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A chimeric antigen receptor-based cellular safeguard mechanism for selective in vivo depletion of engineered T cells.
- Published in:
- Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2023.1268698
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- Article
Metabolic regulation by PD-1 signaling promotes long-lived quiescent CD8 T cell memory in mice.
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- Science Translational Medicine, 2021, v. 13, n. 615, p. 1, doi. 10.1126/scitranslmed.aba6006
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- Article
Comparative analysis of TCR and CAR signaling informs CAR designs with superior antigen sensitivity and in vivo function.
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- Science Signaling, 2021, v. 14, n. 697, p. 1, doi. 10.1126/scisignal.abe2606
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- Article
Phosphoproteomic analysis of chimeric antigen receptor signaling reveals kinetic and quantitative differences that affect cell function.
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- Science Signaling, 2018, v. 11, n. 544, p. 1, doi. 10.1126/scisignal.aat6753
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- Publication type:
- Article
T cell therapy of human CMV and EBV infection in immunocompromised hosts.
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- Reviews in Medical Virology, 1997, v. 7, n. 3, p. 181, doi. 10.1002/(SICI)1099-1654(199709)7:3<181::AID-RMV200>3.0.CO;2-W
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- Article
HLA Engineering of Human Pluripotent Stem Cells.
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- Molecular Therapy, 2013, v. 21, n. 6, p. 1232, doi. 10.1038/mt.2013.59
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- Publication type:
- Article
Immune Responses to AAV in Canine Muscle Monitored by Cellular Assays and Noninvasive Imaging.
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- Molecular Therapy, 2010, v. 18, n. 3, p. 617, doi. 10.1038/mt.2009.294
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- Article
53. Preliminary Results of a Pilot Phase I Clinical Trial of Adoptive Immunotherapy for B Cell Lymphoma Using CD8+ T Cells Genetically Modified To Express a Chimeric T Cell Receptor Recognizing CD20.
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- Molecular Therapy, 2006, v. 13, p. S22, doi. 10.1016/j.ymthe.2006.08.068
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- Publication type:
- Article
Clonal kinetics and single-cell transcriptional profiling of CAR-T cells in patients undergoing CD19 CAR-T immunotherapy.
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- Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-019-13880-1
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- Article
Association between immune recovery uveitis and a diverse intraocular cytomegalovirus-specific cytotoxic T cell response.
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- 2002
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- Publication type:
- journal article
High Frequency of Cytomegalovirus-Specific Cytotoxic T-Effector Cells in HLA-A*0201-Positive...
- Published in:
- Journal of Infectious Diseases, 2000, v. 181, n. 1, p. 165, doi. 10.1086/315201
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- Article
Disseminated intravascular coagulation in lupus erythematosus responding to prednisone therapy.
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- American Journal of Hematology, 1986, v. 23, n. 1, p. 65, doi. 10.1002/ajh.2830230110
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- Article
Immunologic Predictors of Late Cytomegalovirus Disease after Solid Organ Transplantation--An Elusive Goal?
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- Journal of Infectious Diseases, 2007, v. 195, n. 5, p. 615, doi. 10.1086/511311
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- Publication type:
- Article
Costimulation of CD8αβ T cells by NKG2D via engagement by MIC induced on virus-infected cells.
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- Nature Immunology, 2001, v. 2, n. 3, p. 255, doi. 10.1038/85321
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- Article
Exploiting T cells specific for human minor histocompatibility antigens for therapy of leukemia.
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- Immunology & Cell Biology, 2011, v. 89, n. 3, p. 396, doi. 10.1038/icb.2010.124
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- Article
Cytomegalovirus US2 destroys two components of the MHC class II pathway, preventing recognition by CD4<sup>+</sup> T cells.
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- Nature Medicine, 1999, v. 5, n. 9, p. 1039, doi. 10.1038/12478
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- Publication type:
- Article
In vivo migration and function of transferred HIV-1-specific cytotoxic T cells.
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- Nature Medicine, 1999, v. 5, n. 1, p. 34, doi. 10.1038/4716
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- Publication type:
- Article
Identification of MAGE-C1 (CT-7) epitopes for T-cell therapy of multiple myeloma.
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- Cancer Immunology, Immunotherapy, 2011, v. 60, n. 7, p. 985, doi. 10.1007/s00262-011-1009-3
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- Publication type:
- Article
Molecules and mechanisms of the graft-versus-leukaemia effect.
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- Nature Reviews Cancer, 2004, v. 4, n. 5, p. 371, doi. 10.1038/nrc1365
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- Publication type:
- Article
Human cytomegalovirus microRNA miR-US4-1 inhibits CD8<sup>+</sup> T cell responses by targeting the aminopeptidase ERAP1.
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- Nature Immunology, 2011, v. 12, n. 10, p. 984, doi. 10.1038/ni.2097
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- Article
A therapeutic cancer vaccine delivers antigens and adjuvants to lymphoid tissues using genetically modified T cells.
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- 2021
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- Publication type:
- journal article
Cytomegalovirus selectivity blocks antigen processing and presentation of its immediate-early...
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- Nature, 1996, v. 383, n. 6602, p. 720, doi. 10.1038/383720a0
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- Publication type:
- Article
Tumor-Specific T-Cell Immunity: Ready for Prime Time?
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- JNCI: Journal of the National Cancer Institute, 1992, v. 84, n. 14, p. 1059
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- Article
Pancreatic Ductal Adenocarcinoma Contains an Effector and Regulatory Immune Cell Infiltrate that Is Altered by Multimodal Neoadjuvant Treatment.
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- PLoS ONE, 2014, v. 9, n. 5, p. 1, doi. 10.1371/journal.pone.0096565
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- Article
Combining a CD20 Chimeric Antigen Receptor and an Inducible Caspase 9 Suicide Switch to Improve the Efficacy and Safety of T Cell Adoptive Immunotherapy for Lymphoma.
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- PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0082742
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- Publication type:
- Article
Proliferation-Linked Apoptosis of Adoptively Transferred T Cells after IL-15 Administration in Macaques.
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- PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0056268
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- Article
Novel Serial Positive Enrichment Technology Enables Clinical Multiparameter Cell Sorting.
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- PLoS ONE, 2012, v. 7, n. 4, p. 1, doi. 10.1371/journal.pone.0035798
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- Publication type:
- Article
A split, conditionally active mimetic of IL-2 reduces the toxicity of systemic cytokine therapy.
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- Nature Biotechnology, 2023, v. 41, n. 4, p. 532, doi. 10.1038/s41587-022-01510-z
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- Article
Minor histocompatibility antigens--targets of graft versus leukemia responses.
- Published in:
- 2002
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- Publication type:
- journal article
Cellular Immunotherapy for Follicular Lymphoma Using Genetically Modified CD20-Specific CD8<sup>+</sup> Cytotoxic T Lymphocytes
- Published in:
- Molecular Therapy, 2004, v. 9, n. 4, p. 577, doi. 10.1016/j.ymthe.2003.12.011
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- Article
TIM-3<sup>+</sup> CD8 T cells with a terminally exhausted phenotype retain functional capacity in hematological malignancies.
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- Science Immunology, 2024, v. 9, n. 94, p. 1, doi. 10.1126/sciimmunol.adg1094
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- Publication type:
- Article
Immunotherapy of non-Hodgkin’s lymphoma with a defined ratio of CD8<sup>+</sup> and CD4<sup>+</sup> CD19-specific chimeric antigen receptor–modified T cells.
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- Science Translational Medicine, 2016, v. 8, n. 355, p. 1, doi. 10.1126/scitranslmed.aaf8621
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- Article
Adoptive cellular therapy: A race to the finish line.
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- Science Translational Medicine, 2015, v. 7, n. 280, p. 1, doi. 10.1126/scitranslmed.aaa3643
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- Article
TCR-Ligand k<sub>off</sub> Rate Correlates with the Protective Capacity of Antigen-Specific CD8<sup>+</sup>T Cells for Adoptive Transfer.
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- Science Translational Medicine, 2013, v. 5, n. 192, p. 1, doi. 10.1126/scitranslmed.3005958
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- Article
Graft-Versus-Host Disease: A Surge of Developments.
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- PLoS Medicine, 2007, v. 4, n. 7, p. e198, doi. 10.1371/journal.pmed.0040198
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- Article
Identification of the major late human cytomegalovirus matrix protein pp65 as a target antigen for CD8<sup>+</sup> virus-specific cytotoxic T lymphocytes.
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- Journal of Medical Virology, 1994, v. 43, n. 1, p. 103, doi. 10.1002/jmv.1890430119
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- Article
CARs derived from broadly neutralizing, human monoclonal antibodies identified by single B cell sorting target hepatitis B virus-positive cells.
- Published in:
- Frontiers in Immunology, 2024, p. 01, doi. 10.3389/fimmu.2024.1340619
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- Article
Overlap and Effective Size of the Human CD8<sup>+</sup> T Cell Receptor Repertoire.
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- Science Translational Medicine, 2010, v. 2, n. 47, p. 1, doi. 10.1126/scitranslmed.3001442
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- Article
Design and implementation of adoptive therapy with chimeric antigen receptor-modified T cells.
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- Immunological Reviews, 2014, v. 257, n. 1, p. 127, doi. 10.1111/imr.12139
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- Article
Inclusion of Strep-tag II in design of antigen receptors for T-cell immunotherapy.
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- Nature Biotechnology, 2016, v. 34, n. 4, p. 430, doi. 10.1038/nbt.3461
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- Article
A BiTE from cancer's intracellular menu.
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- Nature Biotechnology, 2015, v. 33, n. 10, p. 1040, doi. 10.1038/nbt.3370
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- Article
Tumor-infiltrating BRAFV600E-specific CD4+ T cells correlated with complete clinical response in melanoma.
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- 2018
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- Publication type:
- journal article
Targeted antibody-mediated depletion of murine CD19 CAR T cells permanently reverses B cell aplasia.
- Published in:
- 2016
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- Publication type:
- journal article
Outcomes of acute leukemia patients transplanted with naive T cell-depleted stem cell grafts.
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- Journal of Clinical Investigation, 2015, v. 125, n. 7, p. 2677, doi. 10.1172/JCI81229
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- Article
The emperor of all maladies.
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- 2011
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- Book Review
Adoptive transfer of effector CD8+ T cells derived from central memory cells establishes persistent T cell memory in primates.
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- 2008
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- Publication type:
- journal article
Proteolytically generated soluble Tweak Receptor Fn14 is a blood biomarker for γ‐secretase activity.
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- EMBO Molecular Medicine, 2022, v. 14, n. 10, p. 1, doi. 10.15252/emmm.202216084
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- Article
A UGT2B17-positive donor is a risk factor for higher transplant-related mortality and lower survival after bone marrow transplantation.
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- British Journal of Haematology, 2005, v. 129, n. 2, p. 221, doi. 10.1111/j.1365-2141.2005.05427.x
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- Publication type:
- Article
Disparity for a newly identified minor histocompatibility antigen, HA-8, correlates with acute graft- versus-host disease after haematopoietic stem cell transplantation from an HLA-identical sibling.
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- British Journal of Haematology, 2003, v. 123, n. 4, p. 671, doi. 10.1046/j.1365-2141.2003.04676.x
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- Article