Works by Roepman, Paul

Results: 33

Efficacy and Safety of Panitumumab in Patients With RAF/RAS-Wild-Type Glioblastoma: Results From the Drug Rediscovery Protocol.

Published in:

Oncologist, 2024, v. 29, n. 5, p. 431, doi. 10.1093/oncolo/oyad320

By:

Spiekman, Ilse A C;
Geurts, Birgit S;
Zeverijn, Laurien J;
Wit, Gijs F de;
van der Noort, Vincent;
Roepman, Paul;
Leng, Wendy W J de;
Jansen, Anne M L;
Kusters, Benno;
Beerepoot, Laurens V;
Vos, Filip Y F L de;
Groot, Derk-Jan A de;
Groot, Jan Willem B de;
Hoeben, Ann;
Buter, Jan;
Gelderblom, Hans A J;
Voest, Emile E;
Verheul, Henk M W

Publication type:

Article

Decreased expression of ABAT and STC2 hallmarks ER-positive inflammatory breast cancer and endocrine therapy resistance in advanced disease.

Published in:

Molecular Oncology, 2015, v. 9, n. 6, p. 1218, doi. 10.1016/j.molonc.2015.02.006

By:

Jansen, Maurice P.H.M.;
Sas, Leen;
Sieuwerts, Anieta M.;
Van Cauwenberghe, Caroline;
Ramirez-Ardila, Diana;
Look, Maxime;
Ruigrok-Ritstier, Kirsten;
Finetti, Pascal;
Bertucci, François;
Timmermans, Mieke M.;
van Deurzen, Carolien H.M.;
Martens, John W.M.;
Simon, Iris;
Roepman, Paul;
Linn, Sabine C.;
van Dam, Peter;
Kok, Marleen;
Lardon, Filip;
Vermeulen, Peter B.;
Foekens, John A.

Publication type:

Article

Impact of panel design and cut-off on tumour mutational burden assessment in metastatic solid tumour samples.

Published in:

British Journal of Cancer, 2020, v. 122, n. 7, p. 953, doi. 10.1038/s41416-020-0762-5

By:

Mankor, Joanne M.;
Paats, Marthe S.;
Groenendijk, Floris H.;
Roepman, Paul;
Dinjens, Winand N. M.;
Dubbink, Hendrikus J.;
Sleijfer, Stefan;
Cuppen, Edwin;
Lolkema, Martijn P. J. K.

Publication type:

Article

Impact of panel design and cut-off on tumour mutational burden assessment in metastatic solid tumour samples.

Published in:

2020

By:

Mankor, Joanne M.;
Paats, Marthe S.;
Groenendijk, Floris H.;
Roepman, Paul;
Dinjens, Winand N. M.;
Dubbink, Hendrikus J.;
Sleijfer, Stefan;
Cuppen, Edwin;
Lolkema, Martijn P. J. K.;
CPCT Consortium

Publication type:

journal article

VIRUSBreakend: Viral Integration Recognition Using Single Breakends.

Published in:

Bioinformatics, 2021, v. 37, n. 19, p. 3115, doi. 10.1093/bioinformatics/btab343

By:

Cameron, Daniel L;
Jacobs, Nina;
Roepman, Paul;
Priestley, Peter;
Cuppen, Edwin;
Papenfuss, Anthony T

Publication type:

Article

Study protocol: Whole genome sequencing Implementation in standard Diagnostics for Every cancer patient (WIDE).

Published in:

BMC Medical Genomics, 2020, v. 13, n. 1, p. N.PAG, doi. 10.1186/s12920-020-00814-w

By:

Samsom, Kris G.;
Bosch, Linda J. W.;
Schipper, Luuk J.;
Roepman, Paul;
de Bruijn, Ewart;
Hoes, Louisa R.;
Riethorst, Immy;
Schoenmaker, Lieke;
van der Kolk, Lizet E.;
Retèl, Valesca P.;
Frederix, Geert W. J.;
Buffart, Tineke E.;
van der Hoeven, Jacobus J. M.;
Voest, Emile E.;
Cuppen, Edwin;
Monkhorst, Kim;
Meijer, Gerrit A.

Publication type:

Article

An expression profile for diagnosis of lymph node metastases from primary head and neck squamous cell carcinomas.

Published in:

Nature Genetics, 2005, v. 37, n. 2, p. 182, doi. 10.1038/ng1502

By:

Roepman, Paul;
Wessels, Lodewyk F. A.;
Kettelarij, Nienke;
Kemmeren, Patrick;
Miles, Antony J.;
Lijnzaad, Philip;
Tilanus, Marcel G. J.;
Koole, Ronald;
Hordijk, Gert-Jan;
van der Vliet, Peter C.;
Reinders, Marcel J. T.;
Slootweg, Piet J.;
Holstege, Frank C. P.

Publication type:

Article

Efficacy, safety and biomarker analysis of durvalumab in patients with mismatch-repair deficient or microsatellite instability-high solid tumours.

Published in:

BMC Cancer, 2023, v. 23, n. 1, p. 1, doi. 10.1186/s12885-023-10663-2

By:

Geurts, Birgit S.;
Battaglia, Thomas W.;
van Berge Henegouwen, J. Maxime;
Zeverijn, Laurien J.;
de Wit, Gijs F.;
Hoes, Louisa R.;
van der Wijngaart, Hanneke;
van der Noort, Vincent;
Roepman, Paul;
de Leng, Wendy W. J.;
Jansen, Anne M. L.;
Opdam, Frans L.;
de Jonge, Maja J. A.;
Cirkel, Geert A.;
Labots, Mariette;
Hoeben, Ann;
Kerver, Emile D.;
Bins, Adriaan D.;
Erdkamp, Frans G.L.;
van Rooijen, Johan M.

Publication type:

Article

RIP140 increases APC expression and controls intestinal homeostasis and tumorigenesis.

Published in:

2014

By:

Lapierre, Marion;
Bonnet, Sandrine;
Bascoul-Mollevi, Caroline;
Ait-Arsa, Imade;
Jalaguier, Stéphan;
Del Rio, Maguy;
Plateroti, Michela;
Roepman, Paul;
Ychou, Marc;
Pannequin, Julie;
Hollande, Frédéric;
Parker, Malcolm;
Cavailles, Vincent

Publication type:

journal article

RIP140 increases APC expression and controls intestinal homeostasis and tumorigenesis.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 5, p. 1899, doi. 10.1172/JCI65178

By:

Lapierre, Marion;
Bonnet, Sandrine;
Bascoul-Mollevi, Caroline;
Ait-Arsa, Imade;
Jalaguier, Stéphan;
Del Rio, Maguy;
Plateroti, Michela;
Roepman, Paul;
Ychou, Marc;
Pannequin, Julie;
Hollande, Frédéric;
Parker, Malcolm;
Cavailles, Vincent

Publication type:

Article

An international study comparing conventional versus mRNA level testing (TargetPrint) for ER, PR, and HER2 status of breast cancer.

Published in:

2016

By:

Wesseling, Jelle;
Tinterri, Corrado;
Sapino, Anna;
Zanconati, Fabrizio;
Lutke-Holzik, Martijn;
Nguyen, Bichlien;
Deck, Kenneth;
Querzoli, Patrizia;
Perin, Tiziana;
Giardina, Carmela;
Seitz, Gerhard;
Guinebretière, Jean-Marc;
Barone, Julie;
Dekker, Laura;
Snoo, Femke;
Stork-Sloots, Lisette;
Roepman, Paul;
Watanabe, Toru;
Cusumano, Pino;
Deck, Kenneth B

Publication type:

journal article

Biological Functions of the Genes in the Mammaprint Breast Cancer Profile Reflect the Hallmarks of Cancer.

Published in:

Biomarker Insights, 2010, n. 5, p. 129, doi. 10.4137/BMI.S6184

By:

Tian, Sun;
Roepman, Paul;
van't Veer, Laura J.;
Bernards, Rene;
de Snoo, Femke;
Glas, Annuska M.

Publication type:

Article

Optimized whole-genome sequencing workflow for tumor diagnostics in routine pathology practice.

Published in:

Nature Protocols, 2024, v. 19, n. 3, p. 700, doi. 10.1038/s41596-023-00933-5

By:

Samsom, Kris G.;
Bosch, Linda J. W.;
Schipper, Luuk J.;
Schout, Daoin;
Roepman, Paul;
Boelens, Mirjam C.;
Lalezari, Ferry;
Klompenhouwer, Elisabeth G.;
de Langen, Adrianus J.;
Buffart, Tineke E.;
van Linder, Berit M. H.;
van Deventer, Kelly;
van den Burg, Kay;
Unmehopa, Unga;
Rosenberg, Efraim H.;
Koster, Roelof;
Hogervorst, Frans B. L.;
van den Berg, José G.;
Riethorst, Immy;
Schoenmaker, Lieke

Publication type:

Article

A diagnostic gene profile for molecular subtyping of breast cancer associated with treatment response.

Published in:

Breast Cancer Research & Treatment, 2012, v. 133, n. 1, p. 37, doi. 10.1007/s10549-011-1683-z

By:

Krijgsman, Oscar;
Roepman, Paul;
Zwart, Wilbert;
Carroll, Jason;
Tian, Sun;
Snoo, Femke;
Bender, Richard;
Bernards, Rene;
Glas, Annuska

Publication type:

Article

Deoxycytidine kinase is overexpressed in poor outcome breast cancer and determines responsiveness to nucleoside analogs.

Published in:

Breast Cancer Research & Treatment, 2012, v. 131, n. 3, p. 809, doi. 10.1007/s10549-011-1477-3

By:

Geutjes, Ernst-Jan;
Tian, Sun;
Roepman, Paul;
Bernards, René

Publication type:

Article

Targeted Treatment Options of Recurrent Radioactive Iodine Refractory Hürthle Cell Cancer.

Published in:

Cancers, 2019, v. 11, n. 8, p. 1185, doi. 10.3390/cancers11081185

By:

Aydemirli, Mehtap Derya;
Corver, Willem;
Beuk, Ruben;
Roepman, Paul;
Solleveld-Westerink, Nienke;
van Wezel, Tom;
Kapiteijn, Ellen;
Morreau, Hans

Publication type:

Article

Tumor Profiling Turmoil.

Published in:

Cell Cycle, 2005, v. 4, n. 5, p. 659, doi. 10.4161/cc.4.5.1679

By:

Roepman, Paul;
Holstege, Frank C. P.

Publication type:

Article

Colorectal cancer intrinsic subtypes predict chemotherapy benefit, deficient mismatch repair and epithelial-to-mesenchymal transition.

Published in:

International Journal of Cancer, 2014, v. 134, n. 3, p. 552, doi. 10.1002/ijc.28387

By:

Roepman, Paul;
Schlicker, Andreas;
Tabernero, Josep;
Majewski, Ian;
Tian, Sun;
Moreno, Victor;
Snel, Mireille H;
Chresta, Christine M;
Rosenberg, Robert;
Nitsche, Ulrich;
Macarulla, Teresa;
Capella, Gabriel;
Salazar, Ramon;
Orphanides, George;
Wessels, Lodewyk FA;
Bernards, Rene;
Simon, Iris M

Publication type:

Article

Personalised selection of experimental treatment in patients with advanced solid cancer is feasible using whole-genome sequencing.

Published in:

2022

By:

Pruis, Melinda A.;
Groenendijk, Floris H.;
Badloe, K. Sangeeta;
van Puffelen, Andrea;
Robbrecht, Debbie;
Dinjens, Winand N. M.;
Sleijfer, Stefan;
Dingemans, Anne-Marie C.;
von der Thüsen, Jan H.;
Roepman, Paul;
Lolkema, Martijn P.

Publication type:

journal article

Integrated assessment by multiple gene expression analysis of quercetin bioactivity on anticancer-related mechanisms in colon cancer cells in vitro.

Published in:

European Journal of Nutrition, 2005, v. 44, n. 3, p. 143, doi. 10.1007/s00394-004-0503-1

By:

Erk, Marjan J.;
Roepman, Paul;
van der Lende, Ted R.;
Stierum, Rob H.;
Aarts, Jac M. M. J. G.;
van Bladeren, Peter J.;
van Ommen, Ben

Publication type:

Article

Clinical Impact of Prospective Whole Genome Sequencing in Sarcoma Patients.

Published in:

Cancers, 2022, v. 14, n. 2, p. 436, doi. 10.3390/cancers14020436

By:

Schipper, Luuk J.;
Monkhorst, Kim;
Samsom, Kris G.;
Bosch, Linda J.W.;
Snaebjornsson, Petur;
van Boven, Hester;
Roepman, Paul;
van der Kolk, Lizet E.;
van Houdt, Winan J.;
van der Graaf, Winette T.A.;
Meijer, Gerrit A.;
Voest, Emile E.

Publication type:

Article

A Truncated NRIP1 Mutant Amplifies Microsatellite Instability of Colorectal Cancer by Regulating MSH2/MSH6 Expression, and Is a Prognostic Marker of Stage III Tumors.

Published in:

Cancers, 2021, v. 13, n. 17, p. 4449, doi. 10.3390/cancers13174449

By:

Palassin, Pascale;
Lapierre, Marion;
Pyrdziak, Samuel;
Wagner, Antoine;
Stehle, Régine;
Corsini, Carole;
Duffour, Jacqueline;
Bonnet, Sandrine;
Boulahtouf, Abdelhay;
Rodriguez, Carmen;
Ho-Pun-Cheung, Alexandre;
Lopez-Crapez, Evelyne;
Boissière-Michot, Florence;
Bibeau, Frédéric;
Thezenas, Simon;
Elarouci, Nabila;
Selves, Janick;
Hoffmann, Jean-Sébastien;
Roepman, Paul;
Mazard, Thibault

Publication type:

Article

The consensus molecular subtypes of colorectal cancer.

Published in:

Nature Medicine, 2015, v. 21, n. 11, p. 1350, doi. 10.1038/nm.3967

By:

Guinney, Justin;
Dienstmann, Rodrigo;
Wang, Xin;
de Reyniès, Aurélien;
Schlicker, Andreas;
Soneson, Charlotte;
Marisa, Laetitia;
Roepman, Paul;
Nyamundanda, Gift;
Angelino, Paolo;
Bot, Brian M;
Morris, Jeffrey S;
Simon, Iris M;
Gerster, Sarah;
Fessler, Evelyn;
De Sousa E Melo, Felipe;
Missiaglia, Edoardo;
Ramay, Hena;
Barras, David;
Homicsko, Krisztian

Publication type:

Article

Soft tissue angiofibroma: Clinicopathologic, immunohistochemical and molecular analysis of 14 cases.

Published in:

Genes, Chromosomes & Cancer, 2017, v. 56, n. 10, p. 750, doi. 10.1002/gcc.22478

By:

Bekers, Elise M;
Groenen, Patricia JTA;
Verdijk, Marian AJ;
Raaijmakers‐van Geloof, Winny L;
Roepman, Paul;
Vink, Robert;
Gilhuijs, Nathalie DB;
van Gorp, Joost M;
Bovée, Judith VMG;
Creytens, David H;
Flanagan, Adrienne M;
Suurmeijer, Albert JH;
Mentzel, Thomas;
Arbajian, Elsa;
Flucke, Uta

Publication type:

Article

Driver mutations occur frequently in metastases of well‐differentiated small intestine neuroendocrine tumours.

Published in:

Histopathology, 2021, v. 78, n. 4, p. 556, doi. 10.1111/his.14252

By:

Samsom, Kris G;
Levy, Sonja;
Veenendaal, Linde M;
Roepman, Paul;
Kodach, Liudmila L;
Steeghs, Neeltje;
Valk, Gerlof D;
Wouter Dercksen, M;
Kuhlmann, Koert F D;
Verbeek, Wieke H M;
Meijer, Gerrit A;
Tesselaar, Margot E T;
Berg, José G

Publication type:

Article

Early Cost Effectiveness of Whole-Genome Sequencing as a Clinical Diagnostic Test for Patients with Inoperable Stage IIIB,C/IV Non-squamous Non-small-Cell Lung Cancer.

Published in:

PharmacoEconomics, 2021, v. 39, n. 12, p. 1429, doi. 10.1007/s40273-021-01073-y

By:

Simons, Martijn J. H. G.;
Retèl, Valesca P.;
Ramaekers, Bram L. T.;
Butter, Rogier;
Mankor, Joanne M.;
Paats, Marthe S.;
Aerts, Joachim G. J. V.;
Mfumbilwa, Zakile A.;
Roepman, Paul;
Coupé, Veerle M. H.;
Uyl-de Groot, Carin A.;
van Harten, Wim H.;
Joore, Manuela A.

Publication type:

Article

Limited clinical activity of palbociclib and ribociclib monotherapy in advanced cancers with cyclin D‐CDK4/6 pathway alterations in the Dutch DRUP and Australian MoST trials.

Published in:

International Journal of Cancer, 2023, v. 153, n. 7, p. 1413, doi. 10.1002/ijc.34649

By:

Zeverijn, Laurien J.;
Looze, Eleonora J.;
Thavaneswaran, Subotheni;
van Berge Henegouwen, J. Maxime;
Simes, Robert J.;
Hoes, Louisa R.;
Sjoquist, Katrin M.;
van der Wijngaart, Hanneke;
Sebastian, Lucille;
Geurts, Birgit S.;
Lee, Chee K.;
de Wit, Gijsbrecht F.;
Espinoza, David;
Roepman, Paul;
Lin, Frank P.;
Jansen, Anne M. L.;
de Leng, Wendy W. J.;
van der Noort, Vincent;
Leek, Lindsay V. M.;
de Vos, Filip Y. F. L.

Publication type:

Article

A Prognostic Gene Expression Profile That Predicts Circulating Tumor Cell Presence in Breast Cancer Patients.

Published in:

PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0032426

By:

Molloy, Timothy J.;
Roepman, Paul;
Naume, Bjørn;
Veer, Laura J. van't

Publication type:

Article

Integration of Gene Dosage and Gene Expression in Non-Small Cell Lung Cancer, Identification of HSP90 as Potential Target.

Published in:

PLoS ONE, 2008, v. 3, n. 3, p. 1, doi. 10.1371/journal.pone.0001722

By:

Ruiz, Mariälle I. Gallegos;
Floor, Karijn;
Roepman, Paul;
Rodriguez, José A.;
Meijer, Gerrit A.;
Mooi, Wolter J.;
Jassem, Ewa;
Niklinski, Jacek;
Muley, Thomas;
van Zandwijk, Nico;
Smit, Egbert F.;
Beebe, Kristin;
Neckers, Len;
Ylstra, Bauke;
Giaccone, Giuseppe

Publication type:

Article

Characterization of discordance between mismatch repair deficiency and microsatellite instability testing may prevent inappropriate treatment with immunotherapy.

Published in:

Journal of Pathology, 2024, v. 263, n. 3, p. 288, doi. 10.1002/path.6279

By:

Geurts, Birgit S;
Zeverijn, Laurien J;
van Berge Henegouwen, Jade M;
van der Wijngaart, Hanneke;
Hoes, Louisa R;
de Wit, Gijs F;
Spiekman, Ilse AC;
Battaglia, Thomas W;
van Beek, Daphne M;
Roepman, Paul;
Jansen, Anne ML;
de Leng, Wendy WJ;
Broeks, Annegien;
Labots, Mariette;
van Herpen, Carla ML;
Gelderblom, Hans;
Verheul, Henk MW;
Snaebjornsson, Petur;
Voest, Emile E

Publication type:

Article

Feasibility of whole‐genome sequencing‐based tumor diagnostics in routine pathology practice.

Published in:

Journal of Pathology, 2022, v. 258, n. 2, p. 179, doi. 10.1002/path.5988

By:

Samsom, Kris G;
Schipper, Luuk J;
Roepman, Paul;
Bosch, Linda JW;
Lalezari, Ferry;
Klompenhouwer, Elisabeth G;
de Langen, Adrianus J;
Buffart, Tineke E;
Riethorst, Immy;
Schoenmaker, Lieke;
Schout, Daoin;
van der Noort, Vincent;
van den Berg, Jose G;
de Bruijn, Ewart;
van der Hoeven, Jacobus JM;
van Snellenberg, Hans;
van der Kolk, Lizet E;
Cuppen, Edwin;
Voest, Emile E;
Meijer, Gerrit A

Publication type:

Article

Identification of recurrent FGFR3 fusion genes in lung cancer through kinome-centred RNA sequencing.

Published in:

Journal of Pathology, 2013, v. 230, n. 3, p. 270, doi. 10.1002/path.4209

By:

Majewski, Ian J;
Mittempergher, Lorenza;
Davidson, Nadia M;
Bosma, Astrid;
Willems, Stefan M;
Horlings, Hugo M;
de Rink, Iris;
Greger, Liliana;
Hooijer, Gerrit KJ;
Peters, Dennis;
Nederlof, Petra M;
Hofland, Ingrid;
de Jong, Jeroen;
Wesseling, Jelle;
Kluin, Roelof JC;
Brugman, Wim;
Kerkhoven, Ron;
Nieboer, Frank;
Roepman, Paul;
Broeks, Annegien

Publication type:

Article

A robust genomic signature for the detection of colorectal cancer patients with microsatellite instability phenotype and high mutation frequency.

Published in:

Journal of Pathology, 2012, v. 228, n. 4, p. 586, doi. 10.1002/path.4092

By:

Tian, Sun;
Roepman, Paul;
Popovici, Vlad;
Michaut, Magali;
Majewski, Ian;
Salazar, Ramon;
Santos, Cristina;
Rosenberg, Robert;
Nitsche, Ulrich;
Mesker, Wilma E;
Bruin, Sjoerd;
Tejpar, Sabine;
Delorenzi, Mauro;
Bernards, Rene;
Simon, Iris

Publication type:

Article