Works by Rothstein, Rodney

Results: 62

Rad10 exhibits lesion-dependent genetic requirements for recruitment to DNA double-strand breaks in Saccharomyces cerevisiae.

Published in:

Nucleic Acids Research, 2009, v. 37, n. 19, p. 6429, doi. 10.1093/nar/gkp709

By:

Moore, Destaye M.;
Karlin, Justin;
González-Barrera, Sergio;
Mardiros, Armen;
Lisby, Michael;
Doughty, Ana;
Gilley, Jennifer;
Rothstein, Rodney;
Friedberg, Errol C.;
Fischhaber, Paula L.

Publication type:

Article

Multiple start codons and phosphorylation result in discrete Rad52 protein species.

Published in:

Nucleic Acids Research, 2006, v. 34, n. 9, p. 2587, doi. 10.1093/nar/gkl280

By:

de Mayolo, Adriana Antúnez;
Lisby, Michael;
Erdeniz, Naz;
Thybo, Tanja;
Mortensen, Uffe H.;
Rothstein, Rodney

Publication type:

Article

Cell Cycle-Regulated Centers of DNA Double-Strand Break Repair.

Published in:

Cell Cycle, 2003, v. 2, n. 5, p. 479, doi. 10.4161/cc.2.5.483

By:

Lisby, Michael;
De Mayolo, Adriana Antúnez;
Mortensen, Uffe H.;
Rothstein, Rodney

Publication type:

Article

Sec24p and Sec16p cooperate to regulate the GTP cycle of the COPII coat.

Published in:

EMBO Journal, 2012, v. 31, n. 4, p. 1014, doi. 10.1038/emboj.2011.444

By:

Kung, Leslie F;
Pagant, Silvere;
Futai, Eugene;
D'Arcangelo, Jennifer G;
Buchanan, Roy;
Dittmar, John C;
Reid, Robert J D;
Rothstein, Rodney;
Hamamoto, Susan;
Snapp, Erik L;
Schekman, Randy;
Miller, Elizabeth A

Publication type:

Article

Rad52 recruitment is DNA replication independent and regulated by Cdc28 and the Mec1 kinase.

Published in:

EMBO Journal, 2009, v. 28, n. 8, p. 1121, doi. 10.1038/emboj.2009.43

By:

Barlow, Jacqueline H.;
Rothstein, Rodney

Publication type:

Article

Sgs1 function in the repair of DNA replication intermediates is separable from its role in homologous recombinational repair.

Published in:

EMBO Journal, 2009, v. 28, n. 7, p. 915, doi. 10.1038/emboj.2009.28

By:

Bernstein, Kara A.;
Shor, Erika;
Sunjevaric, Ivana;
Fumasoni, Marco;
Burgess, Rebecca C.;
Foiani, Marco;
Branzei, Dana;
Rothstein, Rodney

Publication type:

Article

Quality control of DNA break metabolism: in the ‘end’, it's a good thing.

Published in:

EMBO Journal, 2008, v. 27, n. 4, p. 581, doi. 10.1038/emboj.2008.11

By:

Kanaar, Roland;
Wyman, Claire;
Rothstein, Rodney

Publication type:

Article

RMI1/NCE4, a suppressor of genome instability, encodes a member of the RecQ helicase/Topo III complex.

Published in:

EMBO Journal, 2005, v. 24, n. 11, p. 2024, doi. 10.1038/sj.emboj.7600684

By:

Chang, Michael;
Bellaoui, Mohammed;
Chaoying Zhang;
Desai, Ridhdhi;
Morozov, Pavel;
Delgado-Cruzata, Lissette;
Rothstein, Rodney;
Freyer, Greg A.;
Boone, Charles;
Brown, Grant W.

Publication type:

Article

Long telomeres are preferentially extended during recombination-mediated telomere maintenance.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 4, p. 451, doi. 10.1038/nsmb.2034

By:

Chang, Michael;
Dittmar, John C.;
Rothstein, Rodney

Publication type:

Article

Visualizing global effects of the DNA damage response.

Published in:

Nature Cell Biology, 2012, v. 14, n. 9, p. 900, doi. 10.1038/ncb2571

By:

Thorpe, Peter H.;
Rothstein, Rodney

Publication type:

Article

Increased chromosome mobility facilitates homology search during recombination.

Published in:

Nature Cell Biology, 2012, v. 14, n. 5, p. 510, doi. 10.1038/ncb2472

By:

Miné-Hattab, Judith;
Rothstein, Rodney

Publication type:

Article

The Smc5–Smc6 complex and SUMO modification of Rad52 regulates recombinational repair at the ribosomal gene locus.

Published in:

Nature Cell Biology, 2007, v. 9, n. 8, p. 923, doi. 10.1038/ncb1619

By:

Torres-Rosell, Jordi;
Sunjevaric, Ivana;
De Piccoli, Giacomo;
Sacher, Meik;
Eckert-Boulet, Nadine;
Reid, Robert;
Jentsch, Stefan;
Rothstein, Rodney;
Aragón, Luis;
Lisby, Michael

Publication type:

Article

Colocalization of multiple DNA double-strand breaks at a single Rad52 repair centre.

Published in:

Nature Cell Biology, 2003, v. 5, n. 6, p. 572, doi. 10.1038/ncb997

By:

Lisby, Michael;
Mortensen, Uffe H.;
Rothstein, Rodney

Publication type:

Article

Correction to: A role for the unfolded protein response stress sensor ERN1 in regulating the response to MEK inhibitors in KRAS mutant colon cancers.

Published in:

2021

By:

Šuštić, Tonći;
van Wageningen, Sake;
Bosdriesz, Evert;
Reid, Robert J. D.;
Dittmar, John;
Lieftink, Cor;
Beijersbergen, Roderick L.;
Wessels, Lodewyk F. A.;
Rothstein, Rodney;
Bernards, René

Publication type:

Correction Notice

YAC transgene-mediated olfactory receptor gene choice.

Published in:

Developmental Dynamics, 2000, v. 217, n. 2, p. 225, doi. 10.1002/(SICI)1097-0177(200002)217:2<225::AID-DVDY9>3.0.CO;2-3

By:

Ebrahimi, Farah A.W.;
Edmondson, James;
Rothstein, Rodney;
Chess, Andrew

Publication type:

Article

HDACs link the DNA damage response, processing of double-strand breaks and autophagy.

Published in:

Nature, 2011, v. 471, n. 7336, p. 74, doi. 10.1038/nature09803

By:

Robert, Thomas;
Vanoli, Fabio;
Chiolo, Irene;
Shubassi, Ghadeer;
Bernstein, Kara A.;
Rothstein, Rodney;
Botrugno, Oronza A.;
Parazzoli, Dario;
Oldani, Amanda;
Minucci, Saverio;
Foiani, Marco

Publication type:

Article

Recombination-Mediated Telomere Maintenance in Saccharomyces cerevisiae Is Not Dependent on the Shu Complex.

Published in:

PLoS ONE, 2016, v. 11, n. 3, p. 1, doi. 10.1371/journal.pone.0151314

By:

van Mourik, Paula M.;
de Jong, Jannie;
Agpalo, Danielle;
Claussin, Clémence;
Rothstein, Rodney;
Chang, Michael

Publication type:

Article

The shuffling of a mortal coil.

Published in:

Nature Genetics, 1999, v. 22, n. 1, p. 4, doi. 10.1038/8705

By:

Rothstein, Rodney;
Gangloff, Serge

Publication type:

Article

A Synthetic Dosage Lethal Genetic Interaction Between CKS1B and PLK1 Is Conserved in Yeast and Human Cancer Cells.

Published in:

Genetics, 2016, v. 204, n. 2, p. 807, doi. 10.1534/genetics.116.190231

By:

Reid, Robert J. D.;
Xing Du;
Sunjevaric, Ivana;
Rayannavar, Vinayak;
Dittmar, John;
Bryant, Eric;
Maurer, Matthew;
Rothstein, Rodney

Publication type:

Article

Mechanisms and Regulation of Mitotic Recombination in Saccharomyces cerevisiae.

Published in:

Genetics, 2014, v. 198, n. 3, p. 795, doi. 10.1534/genetics.114.166140

By:

Symington, Lorraine S.;
Rothstein, Rodney;
Lisby, Michael

Publication type:

Article

Resection Activity of the Sgs1 Helicase Alters the Affinity of DNA Ends for Homologous Recombination Proteins in Saccharomyces cerevisiae.

Published in:

Genetics, 2013, v. 195, n. 4, p. 1241, doi. 10.1534/genetics.113.157370

By:

Bernstein, Kara A.;
Mimitou, Eleni P.;
Mihalevic, Michael J.;
Huan Chen;
Sunjaveric, Ivana;
Symington, Lorraine S.;
Rothstein, Rodney

Publication type:

Article

Telomere Length Homeostasis Responds to Changes in Intracellular dNTP Pools.

Published in:

Genetics, 2013, v. 193, n. 4, p. 1095, doi. 10.1534/genetics.112.149120

By:

Gupta, Amitabha;
Sharma, Sushma;
Reichenbach, Patrick;
Marjavaara, Lisette;
Nilsson, Anna Karin;
Lingner, Joachim;
Chabes, Andrei;
Rothstein, Rodney;
Chang, Michael

Publication type:

Article

Telomerase Is Essential to Alleviate Pif1-Induced Replication Stress at Telomeres.

Published in:

Genetics, 2009, v. 183, n. 3, p. 779, doi. 10.1534/genetics.109.107631

By:

Chang, Michael;
Luke, Brian;
Kraft, Claudine;
Zhijian Li;
Peter, Matthias;
Lingner, Joachim;
Rothstein, Rodney

Publication type:

Article

Chromosome-Scale Genetic Mapping Using a Set of 16 Conditionally Stable Saccharomyces cerevisiae Chromosomes.

Published in:

Genetics, 2008, v. 180, n. 4, p. 1799, doi. 10.1534/genetics.108.087999

By:

Reid, Robert J. D.;
Sunjevaric, Ivana;
Voth, Warren P.;
Ciccone, Samantha;
Du, Wendy;
Olsen, Aileen E.;
Stillman, David J.;
Rothstein, Rodney

Publication type:

Article

The Absence of Top3 Reveals an Interaction Between the Sgs1 and Pif1 DNA Helicases in Saccharomyces cerevisiae.

Published in:

Genetics, 2006, v. 174, n. 2, p. 555, doi. 10.1534/genetics.104.036905

By:

Wagner, Marisa;
Price, Gavrielle;
Rothstein, Rodney

Publication type:

Article

A Genetic Screen for top3 Suppressors in Saccharomyces cerevisiae Identifies SHU1, SHU2, PSY3 and CSM2: Four Genes Involved in Error-Free DNA Repair.

Published in:

Genetics, 2005, v. 169, n. 3, p. 1275, doi. 10.1534/genetics.104.036764

By:

Shor, Erika;
Weinstein, Justin;
Rothstein, Rodney

Publication type:

Article

Mutations in Homologous Recombination Genes Rescue top3 Slow Growth in Saccharomyces cerevisiae.

Published in:

Genetics, 2002, v. 162, n. 2, p. 647, doi. 10.1093/genetics/162.2.647

By:

Shor, Erika;
Gangloff, Serge;
Wagner, Marisa;
Weinstein, Justin;
Price, Gavrielle;
Rothstein, Rodney

Publication type:

Article

A Molecular Genetic Dissection of the Evolutionarily Conserved N Terminus of Yeast Rad52.

Published in:

Genetics, 2002, v. 161, n. 2, p. 549, doi. 10.1093/genetics/161.2.549

By:

Mortensen, Uffe H.;
Erdeniz, Naz;
Qi Feng;
Rothstein, Rodney

Publication type:

Article

An allele of RFA1 suppresses RAD52-dependent double-strand break in Saccharomyces cerevisiae.

Published in:

Genetics, 1999, v. 151, n. 2, p. 447, doi. 10.1093/genetics/151.2.447

By:

Smith, Julianne;
Rothstein, Rodney

Publication type:

Article

Unrepaired heteroduplex DNA in Saccharomyces cerevisiae is decreased in RAD1 Rad52-independent...

Published in:

Genetics, 1994, v. 137, n. 2, p. 393, doi. 10.1093/genetics/137.2.393

By:

McDonald, John P.;
Rothstein, Rodney

Publication type:

Article

DNA lesions can frequently precede DNA:RNA hybrid accumulation.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-57588-x

By:

Mangione, Raphaël M.;
Pierce, Steven;
Zheng, Myriam;
Martin, Robert M.;
Goncalves, Coralie;
Kumar, Arun;
Scaglione, Sarah;
de Sousa Morgado, Cristiana;
Penzo, Arianna;
Lancrey, Astrid;
Reid, Robert J. D.;
Lautier, Ophélie;
Gaillard, Pierre-Henri;
Stirling, Peter C.;
de Almeida, Sérgio F.;
Rothstein, Rodney;
Palancade, Benoit

Publication type:

Article

A role for the unfolded protein response stress sensor ERN1 in regulating the response to MEK inhibitors in KRAS mutant colon cancers.

Published in:

Genome Medicine, 2018, v. 10, n. 1, p. N.PAG, doi. 10.1186/s13073-018-0600-z

By:

Šuštić, Tonći;
van Wageningen, Sake;
Bosdriesz, Evert;
Reid, Robert J. D.;
Dittmar, John;
Lieftink, Cor;
Beijersbergen, Roderick L.;
Wessels, Lodewyk F. A.;
Rothstein, Rodney;
Bernards, René

Publication type:

Article

Bringing Rad52 foci into focus.

Published in:

Journal of Cell Biology, 2011, v. 194, n. 5, p. 665, doi. 10.1083/jcb.201108095

By:

Thorpe, Peter H.;
Alvaro, David;
Lisby, Michael;
Rothstein, Rodney

Publication type:

Article

Localization of recombination proteins and Srs2 reveals anti-recombinase function in vivo.

Published in:

Journal of Cell Biology, 2009, v. 185, n. 6, p. 969, doi. 10.1083/jcb.200810055

By:

Burgess, Rebecca C.;
Lisby, Michael;
Altmannova, Veronika;
Krejci, Lumir;
Sung, Patrick;
Rothstein, Rodney

Publication type:

Article

Réparation de l'ADN: Comment trouver le bon partenaire ?

Published in:

Médecine Sciences, 2012, v. 28, n. 8-9, p. 714, doi. 10.1051/medsci/2012288014

By:

Miné-Hattab, Judith;
Rothstein, Rodney

Publication type:

Article

Most, but not all, yeast strains in the deletion library contain the [ PIN<sup>+</sup>] prion.

Published in:

Yeast, 2010, v. 27, n. 3, p. 159, doi. 10.1002/yea.1740

By:

Manogaran, Anita L.;
Fajardo, Viviana M.;
Reid, Robert J. D.;
Rothstein, Rodney;
Liebman, Susan W.

Publication type:

Article

Systematic hybrid LOH: a new method to reduce false positives and negatives during screening of yeast gene deletion libraries.

Published in:

Yeast, 2006, v. 23, n. 14/15, p. 1097, doi. 10.1002/yea.1423

By:

Alvaro, David;
Sunjevaric, Ivana;
Reid, Robert J. D.;
Lisby, Michael;
Stillman, David J.;
Rothstein, Rodney

Publication type:

Article

Efficient PCR-based gene disruption in Saccharomyces strains using intergenic primers.

Published in:

Yeast, 2002, v. 19, n. 4, p. 319, doi. 10.1002/yea.817

By:

Reid, Robert J.D.;
Sunjevaric, Ivana;
Kedacche, Mehdi;
Rothstein, Rodney

Publication type:

Article

The ribonucleotide reductase inhibitor Sml1 is a new target of the Mec1/Rad53 kinase cascade during growth and in response to DNA damage.

Published in:

EMBO Journal, 2001, v. 20, n. 13, p. 3544, doi. 10.1093/emboj/20.13.3544

By:

Zhao, Xiaolan;
Chabes, Andrei;
Domkin, Vladimir;
Thelander, Lars;
Rothstein, Rodney

Publication type:

Article

The essential role of yeast topoisomerase III in meiosis depends on recombination.

Published in:

EMBO Journal, 1999, v. 18, n. 6, p. 1701, doi. 10.1093/emboj/18.6.1701

By:

Gangloff, Serge;
de Massy, Bernard;
Arthur, Lane;
Rothstein, Rodney;
Fabre, Francis

Publication type:

Article

ScreenMill: A freely available software suite forgrowth measurement, analysis and visualization ofhigh-throughput screen data.

Published in:

BMC Bioinformatics, 2010, v. 11, p. 353, doi. 10.1186/1471-2105-11-353

By:

Dittmar, John C.;
Reid, Robert J. D.;
Rothstein, Rodney

Publication type:

Article

Rad5 dysregulation drives hyperactive recombination at replication forks resulting in cisplatin sensitivity and genome instability.

Published in:

Nucleic Acids Research, 2019, v. 47, n. 17, p. 9144, doi. 10.1093/nar/gkz631

By:

Bryant, Eric E;
Šunjevarić, Ivana;
Berchowitz, Luke;
Rothstein, Rodney;
Reid, Robert J D

Publication type:

Article

The ribonucleotide reductase inhibitor, Sml1, is sequentially phosphorylated, ubiquitylated and degraded in response to DNA damage.

Published in:

Nucleic Acids Research, 2010, v. 38, n. 19, p. 6490, doi. 10.1093/nar/gkq552

By:

Andreson, Bethany L.;
Gupta, Amitabha;
Georgieva, Bilyana P.;
Rothstein, Rodney

Publication type:

Article

ScreenTroll: a searchable database to compare genome-wide yeast screens.

Published in:

Database: The Journal of Biological Databases & Curation, 2012, v. 2012, p. 1, doi. 10.1093/database/bas022

By:

Thorpe, Peter H.;
Dittmar, John C.;
Rothstein, Rodney

Publication type:

Article

The PCNA Interaction Protein Box Sequence in Rad54 Is an Integral Part of Its ATPase Domain and Is Required for Efficient DNA Repair and Recombination.

Published in:

PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0082630

By:

Burgess, Rebecca C.;
Sebesta, Marek;
Sisakova, Alexandra;
Marini, Victoria P.;
Lisby, Michael;
Damborsky, Jiri;
Klein, Hannah;
Rothstein, Rodney;
Krejci, Lumir

Publication type:

Article

Histone H3K56 Acetylation, Rad52, and Non-DNA Repair Factors Control Double-Strand Break Repair Choice with the Sister Chromatid.

Published in:

PLoS Genetics, 2013, v. 9, n. 1, p. 1, doi. 10.1371/journal.pgen.1003237

By:

Muñoz-Galván, Sandra;
Jimeno, Sonia;
Rothstein, Rodney;
Aguilera, Andrés

Publication type:

Article

Rif2 Promotes a Telomere Fold-Back Structure through Rpd3L Recruitment in Budding Yeast.

Published in:

PLoS Genetics, 2012, v. 8, n. 9, p. 1, doi. 10.1371/journal.pgen.1002960

By:

Poschke, Heiko;
Dees, Martina;
Chang, Michael;
Amberkar, Sandeep;
Kaderali, Lars;
Rothstein, Rodney;
Luke, Brian

Publication type:

Article

The Ultimate (Mis)match: When DNA Meets RNA.

Published in:

Cells (2073-4409), 2021, v. 10, n. 6, p. 1433, doi. 10.3390/cells10061433

By:

Palancade, Benoit;
Rothstein, Rodney

Publication type:

Article

Aberrant DNA repair reveals a vulnerability in histone H3.3-mutant brain tumors.

Published in:

Nucleic Acids Research, 2024, v. 52, n. 5, p. 2372, doi. 10.1093/nar/gkad1257

By:

Giacomini, Giulia;
Piquet, Sandra;
Chevallier, Odile;
Dabin, Juliette;
Bai, Siau-Kun;
Kim, Byungjin;
Siddaway, Robert;
Raught, Brian;
Coyaud, Etienne;
Shan, Chun-Min;
Reid, Robert J D;
Toda, Takenori;
Rothstein, Rodney;
Barra, Viviana;
Wilhelm, Therese;
Hamadat, Sabah;
Bertin, Chloé;
Crane, Alexander;
Dubois, Frank;
Forne, Ignasi

Publication type:

Article

Timing is everything: cell cycle control of Rad52.

Published in:

Cell Division, 2010, v. 5, p. 7, doi. 10.1186/1747-1028-5-7

By:

Barlow, Jacqueline H.;
Rothstein, Rodney

Publication type:

Article