Works by Rubinsztein, David C

Results: 165
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    Autophagy in malignant transformation and cancer progression.

    Published in:
    EMBO Journal, 2015, v. 34, n. 7, p. 856, doi. 10.15252/embj.201490784
    By:
    • Galluzzi, Lorenzo;
    • Pietrocola, Federico;
    • Bravo‐San Pedro, José Manuel;
    • Amaravadi, Ravi K;
    • Baehrecke, Eric H;
    • Cecconi, Francesco;
    • Codogno, Patrice;
    • Debnath, Jayanta;
    • Gewirtz, David A;
    • Karantza, Vassiliki;
    • Kimmelman, Alec;
    • Kumar, Sharad;
    • Levine, Beth;
    • Maiuri, Maria Chiara;
    • Martin, Seamus J;
    • Penninger, Josef;
    • Piacentini, Mauro;
    • Rubinsztein, David C;
    • Simon, Hans‐Uwe;
    • Simonsen, Anne
    Publication type:
    Article
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    P3-265: Testing for association between Alzheimer's disease with psychosis and variants identified as influencing risk of schizophrenia

    Published in:
    2008
    By:
    • Sims, Rebecca;
    • Hollingworth, Paul;
    • Morgan, Angharad;
    • Dowzell, Kimberley;
    • Stretton, Alexandra;
    • Jones, Laura;
    • Norton, Nadine;
    • Williams, Hywel;
    • Georgieva, Lyudmila;
    • Moskvina, Valentina;
    • Nikolov, Ivan;
    • Hamshere, Marian;
    • Holmans, Peter;
    • Lovestone, Simon;
    • Brayne, Carol;
    • Rubinsztein, David C.;
    • Williams, Nigel M.;
    • Kirov, George;
    • Craddock, Nick;
    • O'Donovan, Michael
    Publication type:
    Abstract
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    P1-335: A powerful association analysis of 496 SNPs in 80 positional candidate genes in a linked region on chromosome 10 for association with late onset Alzheimer’s disease

    Published in:
    2006
    By:
    • Abraham, Richard;
    • Morgan, Angharad R.;
    • Jehu, Luke;
    • Turic, Dragana;
    • Hamilton, Gillian;
    • Hollingworth, Paul;
    • Moore, Pamela;
    • Dowzell, Kimberley;
    • Holmans, Peter;
    • Moskvina, Valentina;
    • Cope, Natalie;
    • Powell, John;
    • Lovestone, Simon;
    • Brayne, Carol;
    • Rubinsztein, David C.;
    • O’Donovan, Michael;
    • Owen, Michael J.;
    • Williams, Julie
    Publication type:
    Abstract
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    P1-335: A powerful association analysis of 496 SNPs in 80 positional candidate genes in a linked region on chromosome 10 for association with late onset Alzheimer’s disease

    Published in:
    2006
    By:
    • Abraham, Richard;
    • Morgan, Angharad R.;
    • Jehu, Luke;
    • Turic, Dragana;
    • Hamilton, Gillian;
    • Hollingworth, Paul;
    • Moore, Pamela;
    • Dowzell, Kimberley;
    • Holmans, Peter;
    • Moskvina, Valentina;
    • Cope, Natalie;
    • Powell, John;
    • Lovestone, Simon;
    • Brayne, Carol;
    • Rubinsztein, David C.;
    • O’Donovan, Michael;
    • Owen, Michael J.;
    • Williams, Julie
    Publication type:
    Abstract
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    Absence of Relationship Between MTTP Haplotypes and Longevity.

    Published in:
    Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2007, v. 62, n. 2, p. 202, doi. 10.1093/gerona/62.2.202
    By:
    • Neville, Matt J.;
    • Clarke, Robert;
    • Evans, John Grimley;
    • Rubinsztein, David C.;
    • Karpe, Fredrik
    Publication type:
    Article
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    Lysosomal positioning coordinates cellular nutrient responses.

    Published in:
    Nature Cell Biology, 2011, v. 13, n. 4, p. 453, doi. 10.1038/ncb2204
    By:
    • Korolchuk, Viktor I.;
    • Saiki, Shinji;
    • Lichtenberg, Maike;
    • Siddiqi, Farah H.;
    • Roberts, Esteban A.;
    • Imarisio, Sara;
    • Jahreiss, Luca;
    • Sarkar, Sovan;
    • Futter, Marie;
    • Menzies, Fiona M.;
    • O'Kane, Cahir J.;
    • Deretic, Vojo;
    • Rubinsztein, David C.
    Publication type:
    Article
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    Oxidation of SQSTM1/p62 mediates the link between redox state and protein homeostasis.

    Published in:
    Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-017-02746-z
    By:
    • Carroll, Bernadette;
    • Otten, Elsje G.;
    • Manni, Diego;
    • Stefanatos, Rhoda;
    • Menzies, Fiona M.;
    • Smith, Graham R.;
    • Jurk, Diana;
    • Kenneth, Niall;
    • Wilkinson, Simon;
    • Passos, Joao F.;
    • Attems, Johannes;
    • Veal, Elizabeth A.;
    • Teyssou, Elisa;
    • Seilhean, Danielle;
    • Millecamps, Stéphanie;
    • Eskelinen, Eeva-Liisa;
    • Bronowska, Agnieszka K.;
    • Rubinsztein, David C.;
    • Sanz, Alberto;
    • Korolchuk, Viktor I.
    Publication type:
    Article
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    Four Components Describe Behavioral Symptoms in 1,120 Individuals with Late-Onset Alzheimer's Disease.

    Published in:
    Journal of the American Geriatrics Society, 2006, v. 54, n. 9, p. 1348, doi. 10.1111/j.1532-5415.2006.00854.x
    By:
    • Hollingworth, Paul;
    • Hamshere, Marian L.;
    • Moskvina, Valentina;
    • Dowzell, Kimberley;
    • Moore, Pamela J.;
    • Foy, Catherine;
    • Archer, Nicola;
    • Lynch, Aoibhinn;
    • Lovestone, Simon;
    • Brayne, Carol;
    • Rubinsztein, David C.;
    • Lawlor, Brian;
    • Gill, Mike;
    • Owen, Michael J.;
    • Williams, Julie
    Publication type:
    Article
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    Chemotherapy for the Brain: The Antitumor Antibiotic Mithramycin Prolongs Survival in a Mouse Model of Huntington's Disease.

    Published in:
    Journal of Neuroscience, 2004, v. 24, n. 46, p. 10335, doi. 10.1523/JNEUROSCI.2599-04.2004
    By:
    • Ferrante, Robert J.;
    • Ryu, Hoon;
    • Kubilus, James K.;
    • Lee, Junghee;
    • Smith, Karen;
    • D'Mello, Santosh;
    • Sugars, Katharine L.;
    • Rubinsztein, David C.;
    • Lu, Peiyuan;
    • Langley, Brett;
    • Browne, Susan;
    • Beal, M. Flint;
    • Hewett, Sandra;
    • Kristal, Bruce S.;
    • Stavrovskaya, Irina G.;
    • Ratan, Rajiv R.
    Publication type:
    Article
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    Autophagy: where next?

    Published in:
    EMBO Reports, 2010, v. 11, n. 1, p. 3, doi. 10.1038/embor.2009.253
    By:
    • Rubinsztein, David C.
    Publication type:
    Article
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    Meeting Summary of The NYO3 5th NO-Age/AD Meeting and the 1st Norway–UK Joint Meeting on Aging and Dementia: Recent Progress on the Mechanisms and Interventional Strategies.

    Published in:
    Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2024, v. 79, n. 4, p. 1, doi. 10.1093/gerona/glae029
    By:
    • Wang, He-Ling;
    • Siow, Richard;
    • Schmauck-Medina, Tomas;
    • Zhang, Jianying;
    • Sandset, Per Morten;
    • Filshie, Clare;
    • Lund, Øystein;
    • Partridge, Linda;
    • Bergersen, Linda Hildegard;
    • Rasmussen, Lene Juel;
    • Palikaras, Konstantinos;
    • Sotiropoulos, Ioannis;
    • Storm-Mathisen, Jon;
    • Rubinsztein, David C;
    • Spillantini, Maria Grazia;
    • Zeeuw, Chris I De;
    • Watne, Leiv Otto;
    • Vyhnalek, Martin;
    • Veverova, Katerina;
    • Liang, Kristina Xiao
    Publication type:
    Article
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    PSMC5 insufficiency and P320R mutation impair proteasome function.

    Published in:
    Human Molecular Genetics, 2024, v. 33, n. 17, p. 1506, doi. 10.1093/hmg/ddae085
    By:
    • Yu, Zhong-Qiu;
    • Carmichael, Jenny;
    • Collins, Galen A;
    • D'Agostino, Maria Daniela;
    • Lessard, Mathieu;
    • Firth, Helen V;
    • Harijan, Pooja;
    • Fry, Andrew E;
    • Dean, John;
    • Zhang, Jiuchun;
    • Kini, Usha;
    • Goldberg, Alfred L;
    • Rubinsztein, David C
    Publication type:
    Article
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    A genetic modifier suggests that endurance exercise exacerbates Huntington's disease.

    Published in:
    Human Molecular Genetics, 2018, v. 27, n. 10, p. 1723, doi. 10.1093/hmg/ddy077
    By:
    • Corrochano, Silvia;
    • Blanco, Gonzalo;
    • Williams, Debbie;
    • Wettstein, Jessica;
    • Simon, Michelle;
    • Kumar, Saumya;
    • Moir, Lee;
    • Agnew, Thomas;
    • Stewart, Michelle;
    • Landman, Allison;
    • Kotiadis, Vassilios N.;
    • Duchen, Michael R.;
    • Wackerhage, Henning;
    • Rubinsztein, David C.;
    • Brown, Steve D. M.;
    • Acevedo-Arozena, Abraham
    Publication type:
    Article
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    α-2 macroglobulin polymorphism and Alzheimer disease risk in the UK.

    Published in:
    Nature Genetics, 1999, v. 22, n. 1, p. 16, doi. 10.1038/8724
    By:
    • Dow, David J.;
    • Lindsey, Nicola;
    • Cairns, Nigel J.;
    • Brayne, Carol;
    • Robinson, Damian;
    • Huppert, Felicia A.;
    • Paykel, Eugene S.;
    • Xuereb, John;
    • Wilcock, Gordon;
    • Whittaker, Joanne L.;
    • Rubinsztein, David C.
    Publication type:
    Article
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    Author Correction: Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing.

    Published in:
    2019
    By:
    • Siddiqi, Farah H.;
    • Menzies, Fiona M.;
    • Lopez, Ana;
    • Stamatakou, Eleanna;
    • Karabiyik, Cansu;
    • Ureshino, Rodrigo;
    • Ricketts, Thomas;
    • Jimenez-Sanchez, Maria;
    • Esteban, Miguel Angel;
    • Lai, Liangxue;
    • Tortorella, Micky D.;
    • Luo, Zhiwei;
    • Liu, Hao;
    • Metzakopian, Emmanouil;
    • Fernandes, Hugo J. R.;
    • Bassett, Andrew;
    • Karran, Eric;
    • Miller, Bruce L.;
    • Fleming, Angeleen;
    • Rubinsztein, David C.
    Publication type:
    Correction Notice
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    Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing.

    Published in:
    Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-09494-2
    By:
    • Siddiqi, Farah H.;
    • Menzies, Fiona M.;
    • Lopez, Ana;
    • Stamatakou, Eleanna;
    • Karabiyik, Cansu;
    • Ureshino, Rodrigo;
    • Ricketts, Thomas;
    • Jimenez-Sanchez, Maria;
    • Esteban, Miguel Angel;
    • Lai, Liangxue;
    • Tortorella, Micky D.;
    • Luo, Zhiwei;
    • Liu, Hao;
    • Metzakopian, Emmanouil;
    • Fernandes, Hugo J. R.;
    • Bassett, Andrew;
    • Karran, Eric;
    • Miller, Bruce L.;
    • Fleming, Angeleen;
    • Rubinsztein, David C.
    Publication type:
    Article
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    Autophagy and mammalian development.

    Published in:
    Biochemical Society Transactions, 2013, v. 41, n. 6, p. 1489, doi. 10.1042/BST20130185
    By:
    • Xiaoting Wu;
    • Won, Hyeran;
    • Rubinsztein, David C.
    Publication type:
    Article
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    A152T tau allele causes neurodegeneration that can be ameliorated in a zebrafish model by autophagy induction.

    Published in:
    2017
    By:
    • Lopez, Ana;
    • Lee, Suzee E.;
    • Wojta, Kevin;
    • Ramos, Eliana Marisa;
    • Klein, Eric;
    • Chen, Jason;
    • Boxer, Adam L.;
    • Gorno-Tempini, Maria Luisa;
    • Geschwind, Daniel H.;
    • Schlotawa, Lars;
    • Ogryzko, Nikolay V.;
    • Bigio, Eileen H.;
    • Rogalski, Emily;
    • Weintraub, Sandra;
    • Mesulam, Marsel M.;
    • Consortium, Tauopathy Genetics;
    • Fleming, Angeleen;
    • Coppola, Giovanni;
    • Miller, Bruce L.;
    • Rubinsztein, David C.
    Publication type:
    journal article
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