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Differential expression in humans of the viral entry receptor ACE2 compared with the short deltaACE2 isoform lacking SARS-CoV-2 binding sites.
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- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-03731-9
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- Article
Trans-myocardial Extraction of Endothelin-1 Correlates with Increased Microcirculatory Resistance following Percutaneous Coronary Intervention.
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- 2022
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- Publication type:
- journal article
Human embryonic stem cell-derived cardiomyocyte platform screens inhibitors of SARS-CoV-2 infection.
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- Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02453-y
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- Article
Vasoconstrictor activity of novel endothelin peptide, ET-1(1 - 31), in human mammary and coronary arteries in vitro.
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- 2001
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- journal article
Orphan-receptor ligand human urotensin II: receptor localization in human tissues and comparison of vasoconstrictor responses with endothelin-1.
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- British Journal of Pharmacology, 2000, v. 131, n. 3, p. 441, doi. 10.1038/sj.bjp.0703601
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- Article
Characterization of [<sup>125</sup>I]-PD164333, an ET<sub>A</sub> selective non-peptide radiolabelled antagonist, in normal and diseased human tissues.
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- British Journal of Pharmacology, 1998, v. 123, n. 2, p. 223, doi. 10.1038/sj.bjp.0701597
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- Article
Microarray, qPCR, and KCNJ5 sequencing of aldosterone-producing adenomas reveal differences in genotype and phenotype between zona glomerulosa- and zona fasciculata-like tumors.
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- 2012
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- Publication type:
- journal article
The G Protein Biased Small Molecule Apelin Agonist CMF-019 is Disease Modifying in Endothelial Cell Apoptosis In Vitro and Induces Vasodilatation Without Desensitisation In Vivo.
- Published in:
- Frontiers in Pharmacology, 2021, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.588669
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- Article
Inotropic Action of the Puberty Hormone Kisspeptin in Rat, Mouse and Human: Cardiovascular Distribution and Characteristics of the Kisspeptin Receptor.
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- PLoS ONE, 2011, v. 6, n. 11, p. 1, doi. 10.1371/journal.pone.0027601
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- Article
Apelin is expressed throughout the human kidney, is elevated in chronic kidney disease & associates independently with decline in kidney function.
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- British Journal of Clinical Pharmacology, 2022, v. 88, n. 12, p. 5295, doi. 10.1111/bcp.15446
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- Article
Microarray analysis demonstrates up-regulation of the endothelin-1 gene with compensatory down-regulation of the ET<sub>A</sub> receptor gene in human portal vein.
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- Bioscience Reports, 2024, v. 44, n. 7, p. 1, doi. 10.1042/BSR20240528
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- Article
Co-localization of the sodium-glucose co-transporter-2 channel (SGLT-2) with endothelin ET<sub>A</sub> and ET<sub>B</sub> receptors in human cardiorenal tissue.
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- Bioscience Reports, 2024, v. 44, n. 6, p. 1, doi. 10.1042/BSR20240604
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- Article
The CCR5 chemokine receptor mediates vasoconstriction and stimulates intimal hyperplasia in human vessels in vitro.
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- Cardiovascular Research, 2014, v. 101, n. 3, p. 513, doi. 10.1093/cvr/cvt333
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- Article
Expression and vasoconstrictor function of anorexigenic peptides neuromedin U-25 and S in the human cardiovascular system.
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- Cardiovascular Research, 2009, v. 81, n. 2, p. 353
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- Article
Endothelin-Mediated Vasoconstriction in Early Atherosclerosis Is Markedly Increased in ApoE −/− Mouse but Prevented by Atorvastatin.
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- Experimental Biology & Medicine, 2006, v. 231, n. 6, p. 806, doi. 10.3181/00379727-231-2310806
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- Article
Quantification of Endothelin Receptor Subtypes in Peripheral Tissues Reveals Downregulation of ET<sub>A</sub> Receptors in ET<sub>B</sub>-Deficient Mice.
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- Experimental Biology & Medicine, 2006, v. 231, n. 6, p. 741, doi. 10.3181/00379727-231-2310741
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- Article
Development and validation of an LC-MS/MS method for detection and quantification of in vivo derived metabolites of [Pyr1]apelin-13 in humans.
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- Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-56157-9
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- Article
[Pyr¹]Apelin-13<sub>(1-12)</sub> Is a Biologically Active ACE2 Metabolite of the Endogenous Cardiovascular Peptide [Pyr¹]Apelin-13.
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- Frontiers in Neuroscience, 2017, v. 11, p. 1, doi. 10.3389/fnins.2017.00092
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- Article
Inducible apelin receptor knockdown reduces differentiation efficiency and contractility of hESC-derived cardiomyocytes.
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- Cardiovascular Research, 2023, v. 119, n. 2, p. 587, doi. 10.1093/cvr/cvac065
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- Article
Chemerin Elicits Potent Constrictor Actions via Chemokine-Like Receptor 1 (CMKLR1), not G-Protein-Coupled Receptor 1 (GPR1), in Human and Rat Vasculature.
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- Journal of the American Heart Association, 2016, v. 5, n. 10, p. 1, doi. 10.1161/JAHA.116.004421
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- Article
A novel cyclic biased agonist of the apelin receptor, MM07, is disease modifying in the rat monocrotaline model of pulmonary arterial hypertension.
- Published in:
- 2019
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- Publication type:
- journal article
No evidence for a local renin-angiotensin system in liver mitochondria.
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- Scientific Reports, 2013, p. 1, doi. 10.1038/srep02467
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- Article
The biased apelin receptor agonist, MM07, reverses Sugen/hypoxia-induced pulmonary arterial hypertension as effectively as the endothelin antagonist macitentan.
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- Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1369489
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- Article
Modulation of the apelin/APJ system in heart failure and atherosclerosis in man.
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- 2010
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- Publication type:
- journal article
Regional heterogeneity in the haemodynamic responses to urotensin II infusion in relation to UT receptor localisation.
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- British Journal of Pharmacology, 2006, v. 147, n. 6, p. 612, doi. 10.1038/sj.bjp.0706503
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- Article
Expanding the apelin receptor pharmacological toolbox using novel fluorescent ligands.
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- Frontiers in Endocrinology, 2023, v. 14, p. 1, doi. 10.3389/fendo.2023.1139121
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- Article
Expression of the apelin receptor, a novel potential therapeutic target, and its endogenous ligands in diverse stem cell populations in human glioblastoma.
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- Frontiers in Neuroscience, 2024, p. 1, doi. 10.3389/fnins.2024.1379658
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- Article
Expression of the apelin receptor, a novel potential therapeutic target, and its endogenous ligands in diverse stem cell populations in human glioblastoma.
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- Frontiers in Neuroscience, 2024, p. 01, doi. 10.3389/fnins.2024.1379658
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- Article
Apelin peptides linked to anti‐serum albumin domain antibodies retain affinity in vitro and are efficacious receptor agonists in vivo.
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- Basic & Clinical Pharmacology & Toxicology, 2020, v. 126, p. 96, doi. 10.1111/bcpt.13227
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- Article
Novel ligands BQ123 and BQ3020 characterize endothelin receptor subtypes ET<sub>A</sub> and ET<sub>B</sub> in human kidney.
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- Kidney International, 1993, v. 44, n. 1, p. 36, doi. 10.1038/ki.1993.210
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- Article