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Long-Term Dupilumab Efficacy on Severe Exacerbations and Lung Function in Patients with Type 2 Asthma.
Published in:
Annals of the American Thoracic Society, 2024, v. 21, n. 4, p. 675, doi. 10.1513/AnnalsATS.202306-544RL
By:
- Papi, Alberto;
- Castro, Mario;
- Busse, William W.;
- Langton, David;
- Korn, Stephanie;
- Xia, Changming;
- Soler, Xavier;
- Pandit-Abid, Nami;
- Radwan, Amr;
- Jacob-Nara, Juby A.;
- Rowe, Paul J.;
- Deniz, Yamo
Publication type:
Article
Prevalence of type 2 inflammatory signatures and efficacy of dupilumab in patients with chronic rhinosinusitis with nasal polyps from two phase 3 clinical trials: SINUS‐24 and SINUS‐52.
Published in:
International Forum of Allergy & Rhinology, 2024, v. 14, n. 3, p. 668, doi. 10.1002/alr.23249
By:
- Bachert, Claus;
- Khan, Asif H.;
- Lee, Stella E.;
- Hopkins, Claire;
- Peters, Anju T.;
- Fokkens, Wytske;
- Praestgaard, Amy;
- Radwan, Amr;
- Nash, Scott;
- Jacob‐Nara, Juby A.;
- Deniz, Yamo;
- Rowe, Paul J.
Publication type:
Article
Dupilumab efficacy and biomarkers in chronic rhinosinusitis with nasal polyps: Association between dupilumab treatment effect on nasal polyp score and biomarkers of type 2 inflammation in patients with chronic rhinosinusitis with nasal polyps in the phase 3 SINUS‐24 and SINUS‐52 trials
Published in:
International Forum of Allergy & Rhinology, 2022, v. 12, n. 9, p. 1191, doi. 10.1002/alr.22964
By:
- Bachert, Claus;
- Corren, Jonathan;
- Lee, Stella E.;
- Zhang, Haixin;
- Harel, Sivan;
- Cunoosamy, Danen;
- Khan, Asif H.;
- Jacob‐Nara, Juby A.;
- Siddiqui, Shahid;
- Nash, Scott;
- Rowe, Paul J.;
- Deniz, Yamo
Publication type:
Article
Rapid and sustained effects of dupilumab in severe chronic rhinosinusitis with nasal polyps.
Published in:
International Forum of Allergy & Rhinology, 2022, v. 12, n. 7, p. 958, doi. 10.1002/alr.22944
By:
- Hellings, Peter W.;
- Peters, Anju T.;
- Chaker, Adam M.;
- Heffler, Enrico;
- Zhang, Haixin;
- Praestgaard, Amy;
- Nash, Scott;
- Khan, Asif H.;
- Siddiqui, Shahid;
- Jacob‐Nara, Juby A.;
- Rowe, Paul J.;
- Deniz, Yamo
Publication type:
Article
Targeting Type 2 Inflammation and Epithelial Alarmins in Chronic Obstructive Pulmonary Disease: A Biologics Outlook.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2023, v. 208, n. 4, p. 395, doi. 10.1164/rccm.202303-0455CI
By:
- Rabe, Klaus F.;
- Rennard, Stephen;
- Martinez, Fernando J.;
- Celli, Bartolome R.;
- Singh, Dave;
- Papi, Alberto;
- Bafadhel, Mona;
- Heble, Jigna;
- Radwan, Amr;
- Soler, Xavier;
- Nara, Juby A. Jacob;
- Deniz, Yamo;
- Rowe, Paul J.
Publication type:
Article
Baseline Systemic Oral Corticosteroid Use in Patients with Asthma Initiating Dupilumab Treatment in the Real World: From the RAPID Global Registry.
Published in:
Journal of Asthma & Allergy, 2024, v. 17, p. 551, doi. 10.2147/JAA.S451689
By:
- Lugogo, Nijra L;
- Heffler, Enrico;
- Plaza, Vicente;
- Hilberg, Ole;
- Xia, Changming;
- Nash, Scott;
- Pandit, Nami;
- Jacob-Nara, Juby A;
- Sacks, Harry J;
- Rowe, Paul J;
- Deniz, Yamo;
- Hardin, Megan;
- Soler, Xavier
Publication type:
Article
Impact of Exacerbation History on Dupilumab Efficacy in Children with Uncontrolled Moderate-to-Severe Asthma: LIBERTY ASTHMA VOYAGE Study.
Published in:
Journal of Asthma & Allergy, 2024, v. 17, p. 143, doi. 10.2147/JAA.S416292
By:
- Guilbert, Theresa W;
- Tolcachier, Alberto;
- Fiocchi, Alessandro G;
- Katelaris, Constance H;
- Phipatanakul, Wanda;
- Begin, Philippe;
- de Mir, Inés;
- Altincatal, Arman;
- Gall, Rebecca;
- Ledanois, Olivier;
- Radwan, Amr;
- Jacob-Nara, Juby A;
- Deniz, Yamo;
- Rowe, Paul J
Publication type:
Article
Impact of Lung Function on Asthma Exacerbation Rates in Children Treated with Dupilumab: The VOYAGE Study.
Published in:
Journal of Asthma & Allergy, 2024, v. 17, p. 81, doi. 10.2147/JAA.S425101
By:
- Guilbert, Theresa W;
- Murphy, Kevin R;
- Hamelmann, Eckard;
- Ross, Kristie R;
- Gupta, Atul;
- Fiocchi, Alessandro;
- Xia, Changming;
- Gall, Rebecca;
- Ledanois, Olivier;
- Radwan, Amr;
- Jacob-Nara, Juby A;
- Rowe, Paul J;
- Deniz, Yamo
Publication type:
Article
Dupilumab Reduces Asthma Disease Burden and Recurrent SCS Use in Patients with CRSwNP and Coexisting Asthma.
Published in:
Journal of Asthma & Allergy, 2024, v. 17, p. 1, doi. 10.2147/JAA.S420140
By:
- Gurnell, Mark;
- Radwan, Amr;
- Bachert, Claus;
- Lugogo, Njira;
- Cho, Seong H;
- Nash, Scott;
- Zhang, Haixin;
- Khan, Asif H;
- Jacob-Nara, Juby A;
- Rowe, Paul J;
- Deniz, Yamo
Publication type:
Article
Health-Related Quality of Life Impairment Among Patients with Severe Chronic Rhinosinusitis with Nasal Polyps in the SINUS-24 Trial.
Published in:
Journal of Asthma & Allergy, 2023, v. 16, p. 323, doi. 10.2147/JAA.S372598
By:
- Maspero, Jorge F;
- Khan, Asif H;
- Philpott, Carl;
- Hellings, Peter W;
- Hopkins, Claire;
- Wagenmann, Martin;
- Siddiqui, Shahid;
- Msihid, Jérôme;
- Nash, Scott;
- Chuang, Chien-Chia;
- Kamat, Siddhesh;
- Rowe, Paul J;
- Deniz, Yamo;
- Jacob-Nara, Juby A
Publication type:
Article
Dupilumab Efficacy in Patients with Uncontrolled Moderate-to-Severe Type 2 Asthma Regardless of Perennial Aeroallergen Sensitization.
Published in:
Journal of Asthma & Allergy, 2023, v. 16, p. 249, doi. 10.2147/JAA.S385645
By:
- Corren, Jonathan;
- Jackson, David J;
- Casale, Thomas B;
- Borish, Larry;
- Rabe, Klaus F;
- Busse, William W;
- Maspero, Jorge F;
- Jackson, Daniel J;
- Daizadeh, Nadia;
- Altincatal, Arman;
- Radwan, Amr;
- Khodzhayev, Angela;
- Djandji, Michel;
- Jacob-Nara, Juby A;
- Rowe, Paul J;
- Deniz, Yamo
Publication type:
Article
Impact of Baseline Lung Function on Future Exacerbations in Patients with Moderate-to-Severe Asthma.
Published in:
Journal of Asthma & Allergy, 2022, v. 15, p. 1639, doi. 10.2147/JAA.S375134
By:
- Khan, Asif H;
- Gray, Cori;
- Eckert, Laurent;
- Amand, Caroline;
- Maroni, Jaman;
- Wang, Zhixiao;
- Jones, Bethan;
- Berni, Thomas;
- Morgan, Christopher Ll;
- Rowe, Paul J
Publication type:
Article
Improvement in Health-Related Quality of Life with Dupilumab in Patients with Moderate-to-Severe Asthma with Comorbid Chronic Rhinosinusitis with/without Nasal Polyps: An Analysis of the QUEST Study.
Published in:
Journal of Asthma & Allergy, 2022, v. 15, p. 767, doi. 10.2147/JAA.S363527
By:
- Hopkins, Claire;
- Buchheit, Kathleen M;
- Heffler, Enrico;
- Cohen, Noam A;
- Olze, Heidi;
- Khan, Asif H;
- Msihid, Jérôme;
- Siddiqui, Shahid;
- Nash, Scott;
- Jacob-Nara, Juby A;
- Rowe, Paul J;
- Deniz, Yamo
Publication type:
Article
Rapid and Continuing Improvements in Nasal Symptoms with Dupilumab in Patients with Severe CRSwNP.
Published in:
Journal of Asthma & Allergy, 2022, v. 15, p. 557, doi. 10.2147/JAA.S355391
By:
- Bachert, Claus;
- Khan, Asif H;
- Hopkins, Claire;
- Blaiss, Michael S;
- Soler, Zachary M;
- Nash, Scott;
- Siddiqui, Shahid;
- Praestgaard, Amy;
- Deniz, Yamo;
- Rowe, Paul J;
- Jacob-Nara, Juby A
Publication type:
Article
Improvement in Lung Function with Dupilumab Does Not Predict Its Effects on Reducing Asthma Exacerbation.
Published in:
Journal of Asthma & Allergy, 2022, v. 15, p. 851, doi. 10.2147/JAA.S354013
By:
- Hanania, Nicola A;
- Maspero, Jorge F;
- Halpin, David MG;
- Jackson, David J;
- Panettieri, Reynold A;
- Castro, Mario;
- Domingo, Christian;
- Daizadeh, Nadia;
- Gall, Rebecca;
- Jacob-Nara, Juby A;
- Ortiz, Benjamin;
- Djandji, Michel;
- Rowe, Paul J;
- Deniz, Yamo
Publication type:
Article
Association Between a Type 2 Inflammatory Disease Burden Score and Outcomes Among Patients with Asthma.
Published in:
Journal of Asthma & Allergy, 2021, v. 14, p. 1173, doi. 10.2147/JAA.S321212
By:
- Price, David;
- Menzies-Gow, Andrew;
- Bachert, Claus;
- Canonica, Giorgio Walter;
- Kocks, Janwillem;
- Khan, Asif H;
- Ye, Fen;
- Rowe, Paul J;
- Lu, Yufang;
- Kamat, Siddhesh;
- Carter, Victoria;
- Voorham, Jaco
Publication type:
Article
Dupilumab efficacy in patients with chronic rhinosinusitis with nasal polyps with and without allergic rhinitis.
Published in:
Allergy & Asthma Proceedings, 2023, v. 44, n. 4, p. 265, doi. 10.2500/aap.2023.44.230015
By:
- Peters, Anju T.;
- Wagenmann, Martin;
- Bernstein, Jonathan A.;
- Khan, Asif H.;
- Nash, Scott;
- Jacob-Nara, Juby A.;
- Siddiqui, Shahid;
- Rowe, Paul J.;
- Deniz, Yamo
Publication type:
Article
Rapid and Sustained Improvement in Sense of Smell With Dupilumab in Patients With Severe Chronic Rhinosinusitis With Nasal Polyps and 0, 1, 2, or ≥3 Prior Sinonasal Surgeries (SNS): Pooled Results From the SINUS-24 and SINUS-52 Phase 3 Studies.
Published in:
Rhinology Supplement, 2021, v. 61, p. 587
By:
- Mullol, Joaquim;
- Bachert, Claus;
- Desrosiers, Martin;
- Han, Joseph K.;
- Jankowski, Roger;
- Daizadeh, Nadia;
- Ortiz, Benjamin;
- Siddiqui, Shahid;
- Djandji, Michel;
- Jacob-Nara, Juby A.;
- Rowe, Paul J.;
- Deniz, Yamo;
- Amin, Nikhil;
- Mannent, Leda P.;
- Khan, Asif H.;
- Kamat, Siddhesh
Publication type:
Article
Dupilumab Improved All Smell Outcomes in Patients With Severe Chronic Rhinosinusitis With Nasal Polyps Regardless of Asthma or NSAID-Exacerbated Respiratory Disease Status: Results From the SINUS-24 and SINUS-52 Phase 3 Trials.
Published in:
Rhinology Supplement, 2021, v. 61, p. 586
By:
- Mullol, Joaquim;
- Bachert, Claus;
- Hellings, Peter W.;
- Daizadeh, Nadia;
- Ortiz, Benjamin;
- Djandji, Michel;
- Deniz, Yamo;
- Rowe, Paul J.;
- Amin, Nikhil;
- Mannent, Leda P.
Publication type:
Article
The prevalence of type 2 inflammatory signatures in patients with chronic rhinosinusitis with nasal polyps from two phase 3 clinical trials, SINUS-24 and SINUS-52.
Published in:
Rhinology Supplement, 2021, v. 61, p. 351
By:
- Bachert, Claus;
- Lee, Stella E.;
- Hopkins, Claire;
- Peters, Anju T.;
- Fokkens, Wytske;
- Khan, Asif H.;
- Praestgaard, Amy;
- Siddiqui, Shahid;
- Nash, Scott;
- Jacob-Nara, Juby A.;
- Deniz, Yamo;
- Rowe, Paul J.
Publication type:
Article
Impact of Dupilumab on Sinonasal Symptoms and Outcomes in Severe Chronic Rhinosinusitis With Nasal Polyps.
Published in:
Otolaryngology-Head & Neck Surgery, 2024, v. 170, n. 4, p. 1173, doi. 10.1002/ohn.627
By:
- Hopkins, Claire;
- Mullol, Joaquim;
- Khan, Asif H.;
- Lee, Stella E.;
- Wagenmann, Martin;
- Hellings, Peter;
- Fokkens, Wytske;
- Msihid, Jérôme;
- Nair, Radhika;
- Kamat, Siddhesh;
- Nash, Scott;
- Radwan, Amr;
- Jacob‐Nara, Juby A.;
- Deniz, Yamo;
- Rowe, Paul J.
Publication type:
Article
Dupilumab Efficacy in Patients with Type 2 Asthma with and without Elevated Blood Neutrophils.
Published in:
Journal of Immunology Research, 2023, p. 1, doi. 10.1155/2023/9943584
By:
- Bleecker, Eugene R.;
- Panettieri Jr., Reynold A.;
- Lugogo, Njira L.;
- Corren, Jonathan;
- Daizadeh, Nadia;
- Jacob-Nara, Juby A.;
- Deniz, Yamo;
- Rowe, Paul J.;
- Khodzhayev, Angela;
- Soler, Xavier;
- Ferro, Thomas J.;
- Hansen, Christopher N.
Publication type:
Article
Dupilumab improves outcomes in patients with chronic rhinosinusitis with nasal polyps irrespective of gender: results from the SINUS‐52 trial.
Published in:
Clinical & Translational Immunology, 2024, v. 13, n. 6, p. 1, doi. 10.1002/cti2.1511
By:
- Fokkens, Wytske J;
- Bachert, Claus;
- Hopkins, Claire;
- Marglani, Osama;
- Praestgaard, Amy;
- Nash, Scott;
- Deniz, Yamo;
- Rowe, Paul J;
- Sacks, Harry;
- Jacob‐Nara, Juby A
Publication type:
Article
Efficacy of dupilumab in patients with uncontrolled, moderate‐to‐severe asthma with fungal sensitization.
Published in:
Clinical & Experimental Allergy, 2023, v. 53, n. 10, p. 1020, doi. 10.1111/cea.14389
By:
- Corren, Jonathan;
- Hanania, Nicola A.;
- Busse, William W.;
- Sher, Lawrence D.;
- Altincatal, Arman;
- Hardin, Megan;
- Mannent, Leda P.;
- Amin, Nikhil;
- Lederer, David J.;
- Soler, Xavier;
- Jacob‐Nara, Juby A.;
- Rowe, Paul J.;
- Deniz, Yamo
Publication type:
Article
Responder analysis to demonstrate the effect of targeting type 2 inflammatory mechanisms with dupilumab across objective and patient‐reported endpoints for patients with severe chronic rhinosinusitis with nasal polyps in the SINUS‐24 and SINUS‐52 studies
Published in:
Clinical & Experimental Allergy, 2022, v. 52, n. 2, p. 244, doi. 10.1111/cea.14051
By:
- Bachert, Claus;
- Peters, Anju T.;
- Heffler, Enrico;
- Han, Joseph K.;
- Olze, Heidi;
- Pfaar, Oliver;
- Chuang, Chien‐Chia;
- Rout, Raj;
- Attre, Richa;
- Goga, Ledia;
- Jacob‐Nara, Juby A.;
- Rowe, Paul J.;
- Deniz, Yamo;
- Chen, Zhen;
- Kamat, Siddhesh;
- Siddiqui, Shahid
Publication type:
Article
Dupilumab sustains efficacy in patients with moderate‐to‐severe type 2 asthma regardless of inhaled corticosteroids dose.
Published in:
Allergy, 2023, v. 78, n. 11, p. 2921, doi. 10.1111/all.15792
By:
- Pavord, Ian D.;
- Bourdin, Arnaud;
- Papi, Alberto;
- Domingo, Christian;
- Corren, Jonathan;
- Altincatal, Arman;
- Radwan, Amr;
- Pandit‐Abid, Nami;
- Jacob‐Nara, Juby A.;
- Deniz, Yamo;
- Rowe, Paul J.;
- Laws, Elizabeth;
- Lederer, David J.;
- Hardin, Megan
Publication type:
Article
Dupilumab improves long‐term outcomes in patients with uncontrolled, moderate‐to‐severe GINA‐based type 2 asthma, irrespective of allergic status.
Published in:
Allergy, 2023, v. 78, n. 8, p. 2148, doi. 10.1111/all.15747
By:
- Rabe, Klaus F.;
- Pavord, Ian D.;
- Busse, William W.;
- Chupp, Geoffrey L.;
- Izuhara, Kenji;
- Altincatal, Arman;
- Gall, Rebecca;
- Pandit‐Abid, Nami;
- Deniz, Yamo;
- Rowe, Paul J.;
- Jacob‐Nara, Juby A.;
- Radwan, Amr
Publication type:
Article
Assessment of dupilumab in children with moderate‐to‐severe type 2 asthma with or without evidence of allergic asthma.
Published in:
Allergy, 2023, v. 78, n. 8, p. 2157, doi. 10.1111/all.15743
By:
- Papadopoulos, Nikolaos G.;
- Szefler, Stanley J.;
- Bacharier, Leonard B.;
- Maspero, Jorge F.;
- Domingo, Christian;
- Fiocchi, Alessandro;
- Lee, Jason K.;
- Daizadeh, Nadia;
- Lederer, David J.;
- Hardin, Megan;
- Gall, Rebecca;
- Djandji, Michel;
- Siddiqui, Shahid;
- Jacob‐Nara, Juby A.;
- Deniz, Yamo;
- Rowe, Paul J.
Publication type:
Article
Dupilumab reduced impact of severe exacerbations on lung function in patients with moderate‐to‐severe type 2 asthma.
Published in:
Allergy, 2023, v. 78, n. 1, p. 233, doi. 10.1111/all.15456
By:
- Papi, Alberto;
- Corren, Jonathan;
- Castro, Mario;
- Domingo, Christian;
- Rogers, Linda;
- Chapman, Kenneth R.;
- Jackson, Daniel J.;
- Daizadeh, Nadia;
- Pandit‐Abid, Nami;
- Gall, Rebecca;
- Jacob‐Nara, Juby A.;
- Rowe, Paul J.;
- Deniz, Yamo;
- Ortiz, Benjamin
Publication type:
Article
Dupilumab efficacy in adolescents with uncontrolled, moderate‐to‐severe asthma: LIBERTY ASTHMA QUEST.
Published in:
Allergy, 2021, v. 76, n. 8, p. 2621, doi. 10.1111/all.14872
By:
- Maspero, Jorge F.;
- FitzGerald, John Mark;
- Pavord, Ian D.;
- Rice, Megan S.;
- Maroni, Jaman;
- Rowe, Paul J.;
- Pirozzi, Gianluca;
- Amin, Nikhil;
- Ruddy, Marcella;
- Graham, Neil M. H.;
- Teper, Ariel;
- Hardin, Megan
Publication type:
Article
Validation of SOFIT for Measuring Physical Activity of First- to Eighth-Grade Students.
Published in:
Pediatric Exercise Science, 1997, v. 9, n. 2, p. 136, doi. 10.1123/pes.9.2.136
By:
- Rowe, Paul J.;
- Schuldheisz, Joel M.;
- van der Mars, Hans
Publication type:
Article
Long-term efficacy of dupilumab in severe asthma by baseline oral corticosteroid dose.
Published in:
ERJ Open Research, 2023, v. 9, n. 6, p. 1, doi. 10.1183/23120541.00056-2023
By:
- Domingo, Christian;
- Rabe, Klaus F.;
- Price, David;
- Brusselle, Guy;
- Wechsler, Michael E.;
- Changming Xia;
- Pandit-Abid, Nami;
- Gall, Rebecca;
- Rowe, Paul J.;
- Deniz, Yamo;
- Jacob-Nara, Juby A.;
- Radwan, Amr
Publication type:
Article

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