Works by Rouru, Juha

Results: 15

Intracerebroventricular Glucocorticoid Infusion in Normal Rats: Induction of Parasympathetic-Mediated Obesity and Insulin Resistance.

Published in:

Obesity (19307381), 2001, v. 9, n. 7, p. 401, doi. 10.1038/oby.2001.52

By:

Cusin, Isabelle;
Rouru, Juha;
Rohner-Jeanrenaud, Françoise

Publication type:

Article

Application of the PET ligand [11C]ORM-13070 to examine receptor occupancy by the α2C-adrenoceptor antagonist ORM-12741: translational validation of target engagement in rat and human brain.

Published in:

EJNMMI Research, 2020, v. 10, n. 1, p. 1, doi. 10.1186/s13550-020-00741-y

By:

Shahid, Mohammed;
Rinne, Juha O.;
Scheinin, Mika;
Virta, Jere;
Marjamäki, Päivi;
Solin, Olof;
Arponen, Eveliina;
Sallinen, Jukka;
Kuokkanen, Katja;
Rouru, Juha

Publication type:

Article

Sensitivity of [C]ORM-13070 to increased extracellular noradrenaline in the CNS - a PET study in human subjects.

Published in:

Psychopharmacology, 2015, v. 232, n. 21/22, p. 4169, doi. 10.1007/s00213-015-3941-y

By:

Lehto, Jussi;
Johansson, Jarkko;
Vuorilehto, Lauri;
Luoto, Pauliina;
Arponen, Eveliina;
Scheinin, Harry;
Rouru, Juha;
Scheinin, Mika

Publication type:

Article

Hypothalamic Neurochemistry and Feeding Behavioral Responses to Clonidine, an Alpha-2-Agonist, and to Trifluoromethylphenylpiperazine, a Putative 5-Hydroxytryptamine-1B Agonist, in Genetically Obese Zucker Rats.

Published in:

Neuroendocrinology, 1990, v. 52, n. 5, p. 503, doi. 10.1159/000125635

By:

Koulu, Markku;
Huupponen, Risto;
Hänninen, Ham;
Pesonen, Ullamari;
Rouru, Juha;
Seppälä, Timo

Publication type:

Article

Acute inhibition of oestrogen biosynthesis does not affect serum leptin levels in young men.

Published in:

European Journal of Endocrinology, 2000, v. 142, n. 2, p. 164, doi. 10.1530/eje.0.1420164

By:

Luukkaa, Virve;
Rouru, Juha;
Ahokoski, Outi;
Scheinin, Harry;
Irjala, Kerttu;
Huupponen, Risto

Publication type:

Article

Correlation between circulating leptin and luteinizing hormone during the menstrual cycle in normal-weight women.

Published in:

European Journal of Endocrinology, 1998, v. 139, n. 2, p. 190, doi. 10.1530/eje.0.1390190

By:

Teirmaa, Tomi;
Luukkaa, Virve;
Rouru, Juha;
Koulu, Markku;
Huupponen, Risto

Publication type:

Article

The single dose pharmacokinetics and safety of deramciclane in healthy male volunteers.

Published in:

Biopharmaceutics & Drug Disposition, 1999, v. 20, n. 7, p. 327, doi. 10.1002/(SICI)1099-081X(199910)20:7<327::AID-BDD192>3.0.CO;2-8

By:

Kanerva, Harri;
Kilkku, Olavi;
Heinonen, Esa;
Helminen, Antti;
Rouru, Juha;
Tarpila, Simo;
Scheinin, Mika;
Huupponen, Risto;
Klebovich, Imre;
Drabant, Sandor;
Urtti, Arto

Publication type:

Article

Test-retest reliability of C-ORM-13070 in PET imaging of α-adrenoceptors in vivo in the human brain.

Published in:

European Journal of Nuclear Medicine & Molecular Imaging, 2015, v. 42, n. 1, p. 120, doi. 10.1007/s00259-014-2899-z

By:

Lehto, Jussi;
Virta, Jere;
Oikonen, Vesa;
Roivainen, Anne;
Luoto, Pauliina;
Arponen, Eveliina;
Helin, Semi;
Hietamäki, Johanna;
Holopainen, Aila;
Kailajärvi, Marita;
Peltonen, Juha;
Rouru, Juha;
Sallinen, Jukka;
Virtanen, Kirsi;
Volanen, Iina;
Scheinin, Mika;
Rinne, Juha

Publication type:

Article

C-ORM-13070, a novel PET ligand for brain α-adrenoceptors: radiometabolism, plasma pharmacokinetics, whole-body distribution and radiation dosimetry in healthy men.

Published in:

European Journal of Nuclear Medicine & Molecular Imaging, 2014, v. 41, n. 10, p. 1947, doi. 10.1007/s00259-014-2782-y

By:

Luoto, Pauliina;
Suilamo, Sami;
Oikonen, Vesa;
Arponen, Eveliina;
Helin, Semi;
Herttuainen, Jukka;
Hietamäki, Johanna;
Holopainen, Aila;
Kailajärvi, Marita;
Peltonen, Juha;
Rouru, Juha;
Sallinen, Jukka;
Scheinin, Mika;
Virta, Jere;
Virtanen, Kirsi;
Volanen, Iina;
Roivainen, Anne;
Rinne, Juha

Publication type:

Article

Validation of [11C]ORM-13070 as a PET tracer for alpha2c-adrenoceptors in the human brain.

Published in:

Synapse, 2015, v. 69, n. 3, p. 172, doi. 10.1002/syn.21798

By:

Lehto, Jussi;
Hirvonen, Mika M.;
Johansson, Jarkko;
Kemppainen, Jukka;
Luoto, Pauliina;
Naukkarinen, Tarja;
Oikonen, Vesa;
Arponen, Eveliina;
Rouru, Juha;
Sallinen, Jukka;
Scheinin, Harry;
Vuorilehto, Lauri;
Finnema, Sjoerd J.;
Halldin, Christer;
Rinne, Juha O.;
Scheinin, Mika

Publication type:

Article

Effect of the novel anxiolytic drug deramciclane on cytochrome P450 2D6 activity as measured by desipramine pharmacokinetics.

Published in:

European Journal of Clinical Pharmacology, 2004, v. 59, n. 12, p. 893, doi. 10.1007/s00228-003-0714-z

By:

Laine, Kari;
De Bruyn, Steven;
Björklund, Harry;
Rouru, Juha;
H&aul;nninen, Jutta;
Scheinin, Harry;
Anttila, Markku

Publication type:

Article

Effect of the novel anxiolytic drug deramciclane on the pharmacokinetics and pharmacodynamics of the CYP3A4 probe drug buspirone.

Published in:

European Journal of Clinical Pharmacology, 2003, v. 59, n. 10, p. 761, doi. 10.1007/s00228-003-0674-3

By:

Laine, Kari;
Ahokoski, Outi;
Huupponen, Risto;
Hänninen, Jutta;
Palovaara, Sanna;
Ruuskanen, Jori;
Björklund, Harry;
Anttila, Markku;
Rouru, Juha

Publication type:

Article

A double-blind, randomized, placebo-controlled crossover trial of the α2C-adrenoceptor antagonist ORM-12741 for prevention of cold-induced vasospasm in patients with systemic sclerosis.

Published in:

Rheumatology, 2014, v. 53, n. 5, p. 948, doi. 10.1093/rheumatology/ket421

By:

Herrick, Ariane L.;
Murray, Andrea K.;
Ruck, Angela;
Rouru, Juha;
Moore, Tonia L.;
Whiteside, John;
Hakulinen, Pasi;
Wigley, Fredrick;
Snapir, Amir

Publication type:

Article

Celiprolol augments the effect of physical exercise on insulin sensitivity and serum lipid levels in chronic heart failure.

Published in:

2000

By:

Pietilä, Mikko;
Malminiemi, Kimmo;
Huupponen, Risto;
Rouru, Juha;
Pulkki, Kari;
Pere, Erkki;
Voipio-Pulkki, Liisa-Maria;
Pietilä, M;
Malminiemi, K;
Huupponen, R;
Rouru, J;
Pulkki, K;
Pere, E;
Voipio-Pulkki, L M

Publication type:

journal article

Pharmacokinetics of Deramciclane, a Novel Anxiolytic Agent, after Intravenous and Oral Administration.

Published in:

Drugs in R&D, 2003, v. 4, n. 6, p. 339, doi. 10.2165/00126839-200304060-00002

By:

Huupponen, Risto;
Paija, Outi;
Salonen, Markku;
Björklund, Harry;
Rouru, Juha;
Anttila, Markku

Publication type:

Article

Works by Rouru, Juha

Intracerebroventricular Glucocorticoid Infusion in Normal Rats: Induction of Parasympathetic-Mediated Obesity and Insulin Resistance.

Application of the PET ligand [11C]ORM-13070 to examine receptor occupancy by the α2C-adrenoceptor antagonist ORM-12741: translational validation of target engagement in rat and human brain.

Sensitivity of [C]ORM-13070 to increased extracellular noradrenaline in the CNS - a PET study in human subjects.

Hypothalamic Neurochemistry and Feeding Behavioral Responses to Clonidine, an Alpha-2-Agonist, and to Trifluoromethylphenylpiperazine, a Putative 5-Hydroxytryptamine-1B Agonist, in Genetically Obese Zucker Rats.

Acute inhibition of oestrogen biosynthesis does not affect serum leptin levels in young men.

Correlation between circulating leptin and luteinizing hormone during the menstrual cycle in normal-weight women.

The single dose pharmacokinetics and safety of deramciclane in healthy male volunteers.

Test-retest reliability of C-ORM-13070 in PET imaging of α-adrenoceptors in vivo in the human brain.

C-ORM-13070, a novel PET ligand for brain α-adrenoceptors: radiometabolism, plasma pharmacokinetics, whole-body distribution and radiation dosimetry in healthy men.

Validation of [<sup>11</sup>C]ORM-13070 as a PET tracer for alpha<sub>2c</sub>-adrenoceptors in the human brain.

Effect of the novel anxiolytic drug deramciclane on cytochrome P<sub>450</sub> 2D6 activity as measured by desipramine pharmacokinetics.

Effect of the novel anxiolytic drug deramciclane on the pharmacokinetics and pharmacodynamics of the CYP3A4 probe drug buspirone.

A double-blind, randomized, placebo-controlled crossover trial of the α2C-adrenoceptor antagonist ORM-12741 for prevention of cold-induced vasospasm in patients with systemic sclerosis.

Celiprolol augments the effect of physical exercise on insulin sensitivity and serum lipid levels in chronic heart failure.

Pharmacokinetics of Deramciclane, a Novel Anxiolytic Agent, after Intravenous and Oral Administration.