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Alzheimer‐like pathology in trisomy 21 cerebral organoids amenable to pharmacological inhibition reveals BACE2 as a gene‐dose‐sensitive AD‐suppressor in human brain: Development of new models and analysis methods: Multisystem platform models of ADRD
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043136
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- Article
Pathogenesis of Alzheimer's Disease.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 1, p. 107, doi. 10.3390/ijms24010107
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- Article
Characterization of a Mouse Model of Alzheimer's Disease Expressing Aβ4-42 and Human Mutant Tau.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 10, p. 5191, doi. 10.3390/ijms22105191
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- Article
Differential contribution of isoaspartate post-translational modifications to the fibrillization and toxic properties of amyloid ß and the Asn23 Iowa mutation.
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- Biochemical Journal, 2013, v. 456, n. 3, p. 347, doi. 10.1042/BJ20130652
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- Article
Correction to: Nrf2 activation through the PI3K/GSK-3 axisprotects neuronal cells from Aβ-mediatedoxidative and metabolic damage.
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- 2020
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- Correction Notice
Nrf2 activation through the PI3K/GSK-3 axis protects neuronal cells from Aβ-mediated oxidative and metabolic damage.
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- Alzheimer's Research & Therapy, 2020, v. 12, n. 1, p. 1, doi. 10.1186/s13195-019-0578-9
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- Article
Methazolamide protects neuronal and glial cells from amyloid toxicity in vitro and in vivo via mitochondria-mediated mechanisms.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P860, doi. 10.1016/j.jalz.2015.08.037
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- Article
Mitochondria and death receptors: key targets for amyloid toxicity in the cerebral vasculature.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2014, v. 10, p. P191, doi. 10.1016/j.jalz.2014.04.222
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- Article
Catabolism of Alzheimer's amyloid-β: Implications for brain clearance and plaque deposition
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- 2010
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- Abstract
Molecular analysis of apoptotic pathways induced by amyloid-β variants in cerebral vascular cells
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- 2010
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- Abstract
Fibrillogenesis and toxicity of Iowa-Aβ amyloid is primarily driven by the D23N mutation
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- 2010
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- Abstract
Involvement of the choroid plexus in the clearance of Aβ
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- 2010
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- Abstract
Pyroglutamate formation at the N-termini of ABri molecules in familial British dementia occurs at the sites of deposition and is not restricted to the central nervous system
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- 2010
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- Abstract
P4-078: Matrix metalloproteases and Aβ clearance
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- 2006
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- Abstract
P4-060: Oligomeric assemblies of the Aβ Dutch mutant induce the formation of nucleosomes in primary human cerebral endothelial cells
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- 2006
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- Abstract
P3-354: Post-translational modifications in Aβ and non-Aβ cerebral amyloidosis
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- 2006
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- Abstract
O2-03-06: BRI2 modulates amyloid precursor protein processing and inhibits aβ generation
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- 2006
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- Abstract
P4-078: Matrix metalloproteases and Aβ clearance
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- 2006
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- Publication type:
- Abstract
P4-060: Oligomeric assemblies of the Aβ Dutch mutant induce the formation of nucleosomes in primary human cerebral endothelial cells
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- 2006
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- Publication type:
- Abstract
P3-354: Post-translational modifications in Aβ and non-Aβ cerebral amyloidosis
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- 2006
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- Abstract
O2-03-06: BRI2 modulates amyloid precursor protein processing and inhibits aβ generation
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- 2006
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- Abstract
In vivo Differential Brain Clearance and Catabolism of Monomeric and Oligomeric Alzheimer's Aβ protein.
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- Frontiers in Aging Neuroscience, 2016, p. 1, doi. 10.3389/fnagi.2016.00223
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- Article
Insights into Caspase-Mediated Apoptotic Pathways Induced by Amyloid-β in Cerebral Microvascular Endothelial Cells.
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- Neurodegenerative Diseases, 2012, v. 10, n. 1-4, p. 324, doi. 10.1159/000332821
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- Article
Preamyloid Lesions and Cerebrovascular Deposits in the Mechanism of Dementia: Lessons from Non-β-Amyloid Cerebral Amyloidosis.
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- Neurodegenerative Diseases, 2008, v. 5, n. 3/4, p. 173, doi. 10.1159/000113694
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- Article
A Strategy for Designing a Peptide Probe for Detection of β-Amyloid Oligomers.
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- ChemBioChem, 2010, v. 11, n. 17, p. 2409, doi. 10.1002/cbic.201000435
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- Article
Localization of the ceavage sites on fibronectin following digestion by urokinase.
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- Journal of Cellular Biochemistry, 1992, v. 50, n. 4, p. 441, doi. 10.1002/jcb.240500412
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- Article
Amino‐terminally elongated Aβ peptides are generated by the secreted metalloprotease ADAMTS4 and deposit in a subset of Alzheimer's disease brains.
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- Neuropathology & Applied Neurobiology, 2024, v. 50, n. 3, p. 1, doi. 10.1111/nan.12991
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- Article
Initiation of translation from a downstream in-frame AUG codon on BRCA1 can generate the novel isoform protein ΔBRCA1(17aa).
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- Oncogene, 2000, v. 19, n. 23, p. 2767, doi. 10.1038/sj.onc.1203599
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- Article
The Extracellular Chaperone Clusterin in Aβ and Non‐Aβ Cerebral Amyloidoses.
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- FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R4076
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- Article
Enhanced Brain Retention of Aβ4‐x Proteoforms and its Contribution to Amyloid Deposits in Alzheimer's Disease.
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- FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R4023
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- Article
Genetics and molecular pathogenesis of sporadic and hereditary cerebral amyloid angiopathies.
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- 2009
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- Correction Notice
Genetics and molecular pathogenesis of sporadic and hereditary cerebral amyloid angiopathies.
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- Acta Neuropathologica, 2009, v. 118, n. 1, p. 115, doi. 10.1007/s00401-009-0501-8
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- Article
Oxidative Stress, Chronic Inflammation, and Amyloidoses.
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- Oxidative Medicine & Cellular Longevity, 2019, p. 1, doi. 10.1155/2019/6024975
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- Article
Apolipoprotein J (clusterin) and Alzheimer's disease.
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- Microscopy Research & Technique, 2000, v. 50, n. 4, p. 305, doi. 10.1002/1097-0029(20000815)50:4<305::AID-JEMT10>3.0.CO;2-L
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- Article
Sporadic and Familial Cerebral Amyloid Angiopathies.
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- Brain Pathology, 2002, v. 12, n. 3, p. 343, doi. 10.1111/j.1750-3639.2002.tb00449.x
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- Article
Cytokines and Disease.
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- Mediators of Inflammation, 2014, v. 2014, p. 1, doi. 10.1155/2014/209041
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- Article
Tumoral non-amyloidotic monoclonal immunoglobulin light chain deposits (aggregoma): presenting feature of B-cell dyscrasia in three cases with immunohistochemical and biochemical analyses.
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- British Journal of Haematology, 2002, v. 119, n. 1, p. 62, doi. 10.1046/j.1365-2141.2002.03781.x
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- Article
N-terminally truncated Aβ4-x proteoforms and their relevance for Alzheimer's pathophysiology.
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- Translational Neurodegeneration, 2022, v. 11, p. 1, doi. 10.1186/s40035-022-00303-3
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- Article
N-terminally truncated Aβ4-x proteoforms and their relevance for Alzheimer's pathophysiology.
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- Translational Neurodegeneration, 2022, v. 11, n. 1, p. 1, doi. 10.1186/s40035-022-00303-3
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- Article
Alzheimer's amyloid β heterogeneous species differentially affect brain endothelial cell viability, blood‐brain barrier integrity, and angiogenesis.
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- Aging Cell, 2020, v. 19, n. 11, p. 1, doi. 10.1111/acel.13258
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- Article
pH-dependent fibrillogenesis of a VκIII Bence Jones protein.
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- British Journal of Haematology, 1999, v. 107, n. 4, p. 835, doi. 10.1046/j.1365-2141.1999.01778.x
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- Article