Works by Roep, Bart O


Results: 119
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    A randomised, single-blind, placebo-controlled, dose-finding safety and tolerability study of the anti-CD3 monoclonal antibody otelixizumab in new-onset type 1 diabetes.

    Published in:
    Diabetologia, 2021, v. 64, n. 2, p. 313, doi. 10.1007/s00125-020-05317-y
    By:
    • Keymeulen, Bart;
    • van Maurik, André;
    • Inman, Dave;
    • Oliveira, João;
    • McLaughlin, Rene;
    • Gittelman, Rachel M.;
    • Roep, Bart O.;
    • Gillard, Pieter;
    • Hilbrands, Robert;
    • Gorus, Frans;
    • Mathieu, Chantal;
    • Van de Velde, Ursule;
    • Wisniacki, Nicolas;
    • Napolitano, Antonella
    Publication type:
    Article
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    Studies of insulin and proinsulin in pancreas and serum support the existence of aetiopathological endotypes of type 1 diabetes associated with age at diagnosis.

    Published in:
    Diabetologia, 2020, v. 63, n. 6, p. 1258, doi. 10.1007/s00125-020-05115-6
    By:
    • Leete, Pia;
    • Oram, Richard A.;
    • McDonald, Timothy J.;
    • Shields, Beverley M.;
    • Ziller, Clemens;
    • TIGI study team;
    • Roep, Bart O.;
    • Tree, Timothy I.;
    • Patel, Kashyap;
    • Hammersley, Suzy;
    • Bolt, Robert;
    • Hill, Anita V.;
    • Hattersley, Andrew T.;
    • Richardson, Sarah J.;
    • Morgan, Noel G.
    Publication type:
    Article
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    Abnormal islet sphingolipid metabolism in type 1 diabetes.

    Published in:
    Diabetologia, 2018, v. 61, n. 7, p. 1650, doi. 10.1007/s00125-018-4614-2
    By:
    • Holm, Laurits J.;
    • Krogvold, Lars;
    • Hasselby, Jane P.;
    • Kaur, Simranjeet;
    • Claessens, Laura A.;
    • Russell, Mark A.;
    • Mathews, Clayton E.;
    • Hanssen, Kristian F.;
    • Morgan, Noel G.;
    • Koeleman, Bobby P. C.;
    • Roep, Bart O.;
    • Gerling, Ivan C.;
    • Pociot, Flemming;
    • Dahl-Jørgensen, Knut;
    • Buschard, Karsten
    Publication type:
    Article
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    Proteasomal Degradation of Proinsulin Requires Derlin-2, HRD1 and p97.

    Published in:
    PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0128206
    By:
    • Hoelen, Hanneke;
    • Zaldumbide, Arnaud;
    • van Leeuwen, Wouter F.;
    • Torfs, Ellen C. W.;
    • Engelse, Marten A.;
    • Hassan, Chopie;
    • Lebbink, Robert Jan;
    • de Koning, Eelco J.;
    • Resssing, Maaike E.;
    • de Ru, Arnoud H.;
    • van Veelen, Peter A.;
    • Hoeben, Rob C.;
    • Roep, Bart O.;
    • Wiertz, Emmanuel J. H. J.
    Publication type:
    Article
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    Islet-Specific CTL Cloned from a Type 1 Diabetes Patient Cause Beta-Cell Destruction after Engraftment into HLA-A2 Transgenic NOD/SCID/IL2RG Null Mice.

    Published in:
    PLoS ONE, 2012, v. 7, n. 11, p. 1, doi. 10.1371/journal.pone.0049213
    By:
    • Unger, Wendy W. J.;
    • Pearson, Todd;
    • Abreu, Joana R. F.;
    • Laban, Sandra;
    • van der Slik, Arno R.;
    • Mulder-van der Kracht, Sacha;
    • Kester, Michel G. D.;
    • Serreze, Dave V.;
    • Shultz, Leonard D.;
    • Griffioen, Marieke;
    • Drijfhout, Jan Wouter;
    • Greiner, Dale L.;
    • Roep, Bart O.
    Publication type:
    Article
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    Cellular Islet Autoimmunity Associates with Clinical Outcome of Islet Cell Transplantation.

    Published in:
    PLoS ONE, 2008, v. 3, n. 6, p. 1, doi. 10.1371/journal.pone.0002435
    By:
    • Huurman, Volkert A. L.;
    • Hilbrands, Robert;
    • Pinkse, Gabriëlle G. M.;
    • Gillard, Pieter;
    • Duinkerken, Gaby;
    • van de Linde, Pieter;
    • van der Meer-Prins, Petronella M. W.;
    • Maarschalk, Minke F. J. Versteeg-van der Voort;
    • Verbeeck, Koen;
    • Alizadeh, Behrooz Z.;
    • Mathieu, Chantal;
    • Gorus, Frans K.;
    • Roelen, Dave L.;
    • Claas, Frans H. J.;
    • Keymeulen, Bart;
    • Pipeleers, Daniel G.;
    • Roep, Bart O.
    Publication type:
    Article
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    KIR in Type 1 Diabetes.

    Published in:
    Diabetes, 2003, v. 52, n. 10, p. 2639, doi. 10.2337/diabetes.52.10.2639
    By:
    • van der Slik, Arno R.;
    • Koeleman, Bobby P.C.;
    • Verduijn, Willem;
    • Bruining, G. Jan;
    • Roep, Bart O.;
    • Giphart, Marius J.
    Publication type:
    Article
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    Characterization of preparations of GAD65, proinsulin, and the islet tyrosine phosphatase IA-2 for use in detection of autoreactive T-cells in type 1 diabetes: report of phase II of the Second International Immunology of Diabetes Society Workshop for Standardization of T-cell assays in type 1 diabetes.

    Published in:
    2001
    By:
    • Peakman, Mark;
    • Tree, Timothy I.;
    • Endl, Josef;
    • Van Endert, Peter;
    • Atkinson, Mark A.;
    • Roep, Bart O.;
    • Peakman, M;
    • Tree, T I;
    • Endl, J;
    • van Endert, P;
    • Atkinson, M A;
    • Roep, B O;
    • Second International Immunology of Diabetes Society Workshop for Standardization ot T-cell Assays in Type 1 Diabetes
    Publication type:
    journal article
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    TNFa microsatellite polymorphism modulates the risk of IDDM in Caucasians with the high-risk genotype HLA DQA1*0501-DQB1*0201/DQA1*0301-DQB1*0302. Belgian Diabetes Registry.

    Published in:
    1997
    By:
    • Moghaddam, Payman Hanifi;
    • Zwinderman, Aeilko H.;
    • de Knijff, Peter;
    • Roep, Bart O.;
    • Schipper, Ron F.;
    • Van Der Auwera, Bart;
    • Naipal, Albert;
    • Gorus, Frans;
    • Schuit, Frans;
    • Giphart, Marius J.;
    • Moghaddam, P H;
    • Zwinderman, A H;
    • de Knijff, P;
    • Roep, B O;
    • Schipper, R F;
    • Van der Auwera, B;
    • Naipal, A;
    • Gorus, F;
    • Schuit, F;
    • Giphart, M J
    Publication type:
    journal article
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    Challenges in developing endpoints for type 1 diabetes intervention studies.

    Published in:
    Diabetes/Metabolism Research & Reviews, 2009, v. 25, n. 8, p. 694, doi. 10.1002/dmrr.1002
    By:
    • Cernea, Simona;
    • Raz, Itamar;
    • Herold, Kevan C.;
    • Hirshberg, Boaz;
    • Roep, Bart O.;
    • Schatz, Desmond A.;
    • Fleming, G. Alexander;
    • Pozzilli, Paolo;
    • Little, Randie;
    • Schloot, Nanette C.;
    • Leslie, R. David G.;
    • Skyler, Jay S.;
    • Palmer, Jerry P.
    Publication type:
    Article
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