Works matching AU Reynisson, Jóhannes
Results: 78
A Multitargeted Approach: Organorhodium Anticancer Agent Based on Vorinostat as a Potent Histone Deacetylase Inhibitor.
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- Angewandte Chemie, 2020, v. 132, n. 34, p. 14717, doi. 10.1002/ange.202005758
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- Article
New Hybrid Compounds Combining Fragments of Usnic Acid and Monoterpenoids for Effective Tyrosyl-DNA Phosphodiesterase 1 Inhibition.
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- Biomolecules (2218-273X), 2021, v. 11, n. 7, p. 973, doi. 10.3390/biom11070973
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- Article
Accessing Active Fragments for Drug Discovery Utilising Nitroreductase Biocatalysis.
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- ChemBioChem, 2024, v. 25, n. 18, p. 1, doi. 10.1002/cbic.202400428
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- Article
New Anti-Seizure (Arylalkyl)azole Derivatives: Synthesis, In Vivo and In Silico Studies.
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- Archiv der Pharmazie, 2017, v. 350, n. 6, p. n/a, doi. 10.1002/ardp.201700043
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- Article
Mutagenic Potential of Nitrenium Ions of Nitrobenzanthrones: Correlation Between Theory and Experiment.
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- Environmental & Molecular Mutagenesis, 2008, v. 49, n. 8, p. 659, doi. 10.1002/em.20411
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- Article
Structural properties of DNO investigated with pyrene excimer formation.
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- Journal of Peptide Science, 2000, v. 6, n. 12, p. 603, doi. 10.1002/1099-1387(200012)6:12<603::AID-PSC281>3.0.CO;2-J
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- Article
The Development of a Weighted Index to Optimise Compound Libraries for High Throughput Screening.
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- Molecular Informatics, 2019, v. 38, n. 3, p. N.PAG, doi. 10.1002/minf.201800068
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- Article
Hydration Free Energy as a Molecular Descriptor in Drug Design: A Feasibility Study.
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- Molecular Informatics, 2016, v. 35, n. 5, p. 207, doi. 10.1002/minf.201501035
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- Article
Defining Known Drug Space Using DFT.
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- Molecular Informatics, 2016, v. 35, n. 2, p. 46, doi. 10.1002/minf.201500105
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- Article
Wine Compounds as a Source for HTS Screening Collections. A Feasibility Study.
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- Molecular Informatics, 2012, v. 31, n. 11/12, p. 847, doi. 10.1002/minf.201200103
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- Article
Size estimation of chemical space: how big is it?
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- Journal of Pharmacy & Pharmacology, 2012, v. 64, n. 4, p. 490, doi. 10.1111/j.2042-7158.2011.01424.x
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- Article
Latonduine-1-Amino-Hydantoin Hybrid, Triazole-Fused Latonduine Schiff Bases and Their Metal Complexes: Synthesis, X-ray and Electron Diffraction, Molecular Docking Studies and Antiproliferative Activity.
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- Inorganics, 2023, v. 11, n. 1, p. 30, doi. 10.3390/inorganics11010030
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- Article
A Chemometric Analysis of Compounds from Native New Zealand Medicinal Flora.
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- Chemistry - An Asian Journal, 2019, v. 14, n. 8, p. 1117, doi. 10.1002/asia.201800803
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- Article
The Utility of Calculated Proton Affinities in Drug Design: A DFT Study.
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- Australian Journal of Chemistry, 2018, v. 71, n. 8, p. 580, doi. 10.1071/CH18225
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- Article
Development and Application of an NMR‐Based Assay for Polyphenol Oxidases.
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- ChemistrySelect, 2017, v. 2, n. 32, p. 10435, doi. 10.1002/slct.201702144
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- Article
Validating TDP1 as an Inhibition Target for the Development of Chemosensitizers for Camptothecin-Based Chemotherapy Drugs.
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- Oncology & Therapy, 2021, v. 9, n. 2, p. 541, doi. 10.1007/s40487-021-00158-0
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- Article
Rapid changes in the ATG5‐ATG16L1 complex following nutrient deprivation measured using NanoLuc Binary Technology (NanoBIT).
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- FEBS Journal, 2020, v. 287, n. 22, p. 4917, doi. 10.1111/febs.15275
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- Article
Sulfide, Sulfoxide, and Sulfone Derivatives of Usnic Acid as Inhibitors of Human TDP1 and TDP2 Enzymes.
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- Chemistry (2624-8549), 2024, v. 6, n. 6, p. 1658, doi. 10.3390/chemistry6060101
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- Article
Organoruthenium and Organoosmium Complexes of 2-Pyridinecarbothioamides Functionalized with a Sulfonamide Motif: Synthesis, Cytotoxicity and Biomolecule Interactions.
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- ChemPlusChem, 2018, v. 83, n. 7, p. 612, doi. 10.1002/cplu.201800194
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- Article
Glycophenotype of breast and prostate cancer stem cells treated with thieno[2,3-b]pyridine anticancer compound.
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- Drug Design, Development & Therapy, 2017, v. 11, p. 759, doi. 10.2147/DDDT.S121122
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- Article
A Multitargeted Approach: Organorhodium Anticancer Agent Based on Vorinostat as a Potent Histone Deacetylase Inhibitor.
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- Angewandte Chemie International Edition, 2020, v. 59, n. 34, p. 14609, doi. 10.1002/anie.202005758
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- Publication type:
- Article
Antifungal screening and in silico mechanistic studies of an in‐house azole library.
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- Chemical Biology & Drug Design, 2019, v. 94, n. 5, p. 1944, doi. 10.1111/cbdd.13587
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- Article
Synthesis and in vitro Biological Evaluation of Ferrocenyl Side-Chain-Functionalized Paclitaxel Derivatives.
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- ChemMedChem, 2017, v. 12, n. 22, p. 1882, doi. 10.1002/cmdc.201700576
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- Article
New 5-Hydroxycoumarin-Based Tyrosyl-DNA Phosphodiesterase I Inhibitors Sensitize Tumor Cell Line to Topotecan.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 11, p. 9155, doi. 10.3390/ijms24119155
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- Article
Novel TDP1 Inhibitors: Disubstituted Thiazolidine-2,4-Diones Containing Monoterpene Moieties.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 4, p. 3834, doi. 10.3390/ijms24043834
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- Article
Novel Thieno [2,3- b ]pyridine Anticancer Compound Lowers Cancer Stem Cell Fraction Inducing Shift of Lipid to Glucose Metabolism.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 19, p. 11457, doi. 10.3390/ijms231911457
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- Article
The First Berberine-Based Inhibitors of Tyrosyl-DNA Phosphodiesterase 1 (Tdp1), an Important DNA Repair Enzyme.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 19, p. 7162, doi. 10.3390/ijms21197162
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- Article
Promising New Inhibitors of Tyrosyl-DNA Phosphodiesterase I (Tdp 1) Combining 4-Arylcoumarin and Monoterpenoid Moieties as Components of Complex Antitumor Therapy.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 1, p. 126, doi. 10.3390/ijms21010126
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- Article
Identification of Isoform-Selective Ligands for the Middle Domain of Heat Shock Protein 90 (Hsp90).
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- International Journal of Molecular Sciences, 2019, v. 20, n. 21, p. 5333, doi. 10.3390/ijms20215333
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- Article
New Dual Inhibitors of Tyrosyl-DNA Phosphodiesterase 1 and 2 Based on Deoxycholic Acid: Design, Synthesis, Cytotoxicity, and Molecular Modeling.
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- Molecules, 2024, v. 29, n. 3, p. 581, doi. 10.3390/molecules29030581
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- Article
Phosphatidylcholine-Specific Phospholipase C as a Promising Drug Target.
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- Molecules, 2023, v. 28, n. 15, p. 5637, doi. 10.3390/molecules28155637
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- Article
New Myrtenal–Adamantane Conjugates Alleviate Alzheimer's-Type Dementia in Rat Model.
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- Molecules, 2022, v. 27, n. 17, p. 5456, doi. 10.3390/molecules27175456
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- Article
Adamantane-Monoterpenoid Conjugates Linked via Heterocyclic Linkers Enhance the Cytotoxic Effect of Topotecan.
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- Molecules, 2022, v. 27, n. 11, p. 3374, doi. 10.3390/molecules27113374
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- Article
Conjugation of Palbociclib with MHI-148 Has an Increased Cytotoxic Effect for Breast Cancer Cells and an Altered Mechanism of Action.
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- Molecules, 2022, v. 27, n. 3, p. 880, doi. 10.3390/molecules27030880
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- Article
Discovery and Characterization of a Cryptic Secondary Binding Site in the Molecular Chaperone HSP70.
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- Molecules, 2022, v. 27, n. 3, p. 817, doi. 10.3390/molecules27030817
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- Article
New Deoxycholic Acid Derived Tyrosyl-DNA Phosphodiesterase 1 Inhibitors Also Inhibit Tyrosyl-DNA Phosphodiesterase 2.
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- Molecules, 2022, v. 27, n. 1, p. 72, doi. 10.3390/molecules27010072
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- Article
Novel Tdp1 Inhibitors Based on Adamantane Connected with Monoterpene Moieties via Heterocyclic Fragments.
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- Molecules, 2021, v. 26, n. 11, p. 3128, doi. 10.3390/molecules26113128
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- Article
Discovery of Novel Sultone Fused Berberine Derivatives as Promising Tdp1 Inhibitors.
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- Molecules, 2021, v. 26, n. 7, p. 1945, doi. 10.3390/molecules26071945
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- Article
Advances in Anticancer Drug Discovery.
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- 2021
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- Publication type:
- Editorial
Recent Advances in Tannic Acid (Gallotannin) Anticancer Activities and Drug Delivery Systems for Efficacy Improvement; A Comprehensive Review.
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- Molecules, 2021, v. 26, n. 5, p. 1486, doi. 10.3390/molecules26051486
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- Article
A Pyranoxanthone as a Potent Antimitotic and Sensitizer of Cancer Cells to Low Doses of Paclitaxel.
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- Molecules, 2020, v. 25, n. 24, p. 5845, doi. 10.3390/molecules25245845
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- Article
Hybrides of Alkaloid Lappaconitine with Pyrimidine Motif on the Anthranilic Acid Moiety: Design, Synthesis, and Investigation of Antinociceptive Potency.
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- Molecules, 2020, v. 25, n. 23, p. 5578, doi. 10.3390/molecules25235578
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- Article
Role of Bcl-2 Family Proteins in Photodynamic Therapy Mediated Cell Survival and Regulation.
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- Molecules, 2020, v. 25, n. 22, p. 5308, doi. 10.3390/molecules25225308
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- Article
Synthesis, Anti-proliferative Activity, and Molecular Docking Study of New Series of 1,3-5-Triazine Schiff Base Derivatives.
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- Molecules, 2020, v. 25, n. 18, p. 4065, doi. 10.3390/molecules25184065
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- Article
Thiourea-Derived Chelating Ligands and Their Organometallic Compounds: Investigations into Their Anticancer Activity.
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- Molecules, 2020, v. 25, n. 16, p. 3661, doi. 10.3390/molecules25163661
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- Article
Design, Synthesis, and Biological Investigation of Novel Classes of 3-Carene-Derived Potent Inhibitors of TDP1.
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- Molecules, 2020, v. 25, n. 15, p. 3496, doi. 10.3390/molecules25153496
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- Article
Involvement of Integrin-Activating Peptides Derived from Tenascin-C in Cancer Aggression and New Anticancer Strategy Using the Fibronectin-Derived Integrin-Inactivating Peptide.
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- Molecules, 2020, v. 25, n. 14, p. 3239, doi. 10.3390/molecules25143239
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- Article
10-Gingerol Targets Lipid Rafts Associated PI3K/Akt Signaling in Radio-Resistant Triple Negative Breast Cancer Cells.
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- Molecules, 2020, v. 25, n. 14, p. 3164, doi. 10.3390/molecules25143164
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- Article
Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes–7.
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- 2020
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- Publication type:
- Editorial
How 'Protein-Docking' Translates into the New Emerging Field of Docking Small Molecules to Nucleic Acids?
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- Molecules, 2020, v. 25, n. 12, p. 2749, doi. 10.3390/molecules25122749
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- Article