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The BACE‐1 inhibitor CNP520 for prevention trials in Alzheimer's disease.
Published in:
EMBO Molecular Medicine, 2018, v. 10, n. 11, p. N.PAG, doi. 10.15252/emmm.201809316
By:
- Neumann, Ulf;
- Ufer, Mike;
- Jacobson, Laura H;
- Rouzade‐Dominguez, Marie‐Laure;
- Huledal, Gunilla;
- Kolly, Carine;
- Lüönd, Rainer M;
- Machauer, Rainer;
- Veenstra, Siem J;
- Hurth, Konstanze;
- Rueeger, Heinrich;
- Tintelnot‐Blomley, Marina;
- Staufenbiel, Matthias;
- Shimshek, Derya R;
- Perrot, Ludovic;
- Frieauff, Wilfried;
- Dubost, Valerie;
- Schiller, Hilmar;
- Vogg, Barbara;
- Beltz, Karen
Publication type:
Article
The API Generation program: Biomarker phenotyping of cognitively unimpaired participants screened in Generation study 1 and Generation study 2: Alzheimer's Prevention Initiative (API) Generation program: Baseline characteristics and umibecestat results during treatment and follow‐up
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.041143
By:
- Rouzade‐Dominguez, Marie‐Laure;
- Riviere, Marie‐Emmanuelle;
- Borowsky, Beth;
- Liu, Fonda;
- Cazorla, Pilar;
- Quinn, Matt;
- Seneca, Nicholas;
- Neumann, Ulf;
- Eichenlaub, Udo;
- Chien, Yuchen;
- Viglietta, Vissia;
- Reiman, Eric M.;
- Sui, Yihan;
- Caputo, Angelika;
- Graf, Ana
Publication type:
Article
The API Generation program: Umibecestat treatment and discontinuation effects on hippocampal and whole brain volumes in the overall population and amyloid‐negative APOE4 homozygotes: Alzheimer's Prevention Initiative (API) Generation program: Baseline characteristics and umibecestat results during treatment and follow‐up
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.041142
By:
- Reiman, Eric M.;
- Tariot, Pierre N.;
- Borowsky, Beth;
- Liu, Fonda;
- Riviere, Marie‐Emmanuelle;
- Rouzade‐Dominguez, Marie‐Laure;
- Cazorla, Pilar;
- Quinn, Matt;
- Ricart, Javier;
- Langbaum, Jessica B.;
- Viglietta, Vissia;
- Sui, Yihan;
- Caputo, Angelika;
- Graf, Ana;
- Seneca, Nicholas;
- Neumann, Ulf;
- Eichenlaub, Udo;
- Chien, Yuchen;
- Arkuszewski, Michal;
- Piccard, Hernan
Publication type:
Article
Umibecestat in the API Generation program: Worsening in RBANS and/or CDR on treatment reverses after wash‐out: Alzheimer's Prevention Initiative (API) Generation program: Baseline characteristics and umibecestat results during treatment and follow‐up
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.041140
By:
- Graf, Ana;
- Riviere, Marie‐Emmanuelle;
- Liu, Fonda;
- Rouzade‐Dominguez, Marie‐Laure;
- Cazorla, Pilar;
- Quinn, Matt;
- Arkuszewski, Michal;
- Ricart, Javier;
- Langbaum, Jessica B.;
- Piccard, Hernan;
- Sui, Yihan;
- Quarg, Peter;
- Caputo, Angelika;
- Reiman, Eric M.;
- Tariot, Pierre N.
Publication type:
Article
The Generation program: Baseline characteristics of cognitively unimpaired APOE4 carriers recruited for Generation study 1 and Generation study 2: Alzheimer's Prevention Initiative (API) Generation program: Baseline characteristics and umibecestat results during treatment and follow‐up
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.041139
By:
- Tariot, Pierre N.;
- Borowsky, Beth;
- Liu, Fonda;
- Riviere, Marie‐Emmanuelle;
- Rouzade‐Dominguez, Marie‐Laure;
- Cazorla, Pilar;
- Quinn, Matt;
- Ricart, Javier;
- Langbaum, Jessica B.;
- Viglietta, Vissia;
- Sui, Yihan;
- Caputo, Angelika;
- Reiman, Eric M.;
- Graf, Ana
Publication type:
Article
FTS3‐01‐01: UMIBECESTAT (CNP520) IS NOT ASSOCIATED WITH CHANGES IN HIPPOCAMPAL MORPHOLOGY IN RATS OR CHANGES IN CSF AD BIOMARKERS IN HUMANS TREATED FOR 3 MONTHS.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P872, doi. 10.1016/j.jalz.2019.06.4618
By:
- Graf, Ana;
- Kolly, Carine;
- Dubost, Valerie;
- Vassar, Robert J.;
- Portelius, Erik;
- Höglund, Kina;
- Blennow, Kaj;
- Rouzade-Dominguez, Marie-Laure;
- Pezous, Nicole;
- Kretz, Sandrine;
- Vormfelde, Stefan Viktor;
- Neumann, Ulf
Publication type:
Article
RESULTS FROM A 3-MONTH STUDY IN HEALTHY SUBJECTS AGED 60 YEARS WITH THE BACE INHIBITOR CNP520.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P256, doi. 10.1016/j.jalz.2017.06.118
By:
- Ufer, Mike;
- Rouzade-Dominguez, Marie-Laure;
- Huledal, Gunilla;
- Pezous, Nicole;
- Graf, Ana;
- Lopez-Lopez, Cristina;
- Neumann, Ulf;
- Vormfelde, Stefan Viktor;
- Legangneux, Eric
Publication type:
Article
RATIONALE FOR CNP520 DOSE SELECTION FOR THE PIVOTAL CLINICAL PROGRAM IN PRECLINICAL AD.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P601, doi. 10.1016/j.jalz.2017.07.245
By:
- Lopez-Lopez, Cristina;
- Ufer, Mike;
- Rouzade-Dominguez, Marie-Laure;
- Pezous, Nicole;
- David, Olivier;
- Kolly, Carine;
- Tariot, Pierre;
- Reiman, Eric M.;
- Vargas, Gabriel;
- Lenz, Robert;
- Graf, Ana;
- Neumann, Ulf
Publication type:
Article
RESULTS FROM A FIRST-IN-HUMAN STUDY WITH THE BACE INHIBITOR CNP520.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P200, doi. 10.1016/j.jalz.2016.06.351
By:
- Ufer, Mike;
- Rouzade-Dominguez, Marie-Laure;
- Huledal, Gunilla;
- Pezous, Nicole;
- Avrameas, Alexandre;
- David, Olivier;
- Kretz, Sandrine;
- Kucher, Klaus;
- Neumann, Ulf;
- Cha, Jang-Ho;
- Graf, Ana;
- Lopez-Lopez, Cristina
Publication type:
Article
The Alzheimer's Prevention Initiative Generation Program: Study design of two randomized controlled trials for individuals at risk for clinical onset of Alzheimer's disease.
Published in:
Alzheimer's & Dementia: Translational Research & Clinical Interventions, 2019, v. 5, n. 1, p. 216, doi. 10.1016/j.trci.2019.02.005
By:
- Lopez Lopez, Cristina;
- Tariot, Pierre N.;
- Caputo, Angelika;
- Langbaum, Jessica B.;
- Liu, Fonda;
- Riviere, Marie‐Emmanuelle;
- Langlois, Carolyn;
- Rouzade‐Dominguez, Marie‐Laure;
- Zalesak, Martin;
- Hendrix, Suzanne;
- Thomas, Ronald G.;
- Viglietta, Vissia;
- Lenz, Rob;
- Ryan, J. Michael;
- Graf, Ana;
- Reiman, Eric M.
Publication type:
Article
Central representation of bladder and colon revealed by dual transsynaptic tracing in the rat: substrates for pelvic visceral coordination.
Published in:
European Journal of Neuroscience, 2003, v. 18, n. 12, p. 3311, doi. 10.1111/j.1460-9568.2003.03071.x
By:
- Rouzade‐Dominguez, Marie‐Laure;
- Miselis, Richard;
- Valentino, Rita J.
Publication type:
Article
Convergent responses of Barrington's nucleus neurons to pelvic visceral stimuli in the rat: a juxtacellular labelling study.
Published in:
European Journal of Neuroscience, 2003, v. 18, n. 12, p. 3325, doi. 10.1111/j.1460-9568.2003.03072.x
By:
- Rouzade‐Dominguez, Marie‐Laure;
- Pernar, Luise;
- Beck, Sheryl;
- Valentino, Rita J.
Publication type:
Article
A randomized, placebo-controlled trial of AFQ056 for the treatment of chorea in Huntington's disease.
Published in:
Movement Disorders, 2015, v. 30, n. 3, p. 427, doi. 10.1002/mds.26174
By:
- Reilmann, Ralf;
- Rouzade‐Dominguez, Marie‐Laure;
- Saft, Carsten;
- Süssmuth, Sigurd D.;
- Priller, Josef;
- Rosser, Anne;
- Rickards, Hugh;
- Schöls, Ludger;
- Pezous, Nicole;
- Gasparini, Fabrizio;
- Johns, Donald;
- Landwehrmeyer, Georg Bernhard;
- Gomez‐Mancilla, Baltazar
Publication type:
Article

Found: 13