Works by Ruey-Hwa Chen

Results: 49

Identification of partners of TIF34, a component of the yeast eIF3 complex, required for cell proliferation and translation initiation.

Published in:

EMBO Journal, 1997, v. 16, n. 22, p. 6812, doi. 10.1093/emboj/16.22.6812

By:

Verlhac, Marie-Hélène;
Ruey-Hwa Chen;
Hanachi, Parisa;
Hershey, John W. B.;
Derynck, Rik

Publication type:

Article

Use of PCR amplification of cDNA to study mechanisms of human cell mutagenesis and malignant transformation.

Published in:

Environmental & Molecular Mutagenesis, 1991, v. 18, n. 4, p. 239, doi. 10.1002/em.2850180406

By:

Maher, Veronica M.;
Yang, Jia-Ling;
Chen, Ruey-Hwa;
McGregor, W. Glenn;
Lukash, Lubov;
Scheid, Jeanette M.;
Reinhold, David S.;
McCormick, J. Justin

Publication type:

Article

Correction to: Long noncoding RNA BCRP3 stimulates VPS34 and autophagy activities to promote protein homeostasis and cell survival.

Published in:

2022

By:

Yan, Ruei Liang;
Luan, Chiu Lin;
Liao, Chun Chieh;
Liu, Li Heng;
Chen, Fei Yun;
Chen, Hsin Yi;
Chen, Ruey Hwa

Publication type:

Correction Notice

Correction to: Long noncoding RNA BCRP3 stimulates VPS34 and autophagy activities to promote protein homeostasis and cell survival.

Published in:

2022

By:

Yan, Ruei Liang;
Luan, Chiu Lin;
Liao, Chun Chieh;
Liu, Li Heng;
Chen, Fei Yun;
Chen, Hsin Yi;
Chen, Ruey Hwa

Publication type:

Correction Notice

Long noncoding RNA BCRP3 stimulates VPS34 and autophagy activities to promote protein homeostasis and cell survival.

Published in:

Journal of Biomedical Science, 2022, v. 29, n. 1, p. 1, doi. 10.1186/s12929-022-00815-0

By:

Yan, Ruei-Liang;
Luan, Chiu-Lin;
Liao, Chun-Chieh;
Liu, Li-Heng;
Chen, Fei-Yun;
Chen, Hsin-Yi;
Chen, Ruey-Hwa

Publication type:

Article

Long noncoding RNA BCRP3 stimulates VPS34 and autophagy activities to promote protein homeostasis and cell survival.

Published in:

Journal of Biomedical Science, 2022, v. 29, n. 1, p. 1, doi. 10.1186/s12929-022-00815-0

By:

Yan, Ruei-Liang;
Luan, Chiu-Lin;
Liao, Chun-Chieh;
Liu, Li-Heng;
Chen, Fei-Yun;
Chen, Hsin-Yi;
Chen, Ruey-Hwa

Publication type:

Article

Ubiquitin-mediated regulation of autophagy.

Published in:

Journal of Biomedical Science, 2019, v. 26, n. 1, p. N.PAG, doi. 10.1186/s12929-019-0569-y

By:

Chen, Ruey-Hwa;
Chen, Yu-Hsuan;
Huang, Tzu-Yu

Publication type:

Article

Ubiquitination of tumor suppressor PML regulates prometastatic and immunosuppressive tumor microenvironment.

Published in:

2017

By:

Ya-Ting Wang;
Chen, Jocelyn;
Chou-Wei Chang;
Jayu Jen;
Tzu-Yu Huang;
Chun-Ming Chen;
Shen, Roger;
Suh-Yuen Liang;
I-Cheng Cheng;
Shuenn-Chen Yang;
Wu-Wei Lai;
Kuang-Hung Cheng;
Tao-Shih Hsieh;
Ming-Zong Lai;
Hung-Chi Cheng;
Yi-Ching Wang;
Ruey-Hwa Chen;
Wang, Ya-Ting;
Chang, Chou-Wei;
Jen, Jayu

Publication type:

journal article

Antibiotics induce apoptosis of human peritoneal mesothelial cells.

Published in:

Nephrology, 2003, v. 8, n. 3, p. 142, doi. 10.1046/j.1440-1797.2003.00149.x

By:

FANG, CHENG-CHUNG;
YEN, CHUNG-JEN;
TSAI, TUN-JUN;
CHEN, RUEY-HWA;
LEE, PO-HUANG;
TOMINO, YASUHIKO

Publication type:

Article

Autophagy and cancer metabolism—The two‐way interplay.

Published in:

IUBMB Life, 2022, v. 74, n. 4, p. 281, doi. 10.1002/iub.2569

By:

Yan, Reui‐Liang;
Chen, Ruey‐Hwa

Publication type:

Article

Cul3-KLHL20 ubiquitin ligase: physiological functions, stress responses, and disease implications.

Published in:

Cell Division, 2016, v. 11, p. 1, doi. 10.1186/s13008-016-0017-2

By:

Hsin-Yi Chen;
Chin-Chih Liu;
Ruey-Hwa Chen

Publication type:

Article

The tumor suppressor DAPK inhibits cell motility by blocking the integrin-mediated polarity pathway.

Published in:

Journal of Cell Biology, 2006, v. 172, n. 4, p. 619, doi. 10.1083/jcb.200505138

By:

Kuo, Jean-Cheng;
Won-Jing Wang;
Chung-Chen Yao;
Pei-Rung Wu;
Ruey-Hwa Chen

Publication type:

Article

DAP-kinase induces apoptosis by suppressing integrin activity and disrupting matrix survival signals.

Published in:

Journal of Cell Biology, 2002, v. 159, n. 1, p. 169, doi. 10.1083/jcb.200204050

By:

Won-Jing Wang;
Jean-Cheng Kou;
Chung-Chen Yao;
Ruey-Hwa Chen

Publication type:

Article

Suppression of autophagy during mitosis via CUL4-RING ubiquitin ligases-mediated WIPI2 polyubiquitination and proteasomal degradation.

Published in:

Autophagy, 2019, v. 15, n. 11, p. 1917, doi. 10.1080/15548627.2019.1596484

By:

Lu, Guang;
Yi, Juan;
Gubas, Andrea;
Wang, Ya-Ting;
Wu, Yihua;
Ren, Yi;
Wu, Man;
Shi, Yin;
Ouyang, Chenxi;
Tan, Hayden Weng Siong;
Wang, Tianru;
Wang, Liming;
Yang, Nai-Di;
Deng, Shuo;
Xia, Dajing;
Chen, Ruey-Hwa;
Tooze, Sharon A.;
Shen, Han-Ming

Publication type:

Article

Neurofibromin Mediates FAK Signaling in Confining Synapse Growth at Drosophila Neuromuscular Junctions.

Published in:

Journal of Neuroscience, 2012, v. 32, n. 47, p. 16971, doi. 10.1523/JNEUROSCI.1756-12.2012

By:

Tsai, Pei-I;
Wang, Manyu;
Kao, Hsiu-Hua;
Ying-Ju Cheng;
Walker, James A.;
Chen, Ruey-Hwa;
Cheng-Ting Chien

Publication type:

Article

Long non-coding RNA HOXB-AS3 promotes myeloid cell proliferation and its higher expression is an adverse prognostic marker in patients with acute myeloid leukemia and myelodysplastic syndrome.

Published in:

2019

By:

Huang, Huai-Hsuan;
Chen, Fei-Yun;
Chou, Wen-Chien;
Hou, Hsin-An;
Ko, Bor-Sheng;
Lin, Chien-Ting;
Tang, Jih-Luh;
Li, Chi-Cheng;
Yao, Ming;
Tsay, Woei;
Hsu, Szu-Chun;
Wu, Shang-Ju;
Chen, Chien-Yuan;
Huang, Shang-Yi;
Tseng, Mei-Hsuan;
Tien, Hwei-Fang;
Chen, Ruey-Hwa

Publication type:

journal article

miR-103/107 prolong Wnt/β-catenin signaling and colorectal cancer stemness by targeting Axin2.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-41053-z

By:

Chen, Hsin-Yi;
Lang, Yaw-Dong;
Lin, Han-Nan;
Liu, Yun-Ru;
Liao, Chun-Chieh;
Nana, André Wendindondé;
Yen, Yun;
Chen, Ruey-Hwa

Publication type:

Article

The role of PML ubiquitination in human malignancies.

Published in:

Journal of Biomedical Science, 2012, v. 19, n. 1, p. 81, doi. 10.1186/1423-0127-19-81

By:

Ruey-Hwa Chen;
Yu-Ru Lee;
Wei-Chien Yuan

Publication type:

Article

The tumor suppressor DAP-kinase links cell adhesion and cytoskeleton reorganization to cell death regulation.

Published in:

Journal of Biomedical Science, 2006, v. 13, n. 2, p. 193, doi. 10.1007/s11373-005-9063-5

By:

Ruey-Hwa Chen;
Won-Jing Wang;
Jean-Cheng Kuo

Publication type:

Article

A WD-domain protein that is associated with and phosphorylated by the type of II TGF-(beta)...

Published in:

Nature, 1995, v. 377, n. 6549, p. 548, doi. 10.1038/377548a0

By:

chen, Ruey-Hwa;
Miettinen, Palvi J.

Publication type:

Article

BIK ubiquitination by the E3 ligase Cul5-ASB11 determines cell fate during cellular stress.

Published in:

Journal of Cell Biology, 2019, v. 218, n. 9, p. 3002, doi. 10.1083/jcb.201901156

By:

Fei-Yun Chen;
Min-Yu Huang;
Yu-Min Lin;
Chi-Huan Ho;
Shu-Yu Lin;
Hsin-Yi Chen;
Mien-Chie Hung;
Ruey-Hwa Chen

Publication type:

Article

PDZ-RhoGEF ubiquitination by Cullin3-KLHL20 controls neurotrophin-induced neurite outgrowth.

Published in:

Journal of Cell Biology, 2011, v. 193, n. 6, p. 985, doi. 10.1083/jcb.201103015

By:

Mei-Yao Lin;
Yu-Min Lin;
Te-chan Kao;
Hsiang-Hao Chuang;
Ruey-Hwa Chen

Publication type:

Article

Tumour suppressor death-associated protein kinase targets cytoplasmic HIF-1α for Th17 suppression.

Published in:

Nature Communications, 2016, v. 7, n. 6, p. 11904, doi. 10.1038/ncomms11904

By:

Chou, Ting-Fang;
Chuang, Ya-Ting;
Hsieh, Wan-Chen;
Chang, Pei-Yun;
Liu, Hsin-Yu;
Mo, Shu-Ting;
Hsu, Tzu-Sheng;
Miaw, Shi-Chuen;
Chen, Ruey-Hwa;
Kimchi, Adi;
Lai, Ming-Zong

Publication type:

Article

Small GTPase Rab37 targets tissue inhibitor of metalloproteinase 1 for exocytosis and thus suppresses tumour metastasis.

Published in:

Nature Communications, 2014, v. 5, n. 9, p. 4804, doi. 10.1038/ncomms5804

By:

Tsai, Chung-Han;
Cheng, Hung-Chi;
Wang, Yu-Shiuan;
Lin, Pinpin;
Jen, Jayu;
Kuo, I-Ying;
Chang, Ying-Hua;
Liao, Pao-Chi;
Chen, Ruey-Hwa;
Yuan, Wei-Chien;
Hsu, Han-Shui;
Yang, Muh-Hwa;
Hsu, Ming-Ta;
Wu, Chu-Yi;
Wang, Yi-Ching

Publication type:

Article

USP11 regulates PML stability to control Notch-induced malignancy in brain tumours.

Published in:

Nature Communications, 2014, v. 5, n. 2, p. 3214, doi. 10.1038/ncomms4214

By:

Wu, Hsin-Chieh;
Lin, Yu-Ching;
Liu, Cheng-Hsin;
Chung, Hsiang-Ching;
Wang, Ya-Ting;
Lin, Ya-Wen;
Ma, Hsin-I.;
Tu, Pang-Hsien;
Lawler, Sean E.;
Chen, Ruey-Hwa

Publication type:

Article

Long noncoding RNA Smyca coactivates TGF-β/Smad and Myc pathways to drive tumor progression.

Published in:

Journal of Hematology & Oncology, 2022, v. 15, n. 1, p. 1, doi. 10.1186/s13045-022-01306-3

By:

Chen, Hsin-Yi;
Chan, Shu-Jou;
Liu, Xinxin;
Wei, An-Chi;
Jian, Ru-In;
Huang, Kuan-Wei;
Lang, Yaw-Dong;
Shih, Jou-Ho;
Liao, Chun-Chieh;
Luan, Chiu-Lin;
Kao, Yu-Tung;
Chiang, Shang-Yin;
Hsiao, Pei-Wen;
Jou, Yuh-Shan;
Chen, Yunching;
Chen, Ruey-Hwa

Publication type:

Article

KLHL20 links the ubiquitin-proteasome system to autophagy termination.

Published in:

Autophagy, 2016, v. 12, n. 5, p. 890, doi. 10.1080/15548627.2016.1157243

By:

Liu, Chin-Chih;
Chen, Ruey-Hwa

Publication type:

Article

The functions and regulations of DAPK in cancer metastasis.

Published in:

Apoptosis, 2014, v. 19, n. 2, p. 364, doi. 10.1007/s10495-013-0923-6

By:

Chen, Hsin-Yi;
Lee, Yu-Ru;
Chen, Ruey-Hwa

Publication type:

Article

Regulation of inflammation by DAPK.

Published in:

Apoptosis, 2014, v. 19, n. 2, p. 357, doi. 10.1007/s10495-013-0933-4

By:

Lai, Ming-Zong;
Chen, Ruey-Hwa

Publication type:

Article

Suppression of transforming growth factor-β-induced apoptosis through a phosphatidylinositol 3-kinase/Akt-dependent pathway.

Published in:

Oncogene, 1998, v. 17, n. 15, p. 1959, doi. 10.1038/sj.onc.1202111

By:

Chen, Ruey-Hwa;
Su, Yi-Hsien;
Chuang, Rachel LC;
Chang, Tien-Yun

Publication type:

Article

Integrative analyses of noncoding RNAs reveal the potential mechanisms augmenting tumor malignancy in lung adenocarcinoma.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 3, p. 1175, doi. 10.1093/nar/gkz1149

By:

Shih, Jou-Ho;
Chen, Hsin-Yi;
Lin, Shin-Chih;
Yeh, Yi-Chen;
Shen, Roger;
Lang, Yaw-Dong;
Wu, Dung-Chi;
Chen, Chien-Yu;
Chen, Ruey-Hwa;
Chou, Teh-Ying;
Jou, Yuh-Shan

Publication type:

Article

Erratum: USP11 regulates PML stability to control Notch-induced malignancy in brain tumours.

Published in:

Nature Communications, 2017, v. 8, n. 10, p. 16167, doi. 10.1038/ncomms16167

By:

Wu, Hsin-Chieh;
Lin, Yu-Ching;
Liu, Cheng-Hsin;
Chung, Hsiang-Ching;
Wang, Ya-Ting;
Lin, Ya-Wen;
Ma, Hsin-I.;
Tu, Pang-Hsien;
Lawler, Sean E.;
Chen, Ruey-Hwa

Publication type:

Article

The Cullin 3 substrate adaptor KLHL20 mediates DAPK ubiquitination to control interferon responses.

Published in:

EMBO Journal, 2010, v. 29, n. 10, p. 1748, doi. 10.1038/emboj.2010.62

By:

Yu-Ru Lee;
Wei-Chien Yuan;
Hsuan-Chung Ho;
Chun-Hau Chen;
Hsiu-Ming Shih;
Ruey-Hwa Chen

Publication type:

Article

Bidirectional signals transduced by DAPK-ERK interaction promote the apoptotic effect of DAPK.

Published in:

EMBO Journal, 2005, v. 24, n. 2, p. 294, doi. 10.1038/sj.emboj.7600510

By:

Chen, Chun-Hau;
Wang, Won-Jing;
Kuo, Jean-Cheng;
Tsai, Hsiao-Chien;
Lin, Jia-Ren;
Chang, Zee-Fen;
Chen, Ruey-Hwa

Publication type:

Article

Membrane Protein Modification Modulates Big and Small Extracellular Vesicle Biodistribution and Tumorigenic Potential in Breast Cancers In Vivo.

Published in:

Advanced Materials, 2023, v. 35, n. 13, p. 1, doi. 10.1002/adma.202208966

By:

Magoling, Bryan John Abel;
Wu, Anthony Yan‐Tang;
Chen, Yen‐Ju;
Wong, Wendy Wan‐Ting;
Chuo, Steven Ting‐Yu;
Huang, Hsi‐Chien;
Sung, Yun‐Chieh;
Hsieh, Hsin Tzu;
Huang, Poya;
Lee, Kang‐Zhang;
Huang, Kuan‐Wei;
Chen, Ruey‐Hwa;
Chen, Yunching;
Lai, Charles Pin‐Kuang

Publication type:

Article

Cullin 3 Ubiquitin Ligases in Cancer Biology: Functions and Therapeutic implications.

Published in:

Frontiers in Oncology, 2016, p. 1, doi. 10.3389/fonc.2016.00113

By:

Hsin-Yi Chen;
Ruey-Hwa Chen

Publication type:

Article

TGF-β induces apoptosis through Smad-mediated expression of DAP-kinase.

Published in:

Nature Cell Biology, 2002, v. 4, n. 1, p. 51, doi. 10.1038/ncb731

By:

Jang, Chuan-Wei;
Chen, Chun-Hau;
Chen, Chun-Chieh;
Chen, Jia-yun;
Su, Yi-Hsien;
Chen, Ruey-Hwa

Publication type:

Article

VPS34 K29/K48 branched ubiquitination governed by UBE3C and TRABID regulates autophagy, proteostasis and liver metabolism.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-21715-1

By:

Chen, Yu-Hsuan;
Huang, Tzu-Yu;
Lin, Yu-Tung;
Lin, Shu-Yu;
Li, Wen-Hsin;
Hsiao, Hsiang-Jung;
Yan, Ruei-Liang;
Tang, Hong-Wen;
Shen, Zhao-Qing;
Chen, Guang-Chao;
Wu, Kuen-Phon;
Tsai, Ting-Fen;
Chen, Ruey-Hwa

Publication type:

Article

Fibroblast Activation Protein (FAP) Is Essential for the Migration of Bone Marrow Mesenchymal Stem Cells through RhoA Activation.

Published in:

PLoS ONE, 2014, v. 9, n. 2, p. 1, doi. 10.1371/journal.pone.0088772

By:

Chung, Kuei-Min;
Hsu, Shu-Ching;
Chu, Yue-Ru;
Lin, Mei-Yao;
Jiaang, Weir-Tong;
Chen, Ruey-Hwa;
Chen, Xin

Publication type:

Article

C. elegans EIF-3.K Promotes Programmed Cell Death through CED-3 Caspase.

Published in:

PLoS ONE, 2012, v. 7, n. 5, p. 1, doi. 10.1371/journal.pone.0036584

By:

Chun-Yi Huang;
Jia-Yun Chen;
Shu-Chun Wu;
Chieh-Hsiang Tan;
Ruei-Ying Tzeng;
Pei-Ju Lu;
Yu-Feng Wu;
Ruey-Hwa Chen;
Yi-Chun Wu

Publication type:

Article

Regulation of autophagy by VPS34 branched ubiquitination controls proteostasis and liver metabolism.

Published in:

Molecular & Cellular Oncology, 2021, v. 8, n. 3, p. 1, doi. 10.1080/23723556.2021.1915076

By:

Chen, Yu-Hsuan;
Chen, Ruey-Hwa

Publication type:

Article

Brk Activates Rac1 and Promotes Cell Migration and Invasion by Phosphorylating Paxillin.

Published in:

Molecular & Cellular Biology, 2004, v. 24, n. 24, p. 10558, doi. 10.1128/MCB.24.24.10558-10572.2004

By:

Hsin-Yi Chen;
Che-Hung Shen;
Yuh-Tyng Tsai;
Feng-Chi Lin;
Yuan-Ping Huang;
Ruey-Hwa Chen

Publication type:

Article

Branched Ubiquitination: Detection Methods, Biological Functions and Chemical Synthesis.

Published in:

Molecules, 2020, v. 25, n. 21, p. 5200, doi. 10.3390/molecules25215200

By:

Wang, Yane-Shih;
Wu, Kuen-Phon;
Jiang, Han-Kai;
Kurkute, Prashant;
Chen, Ruey-Hwa;
Polge, Cécile;
Vertegaal, Alfred

Publication type:

Article

MicroRNA-140-5p inhibits hepatocellular carcinoma by directly targeting the unique isomerase Pin1 to block multiple cancer-driving pathways.

Published in:

Scientific Reports, 2017, p. 45915, doi. 10.1038/srep45915

By:

Yan, Xingxue;
Zhu, Zhendong;
Xu, Shenmin;
Yang, Li-nan;
Liao, Xin-Hua;
Zheng, Min;
Yang, Dayun;
Wang, Jichuang;
Chen, Dongmei;
Wang, Long;
Liu, Xiaolong;
Liu, Jingfeng;
Chen, Ruey-Hwa;
Zhen Zhou, Xiao;
Ping Lu, Kun;
Liu, Hekun

Publication type:

Article

PSPC1-interchanged interactions with PTK6 and β-catenin synergize oncogenic subcellular translocations and tumor progression.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-13665-6

By:

Lang, Yaw-Dong;
Chen, Hsin-Yi;
Ho, Chun-Ming;
Shih, Jou-Ho;
Hsu, En-Chi;
Shen, Roger;
Lee, Yu-Ching;
Chen, Jyun-Wei;
Wu, Cheng-Yen;
Yeh, Hsi-Wen;
Chen, Ruey-Hwa;
Jou, Yuh-Shan

Publication type:

Article

Correction: PTPN23 ubiquitination by WDR4 suppresses EGFR and c-MET degradation to define a lung cancer therapeutic target.

Published in:

2024

By:

Singh, Shaifali;
Yeat, Nai Yang;
Wang, Ya-Ting;
Lin, Shu-Yu;
Kuo, I-Ying;
Wu, Kuen-Phon;
Wang, Won-Jing;
Wang, Wen-Ching;
Su, Wu-Chou;
Wang, Yi-Ching;
Chen, Ruey-Hwa

Publication type:

Correction Notice

PTPN23 ubiquitination by WDR4 suppresses EGFR and c-MET degradation to define a lung cancer therapeutic target.

Published in:

Cell Death & Disease, 2023, v. 14, n. 10, p. 1, doi. 10.1038/s41419-023-06201-4

By:

Singh, Shaifali;
Yeat, Nai Yang;
Wang, Ya-Ting;
Lin, Shu-Yu;
Kuo, I-Ying;
Wu, Kuen-Phon;
Wang, Won-Jing;
Wang, Wen-Ching;
Su, Wu-Chou;
Wang, Yi-Ching;
Chen, Ruey-Hwa

Publication type:

Article

Wdr4 promotes cerebellar development and locomotion through Arhgap17-mediated Rac1 activation.

Published in:

Cell Death & Disease, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41419-022-05442-z

By:

Wu, Pei-Rung;
Chiang, Shang-Yin;
Midence, Robert;
Kao, Wen-Chao;
Lai, Chun-Lun;
Cheng, I-Cheng;
Chou, Shen-Ju;
Chen, Chih-Cheng;
Huang, Chih-Yang;
Chen, Ruey-Hwa

Publication type:

Article

Tumor suppressor death-associated protein kinase 1 inhibits necroptosis by p38 MAPK activation.

Published in:

Cell Death & Disease, 2020, v. 11, n. 5, p. 1, doi. 10.1038/s41419-020-2534-9

By:

Wu, Yung-Hsuan;
Chou, Ting-Fang;
Young, Leslie;
Hsieh, Fu-Yi;
Pan, Hsuan-Yin;
Mo, Shu-Ting;
Brown, Shani Bialik;
Chen, Ruey-Hwa;
Kimchi, Adi;
Lai, Ming-Zong

Publication type:

Article