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Single cell transcriptomes and multiscale networks from persons with and without Alzheimer's disease.
- Published in:
- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-49790-0
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- Publication type:
- Article
470 Associations with gene-transcript expressions in cocaine use disorder reveal genetic predispositions with other substance use and cardio-neurovascular disease.
- Published in:
- 2024
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- Publication type:
- Abstract
Transcriptomic profiling of prefrontal cortex reveals shared mechanisms underlying Alzheimer's and Parkinson's Diseases.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.075092
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- Article
Unraveling the transcriptomic landscape of healthy aging.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.075833
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- Publication type:
- Article
Unraveling the transcriptomic landscape of healthy aging.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.075833
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- Publication type:
- Article
Lineage specific 3D genome structure in the adult human brain and neurodevelopmental changes in the chromatin interactome.
- Published in:
- Nucleic Acids Research, 2023, v. 51, n. 20, p. 11142, doi. 10.1093/nar/gkad798
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- Publication type:
- Article
DeepGAMI: deep biologically guided auxiliary learning for multimodal integration and imputation to improve genotype–phenotype prediction.
- Published in:
- Genome Medicine, 2023, v. 15, n. 1, p. 1, doi. 10.1186/s13073-023-01248-6
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- Publication type:
- Article
Multi-omic atlas of the parahippocampal gyrus in Alzheimer's disease.
- Published in:
- Scientific Data, 2023, v. 10, n. 1, p. 1, doi. 10.1038/s41597-023-02507-2
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- Publication type:
- Article
Genome‐wide methylomic regulation of multiscale gene networks in Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 8, p. 3472, doi. 10.1002/alz.12969
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- Publication type:
- Article
Neuronal, glial and microglial maps of epigenetic and transcriptomics dysregulations in Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.060964
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- Publication type:
- Article
Basal forebrain cholinergic neurons are vulnerable in a mouse model of Down syndrome and their molecular fingerprint is rescued by maternal choline supplementation.
- Published in:
- FASEB Journal, 2023, v. 37, n. 6, p. 1, doi. 10.1096/fj.202202111RR
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- Publication type:
- Article
A Million Veteran Program GWAS of Alzheimer's Disease and Related Dementias in African Americans Identifies Multiple Genome‐Wide Significant Dementia Risk Loci.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 4, p. 1, doi. 10.1002/alz.063860
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- Publication type:
- Article
Rescue of deficits by Brwd1 copy number restoration in the Ts65Dn mouse model of Down syndrome.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-34200-0
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- Publication type:
- Article
Transcriptome-wide association study in UK Biobank Europeans identifies associations with blood cell traits.
- Published in:
- Human Molecular Genetics, 2022, v. 31, n. 14, p. 2333, doi. 10.1093/hmg/ddac011
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- Publication type:
- Article
Engagement of vascular early response genes typifies mild cognitive impairment.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 7, p. 1357, doi. 10.1002/alz.12481
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- Publication type:
- Article
Correction to: Profiling Basal Forebrain Cholinergic Neurons Reveals a Molecular Basis for Vulnerability Within the Ts65Dn Model of Down Syndrome and Alzheimer's Disease.
- Published in:
- 2022
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- Correction Notice
Use of the PsycheMERGE Network to Investigate the Association Between Depression Polygenic Scores and White Blood Cell Count.
- Published in:
- 2021
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- Publication type:
- journal article
Unbiased identification of novel transcription factors in striatal compartmentation and striosome maturation.
- Published in:
- eLife, 2021, p. 1, doi. 10.7554/eLife.65979
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- Publication type:
- Article
Profiling Basal Forebrain Cholinergic Neurons Reveals a Molecular Basis for Vulnerability Within the Ts65Dn Model of Down Syndrome and Alzheimer's Disease.
- Published in:
- Molecular Neurobiology, 2021, v. 58, n. 10, p. 5141, doi. 10.1007/s12035-021-02453-3
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- Publication type:
- Article
Author Correction: Brain Cell Type Specific Gene Expression and Co-expression Network Architectures.
- Published in:
- 2021
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- Publication type:
- Correction Notice
Association between genes regulating neural pathways for quantitative traits of speech and language disorders.
- Published in:
- NPJ Genomic Medicine, 2021, v. 6, n. 1, p. 1, doi. 10.1038/s41525-021-00225-5
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- Publication type:
- Article
Integration of Alzheimer's disease genetics and myeloid genomics identifies disease risk regulatory elements and genes.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-21823-y
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- Publication type:
- Article
Dream: powerful differential expression analysis for repeated measures designs.
- Published in:
- Bioinformatics, 2021, v. 37, n. 2, p. 192, doi. 10.1093/bioinformatics/btaa687
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- Publication type:
- Article
Genetic studies of Alzheimer's disease risk implicate clearance of lipid rich debris in myeloid cells: Lipids in AD and FTD: From genes to interventions.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.040601
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- Publication type:
- Article
Integration of Alzheimer's disease genetics and myeloid genomics reveals novel disease risk mechanisms: Functionalizing genetic variants in Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043897
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- Publication type:
- Article
Common schizophrenia risk variants are enriched in open chromatin regions of human glutamatergic neurons.
- Published in:
- Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-19319-2
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- Publication type:
- Article
Differential gene regulatory pattern in the human brain from schizophrenia using transcriptomic-causal network.
- Published in:
- BMC Bioinformatics, 2020, v. 21, n. 1, p. N.PAG, doi. 10.1186/s12859-020-03753-6
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- Publication type:
- Article
Chromatin accessibility mapping of the striatum identifies tyrosine kinase FYN as a therapeutic target for heroin use disorder.
- Published in:
- Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-18114-3
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- Publication type:
- Article
decorate: differential epigenetic correlation test.
- Published in:
- Bioinformatics, 2020, v. 36, n. 9, p. 2856, doi. 10.1093/bioinformatics/btaa067
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- Publication type:
- Article
Comparison of brain connectomes by MRI and genomics and its implication in Alzheimer's disease.
- Published in:
- 2020
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- Publication type:
- journal article
Functional interpretation of genetic variants using deep learning predicts impact on chromatin accessibility and histone modification.
- Published in:
- Nucleic Acids Research, 2019, v. 47, n. 20, p. 10597, doi. 10.1093/nar/gkz808
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- Publication type:
- Article
Integrative transcriptome imputation reveals tissue-specific and shared biological mechanisms mediating susceptibility to complex traits.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-11874-7
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- Publication type:
- Article
Assessment of somatic single-nucleotide variation in brain tissue of cases with schizophrenia.
- Published in:
- Translational Psychiatry, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41398-018-0342-0
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- Publication type:
- Article
Multi-Trait Analysis of GWAS and Biological Insights Into Cognition: A Response to Hill (2018).
- Published in:
- 2018
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- Publication type:
- journal article
Evaluation of chromatin accessibility in prefrontal cortex of individuals with schizophrenia.
- Published in:
- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-05379-y
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- Publication type:
- Article
Dimensional Traits of Schizotypy Associated With Glycine Receptor GLRA1 Polymorphism: An Exploratory Candidate-Gene Association Study.
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- Journal of Personality Disorders, 2018, v. 32, n. 3, p. 421, doi. 10.1521/pedi_2017_31_303
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- Publication type:
- Article
THC exposure of human iPSC neurons impacts genes associated with neuropsychiatric disorders.
- Published in:
- Translational Psychiatry, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41398-018-0137-3
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- Publication type:
- Article
Stress-Dependent Association Between Polygenic Risk for Schizophrenia and Schizotypal Traits in Young Army Recruits.
- Published in:
- Schizophrenia Bulletin, 2018, v. 44, n. 2, p. 338, doi. 10.1093/schbul/sbx074
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- Publication type:
- Article
minepath.org: a free interactive pathway analysis web server.
- Published in:
- Nucleic Acids Research, 2017, v. 45, n. W1, p. W116, doi. 10.1093/nar/gkx278
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- Publication type:
- Article
Open chromatin profiling of human postmortem brain infers functional roles for non-coding schizophrenia loci.
- Published in:
- Human Molecular Genetics, 2017, v. 26, n. 10, p. 1942, doi. 10.1093/hmg/ddx103
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- Publication type:
- Article
Integrative network analysis of nineteen brain regions identifies molecular signatures and networks underlying selective regional vulnerability to Alzheimer's disease.
- Published in:
- Genome Medicine, 2016, v. 8, p. 1, doi. 10.1186/s13073-016-0355-3
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- Publication type:
- Article
Activity-Dependent Changes in Gene Expression in Schizophrenia Human-Induced Pluripotent Stem Cell Neurons.
- Published in:
- 2016
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- Publication type:
- journal article
ACCELERATING MEDICINES PARTNERSHIP: CO-EXPRESSION NETWORKS.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P322, doi. 10.1016/j.jalz.2016.06.586
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- Publication type:
- Article
Substantial DNA methylation differences between two major neuronal subtypes in human brain.
- Published in:
- Nucleic Acids Research, 2016, v. 44, n. 6, p. 2593, doi. 10.1093/nar/gkv1304
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- Publication type:
- Article
Analyzing the Role of MicroRNAs in Schizophrenia in the Context of Common Genetic Risk Variants.
- Published in:
- 2016
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- Publication type:
- journal article
Genome-wide12 DNA methylation profiling in the superior temporal gyrus reveals epigenetic signatures associated with Alzheimer's disease.
- Published in:
- Genome Medicine, 2016, v. 8, p. 1, doi. 10.1186/s13073-015-0258-8
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- Publication type:
- Article
The Role of H3K4me3 in Transcriptional Regulation Is Altered in Huntington’s Disease.
- Published in:
- PLoS ONE, 2015, v. 10, n. 12, p. 1, doi. 10.1371/journal.pone.0144398
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- Publication type:
- Article
Disproportionate Contributions of Select Genomic Compartments and Cell Types to Genetic Risk for Coronary Artery Disease.
- Published in:
- PLoS Genetics, 2015, v. 11, n. 10, p. 1, doi. 10.1371/journal.pgen.1005622
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- Publication type:
- Article
The triggering receptor expressed on myeloid cells 2 (TREM2) is associated with enhanced inflammation, neuropathological lesions and increased risk for Alzheimer's dementia.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 10, p. 1163, doi. 10.1016/j.jalz.2014.10.013
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- Publication type:
- Article
Common genetic variation and schizophrenia polygenic risk influence neurocognitive performance in young adulthood.
- Published in:
- American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 2015, v. 168B, n. 5, p. 392, doi. 10.1002/ajmg.b.32323
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- Publication type:
- Article