Works by Rongzhen Zhang

Results: 55

Association between Troponin Elevation and Decreased Myocardial Blood Flow Reserve in Patients without Obstructive Coronary Artery Disease.

Published in:

Cardiology, 2024, v. 149, n. 1, p. 40, doi. 10.1159/000534867

By:

Yang, Ning;
Zhang, Rongzhen;
Zhao, Chaoqun;
Sun, Bochen;
Wang, Biyu;
Song, Yuwei;
Qi, Shuhan;
Liu, Jianan;
Sun, Yujia;
Liu, Hui;
An, Huanhuan;
Zhang, Xingyue;
Xiang, Fei;
Yang, Qinghui;
Han, Wei

Publication type:

Article

Construction of Knowledge Graph for Animal Husbandry Laws and Regulations in China.

Published in:

Animal Husbandry & Feed Science (Inner Mongolia), 2023, v. 44, n. 3, p. 69, doi. 10.12160/j.issn.1672-5190.2023.03.010

By:

ZHANG Rongzhen;
MENG Xiaoyan;
LIU Xiaoxiao;
WANG Yang

Publication type:

Article

Moderate expression of the transcriptional regulator ALsR enhances acetoin production by Bacillus subtilis.

Published in:

Journal of Industrial Microbiology & Biotechnology, 2013, v. 40, n. 9, p. 1067, doi. 10.1007/s10295-013-1303-5

By:

Zhang, Xian;
Zhang, Rongzhen;
Bao, Teng;
Yang, Taowei;
Xu, Meijuan;
Li, Huazhong;
Xu, Zhenghong;
Rao, Zhiming

Publication type:

Article

Length-Dependence of Lymphatic Phasic Contractile Activity Under Isometric and Isobaric Conditions.

Published in:

Microcirculation, 2007, v. 14, n. 6, p. 613, doi. 10.1080/10739680701436160

By:

Rongzhen Zhang;
Gashev, Anatoliy A.;
Zawieja, David C.;
Lane, Megan M.;
Davis, Michael J.

Publication type:

Article

The Persistence of HIV Diversity, Transcription, and Nef Protein in Kaposi's Sarcoma Tumors during Antiretroviral Therapy.

Published in:

Viruses (1999-4915), 2022, v. 14, n. 12, p. 2774, doi. 10.3390/v14122774

By:

Nolan, David J.;
Rose, Rebecca;
Zhang, Rongzhen;
Leong, Alan;
Fogel, Gary B.;
Scholte, Larissa L. S.;
Bethony, Jeffrey M.;
Bracci, Paige;
Lamers, Susanna L.;
McGrath, Michael S.

Publication type:

Article

Systemic Innate Immune System Restoration as a Therapeutic Approach for Neurodegenerative Disease: Effects of NP001 on Amyotrophic Lateral Sclerosis (ALS) Progression.

Published in:

Biomedicines, 2024, v. 12, n. 10, p. 2362, doi. 10.3390/biomedicines12102362

By:

McGrath, Michael S.;
Zhang, Rongzhen;
Bracci, Paige M.;
Azhir, Ari;
Forrest, Bruce D.

Publication type:

Article

Regulation of the Innate Immune System as a Therapeutic Approach to Supporting Respiratory Function in ALS.

Published in:

Cells (2073-4409), 2023, v. 12, n. 7, p. 1031, doi. 10.3390/cells12071031

By:

McGrath, Michael S.;
Zhang, Rongzhen;
Bracci, Paige M.;
Azhir, Ari;
Forrest, Bruce D.

Publication type:

Article

The carbapenem resistance gene blaOXA-23 is disseminated by a conjugative plasmid containing the novel transposon Tn6681 in Acinetobacter johnsonii M19.

Published in:

Antimicrobial Resistance & Infection Control, 2020, v. 9, n. 1, p. N.PAG, doi. 10.1186/s13756-020-00832-4

By:

Zong, Gongli;
Zhong, Chuanqing;
Fu, Jiafang;
Zhang, Yu;
Zhang, Peipei;
Zhang, Wenchi;
Xu, Yan;
Cao, Guangxiang;
Zhang, Rongzhen

Publication type:

Article

Temporal Variation and Spatial Distribution in the Water Environment Helps Explain Seasonal Dynamics of Zooplankton in River-Type Reservoir.

Published in:

Sustainability (2071-1050), 2022, v. 14, n. 21, p. 13719, doi. 10.3390/su142113719

By:

Yin, Jingyun;
Xia, Jihong;
Xia, Zhichang;
Cai, Wangwei;
Liu, Zewen;
Xu, Kejun;
Wang, Yue;
Zhang, Rongzhen;
Dong, Xu

Publication type:

Article

Coexpression of a carbonyl reductase and glucose 6-phosphate dehydrogenase in Pichia pastoris improves the production of (S)-1-phenyl-1,2-ethanediol.

Published in:

Biocatalysis & Biotransformation, 2011, v. 29, n. 5, p. 172, doi. 10.3109/10242422.2011.594881

By:

Geng, Yawei;
Zhang, Rongzhen;
Xu, Yan;
Wang, Shanshan;
Sha, Chong;
Xiao, Rong

Publication type:

Article

Enhancement of glucose production from maltodextrin hydrolysis by optimisation of saccharification process using mixed enzymes involving novel pullulanase.

Published in:

International Journal of Food Science & Technology, 2015, v. 50, n. 12, p. 2672, doi. 10.1111/ijfs.12939

By:

Zhao, Weichao;
Nie, Yao;
Mu, Xiaoqing;
Zhang, Rongzhen;
Xu, Yan

Publication type:

Article

The underlying mechanisms of Jie-Du-Hua-Yu granule for protecting rat liver failure.

Published in:

Drug Design, Development & Therapy, 2019, v. 13, p. 589, doi. 10.2147/DDDT.S180969

By:

Qiu, Hua;
Mao, Dewen;
Tang, Nong;
Long, Fuli;
Zhang, Rongzhen;
Wang, Minggang;
Shi, Qinglan;
Li, Jiahuan;
Jiang, Qin;
Chen, Yueqiao;
Wang, Xiufeng

Publication type:

Article

Phase 2B randomized controlled trial of NP001 in amyotrophic lateral sclerosis: Pre‐specified and post hoc analyses.

Published in:

Muscle & Nerve, 2022, v. 66, n. 1, p. 39, doi. 10.1002/mus.27511

By:

Miller, Robert G.;
Zhang, Rongzhen;
Bracci, Paige M.;
Azhir, Ari;
Barohn, Richard;
Bedlack, Richard;
Benatar, Michael;
Berry, James D.;
Cudkowicz, Merit;
Kasarskis, Edward J.;
Mitsumoto, Hiroshi;
Manousakis, Georgios;
Walk, David;
Oskarsson, Bjorn;
Shefner, Jeremy;
McGrath, Michael S.

Publication type:

Article

Utility of an Archival Dried Blood Spot (DBS) Collection from HIV-Infected Individuals with and without Cancer in a Resource-Limited Setting.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 19, p. 10235, doi. 10.3390/ijms251910235

By:

Zhang, Rongzhen;
Bracci, Paige M.;
Leong, Alan;
Rapp, Cassandra;
McGrath, Michael S.

Publication type:

Article

Optimized expression of ( S)-carbonyl reductase in Pichia pastoris for efficient production of ( S)-1-phenyl-1, 2-ethanediol.

Published in:

Journal of Basic Microbiology, 2014, v. 54, n. 8, p. 873, doi. 10.1002/jobm.201200780

By:

Zhang, Rongzhen;
Xu, Yan;
Xiao, Rong;
Wang, Lei;
Zhang, Botao

Publication type:

Article

Postmortem study of organ-specific toxicity in glioblastoma patients treated with a combination of temozolomide, irinotecan and bevacizumab.

Published in:

Journal of Neuro-Oncology, 2022, v. 160, n. 1, p. 221, doi. 10.1007/s11060-022-04144-y

By:

Lu, Guangrong;
Zhu, Ping;
Rao, Mayank;
Linendoll, Nadine;
Buja, L. Maximilian;
Bhattacharjee, Meenakshi B.;
Brown, Robert E.;
Ballester, Leomar Y.;
Tian, Xuejun;
Pilichowska, Monika;
Wu, Julian K.;
Hergenroeder, Georgene W.;
Glass, Williams F.;
Chen, Lei;
Zhang, Rongzhen;
Pillai, Anil K.;
Hunter, Robert L.;
Zhu, Jay-Jiguang

Publication type:

Article

Aroma Compound Changes in the Jiangxiangxing Baijiu Solid-State Distillation Process: Description, Kinetic Characters and Cut Point Selection.

Published in:

Foods, 2024, v. 13, n. 2, p. 232, doi. 10.3390/foods13020232

By:

Gao, Yuchen;
Yang, Qiang;
Jin, Guangyuan;
Yang, Shengzhi;
Qin, Ruiyang;
Lyu, Linjie;
Yao, Xianze;
Zhang, Rongzhen;
Chen, Shuang;
Xu, Yan

Publication type:

Article

NP001 regulation of macrophage activation markers in ALS: A phase I clinical and biomarker study.

Published in:

Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration, 2014, v. 15, n. 7/8, p. 601, doi. 10.3109/21678421.2014.951940

By:

Miller, Robert G.;
Zhang, Rongzhen;
Block, Gilbert;
Katz, Jonathan;
Barohn, Richard;
Kasarskis, Edward;
Forshew, Dallas;
Gopalakrishnan, Vidhya;
McGrath, Michael S.

Publication type:

Article

Delineation and Analysis of Regional Geochemical Anomaly Using the Object-Oriented Paradigm and Deep Graph Learning—A Case Study in Southeastern Inner Mongolia, North China.

Published in:

Applied Sciences (2076-3417), 2022, v. 12, n. 19, p. 10029, doi. 10.3390/app121910029

By:

Zhao, Bo;
Zhang, Dehui;
Zhang, Rongzhen;
Li, Zhu;
Tang, Panpan;
Wan, Haoming

Publication type:

Article

Neonatal tetanus incidence in China, 1996–2001, and risk factors for neonatal tetanus, Guangxi Province, China.

Published in:

International Journal of Epidemiology, 2004, v. 33, n. 3, p. 551, doi. 10.1093/ije/dyh073

By:

Feng Chai;
D Rebecca Prevots;
Xiaojun Wang;
Maureen Birmingham;
Rongzhen Zhang

Publication type:

Article

Treatment satisfaction with paliperidone extended-release tablets: open-label study in schizophrenia patients dissatisfied with previous antipsychotic medication.

Published in:

Neuropsychiatric Disease & Treatment, 2017, v. 13, p. 1089, doi. 10.2147/NDT.S130483

By:

Fu De Yang;
Juan Li;
Yun Long Tan;
Wei Ye Liang;
Rongzhen Zhang;
Ning Wang;
Wei Feng;
Shangli Cai;
Jian Min Zhuo;
Li Li Zhang

Publication type:

Article

Effects of the Use of a Mallet during Bone Marrow Biopsy Collection on Specimen Quality: A Quality Improvement Project.

Published in:

Annals of Clinical & Laboratory Science, 2018, v. 48, n. 4, p. 517

By:

Mauzo, Shakuntala H.;
Golardi, Natalia;
Baxter, Aaron J.;
Sultana, Sadia;
Nguyen, Nghia D.;
Zhang, Rongzhen;
Kott, Marylee M.;
Zvavanjanja, Rodrick C.;
Lei Chen

Publication type:

Article

Mutation breeding of acetoin high producing Bacillus subtilis blocked in 2,3-butanediol dehydrogenase.

Published in:

World Journal of Microbiology & Biotechnology, 2013, v. 29, n. 10, p. 1783, doi. 10.1007/s11274-013-1339-8

By:

Zhang, Xian;
Zhang, Rongzhen;
Yang, Taowei;
Zhang, Jing;
Xu, Meijuan;
Li, Huazhong;
Xu, Zhenghong;
Rao, Zhiming

Publication type:

Article

Crystal structure of a carbonyl reductase from Candida parapsilosis with anti-Prelog stereospecificity.

Published in:

Protein Science: A Publication of the Protein Society, 2008, v. 17, n. 8, p. 1412, doi. 10.1110/ps.035089.108

By:

Zhang, Rongzhen;
Zhu, Guangyu;
Zhang, Wenchi;
Cao, Sheng;
Ou, Xianjin;
Li, Xuemei;
Bartlam, Mark;
Xu, Yan;
Zhang, Xuejun C.;
Rao, Zihe

Publication type:

Article

Oligomeric interactions maintain active‐site structure in a noncooperative enzyme family.

Published in:

EMBO Journal, 2022, v. 41, n. 17, p. 1, doi. 10.15252/embj.2021108368

By:

Li, Yaohui;
Zhang, Rongzhen;
Wang, Chi;
Forouhar, Farhad;
Clarke, Oliver B;
Vorobiev, Sergey;
Singh, Shikha;
Montelione, Gaetano T;
Szyperski, Thomas;
Xu, Yan;
Hunt, John F

Publication type:

Article

Efficient D-allulose synthesis under acidic conditions by auto-inducing expression of the tandem D-allulose 3-epimerase genes in Bacillus subtilis.

Published in:

Microbial Cell Factories, 2022, v. 21, n. 1, p. 1, doi. 10.1186/s12934-022-01789-2

By:

Hu, Mengkai;
Wei, Yuxia;
Zhang, Rongzhen;
Shao, Minglong;
Yang, Taowei;
Xu, Meijuan;
Zhang, Xian;
Rao, Zhiming

Publication type:

Article

Structure-based rational design of hydroxysteroid dehydrogenases for improving and diversifying steroid synthesis.

Published in:

Critical Reviews in Biotechnology, 2023, v. 43, n. 5, p. 770, doi. 10.1080/07388551.2022.2054770

By:

Liu, Zhiyong;
Zhang, Rongzhen;
Zhang, Wenchi;
Xu, Yan

Publication type:

Article

Use of elicitors to enhance or activate the antibiotic production in streptomyces.

Published in:

2022

By:

Zong, Gongli;
Fu, Jiafang;
Zhang, Peipei;
Zhang, Wenchi;
Xu, Yan;
Cao, Guangxiang;
Zhang, Rongzhen

Publication type:

Literature Review

Application of unsupervised learning of finite mixture models in ASTER VNIR data-driven land use classification.

Published in:

Journal of Spatial Science, 2021, v. 66, n. 1, p. 89, doi. 10.1080/14498596.2019.1570478

By:

Zhao, Bo;
Yang, Fan;
Zhang, Rongzhen;
Shen, Junping;
Pilz, Jürgen;
Zhang, Dehui

Publication type:

Article

Efficient one-step production of (S)-1-phenyl-1, 2-ethanediol from (R)-enantiomer plus NAD+-NADPH in-situ regeneration using engineered Escherichia coli.

Published in:

Microbial Cell Factories, 2012, v. 11, n. 1, p. 167, doi. 10.1186/1475-2859-11-167

By:

Rongzhen Zhang;
Yan Xu;
Rong Xiao;
Botao Zhang;
Lei Wang

Publication type:

Article

Biofunctionalized “Kiwifruit‐Assembly” of Oxidoreductases in Mesoporous ZnO/Carbon Nanoparticles for Efficient Asymmetric Catalysis.

Published in:

Advanced Materials, 2018, v. 30, n. 11, p. 1, doi. 10.1002/adma.201705443

By:

Zhang, Rongzhen;
Jiang, Jiawei;
Zhou, Junping;
Xu, Yan;
Xiao, Rong;
Xia, Xinhui;
Rao, Zhiming

Publication type:

Article

Production of d-Tagatose by Whole-Cell Conversion of Recombinant Bacillus subtilis in the Absence of Antibiotics.

Published in:

Biology (2079-7737), 2021, v. 10, n. 12, p. 1343, doi. 10.3390/biology10121343

By:

Zhang, Xian;
Lu, Ruiqi;
Wang, Qiang;
Hu, Mengkai;
Li, Zhiyue;
Xu, Meijuan;
Yang, Taowei;
Zhang, Rongzhen;
Rao, Zhiming

Publication type:

Article

Discovery of a High-Efficient Algicidal Bacterium against Microcystis aeruginosa Based on Examinations toward Culture Strains and Natural Bloom Samples.

Published in:

Toxins, 2023, v. 15, n. 3, p. 220, doi. 10.3390/toxins15030220

By:

Zhang, He;
Xie, Yan;
Zhang, Rongzhen;
Zhang, Zhongliang;
Hu, Xinglong;
Cheng, Yao;
Geng, Ruozhen;
Ma, Zengling;
Li, Renhui

Publication type:

Article

Study on Ore-forming Fluid of Shiyaogou Porphyry Molybdenum Deposit, Henan Province, China.

Published in:

Acta Geologica Sinica (English Edition), 2014, v. 88, p. 1206, doi. 10.1111/1755-6724.12379_70

By:

ZHANG, Rongzhen;
ZHANG, Dehui;
HOU, Hongxing

Publication type:

Article

Role of CO2 and CH4 in Hydrothermal Ore-forming System.

Published in:

Acta Geologica Sinica (English Edition), 2014, v. 88, p. 1208, doi. 10.1111/1755-6724.12379_71

By:

ZHANG, Rongzhen;
ZHANG, Dehui;
SONG, Yaohui

Publication type:

Article

In situ expression of (R)-carbonyl reductase rebalancing an asymmetric pathway improves stereoconversion efficiency of racemic mixture to (S)-phenyl-1,2-ethanediol in Candida parapsilosis CCTCC M203011.

Published in:

Microbial Cell Factories, 2016, v. 15, p. 143, doi. 10.1186/s12934-016-0539-y

By:

Rongzhen Zhang;
Lei Wang;
Yan Xu;
Hongbo Liang;
Xiaotian Zhou;
Jiawei Jiang;
Yaohui Li;
Rong Xiao;
Ye Ni

Publication type:

Article

Combining biosensor and metabolic network optimization strategies for enhanced l-threonine production in Escherichia coli.

Published in:

Biotechnology for Biofuels & Bioproducts, 2025, v. 18, n. 1, p. 1, doi. 10.1186/s13068-025-02640-7

By:

Zhao, Zhenqiang;
Zhu, Rongshuai;
Shi, Xuanping;
Yang, Fengyu;
Xu, Meijuan;
Shao, Minglong;
Zhang, Rongzhen;
Zhao, Youxi;
You, Jiajia;
Rao, Zhiming

Publication type:

Article

Establishment and validation of a nomogram model for riskprediction of hepatic encephalopathy: a retrospective analysis.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-47012-z

By:

Yao, Chun;
Huang, Liangjiang;
Wang, Meng;
Mao, Dewen;
Wang, Minggang;
Zheng, Jinghui;
Long, Fuli;
Huang, Jingjing;
Liu, Xirong;
Zhang, Rongzhen;
Xie, Jiacheng;
Cheng, Chen;
Yao, Fan;
Huang, Guochu

Publication type:

Article

Trend of electroconvulsive therapy use and its relationships with clinical characteristics from a large psychiatric center in China.

Published in:

Frontiers in Psychiatry, 2025, p. 1, doi. 10.3389/fpsyt.2025.1508044

By:

Li, Wei;
Hu, Na;
Gao, Xiaoxiao;
Song, Yanying;
Zhang, Rongzhen;
Sun, Shiyou;
Tong, Jinghui;
Shen, Yang;
Yu, Yongjun;
Yang, Kebing;
Chen, Yan;
Song, Jiaqi

Publication type:

Article

Emodin in cardiovascular disease: The role and therapeutic potential.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1070567

By:

Yuanyuan Guo;
Rongzhen Zhang;
Wenlan Li

Publication type:

Article

Liquid Refractive Index Sensor Based on Terahertz Metamaterials.

Published in:

Plasmonics, 2022, v. 17, n. 2, p. 457, doi. 10.1007/s11468-021-01499-2

By:

Zhang, Rongzhen;
Zhang, Rui;
Wang, Zhibin;
Li, Mengwei;
Li, Kewu

Publication type:

Article

Ile258Met mutation of Brucella melitensis 7α-hydroxysteroid dehydrogenase significantly enhances catalytic efficiency, cofactor affinity, and thermostability.

Published in:

Applied Microbiology & Biotechnology, 2021, v. 105, n. 9, p. 3573, doi. 10.1007/s00253-021-11299-7

By:

Liu, Zhiyong;
Zhang, Rongzhen;
Zhang, Wenchi;
Xu, Yan

Publication type:

Article

Efficient Whole-Cell Biocatalyst for Acetoin Production with NAD+ Regeneration System through Homologous Co-Expression of 2,3-Butanediol Dehydrogenase and NADH Oxidase in Engineered Bacillus subtilis.

Published in:

PLoS ONE, 2014, v. 9, n. 7, p. 1, doi. 10.1371/journal.pone.0102951

By:

Bao, Teng;
Zhang, Xian;
Rao, Zhiming;
Zhao, Xiaojing;
Zhang, Rongzhen;
Yang, Taowei;
Xu, Zhenghong;
Yang, Shangtian

Publication type:

Article

Efficicent (R)-Phenylethanol Production with Enantioselectivity-Alerted (S)-Carbonyl Reductase II and NADPH Regeneration.

Published in:

PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0083586

By:

Zhang, Rongzhen;
Zhang, Botao;
Xu, Yan;
Li, Yaohui;
Li, Ming;
Liang, Hongbo;
Xiao, Rong

Publication type:

Article

Efficient production of (S)-1-phenyl-1,2-ethanediol using xylan as co-substrate by a coupled multi-enzyme Escherichia coli system.

Published in:

Microbial Cell Factories, 2020, v. 19, n. 1, p. 1, doi. 10.1186/s12934-020-01344-x

By:

Rao, Junchao;
Zhang, Rongzhen;
Xu, Guanyu;
Li, Lihong;
Xu, Yan

Publication type:

Article

Efficient chiral synthesis by Saccharomyces cerevisiae spore encapsulation of Candida parapsilosis Glu228Ser/(S)-carbonyl reductase II and Bacillus sp. YX-1 glucose dehydrogenase in organic solvents.

Published in:

Microbial Cell Factories, 2019, v. 18, n. 1, p. N.PAG, doi. 10.1186/s12934-019-1137-6

By:

Rao, Jingxin;
Zhang, Rongzhen;
Liang, Hongbo;
Gao, Xiao-Dong;
Nakanishi, Hideki;
Xu, Yan

Publication type:

Article

Respiratory Function Improvement and Lifespan Extension Following Immunotherapy with NP001 Support the Concept That Amyotrophic Lateral Sclerosis (ALS) Is an Immuno-Neurologic Disease.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 9, p. 4349, doi. 10.3390/ijms26094349

By:

Zhang, Rongzhen;
Azhir, Ari;
McGrath, Michael S.

Publication type:

Article

Improved Production of (R)-1-phenyl-1,2-ethanediol by a Codon-optimized R-specific Carbonyl Reductase from Candida parapsilosis in Escherichia coli.

Published in:

Applied Biochemistry & Biotechnology, 2010, v. 160, n. 3, p. 868, doi. 10.1007/s12010-009-8528-9

By:

Rongzhen Zhang;
Yan Xu;
Yawei Geng;
Shanshan Wang;
Ying Sun;
Rong Xiao

Publication type:

Article

Metabolite profiling analysis of hepatitis B virus–induced liver cirrhosis patients with minimal hepatic encephalopathy using gas chromatography‐time‐of‐flight mass spectrometry and ultra‐performance liquid chromatography‐quadrupole‐time‐of‐flight mass spectrometry

Published in:

Biomedical Chromatography, 2023, v. 37, n. 1, p. 1, doi. 10.1002/bmc.5529

By:

Huang, Guochu;
Xie, Sheng;
Wang, Meng;
Mao, Dewen;
Huang, Guye;
Huang, Jingjing;
Liu, Xirong;
Zhang, Rongzhen;
Xie, Jiacheng;
Huang, Liang Jiang;
Cheng, Chen;
Yao, Fan;
Zhong, Yu;
Lin, Long;
Yao, Chun

Publication type:

Article

The high expression of Aspergillus pseudoglaucus protease in Escherichia coli for hydrolysis of soy protein and milk protein.

Published in:

Preparative Biochemistry & Biotechnology, 2018, v. 48, n. 8, p. 725, doi. 10.1080/10826068.2018.1508035

By:

Liu, Haiyan;
Zhang, Rongzhen;
Li, Lihong;
Zhou, Lixian;
Xu, Yan

Publication type:

Article