Works by Robbins, Paul D.

Results: 143

Imaging Secretory Vesicles by Fluorescent Protein Insertion in Propeptide Rather Than Mature Secreted Peptide.

Published in:

Traffic, 2002, v. 3, n. 7, p. 461, doi. 10.1034/j.1600-0854.2002.30703.x

By:

Watkins, Simon;
Geng, Xuehui;
Li, Lehong;
Papworth, Glenn;
Robbins, Paul D;
Drain, Peter

Publication type:

Article

Pharmacologic IKK/NF-κB inhibition causes antigen presenting cells to undergo TNFα dependent ROS-mediated programmed cell death.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep03631

By:

Tilstra, Jeremy S.;
Gaddy, Daniel F.;
Jing Zhao;
Davé, Shaival H.;
Niedernhofer, Laura J.;
Plevy, Scott E.;
Robbins, Paul D.

Publication type:

Article

The 2024 OREF Clinical Research Award: Progress Toward a Gene Therapy for Arthritis.

Published in:

Journal of the American Academy of Orthopaedic Surgeons, 2024, v. 32, n. 23, p. 1052, doi. 10.5435/JAAOS-D-24-00831

By:

Evans, Christopher H.;
Ghivizzani, Steven C.;
Robbins, Paul D.

Publication type:

Article

Hsp90 inhibitors as senolytic drugs to extend healthy aging.

Published in:

Cell Cycle, 2018, v. 17, n. 9, p. 1048, doi. 10.1080/15384101.2018.1475828

By:

Fuhrmann-Stroissnigg, Heike;
Niedernhofer, Laura J.;
Robbins, Paul D.

Publication type:

Article

mTOR signaling plays a critical role in the defects observed in muscle-derived stem/progenitor cells isolated from a murine model of accelerated aging.

Published in:

Journal of Orthopaedic Research, 2017, v. 35, n. 7, p. 1375, doi. 10.1002/jor.23409

By:

Takayama, Koji;
Kawakami, Yohei;
Lavasani, Mitra;
Mu, Xiaodong;
Cummins, James H.;
Yurube, Takashi;
Kuroda, Ryosuke;
Kurosaka, Masahiro;
Fu, Freddie H.;
Robbins, Paul D.;
Niedernhofer, Laura J.;
Huard, Johnny

Publication type:

Article

Mitochondrial-derived reactive oxygen species (ROS) play a causal role in aging-related intervertebral disc degeneration.

Published in:

Journal of Orthopaedic Research, 2013, v. 31, n. 7, p. 1150, doi. 10.1002/jor.22320

By:

Nasto, Luigi A.;
Robinson, Andria R.;
Ngo, Kevin;
Clauson, Cheryl L.;
Dong, Qing;
St. Croix, Claudette;
Sowa, Gwendolyn;
Pola, Enrico;
Robbins, Paul D.;
Kang, James;
Niedernhofer, Laura J.;
Wipf, Peter;
Vo, Nam V.

Publication type:

Article

An overview of underlying causes and animal models for the study of age-related degenerative disorders of the spine and synovial joints.

Published in:

Journal of Orthopaedic Research, 2013, v. 31, n. 6, p. 831, doi. 10.1002/jor.22204

By:

Vo, Nam;
Niedernhofer, Laura J.;
Nasto, Luigi Aurelio;
Jacobs, Lloydine;
Robbins, Paul D.;
Kang, James;
Evans, Christopher H.

Publication type:

Article

Accelerated aging of intervertebral discs in a mouse model of progeria.

Published in:

Journal of Orthopaedic Research, 2010, v. 28, n. 12, p. 1600, doi. 10.1002/jor.21153

By:

Vo, Nam;
Seo, Hyoung-Yeon;
Robinson, Andria;
Sowa, Gwendolyn;
Bentley, Douglas;
Taylor, Lauren;
Studer, Rebecca;
Usas, Arvydas;
Huard, Johnny;
Alber, Sean;
Watkins, Simon C.;
Lee, Joon;
Coehlo, Paulo;
Wang, Dong;
Loppini, Mattia;
Robbins, Paul D.;
Niedernhofer, Laura J.;
Kang, James

Publication type:

Article

Role of Cellular Senescence in Type II Diabetes.

Published in:

Endocrinology, 2021, v. 162, n. 10, p. 1, doi. 10.1210/endocr/bqab136

By:

Narasimhan, Akilavalli;
Flores, Rafael R;
Robbins, Paul D;
Niedernhofer, Laura J

Publication type:

Article

Immune Senescence, Immunosenescence and Aging.

Published in:

Frontiers in Aging, 2022, p. 1, doi. 10.3389/fragi.2022.900028

By:

Kyoo-A Lee;
Flores, Rafael R.;
In Hwa Jang;
Saathoff, Ashley;
Robbins, Paul D.

Publication type:

Article

Arsenic Promotes NF-Κb-Mediated Fibroblast Dysfunction and Matrix Remodeling to Impair Muscle Stem Cell Function.

Published in:

Stem Cells, 2016, v. 34, n. 3, p. 732, doi. 10.1002/stem.2232

By:

Zhang, Changqing;
Ferrari, Ricardo;
Beezhold, Kevin;
Stearns-Reider, Kristen;
D'Amore, Antonio;
Haschak, Martin;
Stolz, Donna;
Robbins, Paul D.;
Barchowsky, Aaron;
Ambrosio, Fabrisia

Publication type:

Article

Regulation of chronic inflammatory and immune processes by extracellular vesicles.

Published in:

2016

By:

Robbins, Paul D.;
Dorronsoro, Akaitz;
Booker, Cori N.

Publication type:

journal article

NF-κB inhibition delays DNA damage- induced senescence and aging in mice.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 7, p. 2601, doi. 10.1172/JCI45785

By:

Tilstra, Jeremy S.;
Robinson, Andria R.;
Wang, Jin;
Gregg, Siobhán Q.;
Clauson, Cheryl L.;
Reay, Daniel P.;
Nasto, Luigi A.;
St Croix, Claudette M.;
Usas, Arvydas;
Vo, Nam;
Huard, Johnny;
Clemens, Paula R.;
Stolz, Donna B.;
Guttridge, Denis C.;
Watkins, Simon C.;
Garinis, George A.;
Wang, Yinsheng;
Niedernhofer, Laura J.;
Robbins, Paul D.

Publication type:

Article

Regulation of immune responses by extracellular vesicles.

Published in:

Nature Reviews Immunology, 2014, v. 14, n. 3, p. 195, doi. 10.1038/nri3622

By:

Robbins, Paul D.;
Morelli, Adrian E.

Publication type:

Article

Reduction of senescent fibro‐adipogenic progenitors in progeria‐aged muscle by senolytics rescues the function of muscle stem cells.

Published in:

Journal of Cachexia, Sarcopenia & Muscle, 2022, v. 13, n. 6, p. 3137, doi. 10.1002/jcsm.13101

By:

Liu, Lei;
Yue, Xianlin;
Sun, Zewei;
Hambright, William S.;
Wei, Jianming;
Li, Ying;
Matre, Polina;
Cui, Yan;
Wang, Zhihui;
Rodney, George;
Huard, Johnny;
Robbins, Paul D.;
Mu, Xiaodong

Publication type:

Article

IL-Y, a synthetic member of the IL-12 cytokine family, suppresses the development of type 1 diabetes in NOD mice.

Published in:

European Journal of Immunology, 2015, v. 45, n. 11, p. 3114, doi. 10.1002/eji.201445403

By:

Flores, Rafael R.;
Kim, Eun;
Zhou, Liqiao;
Yang, Chenjie;
Zhao, Jing;
Gambotto, Andrea;
Robbins, Paul D.

Publication type:

Article

Plasma-derived MHC class II+ exosomes from tumor-bearing mice suppress tumor antigen-specific immune responses.

Published in:

European Journal of Immunology, 2012, v. 42, n. 7, p. 1778, doi. 10.1002/eji.201141978

By:

Yang, Chenjie;
Ruffner, Melanie A.;
Kim, Seon-Hee;
Robbins, Paul D.

Publication type:

Article

A phase 1 clinical trial shows safe, sustained, AAV-mediated expression of IL-1Ra in the human osteoarthritic knee joint.

Published in:

Science Translational Medicine, 2025, v. 17, n. 801, p. 1, doi. 10.1126/scitranslmed.adu9804

By:

De la Vega, Rodolfo E.;
Sellon, Jacob L.;
Smith, Jay;
Wisniewski, Stephen J.;
Jurisson, Mary L.;
Frick, Matthew A.;
Scrabeck, Tyson L.;
Block, Julie B.;
Mills, Candee J.;
Pohlkamp, Zachary W.;
Coenen, Michael J.;
Hawse, Gresin P.;
Abdul, Temilola Y.;
Conaghan, Philip;
Keravala, Annahita;
Chalberg, Thomas W.;
Robbins, Paul D.;
Ghivizzani, Steven C.;
Evans, Christopher H.

Publication type:

Article

B-cell interleukin 1 receptor 1 modulates the female adipose tissue immune microenvironment during aging.

Published in:

Journal of Leukocyte Biology, 2025, v. 117, n. 2, p. 1, doi. 10.1093/jleuko/qiae219

By:

Carey, Anna;
Pitcher, Louise E;
Jang, In Hwa;
Nguyen, Katie;
Cholensky, Stephanie;
Robbins, Paul D;
Camell, Christina D

Publication type:

Article

Gene transfer to the tendon-bone insertion site.

Published in:

2004

By:

Lattermann, Christian;
Zelle, Boris A.;
Whalen, Janey D.;
Baltzer, Axel W.A.;
Robbins, Paul;
Niyibizi, Christopher;
Evans, Christopher H.;
Fu, Freddie H.;
Robbins, Paul D

Publication type:

journal article

Hitting the Bullseye: Are extracellular vesicles on target?

Published in:

Journal of Extracellular Vesicles, 2020, v. 10, p. 1, doi. 10.1002/jev2.12032

By:

Noren Hooten, Nicole;
Yáñez‐Mó, María;
DeRita, Rachel;
Russell, Ashley;
Quesenberry, Peter;
Ramratnam, Bharat;
Robbins, Paul D.;
Di Vizio, Dolores;
Wen, Sicheng;
Witwer, Kenneth W.;
Languino, Lucia R.

Publication type:

Article

Hitting the Bullseye: Are extracellular vesicles on target?

Published in:

Journal of Extracellular Vesicles, 2020, v. 10, n. 1, p. 1, doi. 10.1002/jev2.12032

By:

Noren Hooten, Nicole;
Yáñez‐Mó, María;
DeRita, Rachel;
Russell, Ashley;
Quesenberry, Peter;
Ramratnam, Bharat;
Robbins, Paul D.;
Di Vizio, Dolores;
Wen, Sicheng;
Witwer, Kenneth W.;
Languino, Lucia R.

Publication type:

Article

A new gene set identifies senescent cells and predicts senescence-associated pathways across tissues.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32552-1

By:

Saul, Dominik;
Kosinsky, Robyn Laura;
Atkinson, Elizabeth J.;
Doolittle, Madison L.;
Zhang, Xu;
LeBrasseur, Nathan K.;
Pignolo, Robert J.;
Robbins, Paul D.;
Niedernhofer, Laura J.;
Ikeno, Yuji;
Jurk, Diana;
Passos, João F.;
Hickson, LaTonya J.;
Xue, Ailing;
Monroe, David G.;
Tchkonia, Tamara;
Kirkland, James L.;
Farr, Joshua N.;
Khosla, Sundeep

Publication type:

Article

Regenerating the injured kidney with human umbilical cord mesenchymal stem cell-derived exosomes.

Published in:

Stem Cell Research & Therapy, 2013, v. 4, n. 2, p. 1, doi. 10.1186/scrt187

By:

Dorronsoro, Akaitz;
Robbins, Paul D.

Publication type:

Article

Dedifferentiation rescues senescence of progeria cells but only while pluripotent.

Published in:

Stem Cell Research & Therapy, 2011, v. 2, n. 3, p. 1, doi. 10.1186/scrt69

By:

Niedernhofer, Laura J.;
Glorioso, Joseph C.;
Robbins, Paul D.

Publication type:

Article

Immunosuppressive Exosomes: A New Approach for Treating Arthritis.

Published in:

International Journal of Rheumatology, 2012, p. 1, doi. 10.1155/2012/573528

By:

Chenjie Yang;
Robbins, Paul D.

Publication type:

Article

Inhibition of NF-κB improves the stress resistance and myogenic differentiation of MDSPCs isolated from naturally aged mice.

Published in:

PLoS ONE, 2017, v. 12, n. 6, p. 1, doi. 10.1371/journal.pone.0179270

By:

Proto, Jonathan D.;
Scibetta, Alex;
Lu, Aiping;
Huard, Johnny;
Dorronsoro, Akaitz;
Robbins, Paul D.;
Niedernhofer, Laura J.

Publication type:

Article

Expression and Activity of the CDK Inhibitor p57Kip2 in Chondrocytes Undergoing Hypertrophic Differentiation.

Published in:

Journal of Bone & Mineral Research, 2004, v. 19, n. 1, p. 123, doi. 10.1359/jbmr.0301209

By:

Stewart, Matthew C;
Kadlcek, Renata M;
Robbins, Paul D;
Macleod, James N;
Ballock, R Tracy

Publication type:

Article

Creating the Next Generation of Translational Geroscientists.

Published in:

Journal of the American Geriatrics Society, 2019, v. 67, n. 9, p. 1934, doi. 10.1111/jgs.16055

By:

Newman, John C.;
Sokoloski, Julie L.;
Robbins, Paul D.;
Niedernhofer, Laura J.;
Reed, May J.;
Wei, Jeanne;
Austad, Steven N.;
Barzilai, Nir;
Cohen, Harvey Jay;
Kuchel, George A.;
Kirkland, James L.;
Pignolo, Robert J.

Publication type:

Article

The Clinical Potential of Senolytic Drugs.

Published in:

Journal of the American Geriatrics Society, 2017, v. 65, n. 10, p. 2297, doi. 10.1111/jgs.14969

By:

Kirkland, James L.;
Tchkonia, Tamara;
Zhu, Yi;
Niedernhofer, Laura J.;
Robbins, Paul D.

Publication type:

Article

Interleukm-1 receptor antagonist suppresses neurotrophin response in injured rat brain.

Published in:

Annals of Neurology, 1996, v. 39, n. 1, p. 123, doi. 10.1002/ana.410390118

By:

Dekosky, Steven T.;
Styren, Scot D.;
O'Malley, Mark E.;
Goss, James R.;
Kochanek, Patrick;
Marion, Donald;
Evans, Christopher H.;
Robbins, Paul D.

Publication type:

Article

The Roles of Tumor-Derived Exosomes in Cancer Pathogenesis.

Published in:

Clinical & Developmental Immunology, 2011, p. 1, doi. 10.1155/2011/842849

By:

Chenjie Yang;
Robbins, Paul D.

Publication type:

Article

Rb interacts with TAFII250/TFIID through multiple domains.

Published in:

Oncogene, 1997, v. 15, n. 4, p. 385, doi. 10.1038/sj.onc.1201204

By:

Shaos, Zhaohui;
Siegert, Jennifer L;
Ruppert, Siegfried;
Robbins, Paul D

Publication type:

Article

Natural killer, but not natural killer T, cells play a necessary role in the promotion of an innate antitumor response induced by IL-18.

Published in:

International Journal of Cancer, 2003, v. 103, n. 4, p. 508, doi. 10.1002/ijc.10844

By:

Hashimoto, Wataru;
Tanaka, Fumiaki;
Robbins, Paul D.;
Taniguchi, Masaru;
Okamura, Haruki;
Lotze, Michael T.;
Tahara, Hideaki

Publication type:

Article

NF-κB in Aging and Disease.

Published in:

Aging & Disease, 2011, v. 2, n. 6, p. 449

By:

Tilstra, Jeremy S.;
Clauson, Cheryl L.;
Niedernhofer, Laura J.;
Robbins, Paul D.

Publication type:

Article

Dual transduction of insulin-like growth factor-I and interleukin-1 receptor antagonist protein controls cartilage degradation in an osteoarthritic culture model

Published in:

Journal of Orthopaedic Research, 2005, v. 23, n. 1, p. 118, doi. 10.1016/j.orthres.2004.06.020

By:

Haupt, Jennifer L.;
Frisbie, David D.;
McIlwraith, C. Wayne;
Robbins, Paul D.;
Ghivizzani, Steve;
Evans, Chris H.;
Nixon, Alan J.

Publication type:

Article

Gene mediated insulin-like growth factor-I delivery to the synovium.

Published in:

Journal of Orthopaedic Research, 2001, v. 19, n. 5, p. 759, doi. 10.1016/S0736-0266(00)00077-2

By:

Saxer, Rachel A.;
Bent, Stephen J.;
Brower-Toland, Brent D.;
Mi, Zhibao;
Robbins, Paul D.;
Evans, Christopher H.;
Nixon, Alan J.

Publication type:

Article

Osteoprogenitor cells within skeletal muscle.

Published in:

Journal of Orthopaedic Research, 2000, v. 18, n. 6, p. 933, doi. 10.1002/jor.1100180613

By:

Bosch, Patrick;
Musgrave, Douglas S.;
Lee, Joon Yung;
Cummins, Jim;
Shuler, Franklin;
Ghivizzani, Steven C.;
Evans, Chris;
Robbins, Paul D.;
Huard, Johnny

Publication type:

Article

Increased matrix synthesis following adenoviral transfer of a transforming growth factor β1 gene into articular chondrocytes.

Published in:

Journal of Orthopaedic Research, 2000, v. 18, n. 4, p. 585, doi. 10.1002/jor.1100180411

By:

Shuler, Franklin D.;
Georgescu, Helga I.;
Niyibizi, Christopher;
Studer, Rebecca K.;
Mi, Zhibao;
Johnstone, Brian;
Robbins, Paul D.;
Evans, Christopher H.

Publication type:

Article

Early expression of marker genes in the rabbit medial collateral and anterior cruciate ligaments: The use of different viral vectors and the effects of injury.

Published in:

Journal of Orthopaedic Research, 1999, v. 17, n. 1, p. 37, doi. 10.1002/jor.1100170107

By:

Hildebrand, Kevin A.;
Deie, Masataka;
Allen, Christina R.;
Smith, David W.;
Georgescu, Helga I.;
Evans, Christopher H.;
Robbins, Paul D.;
Woo, Savio L-Y.

Publication type:

Article

Aging and chronic inflammation: highlights from a multidisciplinary workshop.

Published in:

Immunity & Ageing, 2023, v. 20, n. 1, p. 1, doi. 10.1186/s12979-023-00352-w

By:

Saavedra, Danay;
Añé-Kourí, Ana Laura;
Barzilai, Nir;
Caruso, Calogero;
Cho, Kyung-Hyun;
Fontana, Luigi;
Franceschi, Claudio;
Frasca, Daniela;
Ledón, Nuris;
Niedernhofer, Laura J.;
Pereira, Karla;
Robbins, Paul D.;
Silva, Alexa;
Suarez, Gisela M.;
Berghe, Wim Vanden;
von Zglinicki, Thomas;
Pawelec, Graham;
Lage, Agustín

Publication type:

Article

Intra-articular gene delivery and expression of interleukin-1Ra mediated by self-complementary adeno-associated virus.

Published in:

Journal of Gene Medicine, 2009, v. 11, n. 7, p. 605, doi. 10.1002/jgm.1334

By:

Kay, Jesse D.;
Gouze, Elvire;
Oligino, Thomas J.;
Gouze, Jean-Noel;
Watson, Rachael S.;
Levings, Padraic P.;
Bush, Marsha L.;
Dacanay, Anthony;
Nickerson, David M.;
Robbins, Paul D.;
Evans, Christopher H.;
Ghivizzani, Steven C.

Publication type:

Article

PhiC31 integrase mediates integration in cultured synovial cells and enhances gene expression in rabbit joints.

Published in:

Journal of Gene Medicine, 2006, v. 8, n. 8, p. 1008, doi. 10.1002/jgm.928

By:

Keravala, Annahita;
Portlock, Joylette L.;
Nash, Joan A.;
Vitrant, David G.;
Robbins, Paul D.;
Calos, Michele P.

Publication type:

Article

Comparative analysis of antitumor activity of CD40L, RANKL, and 4-1BBL in vivo following intratumoral administration of viral vectors or transduced dendritic cells.

Published in:

Journal of Gene Medicine, 2006, v. 8, n. 2, p. 129, doi. 10.1002/jgm.834

By:

Yurkovetsky, Zoya R.;
Shurin, Galina V.;
Barry, Denise A.;
Schuh, Andre C.;
Shurin, Michael R.;
Robbins, Paul D.

Publication type:

Article

Comparative analysis of dendritic cells transduced with different anti-apoptotic molecules: sensitivity to tumor-induced apoptosis.

Published in:

Journal of Gene Medicine, 2004, v. 6, n. 5, p. 537, doi. 10.1002/jgm.545

By:

Balkir, Levent;
Tourkova, Irina L.;
Makarenkova, Valeria P.;
Shurin, Galina V.;
Robbins, Paul D.;
Yin, Xiao-Ming;
Chatta, Gurkamal;
Shurin, Michael R.

Publication type:

Article

A machine learning approach identifies cellular senescence on transcriptome data of human cells in vitro.

Published in:

GeroScience, 2025, v. 47, n. 3, p. 5287, doi. 10.1007/s11357-024-01485-6

By:

Mahmud, Shamsed;
Zheng, Chen;
Santiago, Fernando E.;
Zhang, Lei;
Robbins, Paul D.;
Dong, Xiao

Publication type:

Article

miR-146a-5p modulates cellular senescence and apoptosis in visceral adipose tissue of long-lived Ames dwarf mice and in cultured pre-adipocytes.

Published in:

GeroScience, 2022, v. 44, n. 1, p. 503, doi. 10.1007/s11357-021-00490-3

By:

Nunes, Allancer D. C.;
Weigl, Moritz;
Schneider, Augusto;
Noureddine, Sarah;
Yu, Lin;
Lahde, Collin;
Saccon, Tatiana Dandolini;
Mitra, Kunal;
Beltran, Esther;
Grillari, Johannes;
Kirkland, James L.;
Tchkonia, Tamara;
Robbins, Paul D.;
Masternak, Michal M.

Publication type:

Article

Heterochronic parabiosis regulates the extent of cellular senescence in multiple tissues.

Published in:

GeroScience, 2020, v. 42, n. 3, p. 951, doi. 10.1007/s11357-020-00185-1

By:

Yousefzadeh, Matthew J.;
Wilkinson, John E.;
Hughes, Brian;
Gadela, Namrata;
Ladiges, Warren C.;
Vo, Nam;
Niedernhofer, Laura J.;
Huffman, Derek M.;
Robbins, Paul D.

Publication type:

Article

NF-κB Negatively Impacts the Myogenic Potential of Muscle-derived Stem Cells.

Published in:

Molecular Therapy, 2012, v. 20, n. 3, p. 661, doi. 10.1038/mt.2011.261

By:

Lu, Aiping;
Proto, Jonathan D;
Guo, Lulin;
Tang, Ying;
Lavasani, Mitra;
Tilstra, Jeremy S;
Niedernhofer, Laura J;
Wang, Bing;
Guttridge, Denis C;
Robbins, Paul D;
Huard, Johnny

Publication type:

Article

Orthopedic Gene Therapy in 2008.

Published in:

Molecular Therapy, 2009, v. 17, n. 2, p. 231, doi. 10.1038/mt.2008.265

By:

Evans, Christopher H.;
Ghivizzani, Steven C.;
Robbins, Paul D.

Publication type:

Article