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An epithelial gene signature of trans-IL-6 signaling defines a subgroup of type 2-low asthma.
- Published in:
- Respiratory Research, 2023, v. 24, n. 1, p. 1, doi. 10.1186/s12931-023-02617-w
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- Publication type:
- Article
The Alzheimer's disease-linked protease BACE1 modulates neuronal IL-6 signaling through shedding of the receptor gp130.
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- Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00596-6
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- Publication type:
- Article
Crosstalk between microbiome, regulatory T cells and HCA2 orchestrates the inflammatory response in a murine psoriasis model.
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- Frontiers in Immunology, 2023, v. 14, p. 1, doi. 10.3389/fimmu.2023.1038689
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- Publication type:
- Article
Tetraspanin 8 Subfamily Members Regulate Substrate-Specificity of a Disintegrin and Metalloprotease 17.
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- Cells (2073-4409), 2022, v. 11, n. 17, p. 2683, doi. 10.3390/cells11172683
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- Publication type:
- Article
Single‐cell transcriptomics reveals a senescence‐associated IL‐6/CCR6 axis driving radiodermatitis.
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- EMBO Molecular Medicine, 2022, v. 14, n. 8, p. 1, doi. 10.15252/emmm.202115653
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- Article
Case Report: Arterial Wall Inflammation in Atherosclerotic Cardiovascular Disease is Reduced by Olamkicept (sgp130Fc).
- Published in:
- 2022
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- Publication type:
- Case Study
Identification of IL-6 Signalling Components as Predictors of Severity and Outcome in COVID-19.
- Published in:
- Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.891456
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- Publication type:
- Article
IL-6 Responsiveness of CD4 + and CD8 + T Cells after Allogeneic Stem Cell Transplantation Differs between Patients and Is Associated with Previous Acute Graft versus Host Disease and Pretransplant Antithymocyte Globulin Therapy.
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- Journal of Clinical Medicine, 2022, v. 11, n. 9, p. 2530, doi. 10.3390/jcm11092530
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- Article
Phagosomal signalling of the C-type lectin receptor Dectin-1 is terminated by intramembrane proteolysis.
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- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-29474-3
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- Article
Mechanisms of interorgan crosstalk in health and disease.
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- FEBS Letters, 2022, v. 596, n. 5, p. 529, doi. 10.1002/1873-3468.14313
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- Publication type:
- Article
Local and systemic effects of interleukin-6 (IL-6) in inflammation and cancer.
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- FEBS Letters, 2022, v. 596, n. 5, p. 557, doi. 10.1002/1873-3468.14220
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- Publication type:
- Article
Roles for ADAM17 in TNF-R1 Mediated Cell Death and Survival in Human U937 and Jurkat Cells.
- Published in:
- Cells (2073-4409), 2021, v. 10, n. 11, p. 3100, doi. 10.3390/cells10113100
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- Publication type:
- Article
Brain-Restricted Inhibition of IL-6 Trans-Signaling Mildly Affects Metabolic Consequences of Maternal Obesity in Male Offspring.
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- Nutrients, 2021, v. 13, n. 11, p. 3735, doi. 10.3390/nu13113735
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- Publication type:
- Article
Identification of the factor XII contact activation site enables sensitive coagulation diagnostics.
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- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-25888-7
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- Publication type:
- Article
The two facets of gp130 signalling in liver tumorigenesis.
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- Seminars in Immunopathology, 2021, v. 43, n. 4, p. 609, doi. 10.1007/s00281-021-00861-0
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- Publication type:
- Article
Oncostatin M induces hyperalgesic priming and amplifies signaling of cAMP to ERK by RapGEF2 and PKA.
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- Journal of Neurochemistry, 2021, v. 157, n. 6, p. 1821, doi. 10.1111/jnc.15172
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- Publication type:
- Article
Natural Glycoforms of Human Interleukin 6 Show Atypical Plasma Clearance.
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- Angewandte Chemie, 2021, v. 133, n. 24, p. 13492, doi. 10.1002/ange.202101496
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- Publication type:
- Article
Natural Glycoforms of Human Interleukin 6 Show Atypical Plasma Clearance.
- Published in:
- Angewandte Chemie International Edition, 2021, v. 60, n. 24, p. 13380, doi. 10.1002/anie.202101496
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- Publication type:
- Article
The role of interleukin-6 trans-signalling on cardiovascular dysfunction in inflammatory arthritis.
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- Rheumatology, 2021, v. 60, n. 6, p. 2852, doi. 10.1093/rheumatology/keaa725
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- Publication type:
- Article
Initiation of Pancreatic Cancer: The Interplay of Hyperglycemia and Macrophages Promotes the Acquisition of Malignancy-Associated Properties in Pancreatic Ductal Epithelial Cells.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 10, p. 5086, doi. 10.3390/ijms22105086
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- Publication type:
- Article
Transgenic inhibition of interleukin-6 trans-signaling does not prevent skeletal pathologies in mucolipidosis type II mice.
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- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-82802-3
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- Publication type:
- Article
ADAM17 Deficiency Protects against Pulmonary Emphysema.
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- American Journal of Respiratory Cell & Molecular Biology, 2021, v. 64, n. 2, p. 183, doi. 10.1165/rcmb.2020-0214OC
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- Publication type:
- Article
NOTCH Activation via gp130/STAT3 Signaling Confers Resistance to Chemoradiotherapy.
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- Cancers, 2021, v. 13, n. 3, p. 455, doi. 10.3390/cancers13030455
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- Publication type:
- Article
Cathepsin S provokes interleukin-6 (IL-6) trans-signaling through cleavage of the IL-6 receptor in vitro.
- Published in:
- Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-77884-4
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- Publication type:
- Article
Functional Characterization of Colon-Cancer-Associated Variants in ADAM17 Affecting the Catalytic Domain.
- Published in:
- Biomedicines, 2020, v. 8, n. 11, p. 463, doi. 10.3390/biomedicines8110463
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- Publication type:
- Article
ADAM-Mediated Signalling Pathways in Gastrointestinal Cancer Formation.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 14, p. 5133, doi. 10.3390/ijms21145133
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- Publication type:
- Article
IL-6 Trans-Signaling in the Brain Influences the Metabolic Phenotype of the 3xTg-AD Mouse Model of Alzheimer's Disease.
- Published in:
- Cells (2073-4409), 2020, v. 9, n. 7, p. 1605, doi. 10.3390/cells9071605
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- Publication type:
- Article
A variant in IL6ST with a selective IL-11 signaling defect in human and mouse.
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- Bone Research, 2020, v. 8, n. 1, p. 1, doi. 10.1038/s41413-020-0098-z
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- Publication type:
- Article
Tocilizumab does not block interleukin-6 (IL-6) signaling in murine cells.
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- PLoS ONE, 2020, v. 15, n. 5, p. 1, doi. 10.1371/journal.pone.0232612
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- Publication type:
- Article
The ADAM17 protease promotes tobacco smoke carcinogen-induced lung tumorigenesis.
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- Carcinogenesis, 2020, v. 41, n. 4, p. 527, doi. 10.1093/carcin/bgz123
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- Publication type:
- Article
Degradome of soluble ADAM10 and ADAM17 metalloproteases.
- Published in:
- Cellular & Molecular Life Sciences, 2020, v. 77, n. 2, p. 331, doi. 10.1007/s00018-019-03184-4
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- Publication type:
- Article
ADAM17 Activity and IL-6 Trans-Signaling in Inflammation and Cancer.
- Published in:
- Cancers, 2019, v. 11, n. 11, p. 1736, doi. 10.3390/cancers11111736
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- Publication type:
- Article
Meprin β induces activities of A disintegrin and metalloproteinases 9, 10, and 17 by specific prodomain cleavage.
- Published in:
- FASEB Journal, 2019, v. 33, n. 11, p. 11925, doi. 10.1096/fj.201801371R
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- Publication type:
- Article
Regulation of Fibrotic Processes in the Liver by ADAM Proteases.
- Published in:
- Cells (2073-4409), 2019, v. 8, n. 10, p. 1226, doi. 10.3390/cells8101226
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- Publication type:
- Article
ADAM17: An Emerging Therapeutic Target for Lung Cancer.
- Published in:
- Cancers, 2019, v. 11, n. 9, p. 1218, doi. 10.3390/cancers11091218
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- Publication type:
- Article
Differences in Shedding of the Interleukin-11 Receptor by the Proteases ADAM9, ADAM10, ADAM17, Meprin α, Meprin β and MT1-MMP.
- Published in:
- International Journal of Molecular Sciences, 2019, v. 20, n. 15, p. 3677, doi. 10.3390/ijms20153677
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- Publication type:
- Article
The Synthetic Retinoid Acitretin Increases IL-6 in the Central Nervous System of Alzheimer Disease Model Mice and Human Patients.
- Published in:
- Frontiers in Aging Neuroscience, 2019, p. 1, doi. 10.3389/fnagi.2019.00182
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- Publication type:
- Article
Functional Characterization of Colon Cancer-Associated Mutations in ADAM17: Modifications in the Pro-Domain Interfere with Trafficking and Maturation.
- Published in:
- International Journal of Molecular Sciences, 2019, v. 20, n. 9, p. 2198, doi. 10.3390/ijms20092198
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- Publication type:
- Article
Impaired mechanical, heat, and cold nociception in a murine model of genetic TACE/ADAM17 knockdown.
- Published in:
- FASEB Journal, 2019, v. 33, n. 3, p. 4418, doi. 10.1096/fj.201801901R
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- Publication type:
- Article
Correction to: A new multiple trauma model of the mouse.
- Published in:
- 2019
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- Publication type:
- journal article
Interleukin 6 trans-signalling and risk of future cardiovascular events.
- Published in:
- Cardiovascular Research, 2019, v. 115, n. 1, p. 213, doi. 10.1093/cvr/cvy191
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- Publication type:
- Article
Laboratory diagnostics of murine blood for detection of mouse cytomegalovirus (MCMV)-induced hepatitis.
- Published in:
- Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-33167-7
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- Publication type:
- Article
Control of Listeria monocytogenes infection requires classical IL-6 signaling in myeloid cells.
- Published in:
- PLoS ONE, 2018, v. 13, n. 8, p. 1, doi. 10.1371/journal.pone.0203395
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- Publication type:
- Article
Pharmacological inhibition of IL-6 trans-signaling improves compromised fracture healing after severe trauma.
- Published in:
- Naunyn-Schmiedeberg's Archives of Pharmacology, 2018, v. 391, n. 5, p. 523, doi. 10.1007/s00210-018-1483-7
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- Publication type:
- Article
BATF-dependent IL-7RhiGM-CSF+ T cells control intestinal graft-versus-host disease.
- Published in:
- 2018
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- Publication type:
- journal article
Differing Outcome of Experimental Autoimmune Encephalitis in Macrophage/Neutrophil- and T Cell-Specific gp130-Deficient Mice.
- Published in:
- Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2018.00836
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- Publication type:
- Article
Frontline Science: Proliferation of Ly6C<sup>+</sup> monocytes during urinary tract infections is regulated by IL‐6 trans‐signaling.
- Published in:
- Journal of Leukocyte Biology, 2018, v. 103, n. 1, p. 13, doi. 10.1189/jlb.3HI0517-198R
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- Publication type:
- Article
A new multiple trauma model of the mouse.
- Published in:
- 2017
- By:
- Publication type:
- journal article
Suppressor of Cytokine Signaling 3 in Macrophages Prevents Exacerbated Interleukin-6-Dependent Arginase-1 Activity and Early Permissiveness to Experimental Tuberculosis.
- Published in:
- Frontiers in Immunology, 2017, p. 1, doi. 10.3389/fimmu.2017.01537
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- Publication type:
- Article
Model Based Targeting of IL-6-Induced Inflammatory Responses in Cultured Primary Hepatocytes to Improve Application of the JAK Inhibitor Ruxolitinib.
- Published in:
- Frontiers in Physiology, 2017, p. 1, doi. 10.3389/fphys.2017.00775
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- Publication type:
- Article