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CXCR1/2 inhibition enhances pancreatic islet survival after transplantation.
Published in:
Journal of Clinical Investigation, 2012, v. 122, n. 10, p. 1, doi. 10.1172/JCI63089
By:
- Citro, Antonio;
- Cantarelli, Elisa;
- Maffi, Paola;
- Nano, Rita;
- Melzi, Raffaella;
- Mercalli, Alessia;
- Dugnani, Erica;
- Sordi, Valeria;
- Magistretti, Paola;
- Daffonchio, Luisa;
- Ruffini, Pier Adelchi;
- Allegretti, Marcello;
- Secchi, Antonio;
- Bonifacio, Ezio;
- Piemonti, Lorenzo
Publication type:
Article
A randomized, placebo-controlled phase 2 study of paclitaxel in combination with reparixin compared to paclitaxel alone as front-line therapy for metastatic triple-negative breast cancer (fRida).
Published in:
Breast Cancer Research & Treatment, 2021, v. 190, n. 2, p. 265, doi. 10.1007/s10549-021-06367-5
By:
- Goldstein, Lori J.;
- Mansutti, Mauro;
- Levy, Christelle;
- Chang, Jenny C.;
- Henry, Stephanie;
- Fernandez-Perez, Isaura;
- Prausovà, Jana;
- Staroslawska, Elzbieta;
- Viale, Giuseppe;
- Butler, Beth;
- McCanna, Susan;
- Ruffini, Pier Adelchi;
- Wicha, Max S.;
- Schott, Anne F.;
- for the fRida Trial Investigators;
- Alvarez, Ricardo H.;
- Abu-Khalaf, Maysa;
- Ibrahim, Nuhad;
- Daniel, Brooke;
- Meshad, Michael
Publication type:
Article
Fatigue in patients with metastatic breast cancer undergoing single-agent taxane-based chemotherapy: a real-world data global network.
Published in:
Therapeutic Advances in Medical Oncology, 2024, p. 1, doi. 10.1177/17588359241240972
By:
- Fabi, Alessandra;
- Gavioli, Elizabeth M.;
- Wakade, Renuka;
- Spera, Maria C.;
- Miracle, Santiago;
- Valveny, Neus;
- Butler, Elizabeth;
- DePizzol, Maria;
- Ruffini, Pier Adelchi;
- Allegretti, Marcello
Publication type:
Article
Ladarixin, an inhibitor of the interleukin‐8 receptors CXCR1 and CXCR2, in new‐onset type 1 diabetes: A multicentre, randomized, double‐blind, placebo‐controlled trial.
Published in:
Diabetes, Obesity & Metabolism, 2022, v. 24, n. 9, p. 1840, doi. 10.1111/dom.14770
By:
- Piemonti, Lorenzo;
- Keymeulen, Bart;
- Gillard, Pieter;
- Linn, Thomas;
- Bosi, Emanuele;
- Rose, Ludger;
- Pozzilli, Paolo;
- Giorgino, Francesco;
- Cossu, Efisio;
- Daffonchio, Luisa;
- Goisis, Giovanni;
- Ruffini, Pier Adelchi;
- Maurizi, Anna Rita;
- Mantelli, Flavio;
- Allegretti, Marcello
Publication type:
Article
Correction to: A window-of-opportunity trial of the CXCR1/2 inhibitor reparixin in operable HER-2-negative breast cancer.
Published in:
2020
By:
- Goldstein, Lori J.;
- Perez, Raymond P.;
- Yardley, Denise;
- Han, Linda K.;
- Reuben, James M.;
- Gao, Hui;
- McCanna, Susan;
- Butler, Beth;
- Ruffini, Pier Adelchi;
- Liu, Yi;
- Rosato, Roberto R.;
- Chang, Jenny C.
Publication type:
journal article
Armed antibodies for cancer treatment: a promising tool in a changing era.
Published in:
Cancer Immunology, Immunotherapy, 2015, v. 64, n. 1, p. 113, doi. 10.1007/s00262-014-1621-0
By:
- Danielli, Riccardo;
- Patuzzo, Roberto;
- Ruffini, Pier;
- Maurichi, Andrea;
- Giovannoni, Leonardo;
- Elia, Giuliano;
- Neri, Dario;
- Santinami, Mario
Publication type:
Article
A window-of-opportunity trial of the CXCR1/2 inhibitor reparixin in operable HER-2-negative breast cancer.
Published in:
2020
By:
- Goldstein, Lori J.;
- Perez, Raymond P.;
- Yardley, Denise;
- Han, Linda K.;
- Reuben, James M.;
- Gao, Hui;
- McCanna, Susan;
- Butler, Beth;
- Ruffini, Pier Adelchi;
- Liu, Yi;
- Rosato, Roberto R.;
- Chang, Jenny C.
Publication type:
journal article
Targeted idiotype-fusion DNA vaccines for human multiple myeloma: preclinical testing.
Published in:
European Journal of Haematology, 2011, v. 86, n. 5, p. 385, doi. 10.1111/j.1600-0609.2011.01590.x
By:
- Frøyland, Marianne;
- Ruffini, Pier Adelchi;
- Thompson, Keith Michael;
- Gedde-Dahl, Tobias;
- Fredriksen, Agnete Brunsvik;
- Bogen, Bjarne
Publication type:
Article
Manipulating the Chemokine-Chemokine Receptor Network to Treat Cancer.
Published in:
Cancer (0008543X), 2007, v. 109, n. 12, p. 2392, doi. 10.1002/cncr.22706
By:
- Ruffini, Pier A.;
- Morandi, Paolo;
- Cabioglu, Neslihan;
- Altundag, Kadri;
- Cristofanilli, Massimo
Publication type:
Article
The CXCL8-CXCR1/2 Axis as a Therapeutic Target in Breast Cancer Stem-Like Cells.
Published in:
Frontiers in Oncology, 2019, p. N.PAG, doi. 10.3389/fonc.2019.00040
By:
- Ruffini, Pier Adelchi
Publication type:
Article
Targeted DNA vaccines eliciting crossreactive anti-idiotypic antibody responses against human B cell malignancies in mice.
Published in:
2014
By:
- Ruffini, Pier Adelchi;
- Os, Audun;
- Dolcetti, Riccardo;
- Tjønnfjord, Geir E;
- Munthe, Ludvig A;
- Bogen, Bjarne
Publication type:
journal article
Prognostic role of human equilibrative transporter 1 (hENT1) in patients with resected gastric cancer.
Published in:
Journal of Cellular Physiology, 2010, v. 223, n. 2, p. 384, doi. 10.1002/jcp.22045
By:
- SANTINI, DANIELE;
- VINCENZI, BRUNO;
- FRATTO, MARIA ELISABETTA;
- PERRONE, GIUSEPPE;
- LAI, RAYMOND;
- CATALANO, VINCENZO;
- CASS, CAROL;
- RUFFINI, PIER ADELCHI;
- SPOTO, CHIARA;
- MURETTO, PIETRO;
- RIZZO, SERGIO;
- MUDA, ANDREA ONETTI;
- MACKEY, JOHN R.;
- RUSSO, ANTONIO;
- TONINI, GIUSEPPE;
- GRAZIANO, FRANCESCO
Publication type:
Article
The therapeutic potential of an allosteric non‐competitive CXCR1/2 antagonist for diabetic nephropathy.
Published in:
Diabetes/Metabolism Research & Reviews, 2023, v. 39, n. 7, p. 1, doi. 10.1002/dmrr.3694
By:
- Grasselli, Chiara;
- Bombelli, Silvia;
- D'Esposito, Vittoria;
- Di Tolla, Michele Francesco;
- L'Imperio, Vincenzo;
- Rocchio, Francesca;
- Miscione, Martina Sara;
- Formisano, Pietro;
- Pagni, Fabio;
- Novelli, Rubina;
- Ruffini, Pier Adelchi;
- Aramini, Andrea;
- Allegretti, Marcello;
- Perego, Roberto;
- De Filippis, Lidia
Publication type:
Article
Germ cell tumors overexpress the candidate therapeutic target cyclin B1 independently of p53 function.
Published in:
International Journal of Biological Markers, 2015, v. 30, n. 3, p. e275, doi. 10.5301/jbm.5000149
By:
- De Giorgi, Ugo;
- Juping Yuan;
- Moroni, Mauro;
- Veronese, Silvio;
- Sartore-Bianchi, Andrea;
- Broggini, Massimo;
- Rosti, Giovanni;
- Strebhardt, Klaus;
- Ruffini, Pier Adelchi
Publication type:
Article
Targeting CXCR1/2 Does Not Improve Insulin Secretion After Pancreatic Islet Transplantation: A Phase 3, Double-Blind, Randomized, Placebo-Controlled Trial in Type 1 Diabetes.
Published in:
2020
By:
- Maffi, Paola;
- Lundgren, Torbjörn;
- Tufveson, Gunnar;
- Rafael, Ehab;
- Shaw, James A. M.;
- Liew, Aaron;
- Saudek, Frantisek;
- Witkowski, Piotr;
- Golab, Karolina;
- Bertuzzi, Federico;
- Gustafsson, Bengt;
- Daffonchio, Luisa;
- Ruffini, Pier Adelchi;
- Piemonti, Lorenzo;
- and the REP0211 Study Group;
- REP0211 Study Group
Publication type:
journal article
Safety and Pharmacokinetics of Escalating Doses of Human Recombinant Nerve Growth Factor Eye Drops in a Double-Masked, Randomized Clinical Trial.
Published in:
BioDrugs, 2014, v. 28, n. 3, p. 275, doi. 10.1007/s40259-013-0079-5
By:
- Ferrari, Mauro;
- Mantelli, Flavio;
- Sacchetti, Marta;
- Antonangeli, Maria;
- Cattani, Franca;
- D'Anniballe, Gaetano;
- Sinigaglia, Francesco;
- Ruffini, Pier;
- Lambiase, Alessandro
Publication type:
Article
Combined negative and positive selection of mobilized CD34<sup>+</sup> blood cells.
Published in:
British Journal of Haematology, 1996, v. 94, n. 4, p. 716, doi. 10.1046/j.1365-2141.1996.00725.x
By:
- Di Nicola, Massimo;
- Bregni, Marco;
- Siena, Salvatore;
- Adelchi Ruffini, Pier;
- Milanesi, Marco;
- Ravagnani, Fernando;
- Massimo Gianni, A.
Publication type:
Article
249-OR: A Randomized, Double-Blind Phase 2 Trial of the CXCR1/2 Inhibitor Ladarixin in Adult Patients with New-Onset Type 1 Diabetes.
Published in:
Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-249-OR
By:
- BOSI, EMANUELE;
- POZZILLI, PAOLO;
- GIORGINO, FRANCESCO;
- COSSU, EFISIO;
- LINN, THOMAS;
- ROSE, LUDGER;
- KEYMEULEN SR., BART;
- GILLARD, PIETER;
- DAFFONCHIO, LUISA;
- RUFFINI, PIER A.;
- ALLEGRETTI, MARCELLO;
- PIEMONTI, LORENZO
Publication type:
Article
CXCR1/2 Inhibition Blocks and Reverses Type 1 Diabetes in Mice.
Published in:
Diabetes, 2015, v. 64, n. 4, p. 1329, doi. 10.2337/db14-0443
By:
- Citro, Antonio;
- Valle, Andrea;
- Cantarelli, Elisa;
- Mercalli, Alessia;
- Pellegrini, Silvia;
- Liberati, Daniela;
- Daffonchio, Luisa;
- Kastsiuchenka, Olga;
- Ruffini, Pier Adelchi;
- Battaglia, Manuela;
- Allegretti, Marcello;
- Piemonti, Lorenzo
Publication type:
Article

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