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Allosteric inhibition of HTRA1 activity by a conformational lock mechanism to treat age-related macular degeneration.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32760-9
By:
- Gerhardy, Stefan;
- Ultsch, Mark;
- Tang, Wanjian;
- Green, Evan;
- Holden, Jeffrey K.;
- Li, Wei;
- Estevez, Alberto;
- Arthur, Chris;
- Tom, Irene;
- Rohou, Alexis;
- Kirchhofer, Daniel
Publication type:
Article
Analysis of Tau heterogeneity and proteome‐wide changes in Alzheimer's Disease at the single‐molecule level.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.077441
By:
- Guha, Sanjib K;
- Tan, Steven;
- Joly, James;
- Park, Deborah;
- Wang, Rosemary;
- Nortman, Brittany;
- Gillies, Taryn E.;
- Budamagunta, Vivek;
- Robinson, Julia K;
- Rinker, Torri Elise;
- Sherman, Jamie;
- Ellahi, Aisha;
- Wiederhold, Thorsten;
- Kirkpatrick, Don;
- Lipka, Johanna;
- Wendorff, Tim;
- Pandya, Nikil J;
- Rohou, Alexis;
- Kapp, Greg;
- Mallick, Parag
Publication type:
Article
Analysis of Tau heterogeneity and proteome‐wide changes in Alzheimer's Disease at the single‐molecule level.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.077441
By:
- Guha, Sanjib K;
- Tan, Steven;
- Joly, James;
- Park, Deborah;
- Wang, Rosemary;
- Nortman, Brittany;
- Gillies, Taryn E.;
- Budamagunta, Vivek;
- Robinson, Julia K;
- Rinker, Torri Elise;
- Sherman, Jamie;
- Ellahi, Aisha;
- Wiederhold, Thorsten;
- Kirkpatrick, Don;
- Lipka, Johanna;
- Wendorff, Tim;
- Pandya, Nikil J;
- Rohou, Alexis;
- Kapp, Greg;
- Mallick, Parag
Publication type:
Article
The Establishment of a Cryo-EM Facility and Workflows to Support Pipeline Projects at Genentech.
Published in:
Microscopy & Microanalysis, 2019, p. 1412, doi. 10.1017/S1431927618007547
By:
- Estevez, Alberto;
- Arthur, Chris;
- Rohou, Alexis;
- Ciferri, Claudio
Publication type:
Article
The Establishment of a Cryo-EM Facility and Workflows to Support Pipeline Projects at Genentech.
Published in:
2018
By:
- Estevez, Alberto;
- Arthur, Chris;
- Rohou, Alexis;
- Ciferri, Claudio
Publication type:
Abstract
Design of a High Capacity Puck Storage System for Cryo-EM grids in a Facility Setting.
Published in:
Microscopy & Microanalysis, 2017, v. 23, p. 846, doi. 10.1017/S1431927617004895
By:
- Estevez, Alberto;
- Arthur, Chris;
- Rohou, Alexis;
- Ciferri, Claudio
Publication type:
Article
Structures of autoinhibited and polymerized forms of CARD9 reveal mechanisms of CARD9 and CARD11 activation.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-10953-z
By:
- Holliday, Michael J.;
- Witt, Axel;
- Rodríguez Gama, Alejandro;
- Walters, Benjamin T.;
- Arthur, Christopher P.;
- Halfmann, Randal;
- Rohou, Alexis;
- Dueber, Erin C.;
- Fairbrother, Wayne J.
Publication type:
Article
α-Latrotoxin Tetramers Spontaneously Form Two-Dimensional Crystals in Solution and Coordinated Multi-Pore Assemblies in Biological Membranes.
Published in:
Toxins, 2024, v. 16, n. 6, p. 248, doi. 10.3390/toxins16060248
By:
- Rohou, Alexis;
- Morris, Edward P.;
- Makarova, Julia;
- Tonevitsky, Alexander G.;
- Ushkaryov, Yuri A.
Publication type:
Article
Cryo-EM reveals an unprecedented binding site for Na<sub>V</sub>1.7 inhibitors enabling rational design of potent hybrid inhibitors.
Published in:
eLife, 2023, p. 1, doi. 10.7554/eLife.84151
By:
- Kschonsak, Marc;
- Jao, Christine C.;
- Arthur, Christopher P.;
- Rohou, Alexis L.;
- Bergeron, Philippe;
- Ortwine, Daniel F.;
- McKerrall, Steven J.;
- Hackos, David H.;
- Lunbin Deng;
- Jun Chen;
- Tianbo Li;
- Dragovich, Peter S.;
- Volgraf, Matthew;
- Wright, Matthew R.;
- Payandeh, Jian;
- Ciferri, Claudio;
- Tellis, John C.
Publication type:
Article
Structure of the SLC4 transporter Bor1p in an inward-facing conformation.
Published in:
Protein Science: A Publication of the Protein Society, 2017, v. 26, n. 1, p. 130, doi. 10.1002/pro.3061
By:
- Coudray, Nicolas;
- L. Seyler, Sean;
- Lasala, Ralph;
- Zhang, Zhening;
- Clark, Kathy M.;
- Dumont, Mark E.;
- Rohou, Alexis;
- Beckstein, Oliver;
- Stokes, David L.
Publication type:
Article

Found: 10