Works by Ripatti, Samuli

Results: 109
    1

    Mitochondrial genome copy number measured by DNA sequencing in human blood is strongly associated with metabolic traits via cell-type composition differences.

    Published in:
    Human Genomics, 2021, v. 15, n. 1, p. 1, doi. 10.1186/s40246-021-00335-2
    By:
    • Ganel, Liron;
    • Chen, Lei;
    • Christ, Ryan;
    • Vangipurapu, Jagadish;
    • Young, Erica;
    • Das, Indraniel;
    • Kanchi, Krishna;
    • Larson, David;
    • Regier, Allison;
    • Abel, Haley;
    • Kang, Chul Joo;
    • Scott, Alexandra;
    • Havulinna, Aki;
    • Chiang, Charleston W. K.;
    • Service, Susan;
    • Freimer, Nelson;
    • Palotie, Aarno;
    • Ripatti, Samuli;
    • Kuusisto, Johanna;
    • Boehnke, Michael
    Publication type:
    Article
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    Assessing the potential causal effects of 1099 plasma metabolites on 2099 binary disease endpoints.

    Published in:
    Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-58129-2
    By:
    • Yin, Xianyong;
    • Li, Jack;
    • Bose, Debraj;
    • Okamoto, Jeffrey;
    • Kwon, Annie;
    • Jackson, Anne U.;
    • Fernandes Silva, Lilian;
    • Oravilahti, Anniina;
    • Chu, Xiaomeng;
    • Stringham, Heather M.;
    • Liu, Lei;
    • Peng, Ruyi;
    • Xia, Zhijie;
    • Ripatti, Samuli;
    • Daly, Mark;
    • Palotie, Aarno;
    • Scott, Laura J.;
    • Burant, Charles F.;
    • Fauman, Eric B.;
    • Wen, Xiaoquan
    Publication type:
    Article
    11

    Socio-demographic and genetic risk factors for drug adherence and persistence across 5 common medication classes.

    Published in:
    Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-53556-z
    By:
    • Cordioli, Mattia;
    • Corbetta, Andrea;
    • Kariis, Hanna Maria;
    • Jukarainen, Sakari;
    • Vartiainen, Pekka;
    • Kiiskinen, Tuomo;
    • Ferro, Matteo;
    • FinnGen;
    • Perola, Markus;
    • Ripatti, Samuli;
    • Ganna, Andrea;
    • Metspalu, Andres;
    • Milani, Lili;
    • Esko, Tõnu;
    • Mägi, Reedik;
    • Nelis, Mari;
    • Hudjashov, Georgi;
    • Niemi, Mikko;
    • Lehto, Kelli
    Publication type:
    Article
    12
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    Genomic prediction of coronary heart disease.

    Published in:
    European Heart Journal, 2016, v. 37, n. 43, p. 3267, doi. 10.1093/eurheartj/ehw450
    By:
    • Abraham, Gad;
    • Havulinna, Aki S.;
    • Bhalala, Oneil G.;
    • Byars, Sean G.;
    • De Livera, Alysha M.;
    • Yetukuri, Laxman;
    • Tikkanen, Emmi;
    • Perola, Markus;
    • Schunkert, Heribert;
    • Sijbrands, Eric J.;
    • Palotie, Aarno;
    • Samani, Nilesh J.;
    • Salomaa, Veikko;
    • Ripatti, Samuli;
    • Inouye, Michael
    Publication type:
    Article
    14
    15

    Longitudinal multi-omics study reveals common etiology underlying association between plasma proteome and BMI trajectories in adolescent and young adult twins.

    Published in:
    BMC Medicine, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12916-023-03198-7
    By:
    • Drouard, Gabin;
    • Hagenbeek, Fiona A.;
    • Whipp, Alyce M.;
    • Pool, René;
    • Hottenga, Jouke Jan;
    • Jansen, Rick;
    • Hubers, Nikki;
    • Afonin, Aleksei;
    • Willemsen, Gonneke;
    • de Geus, Eco J. C.;
    • Ripatti, Samuli;
    • Pirinen, Matti;
    • Kanninen, Katja M.;
    • Boomsma, Dorret I.;
    • van Dongen, Jenny;
    • Kaprio, Jaakko
    Publication type:
    Article
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    An interaction map of circulating metabolites, immune gene networks, and their genetic regulation.

    Published in:
    Genome Biology, 2017, v. 18, p. 1, doi. 10.1186/s13059-017-1279-y
    By:
    • Nath, Artika P.;
    • Ritchie, Scott C.;
    • Byars, Sean G.;
    • Fearnley, Liam G.;
    • Havulinna, Aki S.;
    • Joensuu, Anni;
    • Kangas, Antti J.;
    • Soininen, Pasi;
    • Wennerström, Annika;
    • Milani, Lili;
    • Metspalu, Andres;
    • Männistö, Satu;
    • Würtz, Peter;
    • Kettunen, Johannes;
    • Raitoharju, Emma;
    • Kähönen, Mika;
    • Juonala, Markus;
    • Palotie, Aarno;
    • Ala-Korpela, Mika;
    • Ripatti, Samuli
    Publication type:
    Article
    20

    Allele-specific regulation of DISC1 expression by miR-135b-5p.

    Published in:
    European Journal of Human Genetics, 2014, v. 22, n. 6, p. 840, doi. 10.1038/ejhg.2013.246
    By:
    • Rossi, Mari;
    • Kilpinen, Helena;
    • Muona, Mikko;
    • Surakka, Ida;
    • Ingle, Catherine;
    • Lahtinen, Jenni;
    • Hennah, William;
    • Ripatti, Samuli;
    • Hovatta, Iiris
    Publication type:
    Article
    21

    NordicDB: a Nordic pool and portal for genome-wide control data.

    Published in:
    European Journal of Human Genetics, 2010, v. 18, n. 12, p. 1322, doi. 10.1038/ejhg.2010.112
    By:
    • Leu, Monica;
    • Humphreys, Keith;
    • Surakka, Ida;
    • Rehnberg, Emil;
    • Juha Muilu;
    • Rosenström, Päivi;
    • Almgren, Peter;
    • Jääskeläinen, Juha;
    • Lifton, Richard P.;
    • Kyvik, Kirsten Ohm;
    • Kaprio, Jaakko;
    • Pedersen, Nancy L.;
    • Palotie, Aarno;
    • Hall, Per;
    • Grönberg, Henrik;
    • Groop, Leif;
    • Peltonen, Leena;
    • Palmgren, Juni;
    • Ripatti, Samuli
    Publication type:
    Article
    22

    GENESTAT: an information portal for design and analysis of genetic association studies.

    Published in:
    European Journal of Human Genetics, 2009, v. 17, n. 4, p. 533, doi. 10.1038/ejhg.2008.216
    By:
    • Ripatti, Samuli;
    • Becker, Tim;
    • Bickeböller, Heike;
    • Dominicus, Annica;
    • Fischer, Christine;
    • Humphreys, Keith;
    • Jonasdottir, Gudrun;
    • Moreau, Yves;
    • Olsson, Marita;
    • Ploner, Alexander;
    • Sheehan, Nuala;
    • Van Steen, Kristel;
    • Baur, Max;
    • van Duijn, Cornelia;
    • Palmgren, Juni
    Publication type:
    Article
    23

    Clinical utility and implementation of polygenic risk scores for predicting cardiovascular disease: A clinical consensus statement of the ESC Council on Cardiovascular Genomics, the ESC Cardiovascular Risk Collaboration, and the European Association of Preventive Cardiology

    Published in:
    European Heart Journal, 2025, v. 46, n. 15, p. 1372, doi. 10.1093/eurheartj/ehae649
    By:
    • Schunkert, Heribert;
    • Angelantonio, Emanuele Di;
    • Inouye, Michael;
    • Patel, Riyaz S;
    • Ripatti, Samuli;
    • Widen, Elisabeth;
    • Sanderson, Saskia C;
    • Kaski, Juan Pablo;
    • McEvoy, John W;
    • Vardas, Panos;
    • Wood, Angela;
    • Aboyans, Victor;
    • Vassiliou, Vassilios S;
    • Visseren, Frank L J;
    • Lopes, Luis R;
    • Elliott, Perry;
    • Kavousi, Maryam
    Publication type:
    Article
    24

    EU‐LIFE charter of independent life science research institutes.

    Published in:
    FEBS Letters, 2024, v. 598, n. 7, p. 719, doi. 10.1002/1873-3468.14855
    By:
    • Superti‐Furga, Giulio;
    • Agostinho, Marta;
    • Bury, Jo;
    • Cook, Simon;
    • Durinx, Christine;
    • Ender, Anita;
    • van Luenen, Henri;
    • Lund, Anders H.;
    • Medema, René H.;
    • Miączyńska, Marta;
    • Nickel, Dorthe;
    • Pelicci, Pier Giuseppe;
    • Puisieux, Alain;
    • Ripatti, Samuli;
    • Sander, Maike;
    • Schubeler, Dirk;
    • Serrano, Luis;
    • Sommer, Thomas;
    • Sonne‐Hansen, Katrine;
    • Tomančák, Pavel
    Publication type:
    Article
    25
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    Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.

    Published in:
    Nature Genetics, 2009, v. 41, n. 1, p. 35, doi. 10.1038/ng.271
    By:
    • Sabatti, Chiara;
    • Service, Susan K.;
    • Hartikainen, Anna-Liisa;
    • Pouta, Anneli;
    • Ripatti, Samuli;
    • Brodsky, Jae;
    • Jones, Chris G.;
    • Zaitlen, Noah A.;
    • Varilo, Teppo;
    • Kaakinen, Marika;
    • Sovio, Ulla;
    • Ruokonen, Aimo;
    • Laitinen, Jaana;
    • Jakkula, Eveliina;
    • Coin, Lachlan;
    • Hoggart, Clive;
    • Collins, Andrew;
    • Turunen, Hannu;
    • Gabriel, Stacey;
    • Elliot, Paul
    Publication type:
    Article
    27

    Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.

    Published in:
    Nature Genetics, 2009, v. 41, n. 1, p. 47, doi. 10.1038/ng.269
    By:
    • Aulchenko, Yurii S.;
    • Ripatti, Samuli;
    • Lindqvist, Ida;
    • Boomsma, Dorret;
    • Heid, Iris M.;
    • Pramstaller, Peter P.;
    • Penninx, Brenda W. J. H.;
    • Janssens, A. Cecile J. W.;
    • Wilson, James F.;
    • Spector, Tim;
    • Martin, Nicholas G.;
    • Pedersen, Nancy L.;
    • Kyvik, Kirsten Ohm;
    • Kaprio, Jaakko;
    • Hofman, Albert;
    • Freimer, Nelson B.;
    • Jarvelin, Marjo-Riitta;
    • Gyllensten, Ulf;
    • Campbell, Harry;
    • Rudan, Igor
    Publication type:
    Article
    28
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    Chromosome X-Wide Association Study Identifies Loci for Fasting Insulin and Height and Evidence for Incomplete Dosage Compensation.

    Published in:
    PLoS Genetics, 2014, v. 10, n. 2, p. 1, doi. 10.1371/journal.pgen.1004127
    By:
    • Tukiainen, Taru;
    • Pirinen, Matti;
    • Sarin, Antti-Pekka;
    • Ladenvall, Claes;
    • Kettunen, Johannes;
    • Lehtimäki, Terho;
    • Lokki, Marja-Liisa;
    • Perola, Markus;
    • Sinisalo, Juha;
    • Vlachopoulou, Efthymia;
    • Eriksson, Johan G.;
    • Groop, Leif;
    • Jula, Antti;
    • Järvelin, Marjo-Riitta;
    • Raitakari, Olli T.;
    • Salomaa, Veikko;
    • Ripatti, Samuli
    Publication type:
    Article
    30

    Novel Loci for Metabolic Networks and Multi-Tissue Expression Studies Reveal Genes for Atherosclerosis.

    Published in:
    PLoS Genetics, 2012, v. 8, n. 8, p. 1, doi. 10.1371/journal.pgen.1002907
    By:
    • Inouye, Michael;
    • Ripatti, Samuli;
    • Kettunen, Johannes;
    • Lyytikäinen, Leo-Pekka;
    • Oksala, Niku;
    • Laurila, Pirkka-Pekka;
    • Kangas, Antti J.;
    • Soininen, Pasi;
    • Savolainen, Markku J.;
    • Viikari, Jorma;
    • Kähönen, Mika;
    • Perola, Markus;
    • Salomaa, Veikko;
    • Raitakari, Olli;
    • Lehtimäki, Terho;
    • Taskinen, Marja-Riitta;
    • Järvelin, Marjo-Riitta;
    • Ala-Korpela, Mika;
    • Palotie, Aarno;
    • De Bakker, Paul I. W.
    Publication type:
    Article
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    Biomarker Profiling by Nuclear Magnetic Resonance Spectroscopy for the Prediction of All-Cause Mortality: An Observational Study of 17,345 Persons.

    Published in:
    PLoS Medicine, 2014, v. 11, n. 2, p. 1, doi. 10.1371/journal.pmed.1001606
    By:
    • Fischer, Krista;
    • Kettunen, Johannes;
    • Würtz, Peter;
    • Haller, Toomas;
    • Havulinna, Aki S.;
    • Kangas, Antti J.;
    • Soininen, Pasi;
    • Esko, Tõnu;
    • Tammesoo, Mari-Liis;
    • Mägi, Reedik;
    • Smit, Steven;
    • Palotie, Aarno;
    • Ripatti, Samuli;
    • Salomaa, Veikko;
    • Ala-Korpela, Mika;
    • Perola, Markus;
    • Metspalu, Andres
    Publication type:
    Article
    34
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    The Role of Inflammatory Cytokines as Intermediates in the Pathway from Increased Adiposity to Disease.

    Published in:
    2021
    By:
    • Kalaoja, Marita;
    • Corbin, Laura J.;
    • Tan, Vanessa Y.;
    • Ahola‐Olli, Ari V.;
    • Havulinna, Aki S.;
    • Santalahti, Kristiina;
    • Pitkänen, Niina;
    • Lehtimäki, Terho;
    • Lyytikäinen, Leo‐Pekka;
    • Raitoharju, Emma;
    • Seppälä, Ilkka;
    • Kähönen, Mika;
    • Ripatti, Samuli;
    • Palotie, Aarno;
    • Perola, Markus;
    • Viikari, Jorma S.;
    • Jalkanen, Sirpa;
    • Maksimow, Mikael;
    • Salomaa, Veikko;
    • Salmi, Marko
    Publication type:
    journal article
    36
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    Coronary Artery Disease Risk and Lipidomic Profiles Are Similar in Hyperlipidemias With Family History and Population-Ascertained Hyperlipidemias.

    Published in:
    2019
    By:
    • Rämö, Joel T.;
    • Ripatti, Pietari;
    • Tabassum, Rubina;
    • Söderlund, Sanni;
    • Matikainen, Niina;
    • Gerl, Mathias J.;
    • Klose, Christian;
    • Surma, Michal A.;
    • Stitziel, Nathan O.;
    • Havulinna, Aki S.;
    • Pirinen, Matti;
    • Salomaa, Veikko;
    • Freimer, Nelson B.;
    • Jauhiainen, Matti;
    • Palotie, Aarno;
    • Taskinen, Marja-Riitta;
    • Simons, Kai;
    • Ripatti, Samuli
    Publication type:
    journal article
    38

    Pharmacogenomics of hypertension: a genome‐wide, placebo‐controlled cross‐over study, using four classes of antihypertensive drugs.

    Published in:
    2015
    By:
    • Keaney, John F.;
    • Loscalzo, Joseph;
    • Hiltunen, Timo P;
    • Donner, Kati M;
    • Sarin, Antti-Pekka;
    • Saarela, Janna;
    • Ripatti, Samuli;
    • Chapman, Arlene B;
    • Gums, John G;
    • Gong, Yan;
    • Cooper-DeHoff, Rhonda M;
    • Frau, Francesca;
    • Glorioso, Valeria;
    • Zaninello, Roberta;
    • Salvi, Erika;
    • Glorioso, Nicola;
    • Boerwinkle, Eric;
    • Turner, Stephen T;
    • Johnson, Julie A;
    • Kontula, Kimmo K
    Publication type:
    journal article
    39

    Pharmacogenomics of Hypertension: A Genome-Wide, Placebo-Controlled Cross-Over Study, Using Four Classes of Antihypertensive Drugs.

    Published in:
    Journal of the American Heart Association, 2015, v. 4, n. 1, p. 1, doi. 10.1161/JAHA.114.001521
    By:
    • Hiltunen, Timo P.;
    • Donner, Kati M.;
    • Sarin, Antti‐Pekka;
    • Saarela, Janna;
    • Ripatti, Samuli;
    • Chapman, Arlene B.;
    • Gums, John G.;
    • Gong, Yan;
    • Cooper‐DeHoff, Rhonda M.;
    • Frau, Francesca;
    • Glorioso, Valeria;
    • Zaninello, Roberta;
    • Salvi, Erika;
    • Glorioso, Nicola;
    • Boerwinkle, Eric;
    • Turner, Stephen T.;
    • Johnson, Julie A.;
    • Kontula, Kimmo K.
    Publication type:
    Article
    40

    Genomic prediction of alcohol-related morbidity and mortality.

    Published in:
    Translational Psychiatry, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41398-019-0676-2
    By:
    • Kiiskinen, Tuomo;
    • Mars, Nina J.;
    • Palviainen, Teemu;
    • Koskela, Jukka;
    • Rämö, Joel T.;
    • Ripatti, Pietari;
    • Ruotsalainen, Sanni;
    • Palotie, Aarno;
    • Madden, Pamela A. F.;
    • Rose, Richard J.;
    • Kaprio, Jaakko;
    • Salomaa, Veikko;
    • Mäkelä, Pia;
    • Havulinna, Aki S.;
    • Ripatti, Samuli
    Publication type:
    Article
    41

    Fine-Scale Genetic Structure in Finland.

    Published in:
    G3: Genes | Genomes | Genetics, 2017, v. 7, n. 10, p. 3459, doi. 10.1534/g3.117.300217
    By:
    • Kerminen, Sini;
    • Havulinna, Aki S.;
    • Hellenthal, Garrett;
    • Martin, Alicia R.;
    • Sarin, Antti-Pekka;
    • Perola, Markus;
    • Palotie, Aarno;
    • Salomaa, Veikko;
    • Daly, Mark J.;
    • Ripatti, Samuli;
    • Pirinen, Matti
    Publication type:
    Article
    42
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    Genome-Wide Meta-Analysis of Sciatica in Finnish Population.

    Published in:
    PLoS ONE, 2016, v. 11, n. 10, p. 1, doi. 10.1371/journal.pone.0163877
    By:
    • Lemmelä, Susanna;
    • Solovieva, Svetlana;
    • Shiri, Rahman;
    • Benner, Christian;
    • Heliövaara, Markku;
    • Kettunen, Johannes;
    • Anttila, Verneri;
    • Ripatti, Samuli;
    • Perola, Markus;
    • Seppälä, Ilkka;
    • Juonala, Markus;
    • Kähönen, Mika;
    • Salomaa, Veikko;
    • Viikari, Jorma;
    • Raitakari, Olli T.;
    • Lehtimäki, Terho;
    • Palotie, Aarno;
    • Viikari-Juntura, Eira;
    • Husgafvel-Pursiainen, Kirsti
    Publication type:
    Article
    45
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    Coding haplotype analysis supportsHCR as the putative susceptibility gene for psoriasis at the MHC PSORS1locus.

    Published in:
    Human Molecular Genetics, 2002, v. 11, n. 5, p. 589, doi. 10.1093/hmg/11.5.589
    By:
    • Asumalahti, Kati;
    • Veal, Colin;
    • Laitinen, Tarja;
    • Suomela, Sari;
    • Allen, Michael;
    • Elomaa, Outi;
    • Moser, Michael;
    • deCid, Rafael;
    • Ripatti, Samuli;
    • Vorechovsky, Igor;
    • Marcusson, Jan A.;
    • Nakagawa, Hidemi;
    • Lazaro, Conxi;
    • Estivill, Xavier;
    • Capon, Francesca;
    • Novelli, Giuseppe;
    • The Psoriasis Consortium;
    • Saarialho-Kere, Ulpu;
    • Barker, Jonathan;
    • Trembath, Richard
    Publication type:
    Article
    50

    Inflammatory and infectious upper respiratory diseases associate with 41 genomic loci and type 2 inflammation.

    Published in:
    Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-022-33626-w
    By:
    • Saarentaus, Elmo C.;
    • Karjalainen, Juha;
    • Rämö, Joel T.;
    • Kiiskinen, Tuomo;
    • Havulinna, Aki S.;
    • Mehtonen, Juha;
    • Hautakangas, Heidi;
    • Ruotsalainen, Sanni;
    • Tamlander, Max;
    • Mars, Nina;
    • Toppila-Salmi, Sanna;
    • Pirinen, Matti;
    • Kurki, Mitja;
    • Ripatti, Samuli;
    • Daly, Mark;
    • Palotie, Tuula;
    • Mäkitie, Antti;
    • Palotie, Aarno
    Publication type:
    Article