Works matching AU Rood, Julian I.

Results: 42

The Anti-Sigma Factor TcdC Modulates Hypervirulence in an Epidemic BI/NAP1/027 Clinical Isolate of Clostridium difficile.

Published in:

PLoS Pathogens, 2011, v. 7, n. 10, p. 1, doi. 10.1371/journal.ppat.1002317

By:

Carter, Glen P.;
Douce, Gillian R.;
Govind, Revathi;
Howarth, Pauline M.;
Mackin, Kate E.;
Spencer, Janice;
Buckley, Anthony M.;
Antunes, Ana;
Kotsanas, Despina;
Jenkin, Grant A.;
Dupuy, Bruno;
Rood, Julian I.;
Lyras, Dena

Publication type:

Article

Programmed Cellular Necrosis Mediated by the Pore-Forming α-Toxin from Clostridium septicum.

Published in:

PLoS Pathogens, 2009, v. 5, n. 7, p. 1, doi. 10.1371/journal.ppat.1000516

By:

Kennedy, Catherine L.;
Smith, Danielle J.;
Lyras, Dena;
Chakravorty, Anjana;
Rood, Julian I.

Publication type:

Article

Molecular and Cellular Basis of Microvascular Perfusion Deficits Induced by Clostridium perfringens and Clostridium septicum.

Published in:

PLoS Pathogens, 2008, v. 4, n. 4, p. 1, doi. 10.1371/journal.ppat.1000045

By:

Hickey, Michael J.;
Kwan, Rain Y. Q.;
Awad, Milena M.;
Kennedy, Catherine L.;
Young, Lauren F.;
Hall, Pam;
Cordner, Leanne M.;
Lyras, Dena;
Emmins, John J.;
Rood, Julian I.

Publication type:

Article

NetB, a New Toxin That Is Associated with Avian Necrotic Enteritis Caused by Clostridium perfringens.

Published in:

PLoS Pathogens, 2008, v. 4, n. 2, p. 0001, doi. 10.1371/journal.ppat.0040026

By:

Keyburn, Anthony L.;
Boyce, John D.;
Vaz, Paola;
Bannam, Trudi L.;
Ford, Mark E.;
Parker, Dane;
Di Rubbo, Antonio;
Rood, Julian I.;
Moore, Robert J.

Publication type:

Article

Chloramphenicol-resistant Neisseria meningitidis containing catP isolated in Australia.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2003, v. 52, n. 5, p. 856, doi. 10.1093/jac/dkg452

By:

Tiffany R. Shultz;
John W. Tapsall;
Peter A. White;
Catherine S. Ryan;
Dena Lyras;
Julian I. Rood;
Enzo Binotto;
Christopher J. L. Richardson

Publication type:

Article

The Pore-Forming α-Toxin from Clostridium septicum Activates the MAPK Pathway in a Ras-c-Raf-Dependent and Independent Manner.

Published in:

Toxins, 2015, v. 7, n. 2, p. 516, doi. 10.3390/toxins7020516

By:

Chakravorty, Anjana;
Awad, Milena M.;
Cheung, Jackie K.;
Hiscox, Thomas J.;
Lyras, Dena;
Rood, Julian I.

Publication type:

Article

NanR, a Transcriptional Regulator That Binds to the Promoters of Genes Involved in Sialic Acid Metabolism in the Anaerobic Pathogen Clostridium perfringens.

Published in:

PLoS ONE, 2015, v. 10, n. 7, p. 1, doi. 10.1371/journal.pone.0133217

By:

Therit, Blair;
Cheung, Jackie K.;
Rood, Julian I.;
Melville, Stephen B.

Publication type:

Article

Spo0A Differentially Regulates Toxin Production in Evolutionarily Diverse Strains of Clostridium difficile.

Published in:

PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0079666

By:

Mackin, Kate E.;
Carter, Glen P.;
Howarth, Pauline;
Rood, Julian I.;
Lyras, Dena

Publication type:

Article

Regulation of Sialidase Production in Clostridium perfringens by the Orphan Sensor Histidine Kinase ReeS.

Published in:

PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0073525

By:

Hiscox, Thomas J.;
Harrison, Paul F.;
Chakravorty, Anjana;
Choo, Jocelyn M.;
Ohtani, Kaori;
Shimizu, Tohru;
Cheung, Jackie K.;
Rood, Julian I.

Publication type:

Article

The AprV5 Subtilase Is Required for the Optimal Processing of All Three Extracellular Serine Proteases from Dichelobacter nodosus.

Published in:

PLoS ONE, 2012, v. 7, n. 10, p. 1, doi. 10.1371/journal.pone.0047932

By:

Xiaoyan Han;
Kennan, Ruth M.;
Steer, David L.;
Smith, A. Ian;
Whisstock, James C.;
Rood, Julian I.

Publication type:

Article

The Cysteine Protease &agr;-Clostripain is Not Essential for the Pathogenesis of Clostridium perfringens-Mediated Myonecrosis.

Published in:

PLoS ONE, 2011, v. 6, n. 7, p. 1, doi. 10.1371/journal.pone.0022762

By:

Chakravorty, Anjana;
Awad, Milena M.;
Hiscox, Thomas J.;
Cheung, Jackie K.;
Carter, Glen P.;
Choo, Jocelyn M.;
Lyras, Dena;
Rood, Julian I.

Publication type:

Article

Functional Analysis of the VirSR Phosphorelay from Clostridium perfringens.

Published in:

PLoS ONE, 2009, v. 4, n. 6, p. 1, doi. 10.1371/journal.pone.0005849

By:

Cheung, Jackie K.;
Awad, Milena M.;
McGowan, Sheena;
Rood, Julian I.

Publication type:

Article

Genome Sequence of the Saprophyte Leptospira biflexa Provides Insights into the Evolution of Leptospira and the Pathogenesis of Leptospirosis.

Published in:

PLoS ONE, 2008, v. 3, n. 2, p. 1, doi. 10.1371/journal.pone.0001607

By:

Picardeau, Mathieu;
Bulach, Dieter M.;
Bouchier, Christiane;
Zuerner, Richard L.;
Zidane, Nora;
Wilson, Peter J.;
Creno, Sophie;
Kuczek, Elizabeth S.;
Bommezzadri, Simona;
Davis, John C.;
McGrath, Annette;
Johnson, Matthew J.;
Boursaux-Eude, Caroline;
Seemann, Torsten;
Rouy, Zoé;
Coppel, Ross L.;
Rood, Julian I.;
Lajus, Aurélie;
Davies, John K.;
Médigue, Claudine

Publication type:

Article

The conjugation protein TcpC from Clostridium perfringens is structurally related to the type IV secretion system protein VirB8 from Gram-negative bacteria.

Published in:

Molecular Microbiology, 2012, v. 83, n. 2, p. 275, doi. 10.1111/j.1365-2958.2011.07930.x

By:

Porter, Corrine J.;
Bantwal, Radhika;
Bannam, Trudi L.;
Rosado, Carlos J.;
Pearce, Mary C.;
Adams, Vicki;
Lyras, Dena;
Whisstock, James C.;
Rood, Julian I.

Publication type:

Article

Beta toxin is essential for the intestinal virulence of Clostridium perfringens type C disease isolate CN3685 in a rabbit ileal loop model.

Published in:

Molecular Microbiology, 2008, v. 67, n. 1, p. 15, doi. 10.1111/j.1365-2958.2007.06007.x

By:

Sayeed, Sameera;
Uzal, Francisco A.;
Fisher, Derek J.;
Saputo, Juliann;
Vidal, Jorge E.;
Yue Chen;
Gupta, Phalguni;
Rood, Julian I.;
McClane, Bruce A.

Publication type:

Article

Construction and analysis of chromosomal Clostridium difficile mutants.

Published in:

Molecular Microbiology, 2006, v. 61, n. 5, p. 1335, doi. 10.1111/j.1365-2958.2006.05315.x

By:

O'Connor, Jennifer R.;
Lyras, Dena;
Farrow, Kylie A.;
Adams, Vicki;
Powell, David R.;
Hinds, Jason;
Cheung, Jackie K.;
Rood, Julian I.

Publication type:

Article

Two distinct regions of the large serine recombinase TnpX are required for DNA binding and biological function.

Published in:

Molecular Microbiology, 2006, v. 60, n. 3, p. 591, doi. 10.1111/j.1365-2958.2006.05120.x

By:

Adams, Vicki;
Lucet, Isabelle S.;
Tynan, Fleur E.;
Chiarezza, Martina;
Howarth, Pauline M.;
Kim, Jonathan;
Rossjohn, Jamie;
Lyras, Dena;
Rood, Julian I.

Publication type:

Article

The α-toxin of Clostridium septicum is essential for virulence.

Published in:

Molecular Microbiology, 2005, v. 57, n. 5, p. 1357, doi. 10.1111/j.1365-2958.2005.04774.x

By:

Kennedy, Catherine L.;
Krejany, Efrosinia O.;
Young, Lauren F.;
O'Connor, Jennifer R.;
Awad, Milena M.;
Boyd, Richard L.;
Emmins, John J.;
Lyras, Dena;
Rood, Julian I.

Publication type:

Article

DNA binding properties of TnpX indicate that different synapses are formed in the excision and integration of the Tn 4451 family.

Published in:

Molecular Microbiology, 2004, v. 53, n. 4, p. 1195, doi. 10.1111/j.1365-2958.2004.04198.x

By:

Adams, Vicki;
Lucet, Isabelle S.;
Lyras, Dena;
Rood, Julian I.

Publication type:

Article

The large resolvase TnpX is the only transposon-encoded protein required for transposition of the Tn 4451/ 3 family of integrative mobilizable elements.

Published in:

Molecular Microbiology, 2004, v. 51, n. 6, p. 1787, doi. 10.1111/j.1365-2958.2003.03950.x

By:

Lyras, Dena;
Adams, Vicki;
Lucet, Isabelle;
Rood, Julian I.

Publication type:

Article

Crystal structure of TcpK in complex with oriT DNA of the antibiotic resistance plasmid pCW3.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-06096-2

By:

Traore, Daouda A. K.;
Wisniewski, Jessica A.;
Flanigan, Sarena F.;
Conroy, Paul J.;
Panjikar, Santosh;
Mok, Yee-Foong;
Lao, Carmen;
Griffin, Michael D. W.;
Adams, Vicki;
Rood, Julian I.;
Whisstock, James C.

Publication type:

Article

TcpM: a novel relaxase that mediates transfer of large conjugative plasmids from Clostridium perfringens.

Published in:

Molecular Microbiology, 2016, v. 99, n. 5, p. 884, doi. 10.1111/mmi.13270

By:

Wisniewski, Jessica A.;
Traore, Daouda A.;
Bannam, Trudi L.;
Lyras, Dena;
Whisstock, James C.;
Rood, Julian I.

Publication type:

Article

NetB and necrotic enteritis: the hole movable story.

Published in:

Avian Pathology, 2016, v. 45, n. 3, p. 295, doi. 10.1080/03079457.2016.1158781

By:

Rood, Julian I.;
Keyburn, Anthony L.;
Moore, Robert J.

Publication type:

Article

RNA-seq analysis of virR and revR mutants of Clostridium perfringens.

Published in:

BMC Genomics, 2016, v. 17, p. 1, doi. 10.1186/s12864-016-2706-2

By:

Lee-Yean Low;
Harrison, Paul F.;
Ya-Hsun Lin;
Boyce, John D.;
Rood, Julian I.;
Cheung, Jackie K.

Publication type:

Article

Transposition of Tn4451 and Tn4453 involves a circular intermediate that forms a promoter for the large resolvase, TnpX.

Published in:

Molecular Microbiology, 2000, v. 38, n. 3, p. 588, doi. 10.1046/j.1365-2958.2000.02154.x

By:

Lyras, Dena;
Rood, Julian I.

Publication type:

Article

Tn4451 from Clostridium perfringens is a mobilizable transposon that encodes the functional Mob...

Published in:

Molecular Microbiology, 1998, v. 27, n. 3, p. 631, doi. 10.1046/j.1365-2958.1998.00712.x

By:

Crellin, Paul K.;
Rood, Julian I.

Publication type:

Article

A multiple site-specific DNA-inversion model for the control of 0mp1 phase and antigenic variation in Dlchelobacter nodosus.

Published in:

Molecular Microbiology, 1995, v. 17, n. 1, p. 183, doi. 10.1111/j.1365-2958.1995.mmi_17010183.x

By:

Moses, Eric K.;
Good, Robert T.;
Sinistaj, Meri;
Billington, Stephen J.;
Langford, Christopher J.;
Rood, Julian I.

Publication type:

Article

Molecular genetics of the chloramphenicol-resistance transposon Tn4451 from Clostridium perfringens: the TnpX site--specific recombinase excises a circular transposon molecule.

Published in:

Molecular Microbiology, 1995, v. 16, n. 3, p. 535, doi. 10.1111/j.1365-2958.1995.tb02417.x

By:

Bannam, Trudi L.;
Crellin, Paul K.;
Rood, Julian I.

Publication type:

Article

Virulence studies on chromosomal α--toxin and 0--toxin mutants constructed by allelic exchange provide genetic evidence for the essential role of α--toxin in Clostridium perfringens--mediated gas gangrene.

Published in:

Molecular Microbiology, 1995, v. 15, n. 2, p. 191, doi. 10.1111/j.1365-2958.1995.tb02234.x

By:

Awad, Milena M.;
Bryant, Amy E.;
Stevens, Dennis L.;
Rood, Julian I.

Publication type:

Article

Identification and molecular analysis of a locus that regulates extracellular toxin production in Clostridium perfringens.

Published in:

Molecular Microbiology, 1994, v. 12, n. 5, p. 761, doi. 10.1111/j.1365-2958.1994.tb01063.x

By:

Lyristis, Michael;
Bryant, Amy E.;
Sloan, Joan;
Awad, Milena M.;
Nisbet, Ian T.;
Stevens, Dennis L.;
Rood, Julian I.

Publication type:

Article

The Clostridium perfringens Tet P determinant comprises two overlapping genes: tetA(P), which mediates active tetracycline efflux, and tetB(P), which is related to the ribosomal protection family of tetracycline--resistance determinants.

Published in:

Molecular Microbiology, 1994, v. 11, n. 2, p. 403, doi. 10.1111/j.1365-2958.1994.tb00320.x

By:

Sloan, Joan;
McMurry, Laura M.;
Lyras, Dena;
Levy, Stuart B.;
Rood, Julian I.

Publication type:

Article

The NEAT Domain-Containing Proteins of Clostridium perfringens Bind Heme.

Published in:

PLoS ONE, 2016, v. 11, n. 9, p. 1, doi. 10.1371/journal.pone.0162981

By:

Choo, Jocelyn M.;
Cheung, Jackie K.;
Wisniewski, Jessica A.;
Steer, David L.;
Bulach, Dieter M.;
Hiscox, Thomas J.;
Chakravorty, Anjana;
Smith, A. Ian;
Gell, David A.;
Rood, Julian I.;
Awad, Milena M.

Publication type:

Article

CdtR Regulates TcdA and TcdB Production in Clostridium difficile.

Published in:

PLoS Pathogens, 2016, v. 12, n. 7, p. 1, doi. 10.1371/journal.ppat.1005758

By:

Lyon, Shelley A.;
Hutton, Melanie L.;
Rood, Julian I.;
Cheung, Jackie K.;
Lyras, Dena

Publication type:

Article

Vibrational spectroscopy combined with transcriptomic analysis for investigation of bacterial responses towards acid stress.

Published in:

Applied Microbiology & Biotechnology, 2018, v. 102, n. 1, p. 333, doi. 10.1007/s00253-017-8561-5

By:

Hlaing, Mya M.;
Wood, Bayden R.;
McNaughton, Don;
Rood, Julian I.;
Fox, Edward M.;
Augustin, Mary Ann

Publication type:

Article

Infectious disease: Listeria does it again.

Published in:

Nature, 2010, v. 464, n. 7292, p. 1138, doi. 10.1038/4641138a

By:

Rood, Julian I.

Publication type:

Article

Toxin B is essential for virulence of Clostridium difficile.

Published in:

2009

By:

Lyras, Dena;
O’Connor, Jennifer R.;
Howarth, Pauline M.;
Sambol, Susan P.;
Carter, Glen P.;
Phumoonna, Tongted;
Poon, Rachael;
Adams, Vicki;
Vedantam, Gayatri;
Johnson, Stuart;
Gerding, Dale N.;
Rood, Julian I.

Publication type:

Letter

Solution structure and DNA binding of the catalytic domain of the large serine resolvase TnpX.

Published in:

Journal of Molecular Recognition, 2015, v. 28, n. 5, p. 316, doi. 10.1002/jmr.2446

By:

Headey, Stephen J.;
Sivakumaran, Andrew;
Adams, Vicki;
Lyras, Dena;
Rood, Julian I.;
Scanlon, Martin J.;
Wilce, Matthew C. J.

Publication type:

Article

Two putative zinc metalloproteases contribute to the virulence of Clostridium perfringens strains that cause avian necrotic enteritis.

Published in:

Journal of Veterinary Diagnostic Investigation, 2020, v. 32, n. 2, p. 259, doi. 10.1177/1040638719898689

By:

Uzal, Francisco A.;
Navarro, Mauricio A.;
Hostetter, Jesse M.;
Wade, Ben;
Keyburn, Anthony L.;
Haring, Volker;
Ford, Mark;
Rood, Julian I.;
Moore, Robert J.

Publication type:

Article

Opioid Analgesics Stop the Development of Clostridial Gas Gangrene.

Published in:

Journal of Infectious Diseases, 2014, v. 210, n. 3, p. 483, doi. 10.1093/infdis/jiu101

By:

Chakravorty, Anjana;
Awad, Milena M.;
Hiscox, Thomas J.;
Cheung, Jackie K.;
Choo, Jocelyn M.;
Lyras, Dena;
Rood, Julian I.

Publication type:

Article

Whole genome analysis reveals the diversity and evolutionary relationships between necrotic enteritis-causing strains of <italic>Clostridium perfringens</italic>.

Published in:

BMC Genomics, 2018, v. 19, n. 1, p. 1, doi. 10.1186/s12864-018-4771-1

By:

Lacey, Jake A.;
Allnutt, Theodore R.;
Vezina, Ben;
Van, Thi Thu Hao;
Stent, Thomas;
Han, Xiaoyan;
Rood, Julian I.;
Wade, Ben;
Keyburn, Anthony L.;
Seemann, Torsten;
Chen, Honglei;
Haring, Volker;
Johanesen, Priscilla A.;
Lyras, Dena;
Moore, Robert J.

Publication type:

Article

Experimental acute Clostridium perfringens type D enterotoxemia in sheep is not characterized by specific renal lesions.

Published in:

Veterinary Pathology, 2023, v. 60, n. 4, p. 412, doi. 10.1177/03009858231171669

By:

Giannitti, Federico;
García, Jorge P.;
Adams, Vicki;
Armendano, Joaquín I.;
Beingesser, Juliann;
Rood, Julian I.;
Uzal, Francisco A.

Publication type:

Article

Cardiopulmonary Lesions in Sheep Produced by Experimental Acute Clostridium Perfringens Type D Enterotoxemia.

Published in:

Veterinary Pathology, 2021, v. 58, n. 1, p. 103, doi. 10.1177/0300985820965554

By:

Giannitti, Federico;
García, Jorge P.;
Rood, Julian I.;
Adams, Vicki;
Armendano, Joaquín I.;
Beingesser, Juliann;
Uzal, Francisco A.

Publication type:

Article