Works by Rosenfeld, Nitzan

Results: 26

Noninvasive Identification and Monitoring of Cancer Mutations by Targeted Deep Sequencing of Plasma DNA.

Published in:

Science Translational Medicine, 2012, v. 4, n. 136, p. 1, doi. 10.1126/scitranslmed.3003726

By:

Forshew, Tim;
Murtaza, Muhammed;
Parkinson, Christine;
Gale, Davina;
Tsui, Dana W. Y.;
Kaper, Fiona;
Dawson, Sarah-Jane;
Piskorz, Anna M.;
Jimenez-Linan, Mercedes;
Bentley, David;
Hadfield, James;
May, Andrew P.;
Caldas, Carlos;
Brenton, James D.;
Rosenfeld, Nitzan

Publication type:

Article

Variability and memory of protein levels in human cells.

Published in:

Nature, 2006, v. 444, n. 7119, p. 643, doi. 10.1038/nature05316

By:

Sigal, Alex;
Milo, Ron;
Cohen, Ariel;
Geva-Zatorsky, Naama;
Klein, Yael;
Liron, Yuvalal;
Rosenfeld, Nitzan;
Danon, Tamar;
Perzov, Natalie;
Alon, Uri

Publication type:

Article

A standardized framework for robust fragmentomic feature extraction from cell-free DNA sequencing data.

Published in:

Genome Biology, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s13059-025-03607-5

By:

Wang, Haichao;
Mennea, Paulius D.;
Chan, Yu Kiu Elkie;
Cheng, Zhao;
Neofytou, Maria C.;
Surani, Arif Anwer;
Vijayaraghavan, Aadhitthya;
Ditter, Emma-Jane;
Bowers, Richard;
Eldridge, Matthew D.;
Shcherbo, Dmitry S.;
Smith, Christopher G.;
Markowetz, Florian;
Cooper, Wendy N.;
Kaplan, Tommy;
Rosenfeld, Nitzan;
Zhao, Hui

Publication type:

Article

Kinome capture sequencing of high-grade serous ovarian carcinoma reveals novel mutations in the JAK3 gene.

Published in:

PLoS ONE, 2020, v. 15, n. 7, p. 1, doi. 10.1371/journal.pone.0235766

By:

Mittempergher, Lorenza;
Piskorz, Anna M.;
Bosma, Astrid J.;
Michaut, Magali;
Wisman, G. Bea A.;
Kluin, Roelof J. C.;
Nieuwland, Marja;
Brugman, Wim;
van der Ven, Kevin J. W.;
Marass, Francesco;
Morris, James;
Rosenfeld, Nitzan;
Jimenez-Linan, Mercedes;
de Jong, Steven;
van der Zee, Ate G. J.;
Brenton, James D.;
Bernards, René

Publication type:

Article

Circulating cell free DNA during definitive chemo-radiotherapy in non-small cell lung cancer patients – initial observations.

Published in:

PLoS ONE, 2020, v. 15, n. 4, p. 1, doi. 10.1371/journal.pone.0231884

By:

Nygård, Lotte;
Ahlborn, Lise B.;
Persson, Gitte F.;
Chandrananda, Dineika;
Langer, Jonathan W.;
Fischer, Barbara M.;
Langer, Seppo W.;
Gabrielaite, Miglė;
Kjær, Andreas;
Rosenfeld, Nitzan;
Mouliere, Florent;
Østrup, Olga;
Vogelius, Ivan R.;
Bentzen, Søren M.

Publication type:

Article

MiR-92b and miR-9/9* Are Specifically Expressed in Brain Primary Tumors and Can Be Used to Differentiate Primary from Metastatic Brain Tumors.

Published in:

Brain Pathology, 2009, v. 19, n. 3, p. 375, doi. 10.1111/j.1750-3639.2008.00184.x

By:

Nass, Dvora;
Rosenwald, Shai;
Meiri, Eti;
Gilad, Shlomit;
Tabibian-Keissar, Hilla;
Schlosberg, Anat;
Kuker, Hagit;
Sion-Vardy, Netta;
Tobar, Ana;
Kharenko, Oleg;
Sitbon, Einat;
Yanai, Gila Lithwick;
Elyakim, Eran;
Cholakh, Hila;
Gibori, Hadas;
Spector, Yael;
Bentwich, Zvi;
Barshack, Iris;
Rosenfeld, Nitzan

Publication type:

Article

Dynamics of the p53-Mdm2 feedback loop in individual cells.

Published in:

Nature Genetics, 2004, v. 36, n. 2, p. 147, doi. 10.1038/ng1293

By:

Lahav, Galit;
Rosenfeld, Nitzan;
Sigal, Alex;
Geva-Zatorsky, Naama;
Levine, Arnold J.;
Elowitz, Michael B.;
Alon, Uri

Publication type:

Article

Exploratory Analysis of TP53 Mutations in Circulating Tumour DNA as Biomarkers of Treatment Response for Patients with Relapsed High-Grade Serous Ovarian Carcinoma: A Retrospective Study.

Published in:

2016

By:

Parkinson, Christine A.;
Gale, Davina;
Piskorz, Anna M.;
Biggs, Heather;
Hodgkin, Charlotte;
Addley, Helen;
Freeman, Sue;
Moyle, Penelope;
Sala, Evis;
Sayal, Karen;
Hosking, Karen;
Gounaris, Ioannis;
Jimenez-Linan, Mercedes;
Earl, Helena M.;
Qian, Wendi;
Rosenfeld, Nitzan;
Brenton, James D.

Publication type:

journal article

Spatial and Temporal Heterogeneity in High-Grade Serous Ovarian Cancer: A Phylogenetic Analysis.

Published in:

PLoS Medicine, 2015, v. 12, n. 2, p. 1, doi. 10.1371/journal.pmed.1001789

By:

Schwarz, Roland F.;
Ng, Charlotte K. Y.;
Cooke, Susanna L.;
Newman, Scott;
Temple, Jillian;
Piskorz, Anna M.;
Gale, Davina;
Sayal, Karen;
Murtaza, Muhammed;
Baldwin, Peter J.;
Rosenfeld, Nitzan;
Earl, Helena M.;
Sala, Evis;
Jimenez-Linan, Mercedes;
Parkinson, Christine A.;
Markowetz, Florian;
Brenton, James D.

Publication type:

Article

Analytical validation of a next generation sequencing liquid biopsy assay for high sensitivity broad molecular profiling.

Published in:

PLoS ONE, 2018, v. 13, n. 3, p. 1, doi. 10.1371/journal.pone.0193802

By:

Plagnol, Vincent;
Woodhouse, Samuel;
Howarth, Karen;
Lensing, Stefanie;
Smith, Matt;
Epstein, Michael;
Madi, Mikidache;
Smalley, Sarah;
Leroy, Catherine;
Hinton, Jonathan;
de Kievit, Frank;
Musgrave-Brown, Esther;
Herd, Colin;
Baker-Neblett, Katherine;
Brennan, Will;
Dimitrov, Peter;
Campbell, Nathan;
Morris, Clive;
Rosenfeld, Nitzan;
Clark, James

Publication type:

Article

Correlating Radiomic Features of Heterogeneity on CT with Circulating Tumor DNA in Metastatic Melanoma.

Published in:

Cancers, 2020, v. 12, n. 12, p. 3493, doi. 10.3390/cancers12123493

By:

Gill, Andrew B.;
Rundo, Leonardo;
Wan, Jonathan C. M.;
Lau, Doreen;
Zawaideh, Jeries P.;
Woitek, Ramona;
Zaccagna, Fulvio;
Beer, Lucian;
Gale, Davina;
Sala, Evis;
Couturier, Dominique-Laurent;
Corrie, Pippa G.;
Rosenfeld, Nitzan;
Gallagher, Ferdia A.

Publication type:

Article

Comparison of tumor‐informed and tumor‐naïve sequencing assays for ctDNA detection in breast cancer.

Published in:

EMBO Molecular Medicine, 2023, v. 15, n. 6, p. 1, doi. 10.15252/emmm.202216505

By:

Santonja, Angela;
Cooper, Wendy N;
Eldridge, Matthew D;
Edwards, Paul A W;
Morris, James A;
Edwards, Abigail R;
Zhao, Hui;
Heider, Katrin;
Couturier, Dominique‐Laurent;
Vijayaraghavan, Aadhitthya;
Mennea, Paulius;
Ditter, Emma‐Jane;
Smith, Christopher G;
Boursnell, Chris;
Manzano García, Raquel;
Rueda, Oscar M;
Beddowes, Emma;
Biggs, Heather;
Sammut, Stephen‐John;
Rosenfeld, Nitzan

Publication type:

Article

Longitudinal monitoring of disease burden and response using ctDNA from dried blood spots in xenograft models.

Published in:

EMBO Molecular Medicine, 2022, v. 14, n. 8, p. 1, doi. 10.15252/emmm.202215729

By:

Sauer, Carolin M;
Heider, Katrin;
Belic, Jelena;
Boyle, Samantha E;
Hall, James A;
Couturier, Dominique‐Laurent;
An, Angela;
Vijayaraghavan, Aadhitthya;
Reinius, Marika AV;
Hosking, Karen;
Vias, Maria;
Rosenfeld, Nitzan;
Brenton, James D

Publication type:

Article

Fragmentation patterns and personalized sequencing of cell‐free DNA in urine and plasma of glioma patients.

Published in:

EMBO Molecular Medicine, 2021, v. 13, n. 8, p. 1, doi. 10.15252/emmm.202012881

By:

Mouliere, Florent;
Smith, Christopher G;
Heider, Katrin;
Su, Jing;
van der Pol, Ymke;
Thompson, Mareike;
Morris, James;
Wan, Jonathan C M;
Chandrananda, Dineika;
Hadfield, James;
Grzelak, Marta;
Hudecova, Irena;
Couturier, Dominique‐Laurent;
Cooper, Wendy;
Zhao, Hui;
Gale, Davina;
Eldridge, Matthew;
Watts, Colin;
Brindle, Kevin;
Rosenfeld, Nitzan

Publication type:

Article

Detection of cell‐free DNA fragmentation and copy number alterations in cerebrospinal fluid from glioma patients.

Published in:

EMBO Molecular Medicine, 2018, v. 10, n. 12, p. N.PAG, doi. 10.15252/emmm.201809323

By:

Mouliere, Florent;
Mair, Richard;
Chandrananda, Dineika;
Marass, Francesco;
Smith, Christopher G;
Su, Jing;
Morris, James;
Watts, Colin;
Brindle, Kevin M;
Rosenfeld, Nitzan

Publication type:

Article

Dynamics of multiple resistance mechanisms in plasma DNA during EGFR‐targeted therapies in non‐small cell lung cancer.

Published in:

EMBO Molecular Medicine, 2018, v. 10, n. 6, p. 1, doi. 10.15252/emmm.201707945

By:

Tsui, Dana Wai Yi;
Murtaza, Muhammed;
Wong, Alvin Seng Cheong;
Rueda, Oscar M.;
Smith, Christopher G.;
Chandrananda, Dineika;
Soo, Ross A.;
Lim, Hong Liang;
Goh, Boon Cher;
Caldas, Carlos;
Forshew, Tim;
Gale, Davina;
Liu, Wei;
Morris, James;
Marass, Francesco;
Eisen, Tim;
Chin, Tan Min;
Rosenfeld, Nitzan

Publication type:

Article

Recurrence prediction using circulating tumor DNA in patients with early-stage non-small cell lung cancer after treatment with curative intent: A retrospective validation study.

Published in:

PLoS Medicine, 2025, v. 22, n. 4, p. 1, doi. 10.1371/journal.pmed.1004574

By:

Schuurbiers, Milou M. F.;
Smith, Christopher G.;
Hartemink, Koen J.;
Rintoul, Robert C.;
Gale, Davina;
Monkhorst, Kim;
Mandos, Bas L. R.;
Paterson, Anna L.;
van den Broek, Dan;
Rosenfeld, Nitzan;
van den Heuvel, Michel M.

Publication type:

Article

Detection of ctDNA from Dried Blood Spots after DNA Size Selection.

Published in:

Clinical Chemistry, 2020, v. 66, n. 5, p. 697, doi. 10.1093/clinchem/hvaa050

By:

Heider, Katrin;
Wan, Jonathan C. M.;
Hall, James;
Belic, Jelena;
Boyle, Samantha;
Hudecova, Irena;
Gale, Davina;
Cooper, Wendy N.;
Corrie, Pippa G.;
Brenton, James D.;
Smith, Christopher G.;
Rosenfeld, Nitzan

Publication type:

Article

Accurate prediction of gene feedback circuit behavior from component properties.

Published in:

Molecular Systems Biology, 2007, v. 3, n. 1, p. 1, doi. 10.1038/msb4100185

By:

Rosenfeld, Nitzan;
Young, Jonathan W;
Alon, Uri;
Swain, Peter S;
Elowitz, Michael B

Publication type:

Article

Oscillations and variability in the p53 system.

Published in:

Molecular Systems Biology, 2006, v. 2, n. 1, p. E1, doi. 10.1038/msb4100068

By:

Geva‐Zatorsky, Naama;
Rosenfeld, Nitzan;
Itzkovitz, Shalev;
Milo, Ron;
Sigal, Alex;
Dekel, Erez;
Yarnitzky, Talia;
Liron, Yuvalal;
Polak, Paz;
Lahav, Galit;
Alon, Uri

Publication type:

Article

Clinical and pathological impact of VHL, PBRM1, BAP1, SETD2, KDM6A, and JARID1c in clear cell renal cell carcinoma.

Published in:

Genes, Chromosomes & Cancer, 2014, v. 53, n. 1, p. 38, doi. 10.1002/gcc.22116

By:

Gossage, Lucy;
Murtaza, Muhammed;
Slatter, Andrew F.;
Lichtenstein, Conrad P.;
Warren, Anne;
Haynes, Beverley;
Marass, Francesco;
Roberts, Ian;
Shanahan, Susan J.;
Claas, Andreas;
Dunham, Andrew;
May, Andrew P.;
Rosenfeld, Nitzan;
Forshew, Tim;
Eisen, Tim

Publication type:

Article

Comparison of two targeted ultra-deep sequencing technologies for analysis of plasma circulating tumour DNA in endocrine-therapy-resistant breast cancer patients.

Published in:

Breast Cancer Research & Treatment, 2021, v. 188, n. 2, p. 465, doi. 10.1007/s10549-021-06220-9

By:

Nteliopoulos, Georgios;
Page, Karen;
Hills, Allison;
Howarth, Karen;
Emmett, Warren;
Green, Emma;
Martinson, Luke J.;
Fernadez-Garcia, Daniel;
Hastings, Robert;
Guttery, David S.;
Kenny, Laura;
Stebbing, Justin;
Cleator, Susan;
Rehman, Farah;
Gleason, Kelly L. T.;
Sanela, Andrijac;
Ion, Charlotte;
Rushton, Amelia J.;
Rosenfeld, Nitzan;
Coombes, R. Charles

Publication type:

Article

Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA.

Published in:

Nature, 2013, v. 497, n. 7447, p. 108, doi. 10.1038/nature12065

By:

Murtaza, Muhammed;
Dawson, Sarah-Jane;
Tsui, Dana W. Y.;
Gale, Davina;
Forshew, Tim;
Piskorz, Anna M.;
Parkinson, Christine;
Chin, Suet-Feung;
Kingsbury, Zoya;
Wong, Alvin S. C.;
Marass, Francesco;
Humphray, Sean;
Hadfield, James;
Bentley, David;
Chin, Tan Min;
Brenton, James D.;
Caldas, Carlos;
Rosenfeld, Nitzan

Publication type:

Article

Refined characterization of circulating tumor DNA through biological feature integration.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-05606-z

By:

Markus, Havell;
Chandrananda, Dineika;
Moore, Elizabeth;
Mouliere, Florent;
Morris, James;
Brenton, James D.;
Smith, Christopher G.;
Rosenfeld, Nitzan

Publication type:

Article

CVE: an R package for interactive variant prioritisation in precision oncology.

Published in:

BMC Medical Genomics, 2017, v. 10, p. 1, doi. 10.1186/s12920-017-0261-6

By:

Mock, Andreas;
Murphy, Suzanne;
Morris, James;
Marass, Francesco;
Rosenfeld, Nitzan;
Massie, Charlie

Publication type:

Article

MicroRNAs accurately identify cancer tissue origin.

Published in:

Nature Biotechnology, 2008, v. 26, n. 4, p. 462, doi. 10.1038/nbt1392

By:

Rosenfeld, Nitzan;
Aharonov, Ranit;
Meiri, Eti;
Rosenwald, Shai;
Spector, Yael;
Zepeniuk, Merav;
Benjamin, Hila;
Shabes, Norberto;
Tabak, Sarit;
Levy, Asaf;
Lebanony, Danit;
Goren, Yaron;
Silberschein, Erez;
Targan, Nurit;
Ben-Ari, Alex;
Gilad, Shlomit;
Sion-Vardy, Netta;
Tobar, Ana;
Feinmesser, Meora;
Kharenko, Oleg

Publication type:

Article