Prediction of metabolic drug clearance in humans: In vitro–in vivo extrapolation vs allometric scaling.
- Published in:
- Xenobiotica, 2006, v. 36, n. 7, p. 567, doi. 10.1080/00498250600761662
- By:
- Publication type:
- Article
Works by Rowland-Yeo K
Results: 9
1
2
Prediction of in vivo drug clearance from in vitro data. II: Potential inter-ethnic differences.
- Published in:
- Xenobiotica, 2006, v. 36, n. 6, p. 499, doi. 10.1080/00498250600683262
- By:
- Publication type:
- Article
3
Prediction of in vivo drug clearance from in vitro data. I: Impact of inter-individual variability.
- Published in:
- Xenobiotica, 2006, v. 36, n. 6, p. 473, doi. 10.1080/00498250600683197
- By:
- Publication type:
- Article
4
Towards a Best Practice Approach in PBPK Modeling: Case Example of Developing a Unified Efavirenz Model Accounting for Induction of CYPs 3A4 and 2B6.
- Published in:
- CPT: Pharmacometrics & Systems Pharmacology, 2016, v. 5, n. 7, p. 367, doi. 10.1002/psp4.12088
- By:
- Publication type:
- Article
5
Basic Concepts in Physiologically Based Pharmacokinetic Modeling in Drug Discovery and Development.
- Published in:
- CPT: Pharmacometrics & Systems Pharmacology, 2013, v. 2, n. 8, p. 1, doi. 10.1038/psp.2013.41
- By:
- Publication type:
- Article
6
Evaluation of an In Silico PBPK Post-Bariatric Surgery Model through Simulating Oral Drug Bioavailability of Atorvastatin and Cyclosporine.
- Published in:
- CPT: Pharmacometrics & Systems Pharmacology, 2013, v. 2, n. 6, p. 1, doi. 10.1038/psp.2013.23
- By:
- Publication type:
- Article
7
A Mechanistic Framework for In Vitro-In Vivo Extrapolation of Liver Membrane Transporters: Prediction of Drug-Drug Interaction Between Rosuvastatin and Cyclosporine.
- Published in:
- Clinical Pharmacokinetics, 2014, v. 53, n. 1, p. 73, doi. 10.1007/s40262-013-0097-y
- By:
- Publication type:
- Article
8
Are there differences in the catalytic activity per unit enzyme of recombinantly expressed and human liver microsomal cytochrome P450 2C9? A systematic investigation into inter-system extrapolation factors.
- Published in:
- Biopharmaceutics & Drug Disposition, 2011, v. 32, n. 6, p. 303, doi. 10.1002/bdd.760
- By:
- Publication type:
- Article
9
Application of a systems approach to the bottom-up assessment of pharmacokinetics in obese patients: expected variations in clearance.
- Published in:
- 2011
- By:
- Publication type:
- journal article