Works by Rudolph, Markus G.

Results: 19

Crystal structure of the murine NK cell?activating receptor NKG2D at 1.95 Å.

Published in:

Nature Immunology, 2001, v. 2, n. 3, p. 248, doi. 10.1038/85311

By:

Wolan, Dennis W.;
Teyton, Luc;
Rudolph, Markus G.;
Villmow, Brigitte;
Bauer, Stefan;
Busch, Dirk H.;
Wilson, Ian A.

Publication type:

Article

Structure of reverse gyrase with a minimal latch that supports ATP‐dependent positive supercoiling without specific interactions with the topoisomerase domain.

Published in:

Acta Crystallographica: Section D, Structural Biology, 2023, v. 79, n. 6, p. 498, doi. 10.1107/S2059798323002565

By:

Mhaindarkar, Vaibhav P.;
Rasche, René;
Kümmel, Daniel;
Rudolph, Markus G.;
Klostermeier, Dagmar

Publication type:

Article

Recognition of two distinct elements in the RNA substrate by the RNA-binding domain of the T. thermophilus DEAD box helicase Hera.

Published in:

Nucleic Acids Research, 2013, v. 41, n. 12, p. 6259, doi. 10.1093/nar/gkt323

By:

Steimer, Lenz;
Wurm, Jan Philip;
Linden, Martin H.;
Rudolph, Markus G.;
Wöhnert, Jens;
Klostermeier, Dagmar

Publication type:

Article

Crystal structures of Thermotoga maritima reverse gyrase: inferences for the mechanism of positive DNA supercoiling.

Published in:

Nucleic Acids Research, 2013, v. 41, n. 2, p. 1058, doi. 10.1093/nar/gks1073

By:

Rudolph, Markus G.;
del Toro Duany, Yoandris;
Jungblut, Stefan P.;
Ganguly, Agneyo;
Klostermeier, Dagmar

Publication type:

Article

The latch modulates nucleotide and DNA binding to the helicase-like domain of Thermotoga maritima reverse gyrase and is required for positive DNA supercoiling.

Published in:

Nucleic Acids Research, 2011, v. 39, n. 5, p. 1789, doi. 10.1093/nar/gkq1048

By:

Ganguly, Agneyo;
del Toro Duany, Yoandris;
Rudolph, Markus G.;
Klostermeier, Dagmar

Publication type:

Article

A novel dimerization motif in the C-terminal domain of the Thermus thermophilus DEAD box helicase Hera confers substantial flexibility†.

Published in:

Nucleic Acids Research, 2009, v. 37, n. 2, p. 421, doi. 10.1093/nar/gkn947

By:

Klostermeier, Dagmar;
Rudolph, Markus G.

Publication type:

Article

When core competence is not enough: functional interplay of the DEAD-box helicase core with ancillary domains and auxiliary factors in RNA binding and unwinding.

Published in:

Biological Chemistry, 2015, v. 396, n. 8, p. 849, doi. 10.1515/hsz-2014-0277

By:

Rudolph, Markus G.;
Klostermeier, Dagmar

Publication type:

Article

Changing nucleotide specificity of the DEAD-box helicase Hera abrogates communication between the Q-motif and the P-loop.

Published in:

Biological Chemistry, 2011, v. 392, n. 4, p. 357, doi. 10.1515/BC.2011.034

By:

Strohmeier, Julian;
Hertel, Ines;
Diederichsen, Ulf;
Rudolph, Markus G.;
Klostermeier, Dagmar

Publication type:

Article

D3R Grand Challenge 2: blind prediction of protein-ligand poses, affinity rankings, and relative binding free energies.

Published in:

Journal of Computer-Aided Molecular Design, 2018, v. 32, n. 1, p. 1, doi. 10.1007/s10822-017-0088-4

By:

Gaieb, Zied;
Liu, Shuai;
Gathiaka, Symon;
Chiu, Michael;
Yang, Huanwang;
Shao, Chenghua;
Feher, Victoria A.;
Walters, W. Patrick;
Kuhn, Bernd;
Rudolph, Markus G.;
Burley, Stephen K.;
Gilson, Michael K.;
Amaro, Rommie E.

Publication type:

Article

TIP47 functions in the biogenesis of lipid droplets.

Published in:

Journal of Cell Biology, 2009, v. 185, n. 4, p. 641, doi. 10.1083/jcb.200812042

By:

Bulankina, Anna V.;
Deggerich, Anke;
Wenzel, Dirk;
Mutenda, Kudzai;
Wittmann, Julia G.;
Rudolph, Markus G.;
Burger, Koert N. J.;
Höning, Stefan

Publication type:

Article

Synthesis, Characterization, and in vivo Evaluation of a Novel Potent Autotaxin-Inhibitor.

Published in:

Frontiers in Pharmacology, 2022, v. 12, p. 1, doi. 10.3389/fphar.2021.699535

By:

Hunziker, Daniel;
Reinehr, Sabrina;
Palmhof, Marina;
Wagner, Natalie;
Biniasch, Thomas;
Stute, Gesa;
Mattei, Patrizio;
Schmitz, Petra;
DiGiorgio, Patrick;
Hert, Jérôme;
Rudolph, Markus G.;
Benz, Joerg;
Stihle, Martine;
Gsell, Bernard;
Müller, Stephan;
Gasser, Rodolfo;
Schonhoven, Nina;
Ullmer, Christoph;
Joachim, Stephanie C.

Publication type:

Article

Details Matter in Structure-based Drug Design.

Published in:

Chimia, 2023, v. 77, n. 7/8, p. 489, doi. 10.2533/chimia.2023.489

By:

Kuhn, Bernd;
Peters, Jens-Uwe;
Rudolph, Markus G.;
Mohr, Peter;
Stahl, Martin;
Tosstorff, Andreas

Publication type:

Article

Crystal structure of Rab9 complexed to GDP reveals a dimer with an active conformation of switch II

Published in:

FEBS Letters, 2004, v. 568, n. 1-3, p. 23, doi. 10.1016/j.febslet.2004.05.004

By:

Wittmann, Julia G.;
Rudolph, Markus G.

Publication type:

Article

The novel fluorescent CDP-analogue (Pβ)MABA-CDP is a specific probe for the NMP binding site of UMP/CMP kinase.

Published in:

Protein Science: A Publication of the Protein Society, 1999, v. 8, n. 12, p. 2697, doi. 10.1110/ps.8.12.2697

By:

Rudolph, Markus G.;
Veit, THOMAS J.H.;
Reinstein, Jochen

Publication type:

Article

Molecular Recognition at the Active Site of Catechol- O-methyltransferase (COMT): Adenine Replacements in Bisubstrate Inhibitors.

Published in:

Chemistry - A European Journal, 2011, v. 17, n. 23, p. 6369, doi. 10.1002/chem.201003648

By:

Ellermann, Manuel;
Paulini, Ralph;
Jakob-Roetne, Roland;
Lerner, Christian;
Borroni, Edilio;
Roth, Doris;
Ehler, Andreas;
Schweizer, W. Bernd;
Schlatter, Daniel;
Rudolph, Markus G.;
Diederich, François

Publication type:

Article

A high quality, industrial data set for binding affinity prediction: performance comparison in different early drug discovery scenarios.

Published in:

Journal of Computer-Aided Molecular Design, 2022, v. 36, n. 10, p. 753, doi. 10.1007/s10822-022-00478-x

By:

Tosstorff, Andreas;
Rudolph, Markus G.;
Cole, Jason C.;
Reutlinger, Michael;
Kramer, Christian;
Schaffhauser, Hervé;
Nilly, Agnès;
Flohr, Alexander;
Kuhn, Bernd

Publication type:

Article

Domain swap in the C‐terminal ubiquitin‐like domain of human doublecortin.

Published in:

Acta Crystallographica: Section D, Structural Biology, 2018, v. 74, n. 5, p. 450, doi. 10.1107/S2059798318004813

By:

Rufer, Arne C.;
Kusznir, Eric;
Burger, Dominique;
Stihle, Martine;
Ruf, Armin;
Rudolph, Markus G.

Publication type:

Article

Quadruple space-group ambiguity owing to rotational and translational noncrystallographic symmetry in human liver fructose-1,6-bisphosphatase.

Published in:

Acta Crystallographica: Section D, Structural Biology, 2016, v. 72, n. 11, p. 1212, doi. 10.1107/S2059798316016715

By:

Ruf, Armin;
Tetaz, Tim;
Schott, Brigitte;
Joseph, Catherine;
Rudolph, Markus G.

Publication type:

Article

Structure of the malaria vaccine candidate antigen CyRPA and its complex with a parasite invasion inhibitory antibody.

Published in:

eLife, 2017, p. 1, doi. 10.7554/eLife.20383

By:

Favuzza, Paola;
Guffart, Elena;
Tamborrini, Marco;
Scherer, Bianca;
Dreyer, Anita M.;
Rufer, Arne C.;
Erny, Johannes;
Hoernschemeyer, Joerg;
Thoma, Ralf;
Schmid, Georg;
Gsell, Bernard;
Lamelas, Araceli;
Benz, Joerg;
Joseph, Catherine;
Matile, Hugues;
Pluschke, Gerd;
Rudolph, Markus G.

Publication type:

Article