Works by Rosen, Lee S.

Results: 28

Relationship between exposure to sunitinib and efficacy and tolerability endpoints in patients with cancer: results of a pharmacokinetic/pharmacodynamic meta-analysis.

Published in:

Cancer Chemotherapy & Pharmacology, 2010, v. 66, n. 2, p. 357, doi. 10.1007/s00280-009-1170-y

By:

Houk, Brett E.;
Bello, Carlo L.;
Poland, Bill;
Rosen, Lee S.;
Demetri, George D.;
Motzer, Robert J.

Publication type:

Article

Sunitinib Induces Hypothyroidism in Advanced Cancer Patients and May Inhibit Thyroid Peroxidase Activity.

Published in:

Thyroid, 2007, v. 17, n. 4, p. 351, doi. 10.1089/thy.2006.0308

By:

Elaine Wong;
Lee S. Rosen;
Marilyn Mulay;
Andy VanVugt;
Melissa Dinolfo;
Chisato Tomoda;
Masahiro Sugawara;
Jerome M. Hershman

Publication type:

Article

Phase 1 trials of PEGylated recombinant human hyaluronidase PH20 in patients with advanced solid tumours.

Published in:

British Journal of Cancer, 2018, v. 118, n. 2, p. 153, doi. 10.1038/bjc.2017.327

By:

Infante, Jeffrey R;
Korn, Ronald L;
Rosen, Lee S;
LoRusso, Patricia;
Dychter, Samuel S;
Zhu, Joy;
Maneval, Daniel C;
Jiang, Ping;
Shepard, H Michael;
Frost, Gregory;
Von Hoff, Daniel D;
Borad, Mitesh J;
Ramanathan, Ramesh K

Publication type:

Article

Phase 1 trials of PEGylated recombinant human hyaluronidase PH20 in patients with advanced solid tumours.

Published in:

2018

By:

Infante, Jeffrey R;
Korn, Ronald L;
Rosen, Lee S;
LoRusso, Patricia;
Dychter, Samuel S;
Zhu, Joy;
Maneval, Daniel C;
Jiang, Ping;
Shepard, H Michael;
Frost, Gregory;
Von Hoff, Daniel D;
Borad, Mitesh J;
Ramanathan, Ramesh K

Publication type:

corrected article

Phase 1 trials of PEGylated recombinant human hyaluronidase PH20 in patients with advanced solid tumours.

Published in:

2017

By:

Infante, Jeffrey R;
Korn, Ronald L;
Rosen, Lee S;
LoRusso, Patricia;
Dychter, Samuel S;
Zhu, Joy;
Maneval, Daniel C;
Jiang, Ping;
Shepard, H Michael;
Frost, Gregory;
Von Hoff, Daniel D;
Borad, Mitesh J;
Ramanathan, Ramesh K

Publication type:

journal article

Targeting Signal Transduction Pathways in Metastatic Breast Cancer: A Comprehensive Review.

Published in:

Oncologist, 2010, v. 15, n. 3, p. 216, doi. 10.1634/theoncologist.2009-0145

By:

Rosen, Lee S.;
Ashurst, Helen Louise;
Chap, Linnea

Publication type:

Article

Phase II trial of irinotecan in combination with amifostine in patients with advanced colorectal carcinoma.

Published in:

2002

By:

Delioukina, Maria L.;
Prager, Diane;
Parson, Mandy;
Hecht, J. Randolph;
Rosen, Peter;
Rosen, Lee S.

Publication type:

journal article

Zoledronic acid reduces skeletal-related events in patients with osteolytic metastases.

Published in:

2001

By:

Berenson, James R.;
Rosen, Lee S.;
Howell, Anthony;
Porter, Lester;
Coleman, Robert E.;
Morley, Walter;
Dreicer, Robert;
Kuross, Steven A.;
Lipton, Allan;
Seaman, John J.;
Berenson, J R;
Rosen, L S;
Howell, A;
Porter, L;
Coleman, R E;
Morley, W;
Dreicer, R;
Kuross, S A;
Lipton, A;
Seaman, J J

Publication type:

journal article

Clinical outcomes of patients with advanced gastrointestinal stromal tumors: Safety and efficacy in a worldwide treatment-use trial of sunitinib.

Published in:

Cancer (0008543X), 2015, v. 121, n. 9, p. 1405, doi. 10.1002/cncr.29220

By:

Reichardt, Peter;
Kang, Yoon‐Koo;
Rutkowski, Piotr;
Schuette, Jochen;
Rosen, Lee S.;
Seddon, Beatrice;
Yalcin, Suayib;
Gelderblom, Hans;
Williams, Charles C.;
Fumagalli, Elena;
Biasco, Guido;
Hurwitz, Herbert I.;
Kaiser, Pamela E.;
Fly, Kolette;
Matczak, Ewa;
Chen, Liang;
Lechuga, Maria José;
Demetri, George D.

Publication type:

Article

Phase 1 dose-escalation trial evaluating the combination of the selective MET (mesenchymal-epithelial transition factor) inhibitor tivantinib (ARQ 197) plus erlotinib.

Published in:

Cancer (0008543X), 2012, v. 118, n. 23, p. 5903, doi. 10.1002/cncr.27575

By:

Goldman, Jonathan W.;
Laux, Isett;
Chai, Feng;
Savage, Ronald E.;
Ferrari, Dora;
Garmey, Edward G.;
Just, Richard G.;
Rosen, Lee S.

Publication type:

Article

Comparison of the pharmacokinetics and pharmacodynamics of S-1 between Caucasian and East Asian patients.

Published in:

Cancer Science, 2011, v. 102, n. 2, p. 478, doi. 10.1111/j.1349-7006.2010.01793.x

By:

Chuah, Benjamin;
Goh, Boon-Cher;
Lee, Soo-Chin;
Soong, Richie;
Lau, Fayce;
Mulay, Marilyn;
Dinolfo, Melissa;
Lim, Siew-Eng;
Soo, Ross;
Furuie, Taro;
Saito, Kaku;
Zergebel, Christopher;
Rosen, Lee S.

Publication type:

Article

Phase I study of the anti-α5β1 monoclonal antibody MINT1526A with or without bevacizumab in patients with advanced solid tumors.

Published in:

2018

By:

Weekes, Colin D.;
Rosen, Lee S.;
Capasso, Anna;
Wong, Kit Man;
Ye, Weilan;
Anderson, Maria;
McCall, Bruce;
Fredrickson, Jill;
Wakshull, Eric;
Eppler, Steve;
Shon-Nguyen, Quyen;
Desai, Rupal;
Huseni, Mahrukh;
Hegde, Priti S.;
Pourmohamad, Tony;
Rhee, Ina;
Bessudo, Alberto

Publication type:

journal article

Erratum to: Phase 1 study of oral TAS-102 in patients with refractory metastatic colorectal cancer.

Published in:

2016

By:

Bendell, Johanna;
Rosen, Lee;
Mayer, Robert;
Goldman, Jonathan;
Infante, Jeffrey;
Benedetti, Fabio;
Lin, Donghu;
Mizuguchi, Hirokazu;
Zergebel, Christopher;
Patel, Manish;
Bendell, Johanna C;
Rosen, Lee S;
Mayer, Robert J;
Goldman, Jonathan W;
Infante, Jeffrey R;
Patel, Manish R

Publication type:

corrected article

Phase 1 study of oral TAS-102 in patients with refractory metastatic colorectal cancer.

Published in:

2015

By:

Bendell, Johanna;
Rosen, Lee;
Mayer, Robert;
Goldman, Jonathan;
Infante, Jeffrey;
Benedetti, Fabio;
Lin, Donghu;
Mizuguchi, Hirokazu;
Zergebel, Christopher;
Patel, Manish;
Bendell, Johanna C;
Rosen, Lee S;
Mayer, Robert J;
Goldman, Jonathan W;
Infante, Jeffrey R;
Patel, Manish R

Publication type:

journal article

Safety, efficacy, and pharmacokinetics of navitoclax (ABT-263) in combination with erlotinib in patients with advanced solid tumors.

Published in:

2015

By:

Tolcher, Anthony;
LoRusso, Patricia;
Arzt, Jennifer;
Busman, Todd;
Lian, Guinan;
Rudersdorf, Niki;
Vanderwal, Carol;
Kirschbrown, Whitney;
Holen, Kyle;
Rosen, Lee;
Tolcher, Anthony W;
Busman, Todd A;
Rudersdorf, Niki S;
Vanderwal, Carol Ann;
Holen, Kyle D;
Rosen, Lee S

Publication type:

journal article

Safety, efficacy, and pharmacokinetics of navitoclax (ABT-263) in combination with irinotecan: results of an open-label, phase 1 study.

Published in:

2015

By:

Tolcher, Anthony;
LoRusso, Patricia;
Arzt, Jennifer;
Busman, Todd;
Lian, Guinan;
Rudersdorf, Niki;
Vanderwal, Carol;
Waring, Jeffrey;
Yang, Jianning;
Holen, Kyle;
Rosen, Lee;
Tolcher, Anthony W;
Busman, Todd A;
Rudersdorf, Niki S;
Vanderwal, Carol Ann;
Waring, Jeffrey F;
Holen, Kyle D;
Rosen, Lee S

Publication type:

journal article

The effect of different dosing regimens of motesanib on the gallbladder: a randomized phase 1b study in patients with advanced solid tumors.

Published in:

BMC Cancer, 2013, v. 13, n. 1, p. 1, doi. 10.1186/1471-2407-13-242

By:

Rosen, Lee S.;
Lipton, Lara;
Price, Timothy J.;
Belman, Neil D.;
Boccia, Ralph V.;
Hurwitz, Herbert I.;
Stephenson Jr, Joe J.;
Wirth, Lori J.;
McCoy, Sheryl;
Yong-jiang Hei;
Cheng-Pang Hsu;
Tebbutt, Niall C.

Publication type:

Article

A first in human, safety, pharmacokinetics, and clinical activity phase I study of once weekly administration of the Hsp90 inhibitor ganetespib (STA-9090) in patients with solid malignancies.

Published in:

BMC Cancer, 2013, v. 13, n. 1, p. 1, doi. 10.1186/1471-2407-13-152

By:

Goldman, Jonathan W.;
Raju, Robert N.;
Gordon, Gregory A.;
El-Hariry, Iman;
Teofilivici, Florentina;
Vukovic, Vojo M.;
Bradley, Robert;
Karol, Michael D.;
Yu Chen;
Wei Guo;
Inoue, Takayo;
Rosen, Lee S

Publication type:

Article

A first in human, safety, pharmacokinetics, and clinical activity phase I study of once weekly administration of the Hsp90 inhibitor ganetespib (STA-9090) in patients with solid malignancies.

Published in:

2013

By:

Goldman, Jonathan W;
Raju, Robert N;
Gordon, Gregory A;
El-Hariry, Iman;
Teofilivici, Florentina;
Vukovic, Vojo M;
Bradley, Robert;
Karol, Michael D;
Chen, Yu;
Guo, Wei;
Inoue, Takayo;
Rosen, Lee S

Publication type:

journal article

The effect of different dosing regimens of motesanib on the gallbladder: a randomized phase 1b study in patients with advanced solid tumors.

Published in:

2013

By:

Rosen, Lee S;
Lipton, Lara;
Price, Timothy J;
Belman, Neil D;
Boccia, Ralph V;
Hurwitz, Herbert I;
Stephenson Jr, Joe J;
Wirth, Lori J;
McCoy, Sheryl;
Hei, Yong-Jiang;
Hsu, Cheng-Pang;
Tebbutt, Niall C;
Stephenson, Joe J Jr

Publication type:

journal article

Clinical translation of ferumoxytol-based vessel size imaging (VSI): Feasibility in a phase I oncology clinical trial population.

Published in:

Magnetic Resonance in Medicine, 2017, v. 77, n. 2, p. 814, doi. 10.1002/mrm.26167

By:

Fredrickson, Jill;
Serkova, Natalie J.;
Wyatt, Shelby K.;
Carano, Richard A.D.;
Pirzkall, Andrea;
Rhee, Ina;
Rosen, Lee S.;
Bessudo, Alberto;
Weekes, Colin;
de Crespigny, Alex

Publication type:

Article

Long‐term efficacy and safety of zoledronic acid in the treatment of skeletal metastases in patients with nonsmall cell lung carcinoma and other solid tumors: A randomized, Phase III, double‐blind, placebo‐controlled trial.

Published in:

Cancer (0008543X), 2004, v. 100, n. 12, p. 2613

By:

Lee S. Rosen;
David Gordon;
N. Simon Tchekmedyian;
Ronald Yanagihara;
Vera Hirsh;
Maciej Krzakowski;
Marek Pawlicki;
Paul de Souza;
Ming Zheng;
Gladys Urbanowitz;
Dirk Reitsma;
John Seaman

Publication type:

Article

Zoledronic acid is superior to pamidronate for the treatment of bone metastases in breast carcinoma patients with at least one osteolytic lesion.

Published in:

Cancer (0008543X), 2004, v. 100, n. 1, p. 36, doi. 10.1002/cncr.11892

By:

Lee S. Rosen;
David H. Gordon;
William Dugan;
Pierre Major;
Peter D. Eisenberg;
Louise Provencher;
Mary Kaminski;
Joe Simeone;
John Seaman;
Bee-Lian Chen;
Robert E. Coleman

Publication type:

Article

Long-term efficacy and safety of zoledronic acid compared with pamidronate disodium in the treatment of skeletal complications in patients with advanced multiple myeloma or breast carcinoma(Performed on behalf of the Zoledronic Acid Breast Cancer and Multiple Myeloma Study Group)

Published in:

Cancer (0008543X), 2003, v. 98, n. 8, p. 1735, doi. 10.1002/cncr.11701

By:

Lee S. Rosen;
David Gordon;
Mary Kaminski;
Anthony Howell;
Andrew Belch;
John Mackey;
Justus Apffelstaedt;
Mohamad A. Hussein;
Robert E. Coleman;
Dirk J. Reitsma;
Bee-Lian Chen;
John J. Seaman

Publication type:

Article

A phase I, dose-escalation study of PF-06650808, an anti-Notch3 antibody–drug conjugate, in patients with breast cancer and other advanced solid tumors.

Published in:

Investigational New Drugs, 2020, v. 38, n. 1, p. 120, doi. 10.1007/s10637-019-00754-y

By:

Rosen, Lee S.;
Wesolowski, Robert;
Baffa, Raffaele;
Liao, Kai-Hsin;
Hua, Steven Y.;
Gibson, Brenda L.;
Pirie-Shepherd, Steven;
Tolcher, Anthony W.

Publication type:

Article

Phase 1 and pharmacokinetic study of LY3007113, a p38 MAPK inhibitor, in patients with advanced cancer.

Published in:

Investigational New Drugs, 2018, v. 36, n. 4, p. 629, doi. 10.1007/s10637-017-0532-2

By:

Goldman, Jonathan W.;
Rosen, Lee S.;
Tolcher, Anthony W.;
Papadopoulos, Kyriakos;
Beeram, Muralidhar;
Shi, Peipei;
Pitou, Celine;
Bell, Robert;
Kulanthaivel, Palaniappan;
Zhang, Xuekui;
Fink, Aaron;
Chan, Edward M.;
Shahir, Ashwin;
Farrington, Daphne;
Patnaik, Amita

Publication type:

Article

A Phase I Multicenter Study of Continuous Oral Administration of Lonafarnib (SCH 66336) and Intravenous Gemcitabine in Patients With Advanced Cancer.

Published in:

Cancer Investigation, 2011, v. 29, n. 9, p. 617, doi. 10.3109/07357907.2011.621912

By:

Wong, Nan Soon;
Meadows, Kellen L.;
Rosen, Lee S.;
Adjei, Alex A.;
Kaufmann, Scott H.;
Morse, Michael A.;
Petros, William P.;
Zhu, Yali;
Statkevich, Paul;
Cutler, David L.;
Meyers, Michael L.;
Hurwitz, Herbert I.

Publication type:

Article

Bevacizumab in Colorectal Cancer: Current Role in Treatment and the Potential of Biosimilars.

Published in:

2017

By:

Rosen, Lee;
Jacobs, Ira;
Burkes, Ronald;
Rosen, Lee S;
Jacobs, Ira A;
Burkes, Ronald L

Publication type:

journal article