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Accuracy of mutational signature software on correlated signatures.
Published in:
Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-021-04207-6
By:
- Wu, Yang;
- Chua, Ellora Hui Zhen;
- Ng, Alvin Wei Tian;
- Boot, Arnoud;
- Rozen, Steven G.
Publication type:
Article
mSigHdp: hierarchical Dirichlet process mixture modeling for mutational signature discovery.
Published in:
NAR Genomics & Bioinformatics, 2023, v. 5, n. 1, p. 1, doi. 10.1093/nargab/lqad005
By:
- Liu, Mo;
- Wu, Yang;
- Jiang, Nanhai;
- Boot, Arnoud;
- Rozen, Steven G
Publication type:
Article
Primer3—new capabilities and interfaces.
Published in:
Nucleic Acids Research, 2012, v. 40, n. 15, p. e115, doi. 10.1093/nar/gks596
By:
- Untergasser, Andreas;
- Cutcutache, Ioana;
- Koressaar, Triinu;
- Ye, Jian;
- Faircloth, Brant C.;
- Remm, Maido;
- Rozen, Steven G.
Publication type:
Article
Acetyl-CoA metabolism drives epigenome change and contributes to carcinogenesis risk in fatty liver disease.
Published in:
Genome Medicine, 2022, v. 14, n. 1, p. 1, doi. 10.1186/s13073-022-01071-5
By:
- Assante, Gabriella;
- Chandrasekaran, Sriram;
- Ng, Stanley;
- Tourna, Aikaterini;
- Chung, Carolina H.;
- Isse, Kowsar A.;
- Banks, Jasmine L.;
- Soffientini, Ugo;
- Filippi, Celine;
- Dhawan, Anil;
- Liu, Mo;
- Rozen, Steven G.;
- Hoare, Matthew;
- Campbell, Peter;
- Ballard, J. William O.;
- Turner, Nigel;
- Morris, Margaret J.;
- Chokshi, Shilpa;
- Youngson, Neil A.
Publication type:
Article
Exome sequencing identifies highly recurrent MED12 somatic mutations in breast fibroadenoma.
Published in:
Nature Genetics, 2014, v. 46, n. 8, p. 877, doi. 10.1038/ng.3037
By:
- Lim, Weng Khong;
- Ong, Choon Kiat;
- Tan, Jing;
- Thike, Aye Aye;
- Ng, Cedric Chuan Young;
- Rajasegaran, Vikneswari;
- Myint, Swe Swe;
- Nagarajan, Sanjanaa;
- Nasir, Nur Diyana Md;
- McPherson, John R;
- Cutcutache, Ioana;
- Poore, Gregory;
- Tay, Su Ting;
- Ooi, Wei Siong;
- Tan, Veronique Kiak Mien;
- Hartman, Mikael;
- Ong, Kong Wee;
- Tan, Benita K T;
- Rozen, Steven G;
- Tan, Puay Hoon
Publication type:
Article
Whole-exome sequencing studies of parathyroid carcinomas reveal novel PRUNE2 mutations, distinctive mutational spectra related to APOBEC-catalyzed DNA mutagenesis and mutational enrichment in kinases associated with cell migration and invasion.
Published in:
2015
By:
- Yu, Willie;
- McPherson, John R;
- Stevenson, Mark;
- van Eijk, Ronald;
- Heng, Hong Lee;
- Newey, Paul;
- Gan, Anna;
- Ruano, Dina;
- Huang, Dachuan;
- Poon, Song Ling;
- Ong, Choon Kiat;
- van Wezel, Tom;
- Cavaco, Branca;
- Rozen, Steven G;
- Tan, Patrick;
- Teh, Bin T;
- Thakker, Rajesh V;
- Morreau, Hans
Publication type:
journal article
Beyond fitness tracking: The use of consumer-grade wearable data from normal volunteers in cardiovascular and lipidomics research.
Published in:
PLoS Biology, 2018, v. 16, n. 2, p. 1, doi. 10.1371/journal.pbio.2004285
By:
- Lim, Weng Khong;
- Davila, Sonia;
- Teo, Jing Xian;
- Yang, Chengxi;
- Pua, Chee Jian;
- Blöcker, Christopher;
- Lim, Jing Quan;
- Ching, Jianhong;
- Yap, Jonathan Jiunn Liang;
- Tan, Swee Yaw;
- Sahlén, Anders;
- Chin, Calvin Woon-Loong;
- Teh, Bin Tean;
- Rozen, Steven G.;
- Cook, Stuart Alexander;
- Yeo, Khung Keong;
- Tan, Patrick
Publication type:
Article
Differentially Expressed miRNAs in Hepatocellular Carcinoma Target Genes in the Genetic Information Processing and Metabolism Pathways.
Published in:
Scientific Reports, 2016, p. 20065, doi. 10.1038/srep20065
By:
- Thurnherr, Thomas;
- Mah, Way-Champ;
- Lei, Zhengdeng;
- Jin, Yu;
- Rozen, Steven G.;
- Lee, Caroline G.
Publication type:
Article
MSIseq: Software for Assessing Microsatellite Instability from Catalogs of Somatic Mutations.
Published in:
Scientific Reports, 2015, p. 13321, doi. 10.1038/srep13321
By:
- Ni Huang, Mi;
- McPherson, John R.;
- Cutcutache, Ioana;
- Teh, Bin Tean;
- Tan, Patrick;
- Rozen, Steven G.
Publication type:
Article
Correction: Acetyl-CoA metabolism drives epigenome change and contributes to carcinogenesis risk in fatty liver disease.
Published in:
2023
By:
- Assante, Gabriella;
- Chandrasekaran, Sriram;
- Ng, Stanley;
- Tourna, Aikaterini;
- Chung, Carolina H.;
- Isse, Kowsar A.;
- Banks, Jasmine L.;
- Soffientini, Ugo;
- Filippi, Celine;
- Dhawan, Anil;
- Liu, Mo;
- Rozen, Steven G.;
- Hoare, Matthew;
- Campbell, Peter;
- Ballard, J. William O.;
- Turner, Nigel;
- Morris, Margaret J.;
- Chokshi, Shilpa;
- Youngson, Neil A.
Publication type:
Correction Notice
Functional genomics identifies specific vulnerabilities in PTEN-deficient breast cancer.
Published in:
2018
By:
- Yew Chung Tang;
- Szu-Chi Ho;
- Tan, Elisabeth;
- Ng, Alvin Wei Tian;
- McPherson, John R.;
- Goh, Germaine Yen Lin;
- Bin Tean Teh;
- Bard, Frederic;
- Rozen, Steven G.;
- Tang, Yew Chung;
- Ho, Szu-Chi;
- Teh, Bin Tean
Publication type:
journal article
Aristolochic acids and their derivatives are widely implicated in liver cancers in Taiwan and throughout Asia.
Published in:
Science Translational Medicine, 2017, v. 9, n. 412, p. 1, doi. 10.1126/scitranslmed.aan6446
By:
- Ng, Alvin W. T.;
- Song Ling Poon;
- Mi Ni Huang;
- Jing Quan Lim;
- Boot, Arnoud;
- Yu, Willie;
- Yuka Suzuki;
- Saranya Thangaraju;
- Ng, Cedric C. Y.;
- Tan, Patrick;
- See-Tong Pang;
- Hao-Yi Huang;
- Ming-Chin Yu;
- Po-Huang Lee;
- Sen-Yung Hsieh;
- Chang, Alex Y.;
- Bin T. Teh;
- Rozen, Steven G.
Publication type:
Article
Mutational processes in cancer preferentially affect binding of particular transcription factors.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-82910-0
By:
- Liu, Mo;
- Boot, Arnoud;
- Ng, Alvin W. T.;
- Gordân, Raluca;
- Rozen, Steven G.
Publication type:
Article
Enhancer-derived long non-coding RNAs CCAT1 and CCAT2 at rs6983267 has limited predictability for early stage colorectal carcinoma metastasis.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-020-79906-7
By:
- Thean, Lai Fun;
- Blöcker, Christopher;
- Li, Hui Hua;
- Lo, Michelle;
- Wong, Michelle;
- Tang, Choong Leong;
- Tan, Emile K. W.;
- Rozen, Steven G.;
- Cheah, Peh Yean
Publication type:
Article
Digital phenotyping by consumer wearables identifies sleep-associated markers of cardiovascular disease risk and biological aging.
Published in:
Communications Biology, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42003-019-0605-1
By:
- Teo, Jing Xian;
- Davila, Sonia;
- Yang, Chengxi;
- Hii, An An;
- Pua, Chee Jian;
- Yap, Jonathan;
- Tan, Swee Yaw;
- Sahlén, Anders;
- Chin, Calvin Woon-Loong;
- Teh, Bin Tean;
- Rozen, Steven G.;
- Cook, Stuart Alexander;
- Yeo, Khung Keong;
- Tan, Patrick;
- Lim, Weng Khong
Publication type:
Article
SigProfilerMatrixGenerator: a tool for visualizing and exploring patterns of small mutational events.
Published in:
BMC Genomics, 2019, v. 20, n. 1, p. N.PAG, doi. 10.1186/s12864-019-6041-2
By:
- Bergstrom, Erik N.;
- Huang, Mi Ni;
- Mahto, Uma;
- Barnes, Mark;
- Stratton, Michael R.;
- Rozen, Steven G.;
- Alexandrov, Ludmil B.
Publication type:
Article
Mutation signatures implicate aristolochic acid in bladder cancer development.
Published in:
Genome Medicine, 2015, v. 7, n. 1, p. 1, doi. 10.1186/s13073-015-0161-3
By:
- Song Ling Poon;
- Mi Ni Huang;
- Yang Choo;
- McPherson, John R.;
- Yu, Willie;
- Hong Lee Heng;
- Gan, Anna;
- Swe Swe Myint;
- Ee Yan Siew;
- Lian Dee Ler;
- Lay Guat Ng;
- Wen-Hui Weng;
- Cheng-Keng Chuang;
- Yuen, John S. P.;
- See-Tong Pang;
- Tan, Patrick;
- Bin Tean Teh;
- Rozen, Steven G.
Publication type:
Article
The mutational landscape of early‐ and typical‐onset oral tongue squamous cell carcinoma.
Published in:
Cancer (0008543X), 2021, v. 127, n. 4, p. 544, doi. 10.1002/cncr.33309
By:
- Campbell, Benjamin R.;
- Chen, Zhishan;
- Faden, Daniel L.;
- Agrawal, Nishant;
- Li, Ryan J.;
- Hanna, Glenn J.;
- Iyer, N. Gopalakrishna;
- Boot, Arnoud;
- Rozen, Steven G.;
- Vettore, Andre L.;
- Panda, Binay;
- Krishnan, Neeraja M.;
- Pickering, Curtis R.;
- Myers, Jeffrey N.;
- Guo, Xingyi;
- Lang Kuhs, Krystle A.
Publication type:
Article
Evaluation and optimisation of indel detection workflows for ion torrent sequencing of the BRCA1 and BRCA2 genes.
Published in:
BMC Genomics, 2014, v. 15, n. 1, p. 1, doi. 10.1186/1471-2164-15-516
By:
- Zhen Xuan Yeo;
- Joshua Chee Wong;
- Rozen, Steven G.;
- Lee, Ann Siew
Publication type:
Article
Multiregion ultra-deep sequencing reveals early intermixing and variable levels of intratumoral heterogeneity in colorectal cancer.
Published in:
Molecular Oncology, 2017, v. 11, n. 2, p. 124, doi. 10.1002/1878-0261.12012
By:
- Suzuki, Yuka;
- Ng, Sarah Boonhsi;
- Chua, Clarinda;
- Leow, Wei Qiang;
- Chng, Jermain;
- Liu, Shi Yang;
- Ramnarayanan, Kalpana;
- Gan, Anna;
- Ho, Dan Liang;
- Ten, Rachel;
- Su, Yan;
- Lezhava, Alexandar;
- Lai, Jiunn Herng;
- Koh, Dennis;
- Lim, Kiat Hon;
- Tan, Patrick;
- Rozen, Steven G.;
- Tan, Iain Beehuat
Publication type:
Article

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