Works by Roberto Perrone

Results: 31

Guinea-pig ileum as ex vivo model useful to characterize ligands displaying Imidazoline I2 and Adrenergic alpha2 mixed activity: a preliminary study.

Published in:

Drugs & Therapy Studies, 2013, v. 3, n. 1, p. 1, doi. 10.4081/dts.2013.e1

By:

Contino, Marialessandra;
Carrieri, Antonio;
Berardi, Francesco;
Leopoldo, Marcello;
Perrone, Roberto;
Thomas, Russell;
Colabufo, Nicola Antonio

Publication type:

Article

Deciphering the Supramolecular Organization of Multiple Guests Inside a Microporous MOF to Understand their Release Profile.

Published in:

Angewandte Chemie, 2021, v. 133, n. 18, p. 10282, doi. 10.1002/ange.202017105

By:

Balestri, Davide;
Mazzeo, Paolo P.;
Perrone, Roberto;
Fornari, Fabio;
Bianchi, Federica;
Careri, Maria;
Bacchi, Alessia;
Pelagatti, Paolo

Publication type:

Article

Towards metabolically stable 5-HT receptor ligands: a study on 1-arylpiperazine derivatives and related isosters.

Published in:

Experimental Brain Research, 2013, v. 230, n. 4, p. 569, doi. 10.1007/s00221-013-3498-0

By:

Lacivita, Enza;
De Giorgio, Paola;
Patarnello, Daniela;
Niso, Mauro;
Colabufo, Nicola;
Berardi, Francesco;
Perrone, Roberto;
Satala, Grzegorz;
Duszynska, Beata;
Bojarski, Andrzej;
Leopoldo, Marcello

Publication type:

Article

Tyrosine kinase inhibitors and multidrug resistance proteins: interactions and biological consequences.

Published in:

Cancer Chemotherapy & Pharmacology, 2010, v. 65, n. 2, p. 335, doi. 10.1007/s00280-009-1039-0

By:

Azzariti, Amalia;
Porcelli, Letizia;
Simone, Grazia M.;
Quatrale, Anna E.;
Colabufo, Nicola A.;
Berardi, Francesco;
Perrone, Roberto;
Zucchetti, Massimo;
D'Incalci, Maurizio;
Jian Ming Xu;
Paradiso, Angelo

Publication type:

Article

Antiproliferative and cytotoxic effects of some σ2 agonists and σ1 antagonists in tumour cell lines.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2004, v. 370, n. 2, p. 106

By:

Colabufo, Nicola Antonio;
Berardi, Francesco;
Contino, Marialessandra;
Niso, Mauro;
Abate, Carmen;
Perrone, Roberto;
Tortorella, Vincenzo

Publication type:

Article

A new method for evaluating σ2 ligand activity in the isolated guinea-pig bladder.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2003, v. 368, n. 2, p. 106, doi. 10.1007/s00210-003-0777-5

By:

Colabufo, Nicola A.;
Berardi, Francesco;
Contino, Marialessandra;
Perrone, Roberto;
Tortorella, Vincenzo

Publication type:

Article

Deciphering the Supramolecular Organization of Multiple Guests Inside a Microporous MOF to Understand their Release Profile.

Published in:

Angewandte Chemie International Edition, 2021, v. 60, n. 18, p. 10194, doi. 10.1002/anie.202017105

By:

Balestri, Davide;
Mazzeo, Paolo P.;
Perrone, Roberto;
Fornari, Fabio;
Bianchi, Federica;
Careri, Maria;
Bacchi, Alessia;
Pelagatti, Paolo

Publication type:

Article

Small-animal PET evaluation of [11C]MC113 as a PET tracer for P-glycoprotein.

Published in:

2010

By:

Mairinger, Severin;
Colabufo, Nicola A.;
Wanek, Thomas;
Kuntner, Claudia;
Stanek, Johann;
Erker, Thomas;
Cantore, Mariangela;
Berardi, Francesco;
Perrone, Roberto;
Müller, Markus;
Langer, Oliver

Publication type:

Abstract

Chemical Studies on Drug Metabolism: Oxidation with Ruthenium Tetroxide of Some Medicinal Alicyclic N-Methylamines.

Published in:

Archiv der Pharmazie, 1984, v. 317, n. 1, p. 21, doi. 10.1002/ardp.19843170106

By:

Perrone, Roberto;
Carbonara, Giuseppe;
Tortorella, Vincenzo

Publication type:

Article

Synthesis and Absolute Configurations of Hexahydro-Naphthoxazines as Rigid Congeners of Phenmetrazine.

Published in:

Archiv der Pharmazie, 1983, v. 316, n. 7, p. 617, doi. 10.1002/ardp.19833160707

By:

Perrone, Roberto;
Bettoni, Giancarlo;
Tortorella, Vincenzo

Publication type:

Article

Functional N-Formyl Peptide Receptor 2 (FPR2) Antagonists Based on the Ureidopropanamide Scaffold Have Potential To Protect Against Inflammation-Associated Oxidative Stress.

Published in:

ChemMedChem, 2017, v. 12, n. 22, p. 1839, doi. 10.1002/cmdc.201700429

By:

Stama, Madia L.;
Lacivita, Enza;
Kirpotina, Liliya N.;
Niso, Mauro;
Perrone, Roberto;
Schepetkin, Igor A.;
Quinn, Mark T.;
Leopoldo, Marcello

Publication type:

Article

PET Radiotracers for Imaging P-glycoprotein: The Challenge for Early Diagnosis in AD.

Published in:

ChemMedChem, 2014, v. 9, n. 1, p. 38, doi. 10.1002/cmdc.201300362

By:

Leopoldo, Marcello;
Contino, Marialessandra;
Berardi, Francesco;
Perrone, Roberto;
Colabufo, Nicola Antonio

Publication type:

Article

Inside Cover: Sigma-2 Receptor Agonists as Possible Antitumor Agents in Resistant Tumors: Hints for Collateral Sensitivity (ChemMedChem 12/2013).

Published in:

ChemMedChem, 2013, v. 8, n. 12, p. 1898, doi. 10.1002/cmdc.201390051

By:

Niso, Mauro;
Abate, Carmen;
Contino, Marialessandra;
Ferorelli, Savina;
Azzariti, Amalia;
Perrone, Roberto;
Colabufo, Nicola Antonio;
Berardi, Francesco

Publication type:

Article

Sigma-2 Receptor Agonists as Possible Antitumor Agents in Resistant Tumors: Hints for Collateral Sensitivity.

Published in:

ChemMedChem, 2013, v. 8, n. 12, p. 2026, doi. 10.1002/cmdc.201300291

By:

Niso, Mauro;
Abate, Carmen;
Contino, Marialessandra;
Ferorelli, Savina;
Azzariti, Amalia;
Perrone, Roberto;
Colabufo, Nicola Antonio;
Berardi, Francesco

Publication type:

Article

2-Aminopyridine Derivatives as Potential σ2 Receptor Antagonists.

Published in:

ChemMedChem, 2012, v. 7, n. 10, p. 1847, doi. 10.1002/cmdc.201200246

By:

Abate, Carmen;
Ferorelli, Savina;
Niso, Mauro;
Lovicario, Cesarea;
Infantino, Vittoria;
Convertini, Paolo;
Perrone, Roberto;
Berardi, Francesco

Publication type:

Article

A Benzopyrane Derivative as a P-Glycoprotein Stimulator: A Potential Agent to Decrease β-Amyloid Accumulation in Alzheimer's Disease.

Published in:

ChemMedChem, 2012, v. 7, n. 3, p. 391, doi. 10.1002/cmdc.201100469

By:

Contino, Marialessandra;
Cantore, Mariangela;
Capparelli, Elena;
Perrone, Maria Grazia;
Niso, Mauro;
Inglese, Carmela;
Berardi, Francesco;
Leopoldo, Marcello;
Perrone, Roberto;
Colabufo, Nicola Antonio

Publication type:

Article

Inside Cover: 1-Cyclohexyl-4-(4-arylcyclohexyl)piperazines: Mixed σ and Human Δ8-Δ7 Sterol Isomerase Ligands with Antiproliferative and P-Glycoprotein Inhibitory Activity (ChemMedChem 1/2011).

Published in:

ChemMedChem, 2011, v. 6, n. 1, p. 2, doi. 10.1002/cmdc.201090062

By:

Abate, Carmen;
Niso, Mauro;
Contino, Marialessandra;
Colabufo, Nicola Antonio;
Ferorelli, Savina;
Perrone, Roberto;
Berardi, Francesco

Publication type:

Article

1-Cyclohexyl-4-(4-arylcyclohexyl)piperazines: Mixed σ and Human Δ8-Δ7 Sterol Isomerase Ligands with Antiproliferative and P-Glycoprotein Inhibitory Activity.

Published in:

ChemMedChem, 2011, v. 6, n. 1, p. 73, doi. 10.1002/cmdc.201000371

By:

Abate, Carmen;
Niso, Mauro;
Contino, Marialessandra;
Colabufo, Nicola Antonio;
Ferorelli, Savina;
Perrone, Roberto;
Berardi, Francesco

Publication type:

Article

Multi-Drug-Resistance-Reverting Agents: 2-Aryloxazole and 2-Arylthiazole Derivatives as Potent BCRP or MRP1 Inhibitors.

Published in:

ChemMedChem, 2009, v. 4, n. 2, p. 188, doi. 10.1002/cmdc.200800329

By:

Colabufo, Nicola A.;
Berardi, Francesco;
Perrone, Maria Grazia;
Cantore, Mariangela;
Contino, Marialessandra;
Inglese, Carmela;
Niso, Mauro;
Perrone, Roberto

Publication type:

Article

Impact of Partitioning Temperature Parameters during the Quenching and Partitioning Process on Medium Carbon Steels with Two Different Alloying Strategies.

Published in:

Steel Research International, 2025, v. 96, n. 6, p. 1, doi. 10.1002/srin.202400710

By:

Franceschi, Mattia;
Stornelli, Giulia;
Perrone, Roberto;
Pezzato, Luca;
Di Schino, Andrea;
Dabalà, Manuele

Publication type:

Article

Chiroptical properties of cyclic amines.

Published in:

Journal of Heterocyclic Chemistry, 1979, v. 16, n. 3, p. 591, doi. 10.1002/jhet.5570160337

By:

Bettoni, Giancarlo;
Morlacchi, Flaviano;
Perrone, Roberto;
Tortorella, Vicenzo;
Vetuschi, Claudio

Publication type:

Article

Selective agonists for serotonin 7 (5-HT7) receptor and their applications in preclinical models: an overview.

Published in:

Reviews in the Neurosciences, 2014, v. 25, n. 3, p. 401, doi. 10.1515/revneuro-2014-0009

By:

Di Pilato, Pantaleo;
Niso, Mauro;
Adriani, Walter;
Romano, Emilia;
Travaglini, Domenica;
Berardi, Francesco;
Colabufo, Nicola A.;
Perrone, Roberto;
Laviola, Giovanni;
Lacivita, Enza;
Leopoldo, Marcello

Publication type:

Article

Functionalized Coumarine Fragment to Obtain Fluorescent and Selective P-Glycoprotein Ligands.

Published in:

Archiv der Pharmazie, 2016, v. 349, n. 3, p. 161, doi. 10.1002/ardp.201500325

By:

Capparelli, Elena;
Contino, Marialessandra;
Perrone, Maria G.;
Berardi, Francesco;
Perrone, Roberto;
Leopoldo, Marcello;
Colabufo, Nicola A.

Publication type:

Article

Synthesis and binding profile of constrained analogues of N-[4-(4-arylpiperazin-1-yl)butyl]-3-methoxybenzamides, a class of potent dopamine D3 receptor ligands.

Published in:

Journal of Pharmacy & Pharmacology, 2006, v. 58, n. 2, p. 209

By:

Marcello Leopoldo;
Enza Lacivita;
Nicola A. Colabufo;
Francesco Berardi;
Roberto Perrone

Publication type:

Article

Distribution of sigma receptors in EMT-6 cells: preliminary biological evaluation of PB167 and potential for in-vivo PET.

Published in:

Journal of Pharmacy & Pharmacology, 2005, v. 57, n. 11, p. 1453

By:

Nicola Antonio Colabufo;
Francesco Berardi;
Marialessandra Contino;
Ferruccio Fazio;
Mario Matarrese;
Rosa Maria Moresco;
Mauro Niso;
Roberto Perrone;
Vincenzo Tortorella

Publication type:

Article

Design and synthesis of long-chain arylpiperazines with mixed affinity for serotonin transporter (SERT) and 5-HT1A receptor.

Published in:

Journal of Pharmacy & Pharmacology, 2005, v. 57, n. 10, p. 1319

By:

Roberto Perrone;
Francesco Berardi;
Nicola A. Colabufo;
Enza Lacivita;
Carmela Larizza;
Marcello Leopoldo;
Vincenzo Tortorella

Publication type:

Article

Studies on 1-arylpiperazine derivatives with affinity for rat 5-HT7 and 5-HT1A receptors.

Published in:

Journal of Pharmacy & Pharmacology, 2004, v. 56, n. 2, p. 247

By:

Marcello Leopoldo;
Francesco Berardi;
Nicola A. Colabufo;
Marialessandra Contino;
Enza Lacivita;
Roberto Perrone;
Vincenzo Tortorella

Publication type:

Article

Radiosynthesis and in vivo Evaluation of Carbon-11 (2 S)-3-(1 H-Indol-3-yl)-2-{[(4-methoxyphenyl)carbamoyl]amino}- N-{[1-(5-methoxypyridin-2-yl)cyclohexyl]methyl}propanamide: An Attempt to Visualize Brain Formyl Peptide Receptors in Mouse Models of Neuroinflammation

Published in:

Chemistry & Biodiversity, 2016, v. 13, n. 7, p. 875, doi. 10.1002/cbdv.201500281

By:

Lacivita, Enza;
Stama, Madia Letizia;
Maeda, Jun;
Fujinaga, Masayuki;
Hatori, Akiko;
Zhang, Ming‐Rong;
Colabufo, Nicola A.;
Perrone, Roberto;
Higuchi, Makoto;
Suhara, Tetsuya;
Leopoldo, Marcello

Publication type:

Article

Design, Synthesis, Lipophilic Properties, and Binding Affinities of Potential Ligands in Positron Emission Tomography (PET) for Visualization of Brain Dopamine D4 Receptors.

Published in:

Chemistry & Biodiversity, 2014, v. 11, n. 2, p. 299, doi. 10.1002/cbdv.201300194

By:

Lacivita, Enza;
De Giorgio, Paola;
Colabufo, Nicola A.;
Berardi, Francesco;
Perrone, Roberto;
Niso, Mauro;
Leopoldo, Marcello

Publication type:

Article

Same Behaviour in Obtaining Azirines from 1-Tetralones and a 7-Oxo-tetrahydrobenzothiazole.

Published in:

Archiv der Pharmazie, 1991, v. 324, n. 5, p. 297, doi. 10.1002/ardp.19913240508

By:

Perrone, Roberto;
Berardi, Francesco;
Tortorella, Vincenzo

Publication type:

Article

Chemical Studies on Drug Metabolism II. N-Demethylation and N-Oxidation of Some Alicyclic Amines by Ruthenium Tetroxide.

Published in:

Archiv der Pharmazie, 1984, v. 317, n. 7, p. 635, doi. 10.1002/ardp.19843170712

By:

Perrone, Roberto;
Carbonara, Giuseppe;
Tortorella, Vincenzo

Publication type:

Article

Works by Roberto Perrone

Guinea-pig ileum as ex vivo model useful to characterize ligands displaying Imidazoline I<sub>2</sub> and Adrenergic alpha<sub>2</sub> mixed activity: a preliminary study.

Deciphering the Supramolecular Organization of Multiple Guests Inside a Microporous MOF to Understand their Release Profile.

Towards metabolically stable 5-HT receptor ligands: a study on 1-arylpiperazine derivatives and related isosters.

Tyrosine kinase inhibitors and multidrug resistance proteins: interactions and biological consequences.

Antiproliferative and cytotoxic effects of some σ<sub>2</sub> agonists and σ<sub>1</sub> antagonists in tumour cell lines.

A new method for evaluating σ<sub>2</sub> ligand activity in the isolated guinea-pig bladder.

Deciphering the Supramolecular Organization of Multiple Guests Inside a Microporous MOF to Understand their Release Profile.

Small-animal PET evaluation of [<sup>11</sup>C]MC113 as a PET tracer for P-glycoprotein.

Chemical Studies on Drug Metabolism: Oxidation with Ruthenium Tetroxide of Some Medicinal Alicyclic N-Methylamines.

Synthesis and Absolute Configurations of Hexahydro-Naphthoxazines as Rigid Congeners of Phenmetrazine.

Functional N-Formyl Peptide Receptor 2 (FPR2) Antagonists Based on the Ureidopropanamide Scaffold Have Potential To Protect Against Inflammation-Associated Oxidative Stress.

PET Radiotracers for Imaging P-glycoprotein: The Challenge for Early Diagnosis in AD.

Inside Cover: Sigma-2 Receptor Agonists as Possible Antitumor Agents in Resistant Tumors: Hints for Collateral Sensitivity (ChemMedChem 12/2013).

Sigma-2 Receptor Agonists as Possible Antitumor Agents in Resistant Tumors: Hints for Collateral Sensitivity.

2-Aminopyridine Derivatives as Potential σ<sub>2</sub> Receptor Antagonists.

A Benzopyrane Derivative as a P-Glycoprotein Stimulator: A Potential Agent to Decrease β-Amyloid Accumulation in Alzheimer's Disease.

Inside Cover: 1-Cyclohexyl-4-(4-arylcyclohexyl)piperazines: Mixed σ and Human Δ<sub>8</sub>-Δ<sub>7</sub> Sterol Isomerase Ligands with Antiproliferative and P-Glycoprotein Inhibitory Activity (ChemMedChem 1/2011).

1-Cyclohexyl-4-(4-arylcyclohexyl)piperazines: Mixed σ and Human Δ<sub>8</sub>-Δ<sub>7</sub> Sterol Isomerase Ligands with Antiproliferative and P-Glycoprotein Inhibitory Activity.

Multi-Drug-Resistance-Reverting Agents: 2-Aryloxazole and 2-Arylthiazole Derivatives as Potent BCRP or MRP1 Inhibitors.

Impact of Partitioning Temperature Parameters during the Quenching and Partitioning Process on Medium Carbon Steels with Two Different Alloying Strategies.

Chiroptical properties of cyclic amines.

Selective agonists for serotonin 7 (5-HT<sub>7</sub>) receptor and their applications in preclinical models: an overview.

Functionalized Coumarine Fragment to Obtain Fluorescent and Selective P-Glycoprotein Ligands.

Synthesis and binding profile of constrained analogues of N-[4-(4-arylpiperazin-1-yl)butyl]-3-methoxybenzamides, a class of potent dopamine D3 receptor ligands.

Distribution of sigma receptors in EMT-6 cells: preliminary biological evaluation of PB167 and potential for in-vivo PET.

Design and synthesis of long-chain arylpiperazines with mixed affinity for serotonin transporter (SERT) and 5-HT1A receptor.

Studies on 1-arylpiperazine derivatives with affinity for rat 5-HT<sub>7</sub> and 5-HT<sub>1A</sub> receptors.

Radiosynthesis and in vivo Evaluation of Carbon-11 (2 S)-3-(1 H-Indol-3-yl)-2-{[(4-methoxyphenyl)carbamoyl]amino}- N-{[1-(5-methoxypyridin-2-yl)cyclohexyl]methyl}propanamide: An Attempt to Visualize Brain Formyl Peptide Receptors in Mouse Models of Neuroinflammation

Design, Synthesis, Lipophilic Properties, and Binding Affinities of Potential Ligands in Positron Emission Tomography (PET) for Visualization of Brain Dopamine D<sub>4</sub> Receptors.

Same Behaviour in Obtaining Azirines from 1-Tetralones and a 7-Oxo-tetrahydrobenzothiazole.

Chemical Studies on Drug Metabolism II. N-Demethylation and N-Oxidation of Some Alicyclic Amines by Ruthenium Tetroxide.