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Ex vivo propagation of synaptically-evoked cortical depolarizations in a mouse model of Alzheimer's disease at 20 Hz, 40 Hz, or 83 Hz.
- Published in:
- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-74262-2
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- Publication type:
- Article
ER‐stress response in retinal Müller glia occurs significantly earlier than amyloid pathology in the Alzheimer's mouse brain and retina.
- Published in:
- Glia, 2024, v. 72, n. 6, p. 1067, doi. 10.1002/glia.24514
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- Publication type:
- Article
Identification of rare <italic>RTN3</italic> variants in Alzheimer’s disease in Han Chinese.
- Published in:
- Human Genetics, 2018, v. 137, n. 2, p. 141, doi. 10.1007/s00439-018-1868-1
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- Publication type:
- Article
Effects of altered RTN3 expression on BACE1 activity and Alzheimer's neuritic plaques.
- Published in:
- Reviews in the Neurosciences, 2017, v. 28, n. 2, p. 145, doi. 10.1515/revneuro-2016-0054
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- Publication type:
- Article
Reduced Amyloid Deposition in Mice Overexpressing RTN3 Is Adversely Affected by Preformed Dystrophic Neurites.
- Published in:
- Journal of Neuroscience, 2009, v. 29, n. 29, p. 9163, doi. 10.1523/JNEUROSCI.5741-08.2009
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- Publication type:
- Article
The Occurrence of Aging-Dependent Reticulon 3 Immunoreactive Dystrophic Neurites Decreases Cognitive Function.
- Published in:
- Journal of Neuroscience, 2009, v. 29, n. 16, p. 5108, doi. 10.1523/JNEUROSCI.5887-08.2009
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- Publication type:
- Article
Homogeneity of active demyelinating lesions in established multiple sclerosis.
- Published in:
- Annals of Neurology, 2008, v. 63, n. 1, p. 16, doi. 10.1002/ana.21311
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- Publication type:
- Article
Regulatory role of cathepsin L in induction of nuclear laminopathy in Alzheimer's disease.
- Published in:
- Aging Cell, 2022, v. 21, n. 1, p. 1, doi. 10.1111/acel.13531
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- Publication type:
- Article
Transgenic mice overexpressing reticulon 3 develop neuritic abnormalities.
- Published in:
- EMBO Journal, 2007, v. 26, n. 11, p. 2755, doi. 10.1038/sj.emboj.7601707
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- Publication type:
- Article
Inhibition of BACE1 in glial cells for enhancing clearance of amyloid plaques.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.083297
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- Publication type:
- Article
Reversing hypomyelination in BACE1-null mice with Akt-DD overexpression.
- Published in:
- FASEB Journal, 2013, v. 27, n. 5, p. 1868, doi. 10.1096/fj.12-224212
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- Publication type:
- Article
Interaction between amyloid precursor protein and Nogo receptors regulates amyloid deposition.
- Published in:
- FASEB Journal, 2011, v. 25, n. 9, p. 3146, doi. 10.1096/fj.11-184325
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- Publication type:
- Article
Genetic deletion of BACE1 in mice affects remyelination of sciatic nerves.
- Published in:
- FASEB Journal, 2008, v. 22, n. 8, p. 2970, doi. 10.1096/fj.08-106666
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- Publication type:
- Article
Bace1 modulates myelination in the central and peripheral nervous system.
- Published in:
- Nature Neuroscience, 2006, v. 9, n. 12, p. 1520, doi. 10.1038/nn1797
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- Publication type:
- Article
A Close Look at BACE1 Inhibitors for Alzheimer's Disease Treatment.
- Published in:
- 2019
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- Publication type:
- journal article
Neurological dysfunctions associated with altered BACE1-dependent Neuregulin-1 signaling.
- Published in:
- Journal of Neurochemistry, 2016, v. 136, n. 2, p. 234, doi. 10.1111/jnc.13395
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- Publication type:
- Article
NOGO is increased and binds to BACE1 in sporadic inclusion-body myositis and in AβPP-overexpressing cultured human muscle fibers.
- Published in:
- Acta Neuropathologica, 2007, v. 114, n. 5, p. 517, doi. 10.1007/s00401-007-0281-y
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- Publication type:
- Article
The sterol regulatory element‐binding protein 2 is dysregulated by tau alterations in Alzheimer disease.
- Published in:
- Brain Pathology, 2019, v. 29, n. 4, p. 530, doi. 10.1111/bpa.12691
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- Publication type:
- Article
BACE1 regulates expression of Clusterin in astrocytes for enhancing clearance of β-amyloid peptides.
- Published in:
- Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00611-w
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- Publication type:
- Article
APPswe/Aβ regulation of osteoclast activation and RAGE expression in an age-dependent manner.
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- Journal of Bone & Mineral Research, 2011, v. 26, n. 5, p. 1084, doi. 10.1002/jbmr.299
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- Publication type:
- Article
Widespread distribution of reticulon-3 in various neurodegenerative diseases.
- Published in:
- Neuropathology, 2010, v. 30, n. 6, p. 574, doi. 10.1111/j.1440-1789.2010.01107.x
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- Publication type:
- Article
Role of BACE1 in Alzheimer's synaptic function.
- Published in:
- Translational Neurodegeneration, 2017, v. 6, n. 1, p. 1, doi. 10.1186/s40035-017-0093-5
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- Publication type:
- Article
Stepping closer to treating Alzheimer's disease patients with BACE1 inhibitor drugs.
- Published in:
- Translational Neurodegeneration, 2016, v. 5, p. 1, doi. 10.1186/s40035-016-0061-5
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- Publication type:
- Article
Reticulon family members modulate BACE1 activity and amyloid-ßpeptide generation.
- Published in:
- Nature Medicine, 2004, v. 10, n. 9, p. 959, doi. 10.1038/nm1088
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- Publication type:
- Article
Elevated β-secretase expression and enzymatic activity detected in sporadic Alzheimer disease.
- Published in:
- Nature Medicine, 2003, v. 9, n. 1, p. 3, doi. 10.1038/nm0103-3
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- Publication type:
- Article
Axonal and Schwann Cell BACE1 Is Equally Required for Remyelination of Peripheral Nerves.
- Published in:
- Journal of Neuroscience, 2015, v. 35, n. 9, p. 3806, doi. 10.1523/JNEUROSCI.5207-14.2015
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- Publication type:
- Article
Impact of RTN3 Deficiency on Expression of BACE1 and Amyloid Deposition.
- Published in:
- Journal of Neuroscience, 2014, v. 34, n. 42, p. 13954, doi. 10.1523/JNEUROSCI.1588-14.2014
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- Publication type:
- Article
Preventing Formation of Reticulon 3 Immunoreactive Dystrophic Neurites Improves Cognitive Function in Mice.
- Published in:
- Journal of Neuroscience, 2013, v. 33, n. 7, p. 3059, doi. 10.1523/JNEUROSCI.2445-12.2013
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- Publication type:
- Article
BACE1 Deficiency Causes Altered Neuronal Activity and Neurodegeneration.
- Published in:
- Journal of Neuroscience, 2010, v. 30, n. 26, p. 8819, doi. 10.1523/JNEUROSCI.1334-10.2010
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- Publication type:
- Article
The β-Secretase Enzyme BACE in Health and Alzheimer's Disease: Regulation, Cell Biology, Function, and Therapeutic Potential.
- Published in:
- Journal of Neuroscience, 2009, v. 29, n. 41, p. 12787, doi. 10.1523/JNEUROSCI.3657-09.2009
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- Publication type:
- Article
Deletion of neuronal BACE1 causes mice memory deficits: Molecular and cell biology/APP/Abeta/amyloid.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043965
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- Publication type:
- Article
A novel interaction between AD risk genes synaptojanin 1 and reticulon‐3 potentially impacts synaptic function and endo‐lysosomal trafficking during disease development and progression: Molecular and cell biology: Endo‐lysosomal/trafficking dysfunction
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043247
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- Publication type:
- Article
Dynactin 6 deficiency enhances tubular ER‐associated dystrophic neurites formation: Molecular and cell biology/axonal transport.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043049
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- Publication type:
- Article
P1‐206: THE CONSTITUTION OF DYSTROPHIC NEURITES IN AGING AND IN ALZHEIMER'S DISEASE MOUSE MODEL BRAIN AND THEIR 3D STRUCTURES.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P358, doi. 10.1016/j.jalz.2018.06.211
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- Publication type:
- Article
O1-03-01: Reduced amyloid deposition in mice overexpressing RTN3 is adversely affected by preformed dystrophic neurites
- Published in:
- 2008
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- Publication type:
- Abstract
Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity.
- Published in:
- Nature, 1999, v. 402, n. 6761, p. 533, doi. 10.1038/990107
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- Publication type:
- Article
Exploration of C-terminal CX3CL1 for reducing age-dependent neurodegeneration.
- Published in:
- Neural Regeneration Research, 2023, v. 18, n. 12, p. 2667, doi. 10.4103/1673-5374.373702
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- Publication type:
- Article
Physiological Functions of the β-Site Amyloid Precursor Protein Cleaving Enzyme 1 and 2.
- Published in:
- Frontiers in Molecular Neuroscience, 2017, p. 1, doi. 10.3389/fnmol.2017.00097
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- Publication type:
- Article
Accumulation of saposin in dystrophic neurites is linked to impaired lysosomal functions in Alzheimer's disease brains.
- Published in:
- Molecular Neurodegeneration, 2021, v. 16, n. 1, p. 1, doi. 10.1186/s13024-021-00464-1
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- Publication type:
- Article
Activity of Alzheimer's γ-secretase is linked to changes of interferon-induced transmembrane proteins (IFITM) in innate immunity.
- Published in:
- 2020
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- Publication type:
- Letter
Activated CX3CL1/Smad2 Signals Prevent Neuronal Loss and Alzheimer's Tau Pathology-Mediated Cognitive Dysfunction.
- Published in:
- Journal of Neuroscience, 2020, v. 40, n. 5, p. 1133, doi. 10.1523/jneurosci.1333-19.2019
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- Publication type:
- Article
BACE1 regulates the proliferation and cellular functions of Schwann cells.
- Published in:
- Glia, 2017, v. 65, n. 5, p. 712, doi. 10.1002/glia.23122
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- Publication type:
- Article
β-Secretase1 biological markers for Alzheimer's disease: state-of-art of validation and qualification.
- Published in:
- Alzheimer's Research & Therapy, 2020, v. 12, n. 1, p. N.PAG, doi. 10.1186/s13195-020-00686-3
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- Publication type:
- Article
Reticulon 3 aggregation and its role in the formation of dystrophic neurites.
- Published in:
- 2012
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- Publication type:
- Abstract
Changes in γ-secretase activity and specificity caused by the introduction of consensus aspartyl protease active motif in Presenilin 1.
- Published in:
- Molecular Neurodegeneration, 2008, v. 3, p. 1, doi. 10.1186/1750-1326-3-6
- By:
- Publication type:
- Article
Bace1 Deletion in the Adult Reverses Epileptiform Activity and Sleep-wake Disturbances in AD Mice.
- Published in:
- Journal of Neuroscience, 2023, v. 43, n. 35, p. 6197, doi. 10.1523/JNEUROSCI.2124-22.2023
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- Publication type:
- Article
Linking APOE4/4 genotype to microglial lipid droplets and neurotoxicity in Alzheimer's disease.
- Published in:
- Translational Neurodegeneration, 2024, v. 13, n. 1, p. 1, doi. 10.1186/s40035-024-00433-w
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- Publication type:
- Article
Employing a superior BACE1 cleavage sequence to probe cellular APP processing.
- Published in:
- Journal of Neurochemistry, 2003, v. 84, n. 5, p. 1006, doi. 10.1046/j.1471-4159.2003.01597.x
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- Publication type:
- Article
Alzheimer's disease amyloidogenesis is linked to altered lower urinary tract physiology.
- Published in:
- Neurourology & Urodynamics, 2022, v. 41, n. 6, p. 1344, doi. 10.1002/nau.24952
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- Publication type:
- Article
Reticulons 1 and 3 are essential for axonal growth and synaptic maintenance associated with intellectual development.
- Published in:
- Human Molecular Genetics, 2023, v. 32, n. 16, p. 2587, doi. 10.1093/hmg/ddad085
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- Publication type:
- Article