Works by Ronen, Sabrina M.

Results: 47

Monitoring response to a clinically relevant IDH inhibitor in glioma—Hyperpolarized 13C magnetic resonance spectroscopy approaches.

Published in:

Neuro-Oncology Advances, 2023, v. 5, n. 1, p. 1, doi. 10.1093/noajnl/vdad143

By:

Hong, Donghyun;
Kim, Yaewon;
Mushti, Chandrasekhar;
Minami, Noriaki;
Wu, Jing;
Cherukuri, Murali Krishna;
Swenson, Rolf E;
Vigneron, Daniel B;
Ronen, Sabrina M

Publication type:

Article

Magnetic Resonance (MR) Metabolic Imaging in Glioma.

Published in:

2015

By:

Chaumeil, Myriam M.;
Lupo, Janine M.;
Ronen, Sabrina M.

Publication type:

Other

Mutant IDH1 gliomas downregulate phosphocholine and phosphoethanolamine synthesis in a 2-hydroxyglutarate-dependent manner.

Published in:

Cancer & Metabolism, 2018, v. 6, p. 1, doi. 10.1186/s40170-018-0178-3

By:

Viswanath, Pavithra;
Radoul, Marina;
Izquierdo-Garcia, Jose Luis;
Luchman, Hema Artee;
Gregory Cairncross, J.;
Pieper, Russell O.;
Phillips, Joanna J.;
Ronen, Sabrina M.

Publication type:

Article

Macromolecular dynamic contrast-enhanced (DCE)-MRI detects reduced vascular permeability in a prostate cancer bone metastasis model following anti-platelet-derived growth factor receptor (PDGFR) therapy, indicating a drop in vascular endothelial growth factor receptor (VEGFR) activation

Published in:

Magnetic Resonance in Medicine, 2008, v. 60, n. 4, p. 822, doi. 10.1002/mrm.21727

By:

Dafni, Hagit;
Kim, Sun-Jin;
Bankson, James A.;
Sankaranarayanapillai, Madhuri;
Ronen, Sabrina M.

Publication type:

Article

The application of 13C NMR to the characterization of phospholipid metabolism in cells.

Published in:

Magnetic Resonance in Medicine, 1992, v. 25, n. 2, p. 384, doi. 10.1002/mrm.1910250219

By:

Ronen, Sabrina M.;
Degani, Hadassa

Publication type:

Article

Monitoring Histone Deacetylase Inhibition In Vivo: Noninvasive Magnetic Resonance Spectroscopy Method.

Published in:

Molecular Imaging, 2008, v. 7, n. 2, p. 92, doi. 10.2310/7290.2008.0011

By:

Sankaranarayanapillai, Madhuri;
Tong, William P.;
Qing Yuan;
Bankson, James A.;
Dafni, Hagit;
Bornmann, William G.;
Soghomonyan, Suren;
Pal, Ashutosh;
Ramirez, Marc S.;
Webb, Douglas;
Kaluarachchi, Kumaralal;
Gelovani, Juri G.;
Ronen, Sabrina M.

Publication type:

Article

Choline metabolism in malignant transformation.

Published in:

2011

By:

Glunde, Kristine;
Bhujwalla, Zaver M.;
Ronen, Sabrina M.

Publication type:

journal article

Imaging biomarkers of TERT or GABPB1 silencing in TERT-positive glioblastoma.

Published in:

Neuro-Oncology, 2022, v. 24, n. 11, p. 1898, doi. 10.1093/neuonc/noac112

By:

Minami, Noriaki;
Hong, Donghyun;
Stevers, Nicholas;
Barger, Carter J;
Radoul, Marina;
Hong, Chibo;
Chen, Lee;
Kim, Yaewon;
Batsios, Georgios;
Gillespie, Anne Marie;
Pieper, Russel O;
Costello, Joseph F;
Viswanath, Pavithra;
Ronen, Sabrina M

Publication type:

Article

Deuterium magnetic resonance spectroscopy enables noninvasive metabolic imaging of tumor burden and response to therapy in low-grade gliomas.

Published in:

Neuro-Oncology, 2022, v. 24, n. 7, p. 1101, doi. 10.1093/neuonc/noac022

By:

Taglang, Céline;
Batsios, Georgios;
Mukherjee, Joydeep;
Tran, Meryssa;
Gillespie, Anne Marie;
Hong, Donghyun;
Ronen, Sabrina M;
Luchman, Hema Artee;
Pieper, Russell O;
Viswanath, Pavithra

Publication type:

Article

Metabolic imaging detects elevated glucose flux through the pentose phosphate pathway associated with TERT expression in low-grade gliomas.

Published in:

Neuro-Oncology, 2021, v. 23, n. 9, p. 1509, doi. 10.1093/neuonc/noab093

By:

Viswanath, Pavithra;
Batsios, Georgios;
Ayyappan, Vinay;
Taglang, Céline;
Gillespie, Anne Marie;
Larson, Peder E Z;
Luchman, H Artee;
Costello, Joseph F;
Pieper, Russell O;
Ronen, Sabrina M

Publication type:

Article

METABOLIC IMAGING BIOMARKERS FOR MUTANT IDH1 GLIOMAS.

Published in:

Neuro-Oncology, 2014, v. 16, n. suppl_3, p. iii12, doi. 10.1093/neuonc/nou206.41

By:

Ronen, Sabrina M.;
Izquierdo-Garcia, Jose L.;
Chaumeil, Myriam M.;
Cai, Larry M.;
Phillips, Joanna J.;
Pieper, Russell O.

Publication type:

Article

Lactate dehydrogenase A silencing in IDH mutant gliomas.

Published in:

Neuro-Oncology, 2014, v. 16, n. 5, p. 686, doi. 10.1093/neuonc/not243

By:

Chesnelong, Charles;
Chaumeil, Myriam M.;
Blough, Michael D.;
Al-Najjar, Mohammad;
Stechishin, Owen D.;
Chan, Jennifer A.;
Pieper, Russell O.;
Ronen, Sabrina M.;
Weiss, Samuel;
Luchman, H. Artee;
Cairncross, J. Gregory

Publication type:

Article

Longitudinal evaluation of MPIO-labeled stem cell biodistribution in glioblastoma using high resolution and contrast-enhanced MR imaging at 14.1Tesla.

Published in:

Neuro-Oncology, 2012, v. 14, n. 8, p. 1050, doi. 10.1093/neuonc/nos126

By:

Chaumeil, Myriam M.;
Gini, Beatrice;
Yang, Huijun;
Iwanami, Akio;
Sukumar, Subramaniam;
Ozawa, Tomoko;
Pieper, Russel O.;
Mischel, Paul S.;
James, C. David;
Berger, Mitchel S.;
Ronen, Sabrina M.

Publication type:

Article

Reduced phosphocholine and hyperpolarized lactate provide magnetic resonance biomarkers of PI3K/Akt/mTOR inhibition in glioblastoma.

Published in:

Neuro-Oncology, 2012, v. 14, n. 3, p. 315, doi. 10.1093/neuonc/nor209

By:

Venkatesh, Humsa S.;
Chaumeil, Myriam M.;
Ward, Christopher S.;
Haas-Kogan, Daphne A.;
James, C. David;
Ronen, Sabrina M.

Publication type:

Article

Cellular and in vivo activity of a novel PI3K inhibitor, PX-866, against human glioblastoma.

Published in:

Neuro-Oncology, 2010, v. 12, n. 6, p. 559, doi. 10.1093/neuonc/nop058

By:

Koul, Dimpy;
Shen, Ruijun;
Kim, Yong-Wan;
Kondo, Yasuko;
Lu, Yiling;
Bankson, Jim;
Ronen, Sabrina M.;
Kirkpatrick, D. Lynn;
Powis, Garth;
Yung, W. K. Alfred

Publication type:

Article

HDAC inhibition in glioblastoma monitored by hyperpolarized 13C MRSI.

Published in:

NMR in Biomedicine, 2019, v. 32, n. 1, p. N.PAG, doi. 10.1002/nbm.4044

By:

Radoul, Marina;
Najac, Chloé;
Viswanath, Pavithra;
Mukherjee, Joydeep;
Kelly, Mark;
Gillespie, Anne Marie;
Chaumeil, Myriam M.;
Eriksson, Pia;
Delos Santos, Romelyn;
Pieper, Russell O.;
Ronen, Sabrina M.

Publication type:

Article

HR-MAS MRS of the pancreas reveals reduced lipid and elevated lactate and taurine associated with early pancreatic cancer.

Published in:

NMR in Biomedicine, 2014, v. 27, n. 11, p. 1361, doi. 10.1002/nbm.3198

By:

Wang, Alan S.;
Lodi, Alessia;
Rivera, Lee B.;
Izquierdo‐Garcia, Jose L.;
Firpo, Matthew A.;
Mulvihill, Sean J.;
Tempero, Margaret A.;
Bergers, Gabriele;
Ronen, Sabrina M.

Publication type:

Article

MR-detectable metabolic consequences of mitogen-activated protein kinase kinase (MEK) inhibition.

Published in:

NMR in Biomedicine, 2014, v. 27, n. 6, p. 700, doi. 10.1002/nbm.3109

By:

Lodi, Alessia;
Woods, Sarah M.;
Ronen, Sabrina M.

Publication type:

Article

Treatment with the MEK inhibitor U0126 induces decreased hyperpolarized pyruvate to lactate conversion in breast, but not prostate, cancer cells.

Published in:

NMR in Biomedicine, 2013, v. 26, n. 3, p. 299, doi. 10.1002/nbm.2848

By:

Lodi, Alessia;
Woods, Sarah M.;
Ronen, Sabrina M.

Publication type:

Article

Vascular patterning and permeability in prostate cancer models with differing osteogenic properties.

Published in:

NMR in Biomedicine, 2012, v. 25, n. 6, p. 843, doi. 10.1002/nbm.1800

By:

Dafni, Hagit;
Burghardt, Andrew J.;
Majumdar, Sharmila;
Navone, Nora M.;
Ronen, Sabrina M.

Publication type:

Article

Metabolic consequences of treatment with AKT inhibitor perifosine in breast cancer cells.

Published in:

NMR in Biomedicine, 2012, v. 25, n. 2, p. 379, doi. 10.1002/nbm.1764

By:

Su, Judy S.;
Woods, Sarah M.;
Ronen, Sabrina M.

Publication type:

Article

Magnetic resonance spectroscopic pharmacodynamic markers of the heat shock protein 90 inhibitor 17-allylamino,17-demethoxygeldanamycin (17AAG) in human colon cancer models.

Published in:

2003

By:

Chung, Yuen-Li;
Troy, Helen;
Banerji, Udai;
Jackson, Laura E;
Walton, Mike I;
Stubbs, Marion;
Griffiths, John R;
Judson, Ian R;
Leach, Martin O;
Workman, Paul;
Ronen, Sabrina M

Publication type:

journal article

Magnetic Resonance Spectroscopic Pharmacodynamic Markers of the Heat Shock Protein 90 Inhibitor 17-Allylamino,17-Demethoxygeldanamycin (17AAG) in Human Color Cancer Models.

Published in:

JNCI: Journal of the National Cancer Institute, 2003, v. 95, n. 21, p. 1624, doi. 10.1093/jnci/djg084

By:

Yuen-Li Chung, Aaron;
Troy, Helen;
Banerji, Udai;
Jackson, Laura E.;
Walton, Mike I.;
Stubbs, Marion;
Griffiths, John R.;
Judson, Ian R.;
Leach, Martin O.;
Workman, Paul;
Ronen, Sabrina M.

Publication type:

Article

In vivo detection of γ-glutamyl-transferase up-regulation in glioma using hyperpolarized γ-glutamyl-[1-13C]glycine.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-63160-y

By:

Batsios, Georgios;
Najac, Chloé;
Cao, Peng;
Viswanath, Pavithra;
Subramani, Elavarasan;
Saito, Yutaro;
Gillespie, Anne Marie;
Yoshihara, Hikari A. I.;
Larson, Peder;
Sando, Shinsuke;
Ronen, Sabrina M.

Publication type:

Article

PI3K/mTOR inhibition of IDH1 mutant glioma leads to reduced 2HG production that is associated with increased survival.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-47021-x

By:

Batsios, Georgios;
Viswanath, Pavithra;
Subramani, Elavarasan;
Najac, Chloe;
Gillespie, Anne Marie;
Santos, Romelyn Delos;
Molloy, Abigail R.;
Pieper, Russell O.;
Ronen, Sabrina M.

Publication type:

Article

Molecular imaging of Metabolic Reprograming in Mutant IDH Cells.

Published in:

Frontiers in Oncology, 2016, p. 1, doi. 10.3389/fonc.2016.00060

By:

Viswanath, Pavithra;
Chaumeil, Myriam M.;
Ronen, Sabrina M.

Publication type:

Article

Treatment of SW620 Cells with Tomudex and Oxaliplatin Induces Changes in 2-Deoxy-D-Glucose Incorporation Associated with Modifications in Glucose Transport.

Published in:

Journal of Nuclear Medicine, 2000, v. 41, n. 10, p. 1753

By:

Smith, Timothy A. D.;
Maisey, Nick R.;
Titley, Jennifer C.;
Jackson, L. Elizabeth;
Leach, Martin O.;
Ronen, Sabrina M.

Publication type:

Article

Detection of early response to temozolomide treatment in brain tumors using hyperpolarized 13C MR metabolic imaging.

Published in:

2011

By:

Park I;
Bok R;
Ozawa T;
Phillips JJ;
James CD;
Vigneron DB;
Ronen SM;
Nelson SJ;
Park, Ilwoo;
Bok, Robert;
Ozawa, Tomoko;
Phillips, Joanna J;
James, C David;
Vigneron, Daniel B;
Ronen, Sabrina M;
Nelson, Sarah J

Publication type:

journal article

Detection of early response to temozolomide treatment in brain tumors using hyperpolarized.

Published in:

Journal of Magnetic Resonance Imaging, 2011, v. 33, n. 6, p. 1284, doi. 10.1002/jmri.22563

By:

Park, Ilwoo;
Bok, Robert;
Ozawa, Tomoko;
Phillips, Joanna J.;
James, C. David;
Vigneron, Daniel B.;
Ronen, Sabrina M.;
Nelson, Sarah J.

Publication type:

Article

In vivo investigation of hyperpolarized [1,3-13C2]acetoacetate as a metabolic probe in normal brain and in glioma.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-39677-2

By:

Najac, Chloé;
Radoul, Marina;
Le Page, Lydia M.;
Batsios, Georgios;
Subramani, Elavarasan;
Viswanath, Pavithra;
Gillespie, Anne Marie;
Ronen, Sabrina M.

Publication type:

Article

Early Noninvasive Metabolic Biomarkers of Mutant IDH Inhibition in Glioma.

Published in:

Metabolites (2218-1989), 2021, v. 11, n. 2, p. 109, doi. 10.3390/metabo11020109

By:

Radoul, Marina;
Hong, Donghyun;
Gillespie, Anne Marie;
Najac, Chloé;
Viswanath, Pavithra;
Pieper, Russell O.;
Costello, Joseph F.;
Luchman, Hema Artee;
Ronen, Sabrina M.;
Martins, Andre F.

Publication type:

Article

Non-invasive in vivo assessment of IDH1 mutational status in glioma.

Published in:

Nature Communications, 2013, v. 4, n. 9, p. 2429, doi. 10.1038/ncomms3429

By:

Chaumeil, Myriam M.;
Larson, Peder E. Z.;
Yoshihara, Hikari A. I.;
Danforth, Olivia M.;
Vigneron, Daniel B.;
Nelson, Sarah J.;
Pieper, Russell O.;
Phillips, Joanna J.;
Ronen, Sabrina M.

Publication type:

Article

Acquisition and quantification pipeline for in vivo hyperpolarized 13C MR spectroscopy.

Published in:

Magnetic Resonance in Medicine, 2022, v. 87, n. 4, p. 1673, doi. 10.1002/mrm.29081

By:

Hong, Donghyun;
Batsios, Georgios;
Viswanath, Pavithra;
Gillespie, Anne Marie;
Vaidya, Manushka;
Larson, Peder E. Z.;
Ronen, Sabrina M.

Publication type:

Article

Accelerated high-bandwidth MR spectroscopic imaging using compressed sensing.

Published in:

Magnetic Resonance in Medicine, 2016, v. 76, n. 2, p. 369, doi. 10.1002/mrm.26272

By:

Cao, Peng;
Shin, Peter J.;
Park, Ilwoo;
Najac, Chloe;
Marco‐Rius, Irene;
Vigneron, Daniel B.;
Nelson, Sarah J.;
Ronen, Sabrina M.;
Larson, Peder E. Z.

Publication type:

Article

Rapid in vivo apparent diffusion coefficient mapping of hyperpolarized 13C metabolites.

Published in:

Magnetic Resonance in Medicine, 2015, v. 74, n. 3, p. 622, doi. 10.1002/mrm.25422

By:

Koelsch, Bertram L.;
Reed, Galen D.;
Keshari, Kayvan R.;
Chaumeil, Myriam M.;
Bok, Robert;
Ronen, Sabrina M.;
Vigneron, Daniel B.;
Kurhanewicz, John;
Larson, Peder E. Z.

Publication type:

Article

Evaluation of heterogeneous metabolic profile in an orthotopic human glioblastoma xenograft model using compressed sensing hyperpolarized 3D 13C magnetic resonance spectroscopic imaging.

Published in:

Magnetic Resonance in Medicine, 2013, v. 70, n. 1, p. 33, doi. 10.1002/mrm.24434

By:

Park, Ilwoo;
Hu, Simon;
Bok, Robert;
Ozawa, Tomoko;
Ito, Motokazu;
Mukherjee, Joydeep;
Phillips, Joanna J.;
James, C. David;
Pieper, Russell O.;
RonEN, Sabrina M.;
Vigneron, Daniel B.;
Nelson, Sarah J.

Publication type:

Article

Metabolic Profiling of IDH Mutation and Malignant Progression in Infiltrating Glioma.

Published in:

Scientific Reports, 2017, p. 44792, doi. 10.1038/srep44792

By:

Jalbert, Llewellyn E.;
Elkhaled, Adam;
Phillips, Joanna J.;
Neill, Evan;
Williams, Aurelia;
Crane, Jason C.;
Olson, Marram P.;
Molinaro, Annette M.;
Berger, Mitchel S.;
Kurhanewicz, John;
Ronen, Sabrina M.;
Chang, Susan M.;
Nelson, Sarah J.

Publication type:

Article

Detection of inflammatory cell function using 13C magnetic resonance spectroscopy of hyperpolarized [6-13C]-arginine.

Published in:

Scientific Reports, 2016, p. 31397, doi. 10.1038/srep31397

By:

Najac, Chloé;
Chaumeil, Myriam M.;
Kohanbash, Gary;
Guglielmetti, Caroline;
Gordon, Jeremy W.;
Okada, Hideho;
Ronen, Sabrina M.

Publication type:

Article

Imaging 6-Phosphogluconolactonase Activity in Brain Tumors In Vivo Using Hyperpolarized δ-[1-13C]gluconolactone.

Published in:

Frontiers in Oncology, 2021, v. 11, p. N.PAG, doi. 10.3389/fonc.2021.589570

By:

Batsios, Georgios;
Taglang, Céline;
Cao, Peng;
Gillespie, Anne Marie;
Najac, Chloé;
Subramani, Elavarasan;
Wilson, David M.;
Flavell, Robert R.;
Larson, Peder E. Z.;
Ronen, Sabrina M.;
Viswanath, Pavithra

Publication type:

Article

Non-invasive assessment of telomere maintenance mechanisms in brain tumors.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-020-20312-y

By:

Viswanath, Pavithra;
Batsios, Georgios;
Mukherjee, Joydeep;
Gillespie, Anne Marie;
Larson, Peder E. Z.;
Luchman, H. Artee;
Phillips, Joanna J.;
Costello, Joseph F.;
Pieper, Russell O.;
Ronen, Sabrina M.

Publication type:

Article

Metabolic Reprogramming in Mutant IDH1 Glioma Cells.

Published in:

PLoS ONE, 2015, v. 10, n. 2, p. 1, doi. 10.1371/journal.pone.0118781

By:

Izquierdo-Garcia, Jose L.;
Viswanath, Pavithra;
Eriksson, Pia;
Chaumeil, Myriam M.;
Pieper, Russell O.;
Phillips, Joanna J.;
Ronen, Sabrina M.

Publication type:

Article

Glioma Cells with the IDH1 Mutation Modulate Metabolic Fractional Flux through Pyruvate Carboxylase.

Published in:

PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0108289

By:

Izquierdo-Garcia, Jose L.;
Cai, Larry M.;
Chaumeil, Myriam M.;
Eriksson, Pia;
Robinson, Aaron E.;
Pieper, Russell O.;
Phillips, Joanna J.;
Ronen, Sabrina M.

Publication type:

Article

Early Chk1 Phosphorylation Is Driven by Temozolomide-Induced, DNA Double Strand Break- and Mismatch Repair-Independent DNA Damage

Published in:

PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0062351

By:

Ito, Motokazu;
Ohba, Shigeo;
Gaensler, Karin;
Ronen, Sabrina M.;
Mukherjee, Joydeep;
Pieper, Russell O.

Publication type:

Article

HDAC Inhibition Induces Increased Choline Uptake and Elevated Phosphocholine Levels in MCF7 Breast Cancer Cells.

Published in:

PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0062610

By:

Ward, Christopher S.;
Eriksson, Pia;
Izquierdo-Garcia, Jose L.;
Brandes, Alissa H.;
Ronen, Sabrina M.

Publication type:

Article

Pyruvate Kinase M2 Expression, but Not Pyruvate Kinase Activity, Is Up-Regulated in a Grade-Specific Manner in Human Glioma.

Published in:

PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0057610

By:

Mukherjee, Joydeep;
Phillips, Joanna J.;
Zheng, Shichun;
Wiencke, John;
Ronen, Sabrina M.;
Pieper, Russell O.

Publication type:

Article

Magnetic Resonance Spectroscopy Detectable Metabolomic Fingerprint of Response to Antineoplastic Treatment.

Published in:

PLoS ONE, 2011, v. 6, n. 10, p. 1, doi. 10.1371/journal.pone.0026155

By:

Lodi, Alessia;
Ronen, Sabrina M.

Publication type:

Article

Hyperpolarized δ-[1- 13C]gluconolactone imaging visualizes response to TERT or GABPB1 targeting therapy for glioblastoma.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-32463-1

By:

Minami, Noriaki;
Hong, Donghyun;
Taglang, Celine;
Batsios, Georgios;
Gillespie, Anne Marie;
Viswanath, Pavithra;
Stevers, Nicholas;
Barger, Carter J.;
Costello, Joseph F.;
Ronen, Sabrina M.

Publication type:

Article