Works matching AU Ricklin, Daniel

Results: 47

Complement: a key system for immune surveillance and homeostasis.

Published in:

Nature Immunology, 2010, v. 11, n. 9, p. 785, doi. 10.1038/ni.1923

By:

Ricklin, Daniel;
Hajishengallis, George;
Kun Yang;
Lambris, John D.

Publication type:

Article

Structural and functional implications of the alternative complement pathway C3 convertase stabilized by a staphylococcal inhibitor.

Published in:

Nature Immunology, 2009, v. 10, n. 7, p. 721, doi. 10.1038/ni.1756

By:

Rooijakkers, Suzan H. M.;
Jin Wu;
Ruyken, Maartje;
van Domselaar, Robert;
Planken, Karel L.;
Tzekou, Apostolia;
Ricklin, Daniel;
Lambris, John D.;
Janssen, Bert J. C.;
van Strijp, Jos A. G.;
Gros, Piet

Publication type:

Article

Structure of complement fragment C3b–factor H and implications for host protection by complement regulators.

Published in:

Nature Immunology, 2009, v. 10, n. 7, p. 728, doi. 10.1038/ni.1755

By:

Jin Wu;
You-Qiang Wu;
Ricklin, Daniel;
Janssen, Bert J. C.;
Lambris, John D.;
Gros, Piet

Publication type:

Article

A structural basis for complement inhibition by Staphylococcus aureus.

Published in:

Nature Immunology, 2007, v. 8, n. 4, p. 430, doi. 10.1038/ni1450

By:

Hammel, Michal;
Sfyroera, Georgia;
Ricklin, Daniel;
Magotti, Paola;
Lambris, John D;
Geisbrecht, Brian V

Publication type:

Article

Complement inhibition can decrease the haemostatic response in a microvascular bleeding model at multiple levels.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1226832

By:

Golomingi, Murielle;
Kohler, Jessie;
Lamers, Christina;
Pouw, Richard B.;
Ricklin, Daniel;
Dobó, József;
Gál, Péter;
Pál, Gábor;
Kiss, Bence;
Dopler, Arthur;
Schmidt, Christoph Q.;
Hardy, Elaissa Trybus;
Lam, Wilbur;
Schroeder, Verena

Publication type:

Article

Structure-kinetic relationship analysis of the therapeutic complement inhibitor compstatin.

Published in:

Journal of Molecular Recognition, 2009, v. 22, n. 6, p. 495, doi. 10.1002/jmr.972

By:

Magotti, Paola;
Ricklin, Daniel;
Qu, Hongchang;
Wu, You-Qiang;
Kaznessis, Yiannis N.;
Lambris, John D.

Publication type:

Article

Oligohis-tags: mechanisms of binding to Ni.

Published in:

Journal of Molecular Recognition, 2009, v. 22, n. 4, p. 270, doi. 10.1002/jmr.941

By:

Knecht, Steven;
Ricklin, Daniel;
Eberle, Alex N.;
Ernst, Beat

Publication type:

Article

Complement evasion by human pathogens.

Published in:

Nature Reviews Microbiology, 2008, v. 6, n. 2, p. 132, doi. 10.1038/nrmicro1824

By:

Lambris, John D.;
Ricklin, Daniel;
Geisbrecht, Brian V.

Publication type:

Article

Tetra‐ and Hexavalent Siglec‐8 Ligands Modulate Immune Cell Activation.

Published in:

Angewandte Chemie, 2023, v. 135, n. 52, p. 1, doi. 10.1002/ange.202314280

By:

Conti, Gabriele;
Bärenwaldt, Anne;
Rabbani, Said;
Mühlethaler, Tobias;
Sarcevic, Mirza;
Jiang, Xiaohua;
Schwardt, Oliver;
Ricklin, Daniel;
Pieters, Roland J.;
Läubli, Heinz;
Ernst, Beat

Publication type:

Article

Complement‐targeted therapeutics: An emerging field enabled by academic drug discovery.

Published in:

American Journal of Hematology, 2023, v. 98, p. S82, doi. 10.1002/ajh.26875

By:

Lamers, Christina;
Ricklin, Daniel;
Lambris, John D.

Publication type:

Article

On the functional overlap between complement and anti-microbial peptides.

Published in:

Frontiers in Immunology, 2015, v. 5, p. 1, doi. 10.3389/fimmu.2014.00689

By:

Zimmer, Jana;
Hobkirk, James;
Mohamed, Fatima;
Browning, Michael J.;
Stover, Cordula M.;
Filep, Janos G.;
Ricklin, Daniel

Publication type:

Article

Factor h c-Terminal Domains are critical for regulation of Platelet/granulocyte aggregate Formation.

Published in:

Frontiers in Immunology, 2017, p. 1, doi. 10.3389/fimmu.2017.01586

By:

Blatt, Adam Z.;
Saggu, Gurpanna;
Cortes, Claudio;
Herbert, Andrew P.;
Kavanagh, David;
Ricklin, Daniel;
Lambris, John D.;
Ferreira, Viviana P.

Publication type:

Article

Complement‐targeted therapeutics: Are we there yet, or just getting started?

Published in:

European Journal of Immunology, 2024, v. 54, n. 12, p. 1, doi. 10.1002/eji.202350816

By:

Ricklin, Daniel

Publication type:

Article

Complement in paroxysmal nocturnal hemoglobinuria: exploiting our current knowledge to improve the treatment landscape.

Published in:

Expert Review of Hematology, 2014, v. 7, n. 5, p. 583, doi. 10.1586/17474086.2014.953926

By:

Mastellos, Dimitrios C;
Ricklin, Daniel;
Yancopoulou, Despina;
Risitano, Antonio;
Lambris, John D

Publication type:

Article

Sweet turning bitter: Carbohydrate sensing of complement in host defence and disease.

Published in:

2021

By:

Hevey, Rachel;
Pouw, Richard B.;
Harris, Claire;
Ricklin, Daniel

Publication type:

journal article

Insight into mode-of-action and structural determinants of the compstatin family of clinical complement inhibitors.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-33003-7

By:

Lamers, Christina;
Xue, Xiaoguang;
Smieško, Martin;
van Son, Henri;
Wagner, Bea;
Berger, Nadja;
Sfyroera, Georgia;
Gros, Piet;
Lambris, John D.;
Ricklin, Daniel

Publication type:

Article

Tetra‐ and Hexavalent Siglec‐8 Ligands Modulate Immune Cell Activation.

Published in:

Angewandte Chemie International Edition, 2023, v. 62, n. 52, p. 1, doi. 10.1002/anie.202314280

By:

Conti, Gabriele;
Bärenwaldt, Anne;
Rabbani, Said;
Mühlethaler, Tobias;
Sarcevic, Mirza;
Jiang, Xiaohua;
Schwardt, Oliver;
Ricklin, Daniel;
Pieters, Roland J.;
Läubli, Heinz;
Ernst, Beat

Publication type:

Article

Electrostatic contributions drive the interaction between Staphylococcus aureus protein Efb-C and its complement target C3d.

Published in:

Protein Science: A Publication of the Protein Society, 2008, v. 17, n. 11, p. 1894, doi. 10.1110/ps.036624.108

By:

Haspel, Nurit;
Ricklin, Daniel;
Geisbrecht, Brian V.;
Kavraki, Lydia E.;
Lambris, John D.

Publication type:

Article

Regulators of complement activity mediate inhibitory mechanisms through a common C3b-binding mode.

Published in:

EMBO Journal, 2016, v. 35, n. 10, p. 1133, doi. 10.15252/embj.201593673

By:

Forneris, Federico;
Wu, Jin;
Xue, Xiaoguang;
Ricklin, Daniel;
Lin, Zhuoer;
Sfyroera, Georgia;
Tzekou, Apostolia;
Volokhina, Elena;
Granneman, Joke CM;
Hauhart, Richard;
Bertram, Paula;
Liszewski, M Kathryn;
Atkinson, John P;
Lambris, John D;
Gros, Piet

Publication type:

Article

CMAP: Complement Map Database.

Published in:

Bioinformatics, 2013, v. 29, n. 14, p. 1832, doi. 10.1093/bioinformatics/btt269

By:

Yang, Kun;
Dinasarapu, Ashok R.;
Reis, Edimara S.;
DeAngelis, Robert A.;
Ricklin, Daniel;
Subramaniam, Shankar;
Lambris, John D.

Publication type:

Article

Therapeutic Peptides as Emerging Options to Restore Misguided Host Defence and Homeostasis: From Teaching to Concept to Clinic.

Published in:

Chimia, 2021, v. 75, n. 6, p. 495, doi. 10.2533/chimia.2021.495

By:

Schwardt, Oliver;
Lamers, Christina;
Bechtler, Clément;
Ricklin, Daniel

Publication type:

Article

Correction to: Characterization of the first fully human anti-TEM1 scFv in models of solid tumor imaging and immunotoxin-based therapy.

Published in:

Cancer Immunology, Immunotherapy, 2018, v. 67, n. 2, p. 329, doi. 10.1007/s00262-017-2101-0

By:

Yuan, Xiaopeng;
Yang, Mingjuan;
Chen, Xiang;
Zhang, Xuhua;
Sukhadia, Shrey;
Musolino, Najia;
Bao, Huijing;
Chen, Tingtao;
Xu, Chen;
Wang, Qirui;
Santoro, Stephen;
Ricklin, Daniel;
Hu, Jia;
Lin, Ruihe;
Yang, Wei;
Li, Zhijun;
Qin, Weijun;
Zhao, Aizhi;
Scholler, Nathalie;
Coukos, George

Publication type:

Article

Characterization of the first fully human anti-TEM1 scFv in models of solid tumor imaging and immunotoxin-based therapy.

Published in:

Cancer Immunology, Immunotherapy, 2017, v. 66, n. 3, p. 367, doi. 10.1007/s00262-016-1937-z

By:

Yuan, Xiaopeng;
Yang, Mingjuan;
Chen, Xiang;
Zhang, Xuhua;
Sukhadia, Shrey;
Musolino, Najia;
Bao, Huijing;
Chen, Tingtao;
Xu, Chen;
Wang, Qirui;
Santoro, Stephen;
Ricklin, Daniel;
Hu, Jia;
Lin, Ruihe;
Yang, Wei;
Li, Zhijun;
Qin, Weijun;
Zhao, Aizhi

Publication type:

Article

Determining Ligand Binding and Specificity Within the β 2 -Integrin Family with a Novel Assay Platform.

Published in:

Biomolecules (2218-273X), 2025, v. 15, n. 2, p. 238, doi. 10.3390/biom15020238

By:

Sommer-Plüss, Carla Johanna;
Leiggener, Céline;
Nikci, Elira;
Mancuso, Riccardo Vincenzo;
Rabbani, Said;
Lamers, Christina;
Ricklin, Daniel

Publication type:

Article

Praziquantel and factor H recruitment differentially affect the susceptibility of Schistosoma mansoni to complement-mediated damage.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1474358

By:

van Beek, Anna E.;
Jeanguenat, Hannah;
Häberli, Cécile;
Pouw, Richard B.;
Lamers, Christina;
Pál, Gábor;
Gál, Péter;
Schmidt, Christoph Q.;
Ricklin, Daniel;
Keiser, Jennifer

Publication type:

Article

Inhibition of pre-existing natural periodontitis in non-human primates by a locally administered peptide inhibitor of complement C3.

Published in:

Journal of Clinical Periodontology, 2016, v. 43, n. 3, p. 238, doi. 10.1111/jcpe.12507

By:

Maekawa, Tomoki;
Briones, Ruel A.;
Resuello, Ranillo R.G.;
Tuplano, Joel V.;
Hajishengallis, Evlambia;
Kajikawa, Tetsuhiro;
Koutsogiannaki, Sophia;
Garcia, Cristina A.G.;
Ricklin, Daniel;
Lambris, John D.;
Hajishengallis, George

Publication type:

Article

Conjugation to Albumin-Binding Molecule Tags as a Strategy to Improve Both Efficacy and Pharmacokinetic Properties of the Complement Inhibitor Compstatin.

Published in:

ChemMedChem, 2014, v. 9, n. 10, p. 2223, doi. 10.1002/cmdc.201402212

By:

Huang, Yijun;
Reis, Edimara S.;
Knerr, Patrick J.;
van der Donk, Wilfred A.;
Ricklin, Daniel;
Lambris, John D.

Publication type:

Article

Cover Picture: Conjugation to Albumin-Binding Molecule Tags as a Strategy to Improve Both Efficacy and Pharmacokinetic Properties of the Complement Inhibitor Compstatin (ChemMedChem 10/2014).

Published in:

ChemMedChem, 2014, v. 9, n. 10, p. 2209, doi. 10.1002/cmdc.201490037

By:

Huang, Yijun;
Reis, Edimara S.;
Knerr, Patrick J.;
van der Donk, Wilfred A.;
Ricklin, Daniel;
Lambris, John D.

Publication type:

Article

Protection of host cells by complement regulators.

Published in:

Immunological Reviews, 2016, v. 274, n. 1, p. 152, doi. 10.1111/imr.12475

By:

Schmidt, Christoph Q.;
Lambris, John D.;
Ricklin, Daniel

Publication type:

Article

Preformed mediators of defense-Gatekeepers enter the spotlight.

Published in:

Immunological Reviews, 2016, v. 274, n. 1, p. 5, doi. 10.1111/imr.12497

By:

Ricklin, Daniel;
Lambris, John D.

Publication type:

Article

Complement component C3 - The 'Swiss Army Knife' of innate immunity and host defense.

Published in:

Immunological Reviews, 2016, v. 274, n. 1, p. 33, doi. 10.1111/imr.12500

By:

Ricklin, Daniel;
Reis, Edimara S.;
Mastellos, Dimitrios C.;
Gros, Piet;
Lambris, John D.

Publication type:

Article

The Promiscuous Profile of Complement Receptor 3 in Ligand Binding, Immune Modulation, and Pathophysiology.

Published in:

Frontiers in Immunology, 2021, v. 11, p. N.PAG, doi. 10.3389/fimmu.2021.662164

By:

Lamers, Christina;
Plüss, Carla Johanna;
Ricklin, Daniel

Publication type:

Article

Deregulation of Factor H by Factor H-Related Protein 1 Depends on Sialylation of Host Surfaces.

Published in:

Frontiers in Immunology, 2021, v. 11, p. N.PAG, doi. 10.3389/fimmu.2021.615748

By:

Dopler, Arthur;
Stibitzky, Selina;
Hevey, Rachel;
Mannes, Marco;
Guariento, Mara;
Höchsmann, Britta;
Schrezenmeier, Hubert;
Ricklin, Daniel;
Schmidt, Christoph Q.

Publication type:

Article

A sweet spot to control complement-induced inflammation.

Published in:

Nature Medicine, 2012, v. 18, n. 9, p. 1340, doi. 10.1038/nm.2916

By:

Ricklin, Daniel;
Reis, Edimara S;
Lambris, John D

Publication type:

Article

Inhibition of biomaterial-induced complement activation attenuates the inflammatory host response to implantation.

Published in:

FASEB Journal, 2013, v. 27, n. 7, p. 2768, doi. 10.1096/fj.12-225888

By:

Kourtzelis, Ioannis;
Rafail, Stavros;
DeAngelis, Robert A.;
Foukas, Periklis G.;
Ricklin, Daniel;
Lambris, John D.

Publication type:

Article

Contribution of Chondroitin Sulfate A to the Binding of Complement Proteins to Activated Platelets.

Published in:

PLoS ONE, 2010, v. 5, n. 9, p. 1, doi. 10.1371/journal.pone.0012889

By:

Hamad, Osama A.;
Nilsson, Per H.;
Lasaosa, Maria;
Ricklin, Daniel;
Lambris, John D.;
Nilsson, Bo;
Ekdahl, Kristina Nilsson

Publication type:

Article

Compstatin: a C3-targeted complement inhibitor reaching its prime for bedside intervention.

Published in:

European Journal of Clinical Investigation, 2015, v. 45, n. 4, p. 423, doi. 10.1111/eci.12419

By:

Mastellos, Dimitrios C.;
Yancopoulou, Despina;
Kokkinos, Petros;
Huber‐Lang, Markus;
Hajishengallis, George;
Biglarnia, Ali R.;
Lupu, Florea;
Nilsson, Bo;
Risitano, Antonio M.;
Ricklin, Daniel;
Lambris, John D.

Publication type:

Article

Front Cover: Selective Monovalent Galectin‐8 Ligands Based on 3‐Lactoylgalactoside (ChemMedChem 3/2022)

Published in:

ChemMedChem, 2022, v. 17, n. 3, p. 1, doi. 10.1002/cmdc.202200044

By:

Girardi, Benedetta;
Manna, Martina;
Van Klaveren, Sjors;
Tomašič, Tihomir;
Jakopin, Žiga;
Leffler, Hakon;
Nilsson, Ulf J.;
Ricklin, Daniel;
Mravljak, Janez;
Schwardt, Oliver;
Anderluh, Marko

Publication type:

Article

Front Cover: Selective Monovalent Galectin‐8 Ligands Based on 3‐Lactoylgalactoside (ChemMedChem 3/2022).

Published in:

ChemMedChem, 2022, v. 17, n. 3, p. 1, doi. 10.1002/cmdc.202100514

By:

Girardi, Benedetta;
Manna, Martina;
Van Klaveren, Sjors;
Tomašič, Tihomir;
Jakopin, Žiga;
Leffler, Hakon;
Nilsson, Ulf J.;
Ricklin, Daniel;
Mravljak, Janez;
Schwardt, Oliver;
Anderluh, Marko

Publication type:

Article

Selective Monovalent Galectin‐8 Ligands Based on 3‐Lactoylgalactoside.

Published in:

ChemMedChem, 2022, v. 17, n. 3, p. 1, doi. 10.1002/cmdc.202100514

By:

Girardi, Benedetta;
Manna, Martina;
Van Klaveren, Sjors;
Tomašič, Tihomir;
Jakopin, Žiga;
Leffler, Hakon;
Nilsson, Ulf J.;
Ricklin, Daniel;
Mravljak, Janez;
Schwardt, Oliver;
Anderluh, Marko

Publication type:

Article

A Potent Mimetic of the Siglec‐8 Ligand 6'‐Sulfo‐Sialyl Lewis<sup>x</sup>.

Published in:

ChemMedChem, 2020, v. 15, n. 18, p. 1680, doi. 10.1002/cmdc.202000649

By:

Kroezen, Blijke S.;
Conti, Gabriele;
Girardi, Benedetta;
Cramer, Jonathan;
Jiang, Xiaohua;
Rabbani, Said;
Müller, Jennifer;
Kokot, Maja;
Luisoni, Enrico;
Ricklin, Daniel;
Schwardt, Oliver;
Ernst, Beat

Publication type:

Article

A Potent Mimetic of the Siglec‐8 Ligand 6'‐Sulfo‐Sialyl Lewis<sup>x</sup>.

Published in:

ChemMedChem, 2020, v. 15, n. 18, p. 1706, doi. 10.1002/cmdc.202000417

By:

Kroezen, Blijke S.;
Conti, Gabriele;
Girardi, Benedetta;
Cramer, Jonathan;
Jiang, Xiaohua;
Rabbani, Said;
Müller, Jennifer;
Kokot, Maja;
Luisoni, Enrico;
Ricklin, Daniel;
Schwardt, Oliver;
Ernst, Beat

Publication type:

Article

Complement-targeted therapeutics.

Published in:

Nature Biotechnology, 2007, v. 25, n. 11, p. 1265, doi. 10.1038/nbt1342

By:

Ricklin, Daniel;
Lambris, John D.

Publication type:

Article

Tipping the balance: intricate roles of the complement system in disease and therapy.

Published in:

Seminars in Immunopathology, 2021, v. 43, n. 6, p. 757, doi. 10.1007/s00281-021-00892-7

By:

Pouw, Richard B.;
Ricklin, Daniel

Publication type:

Article

Complement & disease: out of the shadow into the spotlight.

Published in:

Seminars in Immunopathology, 2021, v. 43, n. 6, p. 755, doi. 10.1007/s00281-021-00897-2

By:

Ricklin, Daniel;
Pouw, Richard B.

Publication type:

Article

Interactions between coagulation and complement-their role in inflammation.

Published in:

Seminars in Immunopathology, 2012, v. 34, n. 1, p. 151, doi. 10.1007/s00281-011-0280-x

By:

Oikonomopoulou, Katerina;
Ricklin, Daniel;
Ward, Peter;
Lambris, John

Publication type:

Article

Optimized synthesis, polymer conjugation, and proof‐of‐concept studies of the gd‐IgA1 epitope for antibody‐scavenging therapies in IgA nephropathy.

Published in:

Chemical Biology & Drug Design, 2023, v. 102, n. 3, p. 580, doi. 10.1111/cbdd.14258

By:

Bechtler, Clément;
Barneoud‐Rousset, Ouliana;
Pang, Lijuan;
Martin, Kea;
König, Katrin F.;
Hänggi, Pascal;
Pearson, Nick;
Ricklin, Daniel

Publication type:

Article