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Bis-γ-carbolines as new potential multitarget agents for Alzheimer's disease.
- Published in:
- Pure & Applied Chemistry, 2020, v. 92, n. 7, p. 1057, doi. 10.1515/pac-2019-1206
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- Article
Synthesis of 4-Aminopyrazol-5-ols as Edaravone Analogs and Their Antioxidant Activity.
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- Molecules, 2022, v. 27, n. 22, p. 7722, doi. 10.3390/molecules27227722
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- Article
Bis-Amiridines as Acetylcholinesterase and Butyrylcholinesterase Inhibitors: N -Functionalization Determines the Multitarget Anti-Alzheimer's Activity Profile.
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- Molecules, 2022, v. 27, n. 3, p. 1060, doi. 10.3390/molecules27031060
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- Article
Conjugation of Aminoadamantane and γ-Carboline Pharmacophores Gives Rise to Unexpected Properties of Multifunctional Ligands.
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- Molecules, 2021, v. 26, n. 18, p. 5527, doi. 10.3390/molecules26185527
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- Article
Development and Validation of a Chiral Liquid Chromatographic Assay for Enantiomeric Separation and Quantification of Verapamil in Rat Plasma: Stereoselective Pharmacokinetic Application.
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- Molecules, 2021, v. 26, n. 7, p. 2091, doi. 10.3390/molecules26072091
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- Article
Genetically Encodable Scaffolds for Optimizing Enzyme Function.
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- Molecules, 2021, v. 26, n. 5, p. 1389, doi. 10.3390/molecules26051389
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- Article
Identification of Three Small Molecules That Can Selectively Influence Cellular Manganese Levels in a Mouse Striatal Cell Model.
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- Molecules, 2021, v. 26, n. 4, p. 1175, doi. 10.3390/molecules26041175
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- Article
New Multifunctional Agents Based on Conjugates of 4-Amino-2,3-polymethylenequinoline and Butylated Hydroxytoluene for Alzheimer's Disease Treatment.
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- Molecules, 2020, v. 25, n. 24, p. 5891, doi. 10.3390/molecules25245891
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- Article
Protease Inhibitory Effect of Natural Polyphenolic Compounds on SARS-CoV-2: An In Silico Study.
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- Molecules, 2020, v. 25, n. 20, p. 4604, doi. 10.3390/molecules25204604
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- Article
New Hybrids of 4-Amino-2,3-polymethylene-quinoline and p-Tolylsulfonamide as Dual Inhibitors of Acetyl- and Butyrylcholinesterase and Potential Multifunctional Agents for Alzheimer's Disease Treatment.
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- Molecules, 2020, v. 25, n. 17, p. 3915, doi. 10.3390/molecules25173915
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- Article
Super Secondary Structures of Proteins with Post-Translational Modifications in Colon Cancer.
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- Molecules, 2020, v. 25, n. 14, p. 3144, doi. 10.3390/molecules25143144
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- Article
Conjugates of methylene blue with γ-carboline derivatives as new multifunctional agents for the treatment of neurodegenerative diseases.
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- Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-41272-4
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- Article
Conjugates of Tacrine with Salicylamide as Promising Multitarget Agents for Alzheimer's Disease.
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- ChemMedChem, 2022, v. 17, n. 10, p. 1, doi. 10.1002/cmdc.202200080
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- Article
Evaluation of von Willebrand Factor and von Willebrand Factor Propeptide in Models of Vascular Endothelial Cell Activation, Perturbation, and/or Injury.
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- Toxicologic Pathology, 2014, v. 42, n. 4, p. 672, doi. 10.1177/0192623313518664
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- Article
Evidence for the Nitric Oxide Pathway as a Potential Mode of Action in Fenoldopam-induced Vascular Injury.
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- Toxicologic Pathology, 2012, v. 40, n. 6, p. 874, doi. 10.1177/0192623312444027
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- Article
Biomarkers and Mechanisms of Drug-Induced Vascular Injury in Non-Rodents.
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- Toxicologic Pathology, 2006, v. 34, n. 1, p. 19, doi. 10.1080/01926230500512076
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- Article
Conjugates of Tacrine and Salicylic Acid Derivatives as New Promising Multitarget Agents for Alzheimer's Disease.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 3, p. 2285, doi. 10.3390/ijms24032285
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- Article
Conjugates of Methylene Blue with Cycloalkaneindoles as New Multifunctional Agents for Potential Treatment of Neurodegenerative Disease.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 22, p. 13925, doi. 10.3390/ijms232213925
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- Article
Derivatives of 9-phosphorylated acridine as butyrylcholinesterase inhibitors with antioxidant activity and the ability to inhibit β-amyloid self-aggregation: potential therapeutic agents for Alzheimer's disease.
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- Frontiers in Pharmacology, 2023, p. 01, doi. 10.3389/fphar.2023.1219980
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- Article
Biosensor assay of neuropathy target esterase in whole blood as a new approach to OPIDN risk assessment: review of progress.
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- Human & Experimental Toxicology, 2007, v. 26, n. 4, p. 273, doi. 10.1177/0960327106070463
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- Article
Crystal Structure of Patatin-17 in Complex with Aged and Non-Aged Organophosphorus Compounds.
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- PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0108245
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- Article
New Multifunctional Agents for Potential Alzheimer's Disease Treatment Based on Tacrine Conjugates with 2-Arylhydrazinylidene-1,3-Diketones.
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- Biomolecules (2218-273X), 2022, v. 12, n. 11, p. 1551, doi. 10.3390/biom12111551
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- Article
Combining Experimental and Computational Methods to Produce Conjugates of Anticholinesterase and Antioxidant Pharmacophores with Linker Chemistries Affecting Biological Activities Related to Treatment of Alzheimer's Disease.
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- Molecules, 2024, v. 29, n. 2, p. 321, doi. 10.3390/molecules29020321
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- Article
Neuropathy target esterase in mouse whole blood as a biomarker of exposure to neuropathic organophosphorus compounds.
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- Journal of Applied Toxicology, 2016, v. 36, n. 11, p. 1468, doi. 10.1002/jat.3305
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Further studies toward a mouse model for biochemical assessment of neuropathic potential of organophosphorus compounds.
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- Journal of Applied Toxicology, 2014, v. 34, n. 12, p. 1426, doi. 10.1002/jat.2977
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- Article
Metabolites of n-Butylparaben and iso-Butylparaben Exhibit Estrogenic Properties in MCF-7 and T47D Human Breast Cancer Cell Lines.
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- Toxicological Sciences, 2018, v. 164, n. 1, p. 50, doi. 10.1093/toxsci/kfy063
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- Article
Mixed Inhibition of Adenosine Deaminase Activity by 1,3-Dinitrobenzene: A Model for Understanding Cell-Selective Neurotoxicity in Chemically-Induced Energy Deprivation Syndromes in Brain.
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- Toxicological Sciences, 2012, v. 125, n. 2, p. 509, doi. 10.1093/toxsci/kfr317
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- Article
Dose-Effect Analyses of Occupational Chlorpyrifos Exposure and Peripheral Nerve Electrophysiology.
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- Toxicological Sciences, 2007, v. 97, n. 1, p. 196, doi. 10.1093/toxsci/kfm028
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- Article
Motor neuron disease due to neuropathy target esterase gene mutation: Clinical features of the index families.
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- Muscle & Nerve, 2011, v. 43, n. 1, p. 19, doi. 10.1002/mus.21777
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- Article
Paraoxonase status and plasma butyrylcholinesterase activity in chlorpyrifos manufacturing workers.
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- Journal of Exposure Science & Environmental Epidemiology, 2010, v. 20, n. 1, p. 79, doi. 10.1038/jes.2009.9
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- Article