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Distinct profiles of LRRK2 activation and Rab GTPase phosphorylation in clinical samples from different PD cohorts.
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- NPJ Parkinson's Disease, 2022, v. 8, n. 1, p. 1, doi. 10.1038/s41531-022-00336-5
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- Article
Mechanisms of Caspase-Independent Neuronal Death: Energy Depletion and Free Radical Generation.
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- Journal of Neuroscience, 2003, v. 23, n. 35, p. 11015, doi. 10.1523/JNEUROSCI.23-35-11015.2003
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- Article
Kinase activity of mutant LRRK2 manifests differently in hetero-dimeric vs. homo-dimeric complexes.
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- Biochemical Journal, 2019, v. 476, n. 3, p. 559, doi. 10.1042/BCJ20180589
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- Article
Leucine rich repeat kinase 2 (LRRK2) peptide modulators: Recent advances and future directions.
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- Peptide Science, 2022, v. 114, n. 1, p. 1, doi. 10.1002/pep2.24251
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- Article
The WD40 Domain Is Required for LRRK2 Neurotoxicity.
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- PLoS ONE, 2009, v. 4, n. 12, p. 1, doi. 10.1371/journal.pone.0008463
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- Article
The Future of Targeted Gene-Based Treatment Strategies and Biomarkers in Parkinson's Disease.
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- Biomolecules (2218-273X), 2020, v. 10, n. 6, p. 912, doi. 10.3390/biom10060912
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- Article
The Current State-of-the Art of LRRK2-Based Biomarker Assay Development in Parkinson's Disease.
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- Frontiers in Neuroscience, 2020, p. N.PAG, doi. 10.3389/fnins.2020.00865
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- Article
The Parkinson Disease Protein Leucine-Rich Repeat Kinase 2 Transduces Death Signals via Fas-Associated Protein with Death Domain and Caspase-8 in a Cellular Model of Neurodegeneration.
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- Journal of Neuroscience, 2009, v. 29, n. 4, p. 1011, doi. 10.1523/JNEUROSCI.5175-08.2009
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- Article
Proteasome inhibition and Parkinson's disease modeling.
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- Annals of Neurology, 2006, v. 60, n. 2, p. 260
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- Article
Targeted disruption of neuronal 19S proteasome subunits induces the formation of ubiquitinated inclusions in the absence of cell death.
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- Journal of Neurochemistry, 2011, v. 119, n. 3, p. 630, doi. 10.1111/j.1471-4159.2011.07444.x
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- Article
LRRK2 Parkinson disease mutations enhance its microtubule association.
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- Human Molecular Genetics, 2012, v. 21, n. 4, p. 890, doi. 10.1093/hmg/ddr526
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- Article
Activation of FADD-Dependent Neuronal Death Pathways as a Predictor of Pathogenicity for LRRK2 Mutations.
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- PLoS ONE, 2016, v. 11, n. 11, p. 1, doi. 10.1371/journal.pone.0166053
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- Article
Neuronal death signaling pathways triggered by mutant LRRK2.
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- Biochemical Society Transactions, 2017, v. 45, n. 1, p. 123, doi. 10.1042/BST20160256
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- Article
Elevated In Vitro Kinase Activity in Peripheral Blood Mononuclear Cells of Leucine‐Rich Repeat Kinase 2 G2019S Carriers: A Novel Enzyme‐Linked Immunosorbent Assay–Based Method.
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- Movement Disorders, 2020, v. 35, n. 11, p. 2095, doi. 10.1002/mds.28175
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- Article
Longitudinal transcriptomic analysis of mouse sciatic nerve reveals pathways associated with age‐related muscle pathology.
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- Journal of Cachexia, Sarcopenia & Muscle, 2023, v. 14, n. 3, p. 1322, doi. 10.1002/jcsm.13204
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- Article
A novel cell death pathway that is partially caspase dependent, but morphologically non-apoptotic, elicited by proteasomal inhibition of rat sympathetic neurons.
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- Journal of Neurochemistry, 2008, v. 105, n. 3, p. 653, doi. 10.1111/j.1471-4159.2007.05165.x
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- Article
Differential effects of Parkin and its mutants on protein aggregation, the ubiquitin-proteasome system, and neuronal cell death in human neuroblastoma cells.
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- Journal of Neurochemistry, 2007, v. 102, n. 4, p. 1292, doi. 10.1111/j.1471-4159.2007.04620.x
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- Article
Dopaminergic neurons in rat ventral midbrain cultures undergo selective apoptosis and form inclusions, but do not up-regulate iHSP70, following proteasomal inhibition.
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- Journal of Neurochemistry, 2005, v. 93, n. 5, p. 1304, doi. 10.1111/j.1471-4159.2005.03124.x
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- Article
Application of proteasomal inhibitors to mouse sympathetic neurons activates the intrinsic apoptotic pathway.
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- Journal of Neurochemistry, 2004, v. 90, n. 6, p. 1511, doi. 10.1111/j.1471-4159.2004.02684.x
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- Article
Regulation of α-synuclein by bFGF in cultured ventral midbrain dopaminergic neurons.
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- Journal of Neurochemistry, 2003, v. 84, n. 4, p. 803, doi. 10.1046/j.1471-4159.2003.01574.x
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- Article