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6-aza-5,8,10-trideaza analogues of tetrahydrofolic acid and tetrahydroaminopterin: Synthesis and biological studies.
- Published in:
- Journal of Heterocyclic Chemistry, 1989, v. 26, n. 2, p. 509, doi. 10.1002/jhet.5570260247
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- Publication type:
- Article
Methotrexate analogs. 7. Synthesis of two higher homologs and a positional isomer of methotrexate diethyl ester as potential antitumor agents.
- Published in:
- Journal of Heterocyclic Chemistry, 1976, v. 13, n. 4, p. 727, doi. 10.1002/jhet.5570130408
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- Publication type:
- Article
Pyrimido[4,5- c] isoquinolines. I. Synthesis of the parent compound and some 6-substituted derivatives.
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- Journal of Heterocyclic Chemistry, 1974, v. 11, n. 6, p. 1081, doi. 10.1002/jhet.5570110643
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- Publication type:
- Article
Side-chain altered methotrexate analogs designed for improved membrane transport.
- Published in:
- Journal of Heterocyclic Chemistry, 1973, v. 10, n. 3, p. 425, doi. 10.1002/jhet.5570100333
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- Publication type:
- Article
Quinazolines. IX. Direct amination via the chichibabin reaction.
- Published in:
- Journal of Heterocyclic Chemistry, 1972, v. 9, n. 6, p. 1449, doi. 10.1002/jhet.5570090651
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- Publication type:
- Article
Quinazolincs. X. Direct formation of aminoquinazolines from hydroxyquinazolines and phenyl phosphorodiamidate.
- Published in:
- Journal of Heterocyclic Chemistry, 1972, v. 9, n. 6, p. 1235, doi. 10.1002/jhet.5570090608
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- Publication type:
- Article
Quinazolines. XI. Synthesis of 2,4-diamino-5, 10-diliydrobenzo[g] quinazolines.
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- Journal of Heterocyclic Chemistry, 1972, v. 9, n. 6, p. 1239, doi. 10.1002/jhet.5570090609
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- Publication type:
- Article
Chemical and biological studies on dihydro- s-triazines. XVII. Modifications of the three-component synthesis favoring the formation of 2-guanidino-4-methylquinazoline byproducts.
- Published in:
- Journal of Heterocyclic Chemistry, 1972, v. 9, n. 3, p. 645, doi. 10.1002/jhet.5570090327
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- Publication type:
- Article
Chemical and biological studies on dihydro- s-triazines. XVI. Nmr evidence for the formation of 2-guanidino-4-methylquinazolines as anomalous byproducts in the three-component synthesis.
- Published in:
- Journal of Heterocyclic Chemistry, 1972, v. 9, n. 3, p. 637, doi. 10.1002/jhet.5570090326
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- Publication type:
- Article
Quinazolines. VIII. Synthesis of 1,3-diaminobenzo[ f]quinazolines.
- Published in:
- Journal of Heterocyclic Chemistry, 1972, v. 9, n. 2, p. 275, doi. 10.1002/jhet.5570090215
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- Publication type:
- Article
Quinazolines. VII. Synthesis of 1,3-Diamino-5,6-dihydrobenzo[ f]quinazolines.
- Published in:
- Journal of Heterocyclic Chemistry, 1972, v. 9, n. 2, p. 263, doi. 10.1002/jhet.5570090214
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- Publication type:
- Article
Synthesis of two new heterocyclic ring systems: Benzo[3,4] cyclohepta[1,2- d]-pyrimidines and benzo[3,4]cyclohepta[2,1- d] pyrimidines.
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- Journal of Heterocyclic Chemistry, 1971, v. 8, n. 5, p. 789, doi. 10.1002/jhet.5570080521
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- Publication type:
- Article
7-Benz[ c] acridinemethanols as tetracyclic analogs of the 2-phenyl-4-quinolinemethanol antimalarials.
- Published in:
- Journal of Heterocyclic Chemistry, 1971, v. 8, n. 5, p. 809, doi. 10.1002/jhet.5570080524
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- Publication type:
- Article
[1] Benzopyrano[3,4- d] pyrimidines and [1] benzothiopyrano[3,4- d] pyrimidines. Two new heterocyclic ring systems.
- Published in:
- Journal of Heterocyclic Chemistry, 1970, v. 7, n. 1, p. 197, doi. 10.1002/jhet.5570070131
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- Publication type:
- Article
Synthesis of 2,4-diamino-9 H-indeno[2,1- d]pyrimidines.
- Published in:
- Journal of Heterocyclic Chemistry, 1969, v. 6, n. 5, p. 613, doi. 10.1002/jhet.5570060503
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- Publication type:
- Article
Quinazolines. IV. a novel synthesis of 1,3-diamino-benzo[ f]quinazolines from N<sup>1</sup>, N<sup>5</sup>-bis(2-naphthyl)biguanides.
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- Journal of Heterocyclic Chemistry, 1966, v. 3, n. 3, p. 387, doi. 10.1002/jhet.5570030340
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- Publication type:
- Article
Continuous infusion high-dose leucovorin with 5-fluorouracil and cisplatin for untreated stage IV carcinoma of the head and neck.
- Published in:
- 1990
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- Publication type:
- journal article
Synthesis and antifolate activity of new pyrrolo[2,3- d]pyrimidine and thieno[2,3- d]pyrimidine inhibitors of dihydrofolate reductase.
- Published in:
- Journal of Heterocyclic Chemistry, 2004, v. 41, n. 5, p. 787, doi. 10.1002/jhet.5570410523
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- Publication type:
- Article
Synthesis of new 2,4-diamino-7 H-pyrrolo[2,3- d]pyrimidines via the Taylor ring transformation/ring annulation strategy.
- Published in:
- Journal of Heterocyclic Chemistry, 2001, v. 38, n. 5, p. 1197, doi. 10.1002/jhet.5570380526
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- Publication type:
- Article
Synthesis of 2,4-diaminopyrido[2,3- d]pyrimidines and 2,4-diamino-quinazolines with bulky dibenz[ b,f]azepine and dibenzo[ a,d]-cycloheptene substituents at the 6-position as inhibitors of dihydrofolate reductases from pneumocystis carinii, toxoplasma gondii, and mycobacterium avium
- Published in:
- Journal of Heterocyclic Chemistry, 2000, v. 37, n. 4, p. 921, doi. 10.1002/jhet.5570370440
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- Publication type:
- Article
One-step synthesis of novel 2,4-diaminopyrimidine antifolates from bridged alicyclic ketones and cyanoguanidine.
- Published in:
- Journal of Heterocyclic Chemistry, 1999, v. 36, n. 3, p. 723, doi. 10.1002/jhet.5570360324
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- Publication type:
- Article
Brominated trimetrexate analogues as inhibitors of pneumocystis carinii and toxoplasma gondii dihydrofolate reductase.
- Published in:
- Journal of Heterocyclic Chemistry, 1996, v. 33, n. 6, p. 1959, doi. 10.1002/jhet.5570330665
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- Publication type:
- Article
Inhibition of folylpolyglutamate synthetase by substrate analogues with an ornithine side chain.
- Published in:
- Journal of Heterocyclic Chemistry, 1996, v. 33, n. 4, p. 1355, doi. 10.1002/jhet.5570330457
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- Publication type:
- Article
Synthesis and antifolate activity of 2,4-diamino-5,6,7,8-tetrahydropyrido[4,3- d]pyrimidine analogues of trimetrexate and piritrexim.
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- Journal of Heterocyclic Chemistry, 1995, v. 32, n. 1, p. 335, doi. 10.1002/jhet.5570320155
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- Publication type:
- Article
5-Deaza-7-desmethylene analogues of 5,10-methylene-5,6,7,8-tetrahydrofolic acid and related compounds: Synthesis and in vitro biological activity.
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- Journal of Heterocyclic Chemistry, 1994, v. 31, n. 5, p. 1241, doi. 10.1002/jhet.5570310522
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- Publication type:
- Article
New insights into DHFR interactions: Analysis of Pneumocystis carinii and mouse DHFR complexes with NADPH and two highly potent 5-(ω-carboxy(alkyloxy) trimethoprim derivatives reveals conformational correlations with activity and novel parallel ring stacking interactions
- Published in:
- Proteins, 2006, v. 65, n. 4, p. 959, doi. 10.1002/prot.21131
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- Publication type:
- Article
Delivery of Lipophilic Drugs Using Lipoproteinsa.
- Published in:
- Annals of the New York Academy of Sciences, 1987, v. 507, n. 1, p. 252, doi. 10.1111/j.1749-6632.1987.tb45806.x
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- Publication type:
- Article
Antitumor Effects of L-Glutamic Acid Dihydroxyanilides Against Experimental Melanoma.
- Published in:
- Journal of Investigative Dermatology, 1980, v. 74, n. 2, p. 112, doi. 10.1111/1523-1747.ep12520030
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- Publication type:
- Article
DISCUSSION PAPER: SYNTHESIS AND BIOLOGICAL ACTIVITY OF TRICYCLIC ANTIFOLATE COMPOUNDS WITH FIXED GEOMETRY*.
- Published in:
- Annals of the New York Academy of Sciences, 1971, v. 186, n. 1, p. 258, doi. 10.1111/j.1749-6632.1971.tb46980.x
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- Publication type:
- Article
Synthesis of γ-[<sup>15</sup>N]-L-glutamyl derivatives of 5,10-dideazatetrahydrofolate.
- Published in:
- Journal of Labelled Compounds & Radiopharmaceuticals, 1999, v. 42, n. 11, p. 1103, doi. 10.1002/(SICI)1099-1344(199911)42:11<1103::AID-JLCR269>3.0.CO;2-E
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- Publication type:
- Article