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Anti‐TNF treatment negatively regulates human CD4+ T‐cell activation and maturation in vitro, but does not confer an anergic or suppressive phenotype.
Published in:
European Journal of Immunology, 2020, v. 50, n. 3, p. 445, doi. 10.1002/eji.201948190
By:
- Povoleri, Giovanni A. M.;
- Lalnunhlimi, Sylvine;
- Steel, Kathryn J. A.;
- Agrawal, Shweta;
- O'Byrne, Aoife M.;
- Ridley, Michael;
- Kordasti, Shahram;
- Frederiksen, Klaus S.;
- Roberts, Ceri A.;
- Taams, Leonie S.
Publication type:
Article
Conserved human effector Treg cell transcriptomic and epigenetic signature in arthritic joint inflammation.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-22975-7
By:
- Mijnheer, Gerdien;
- Lutter, Lisanne;
- Mokry, Michal;
- van der Wal, Marlot;
- Scholman, Rianne;
- Fleskens, Veerle;
- Pandit, Aridaman;
- Tao, Weiyang;
- Wekking, Mark;
- Vervoort, Stephin;
- Roberts, Ceri;
- Petrelli, Alessandra;
- Peeters, Janneke G. C.;
- Knijff, Marthe;
- de Roock, Sytze;
- Vastert, Sebastiaan;
- Taams, Leonie S.;
- van Loosdregt, Jorg;
- van Wijk, Femke
Publication type:
Article
The cholesterol biosynthesis pathway regulates IL-10 expression in human Th1 cells.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-08332-9
By:
- Perucha, Esperanza;
- Melchiotti, Rossella;
- Bibby, Jack A;
- Wu, Wing;
- Frederiksen, Klaus Stensgaard;
- Roberts, Ceri A.;
- Hall, Zoe;
- LeFriec, Gaelle;
- Robertson, Kevin A.;
- Lavender, Paul;
- Gerwien, Jens Gammeltoft;
- Taams, Leonie S.;
- Griffin, Julian L.;
- de Rinaldis, Emanuele;
- van Baarsen, Lisa G. M.;
- Kemper, Claudia;
- Ghazal, Peter;
- Cope, Andrew P.
Publication type:
Article
TNF-α blockade induces IL-10 expression in human CD4+ T cells.
Published in:
Nature Communications, 2014, v. 5, n. 2, p. 3199, doi. 10.1038/ncomms4199
By:
- Evans, Hayley G.;
- Roostalu, Urmas;
- Walter, Gina J.;
- Gullick, Nicola J.;
- Frederiksen, Klaus S.;
- Roberts, Ceri A.;
- Sumner, Jonathan;
- Baeten, Dominique L.;
- Gerwien, Jens G.;
- Cope, Andrew P.;
- Geissmann, Frederic;
- Kirkham, Bruce W.;
- Taams, Leonie S.
Publication type:
Article
TNF Blockade Maintains an IL-10+ Phenotype in Human Effector CD4+ and CD8+ T Cells.
Published in:
Frontiers in Immunology, 2017, v. 8, p. 1, doi. 10.3389/fimmu.2017.00157
By:
- Roberts, Ceri A.;
- Durham, Lucy E.;
- Fleskens, Veerle;
- Evans, Hayley G.;
- Taams, Leonie S.
Publication type:
Article
The Interplay Between Monocytes/Macrophages and CD4+ T Cell Subsets in Rheumatoid Arthritis.
Published in:
Frontiers in Immunology, 2015, v. 6, p. 1, doi. 10.3389/fimmu.2015.00571
By:
- Roberts, Ceri A.;
- Dickinson, Abigail K.;
- Taams, Leonie S.;
- Garside, Paul;
- Ginhoux, Florent
Publication type:
Article

Found: 6

Anti‐TNF treatment negatively regulates human CD4<sup>+</sup> T‐cell activation and maturation in vitro, but does not confer an anergic or suppressive phenotype.

Conserved human effector Treg cell transcriptomic and epigenetic signature in arthritic joint inflammation.

The cholesterol biosynthesis pathway regulates IL-10 expression in human Th1 cells.

TNF-α blockade induces IL-10 expression in human CD4+ T cells.

TNF Blockade Maintains an IL-10<sup>+</sup> Phenotype in Human Effector CD4<sup>+</sup> and CD8<sup>+</sup> T Cells.

The Interplay Between Monocytes/Macrophages and CD4<sup>+</sup> T Cell Subsets in Rheumatoid Arthritis.