;
Rust, Alistair G;
Zak, Daniel E;
Kennedy, Kathleen A;
Lampano, Aaron E;
Nykter, Matti;
Shmulevich, Ilya;
Aderem, Alan

Publication type:

Article

The Mutational Concordance of Fixed Formalin Paraffin Embedded and Fresh Frozen Gastro-Oesophageal Tumours Using Whole Exome Sequencing.

Published in:

Journal of Clinical Medicine, 2021, v. 10, n. 2, p. 215, doi. 10.3390/jcm10020215

By:

Chong, Irene Y.;
Starling, Naureen;
Rust, Alistair;
Alexander, John;
Aronson, Lauren;
Llorca-Cardenosa, Marta;
Chauhan, Ritika;
Chaudry, Asif;
Kumar, Sacheen;
Fenwick, Kerry;
Assiotis, Ioannis;
Matthews, Nik;
Begum, Ruwaida;
Wotherspoon, Andrew;
Terlizzo, Monica;
Watkins, David;
Chau, Ian;
Lord, Christopher J.;
Haider, Syed;
Rao, Sheela

Publication type:

Article

A lentiviral vector‐based insertional mutagenesis screen identifies mechanisms of resistance to MAPK inhibitors in melanoma.

Published in:

Pigment Cell & Melanoma Research, 2019, v. 32, n. 2, p. 332, doi. 10.1111/pcmr.12737

By:

Ranzani, Marco;
Alifrangis, Constantine;
Thompson, Nicola A.;
Rust, Alistair G.;
Allahyar, Amin;
Iyer, Vivek;
Price, Stacey;
Ellis, Peter;
Turner, Gemma;
de Ridder, Jeroen;
McDermott, Ultan;
Adams, David J.

Publication type:

Article

Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4.

Published in:

2008

By:

Gilchrist, Mark;
Thorsson, Vesteinn;
Li, Bin;
Rust, Alistair G.;
Korb, Martin;
Roach, Jared C.;
Kennedy, Kathleen;
Hai, Tsonwin;
Bolouri, Hamid;
Aderem, Alan

Publication type:

Correction Notice

Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4.

Published in:

Nature, 2006, v. 441, n. 7090, p. 173, doi. 10.1038/nature04768

By:

Gilchrist, Mark;
Thorsson, Vesteinn;
Bin Li;
Rust, Alistair G.;
Korb, Martin;
Kennedy, Kathleen;
Tsonwin Hai;
Bolouri, Hamid;
Aderem, Alan

Publication type:

Article

Insertional mutagenesis identifies multiple networks of cooperating genes driving intestinal tumorigenesis.

Published in:

Nature Genetics, 2011, v. 43, n. 12, p. 1202, doi. 10.1038/ng.990

By:

March, H Nikki;
Rust, Alistair G;
Wright, Nicholas A;
ten Hoeve, Jelle;
de Ridder, Jeroen;
Eldridge, Matthew;
van der Weyden, Louise;
Berns, Anton;
Gadiot, Jules;
Uren, Anthony;
Kemp, Richard;
Arends, Mark J;
Wessels, Lodewyk F A;
Winton, Douglas J;
Adams, David J

Publication type:

Article

Chromatin Landscapes of Retroviral and Transposon Integration Profiles.

Published in:

PLoS Genetics, 2014, v. 10, n. 4, p. 1, doi. 10.1371/journal.pgen.1004250

By:

de Jong, Johann;
Akhtar, Waseem;
Badhai, Jitendra;
Rust, Alistair G.;
Rad, Roland;
Hilkens, John;
Berns, Anton;
van Lohuizen, Maarten;
Wessels, Lodewyk F. A.;
de Ridder, Jeroen

Publication type:

Article

Insertional Mutagenesis and Deep Profiling Reveals Gene Hierarchies and a Myc/p53-Dependent Bottleneck in Lymphomagenesis.

Published in:

PLoS Genetics, 2014, v. 10, n. 2, p. 1, doi. 10.1371/journal.pgen.1004167

By:

Huser, Camille A.;
Gilroy, Kathryn L.;
de Ridder, Jeroen;
Kilbey, Anna;
Borland, Gillian;
Mackay, Nancy;
Jenkins, Alma;
Bell, Margaret;
Herzyk, Pawel;
van der Weyden, Louise;
Adams, David J.;
Rust, Alistair G.;
Cameron, Ewan;
Neil, James C.

Publication type:

Article

Optimised ARID1A immunohistochemistry is an accurate predictor of ARID1A mutational status in gynaecological cancers.

Published in:

Journal of Pathology: Clinical Research, 2018, v. 4, n. 3, p. 154, doi. 10.1002/cjp2.103

By:

Khalique, Saira;
Naidoo, Kalnisha;
Attygalle, Ayoma D.;
Kriplani, Divya;
Daley, Frances;
Lowe, Anne;
Campbell, James;
Jones, Thomas;
Hubank, Michael;
Fenwick, Kerry;
Matthews, Nicholas;
Rust, Alistair G.;
Lord, Christopher J.;
Banerjee, Susana;
Natrajan, Rachael

Publication type:

Article

A Genome-Wide Association Study for Regulators of Micronucleus Formation in Mice.

Published in:

G3: Genes | Genomes | Genetics, 2016, v. 6, n. 8, p. 2343, doi. 10.1534/g3.116.030767

By:

McIntyre, Rebecca E.;
Nicod, Jérôme;
Robles-Espinoza, Carla Daniela;
Maciejowski, John;
Na Cai;
Hill, Jennifer;
Verstraten, Ruth;
Iyer, Vivek;
Rust, Alistair G.;
Balmus, Gabriel;
Mott, Richard;
Flint, Jonathan;
Adams, David J.

Publication type:

Article

Transposon mutagenesis identifies genetic drivers of BrafV600E melanoma.

Published in:

Nature Genetics, 2015, v. 47, n. 5, p. 486, doi. 10.1038/ng.3275

By:

Mann, Michael B;
Copeland, Neal G;
Jenkins, Nancy A;
Black, Michael A;
Jones, Devin J;
Newberg, Justin Y;
Ward, Jerrold M;
Yew, Christopher Chin Kuan;
Dupuy, Adam J;
Rust, Alistair G;
Bosenberg, Marcus W;
McMahon, Martin;
Print, Cristin G

Publication type:

Article

Transposon mutagenesis identifies genes and evolutionary forces driving gastrointestinal tract tumor progression.

Published in:

Nature Genetics, 2015, v. 47, n. 2, p. 142, doi. 10.1038/ng.3175

By:

Takeda, Haruna;
Yew, Christopher Chin Kuan;
Mann, Michael B;
Jenkins, Nancy A;
Rust, Alistair G;
Adams, David J;
Copeland, Neal G;
Koso, Hideto;
Wei, Zhubo;
Ward, Jerrold M

Publication type:

Article

Inactivating CUX1 mutations promote tumorigenesis.

Published in:

Nature Genetics, 2014, v. 46, n. 1, p. 33, doi. 10.1038/ng.2846

By:

Wong, Chi C;
Martincorena, Inigo;
Rust, Alistair G;
Rashid, Mamunur;
Alifrangis, Constantine;
Alexandrov, Ludmil B;
Tiffen, Jessamy C;
Kober, Christina;
Green, Anthony R;
Massie, Charles E;
Nangalia, Jyoti;
Lempidaki, Stella;
Döhner, Hartmut;
Döhner, Konstanze;
Bray, Sarah J;
McDermott, Ultan;
Papaemmanuil, Elli;
Campbell, Peter J;
Adams, David J

Publication type:

Article

Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse model.

Published in:

Nature Genetics, 2014, v. 46, n. 1, p. 24, doi. 10.1038/ng.2847

By:

Bard-Chapeau, Emilie A;
Nguyen, Anh-Tuan;
Rust, Alistair G;
Sayadi, Ahmed;
Lee, Philip;
Chua, Belinda Q;
New, Lee-Sun;
de Jong, Johann;
Ward, Jerrold M;
Chin, Christopher K Y;
Chew, Valerie;
Toh, Han Chong;
Abastado, Jean-Pierre;
Benoukraf, Touati;
Soong, Richie;
Bard, Frederic A;
Dupuy, Adam J;
Johnson, Randy L;
Radda, George K;
Chan, Eric Chun Yong

Publication type:

Article

Increased tumorigenesis associated with loss of the tumor suppressor gene Cadm1.

Published in:

Molecular Cancer, 2012, v. 11, n. 1, p. 29, doi. 10.1186/1476-4598-11-29

By:

van der Weyden, Louise;
Arends, Mark J.;
Rust, Alistair G.;
Poulogiannis, George;
McIntyre, Rebecca E.;
Adams, David J.

Publication type:

Article

Cake: a bioinformatics pipeline for the integrated analysis of somatic variants in cancer genomes.

Published in:

Bioinformatics, 2013, v. 29, n. 17, p. 2208, doi. 10.1093/bioinformatics/btt371

By:

Rashid, Mamunur;
Robles-Espinoza, Carla Daniela;
Rust, Alistair G.;
Adams, David J.

Publication type:

Article

Integrating genomic binding site predictions using real-valued meta classifiers.

Published in:

Neural Computing & Applications, 2009, v. 18, n. 6, p. 577, doi. 10.1007/s00521-008-0204-4

By:

Yi Sun;
Robinson, Mark;
Adams, Rod;
Te Boekhorst, Rene;
Rust, Alistair G.;
Davey, Neil

Publication type:

Article

The Innate Immune Database (IIDB).

Published in:

BMC Immunology, 2008, v. 9, p. 1, doi. 10.1186/1471-2172-9-7

By:

Korb, Martin;
Rust, Alistair G.;
Thorsson, Vesteinn;
Battail, Christophe;
Bin Li;
Daehee Hwang;
Kennedy, Kathleen A.;
Roach, Jared C.;
Rosenberger, Carrie M.;
Gilchrist, Mark;
Zak, Daniel;
Johnson, Carrie;
Marzolf, Bruz;
Aderem, Alan;
Shmulevich, Ilya;
Bolouri, Hamid

Publication type:

Article

Uncovering a Macrophage Transcriptional Program by Integrating Evidence from Motif Scanning and Expression Dynamics.

Published in:

PLoS Computational Biology, 2008, v. 4, n. 3, p. 1, doi. 10.1371/journal.pcbi.1000021

By:

Ramsey, Stephen A.;
Klemm, Sandy L.;
Zak, Daniel E.;
Kennedy, Kathleen A.;
Thorsson, Vesteinn;
Bin Li;
Gilchrist, Mark;
Gold, Elizabeth S.;
Johnson, Carrie D.;
Litvak, Vladimir;
Navarro, Garnet;
Roach, Jared C.;
Rosenberger, Carrie M.;
Rust, Alistair G.;
Yudkovsky, Natalya;
Aderem, Alan;
Shmulevich, Ilya

Publication type:

Article

A Data Integration Framework for Prediction of Transcription Factor Targets.

Published in:

Annals of the New York Academy of Sciences, 2009, v. 1158, p. 205, doi. 10.1111/j.1749-6632.2008.03758.x

By:

Nykter, Matti;
Lähdesmäki, Harri;
Rust, Alistair;
Thorsson, Vesteinn;
Shmulevich, Ilya

Publication type:

Article

TRANSCRIPTION BINDING SITE PREDICTION USING MARKOV MODELS.

Published in:

Journal of Bioinformatics & Computational Biology, 2006, v. 4, n. 2, p. 425, doi. 10.1142/S0219720006001813

By:

Abnizova, Irina;
Rust, Alistair G.;
Robinson, Mark;
Te Boekhorst, Rene;
Gilks, Walter R.

Publication type:

Article

Capture Hi-C identifies putative target genes at 33 breast cancer risk loci.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-03411-9

By:

Baxter, Joseph S.;
Leavy, Olivia C.;
Dryden, Nicola H.;
Maguire, Sarah;
Johnson, Nichola;
Fedele, Vita;
Simigdala, Nikiana;
Martin, Lesley-Ann;
Andrews, Simon;
Wingett, Steven W.;
Assiotis, Ioannis;
Fenwick, Kerry;
Chauhan, Ritika;
Rust, Alistair G.;
Orr, Nick;
Dudbridge, Frank;
Haider, Syed;
Fletcher, Olivia

Publication type:

Article

Nuclear receptor binding protein 1 regulates intestinal progenitor cell homeostasis and tumour formation.

Published in:

EMBO Journal, 2012, v. 31, n. 11, p. 2486, doi. 10.1038/emboj.2012.91

By:

Wilson, Catherine H;
Crombie, Catriona;
van der Weyden, Louise;
Poulogiannis, George;
Rust, Alistair G;
Pardo, Mercedes;
Gracia, Tannia;
Yu, Lu;
Choudhary, Jyoti;
Poulin, Gino B;
McIntyre, Rebecca E;
Winton, Douglas J;
March, H Nikki;
Arends, Mark J;
Fraser, Andrew G;
Adams, David J

Publication type:

Article

Probabilistic Inference of Transcription Factor Binding from Multiple Data Sources.

Published in:

PLoS ONE, 2008, v. 3, n. 3, p. 1, doi. 10.1371/journal.pone.0001820

By:

Lähdesmäki, Harri;
Rust, Alistair G.;
Shmulevich, Ilya

Publication type:

Article

FFPE breast tumour blocks provide reliable sources of both germline and malignant DNA for investigation of genetic determinants of individual tumour responses to treatment.

Published in:

Breast Cancer Research & Treatment, 2018, v. 170, n. 3, p. 573, doi. 10.1007/s10549-018-4798-7

By:

Wilkins, Anna;
Chauhan, Ritika;
Rust, Alistair;
Pearson, Alex;
Daley, Frances;
Manodoro, Floriana;
Fenwick, Kerry;
Bliss, Judith;
Yarnold, John;
Somaiah, Navita

Publication type:

Article

Corrigendum: The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma.

Published in:

2013

By:

Pérez-Mancera, Pedro A.;
Rust, Alistair G.;
van der Weyden, Louise;
Kristiansen, Glen;
Li, Allen;
Sarver, Aaron L.;
Silverstein, Kevin A. T.;
Grützmann, Robert;
Aust, Daniela;
Rümmele, Petra;
Knösel, Thomas;
Herd, Colin;
Stemple, Derek L.;
Kettleborough, Ross;
Brosnan, Jacqueline A.;
Li, Ang;
Morgan, Richard;
Knight, Spencer;
Yu, Jun;
Stegeman, Shane

Publication type:

Erratum

A FOXO3-IRF7 gene regulatory circuit limits inflammatory sequelae of antiviral responses.

Published in:

Nature, 2012, v. 490, n. 7420, p. 421, doi. 10.1038/nature11428

By:

Litvak, Vladimir;
Ratushny, Alexander V.;
Lampano, Aaron E.;
Schmitz, Frank;
Huang, Albert C.;
Raman, Ayush;
Rust, Alistair G.;
Bergthaler, Andreas;
Aitchison, John D.;
Aderem, Alan

Publication type:

Article

The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma.

Published in:

Nature, 2012, v. 486, n. 7402, p. 266, doi. 10.1038/nature11114

By:

Pérez-Mancera, Pedro A.;
Rust, Alistair G.;
van der Weyden, Louise;
Kristiansen, Glen;
Li, Allen;
Sarver, Aaron L.;
Silverstein, Kevin A. T.;
Grützmann, Robert;
Aust, Daniela;
Rümmele, Petra;
Knösel, Thomas;
Herd, Colin;
Stemple, Derek L.;
Kettleborough, Ross;
Brosnan, Jacqueline A.;
Li, Ang;
Morgan, Richard;
Knight, Spencer;
Yu, Jun;
Stegeman, Shane

Publication type:

Article

Somatic drivers of B-ALL in a model of ETV6-RUNX1; Pax5+/- leukemia.

Published in:

BMC Cancer, 2015, v. 15, n. 1, p. 1, doi. 10.1186/s12885-015-1586-1

By:

van der Weyden, Louise;
Giotopoulos, George;
Kim Wong;
Rust, Alistair G.;
Robles-Espinoza, Carla Daniela;
Hikari Osaki;
Huntly, Brian J.;
Adams, David J.

Publication type:

Article

Somatic drivers of B-ALL in a model of ETV6-RUNX1; Pax5(+/-) leukemia.

Published in:

2015

By:

van der Weyden, Louise;
Giotopoulos, George;
Wong, Kim;
Rust, Alistair G;
Robles-Espinoza, Carla Daniela;
Osaki, Hikari;
Huntly, Brian J;
Adams, David J

Publication type:

journal article

Generation of the Sotos syndrome deletion in mice.

Published in:

Mammalian Genome, 2012, v. 23, n. 11/12, p. 749, doi. 10.1007/s00335-012-9416-0

By:

Migdalska, Anna;
Weyden, Louise;
Ismail, Ozama;
Rust, Alistair;
Rashid, Mamunur;
White, Jacqueline;
Sánchez-Andrade, Gabriela;
Lupski, James;
Logan, Darren;
Arends, Mark;
Adams, David

Publication type:

Article

The mutational landscapes of genetic and chemical models of Kras-driven lung cancer.

Published in:

Nature, 2015, v. 517, n. 7535, p. 489, doi. 10.1038/nature13898

By:

Westcott, Peter M. K.;
Halliwill, Kyle D.;
To, Minh D.;
Rashid, Mamunur;
Rust, Alistair G.;
Keane, Thomas M.;
Delrosario, Reyno;
Jen, Kuang-Yu;
Gurley, Kay E.;
Kemp, Christopher J.;
Fredlund, Erik;
Quigley, David A.;
Adams, David J.;
Balmain, Allan

Publication type:

Article

Analyzing tumor heterogeneity and driver genes in single myeloid leukemia cells with SBCapSeq.

Published in:

Nature Biotechnology, 2016, v. 34, n. 9, p. 962, doi. 10.1038/nbt.3637

By:

Mann, Karen M;
Newberg, Justin Y;
Black, Michael A;
Jones, Devin J;
Amaya-Manzanares, Felipe;
Guzman-Rojas, Liliana;
Kodama, Takahiro;
Ward, Jerrold M;
Rust, Alistair G;
van der Weyden, Louise;
Yew, Christopher Chin Kuan;
Waters, Jill L;
Leung, Marco L;
Rogers, Keith;
Rogers, Susan M;
McNoe, Leslie A;
Selvanesan, Luxmanan;
Navin, Nicholas;
Jenkins, Nancy A;
Copeland, Neal G

Publication type:

Article

Adenoma development in familial adenomatous polyposis and MUTYH-associated polyposis: somatic landscape and driver genes.

Published in:

Journal of Pathology, 2016, v. 238, n. 1, p. 98, doi. 10.1002/path.4643

By:

Rashid, Mamunur;
Fischer, Andrej;
Wilson, Cathy H;
Tiffen, Jessamy;
Rust, Alistair G;
Stevens, Philip;
Idziaszczyk, Shelley;
Maynard, Julie;
Williams, Geraint T;
Mustonen, Ville;
Sampson, Julian R;
Adams, David J

Publication type:

Article

Acute sensitivity of the oral mucosa to oncogenic K-ras.

Published in:

Journal of Pathology, 2011, v. 224, n. 1, p. 22, doi. 10.1002/path.2853

By:

van der Weyden, Louise;
Alcolea, Maria P;
Jones, Philip H;
Rust, Alistair G;
Arends, Mark J;
Adams, David J

Publication type:

Article

Works matching AU Rust, Alistair

Function of C/EBPδ in a regulatory circuit that discriminates between transient and persistent TLR4-induced signals.

The Mutational Concordance of Fixed Formalin Paraffin Embedded and Fresh Frozen Gastro-Oesophageal Tumours Using Whole Exome Sequencing.

A lentiviral vector‐based insertional mutagenesis screen identifies mechanisms of resistance to MAPK inhibitors in melanoma.

Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4.

Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4.

Insertional mutagenesis identifies multiple networks of cooperating genes driving intestinal tumorigenesis.

Chromatin Landscapes of Retroviral and Transposon Integration Profiles.

Insertional Mutagenesis and Deep Profiling Reveals Gene Hierarchies and a <i>Myc/p53</i>-Dependent Bottleneck in Lymphomagenesis.

Optimised ARID1A immunohistochemistry is an accurate predictor of ARID1A mutational status in gynaecological cancers.

A Genome-Wide Association Study for Regulators of Micronucleus Formation in Mice.

Transposon mutagenesis identifies genetic drivers of Braf<sup>V600E</sup> melanoma.

Transposon mutagenesis identifies genes and evolutionary forces driving gastrointestinal tract tumor progression.

Inactivating CUX1 mutations promote tumorigenesis.

Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse model.

Increased tumorigenesis associated with loss of the tumor suppressor gene Cadm1.

Cake: a bioinformatics pipeline for the integrated analysis of somatic variants in cancer genomes.

Integrating genomic binding site predictions using real-valued meta classifiers.

The Innate Immune Database (IIDB).

Uncovering a Macrophage Transcriptional Program by Integrating Evidence from Motif Scanning and Expression Dynamics.

A Data Integration Framework for Prediction of Transcription Factor Targets.

TRANSCRIPTION BINDING SITE PREDICTION USING MARKOV MODELS.

Capture Hi-C identifies putative target genes at 33 breast cancer risk loci.

Nuclear receptor binding protein 1 regulates intestinal progenitor cell homeostasis and tumour formation.

Probabilistic Inference of Transcription Factor Binding from Multiple Data Sources.

FFPE breast tumour blocks provide reliable sources of both germline and malignant DNA for investigation of genetic determinants of individual tumour responses to treatment.

Corrigendum: The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma.

A FOXO3-IRF7 gene regulatory circuit limits inflammatory sequelae of antiviral responses.

The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma.

Somatic drivers of B-ALL in a model of ETV6-RUNX1; Pax5<sup>+/-</sup> leukemia.

Somatic drivers of B-ALL in a model of ETV6-RUNX1; Pax5(+/-) leukemia.

Generation of the Sotos syndrome deletion in mice.

The mutational landscapes of genetic and chemical models of Kras-driven lung cancer.

Analyzing tumor heterogeneity and driver genes in single myeloid leukemia cells with SBCapSeq.

Adenoma development in familial adenomatous polyposis and MUTYH-associated polyposis: somatic landscape and driver genes.

Acute sensitivity of the oral mucosa to oncogenic K-ras.