Works matching AU Reynisson, Jóhannes

Results: 79
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    Defining Known Drug Space Using DFT.

    Published in:
    Molecular Informatics, 2016, v. 35, n. 2, p. 46, doi. 10.1002/minf.201500105
    By:
    • Matuszek, Anna M.;
    • Reynisson, Jóhannes
    Publication type:
    Article
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    New 5-Hydroxycoumarin-Based Tyrosyl-DNA Phosphodiesterase I Inhibitors Sensitize Tumor Cell Line to Topotecan.

    Published in:
    International Journal of Molecular Sciences, 2023, v. 24, n. 11, p. 9155, doi. 10.3390/ijms24119155
    By:
    • Khomenko, Tatyana M.;
    • Zakharenko, Alexandra L.;
    • Kornienko, Tatyana E.;
    • Chepanova, Arina A.;
    • Dyrkheeva, Nadezhda S.;
    • Artemova, Anastasia O.;
    • Korchagina, Dina V.;
    • Achara, Chigozie;
    • Curtis, Anthony;
    • Reynisson, Jóhannes;
    • Volcho, Konstantin P.;
    • Salakhutdinov, Nariman F.;
    • Lavrik, Olga I.
    Publication type:
    Article
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    Novel TDP1 Inhibitors: Disubstituted Thiazolidine-2,4-Diones Containing Monoterpene Moieties.

    Published in:
    International Journal of Molecular Sciences, 2023, v. 24, n. 4, p. 3834, doi. 10.3390/ijms24043834
    By:
    • Ivankin, Dmitry I.;
    • Kornienko, Tatyana E.;
    • Mikhailova, Marina A.;
    • Dyrkheeva, Nadezhda S.;
    • Zakharenko, Alexandra L.;
    • Achara, Chigozie;
    • Reynisson, Jóhannes;
    • Golyshev, Victor M.;
    • Luzina, Olga A.;
    • Volcho, Konstantin P.;
    • Salakhutdinov, Nariman F.;
    • Lavrik, Olga I.
    Publication type:
    Article
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    The First Berberine-Based Inhibitors of Tyrosyl-DNA Phosphodiesterase 1 (Tdp1), an Important DNA Repair Enzyme.

    Published in:
    International Journal of Molecular Sciences, 2020, v. 21, n. 19, p. 7162, doi. 10.3390/ijms21197162
    By:
    • Gladkova, Elizaveta D.;
    • Nechepurenko, Ivan V.;
    • Bredikhin, Roman A.;
    • Chepanova, Arina A.;
    • Zakharenko, Alexandra L.;
    • Luzina, Olga A.;
    • Ilina, Ekaterina S.;
    • Dyrkheeva, Nadezhda S.;
    • Mamontova, Evgeniya M.;
    • Anarbaev, Rashid O.;
    • Reynisson, Jóhannes;
    • Volcho, Konstantin P.;
    • Salakhutdinov, Nariman F.;
    • Lavrik, Olga I.
    Publication type:
    Article
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    Promising New Inhibitors of Tyrosyl-DNA Phosphodiesterase I (Tdp 1) Combining 4-Arylcoumarin and Monoterpenoid Moieties as Components of Complex Antitumor Therapy.

    Published in:
    International Journal of Molecular Sciences, 2020, v. 21, n. 1, p. 126, doi. 10.3390/ijms21010126
    By:
    • Khomenko, Tatyana M.;
    • Zakharenko, Alexandra L.;
    • Chepanova, Arina A.;
    • Ilina, Ekaterina S.;
    • Zakharova, Olga D.;
    • Kaledin, Vasily I.;
    • Nikolin, Valeriy P.;
    • Popova, Nelly A.;
    • Korchagina, Dina V.;
    • Reynisson, Jóhannes;
    • Chand, Raina;
    • Ayine-Tora, Daniel M.;
    • Patel, Jinal;
    • Leung, Ivanhoe K. H.;
    • Volcho, Konstantin P.;
    • Salakhutdinov, Nariman F.;
    • Lavrik, Olga I.
    Publication type:
    Article
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    The Development of Tyrosyl-DNA Phosphodiesterase 1 Inhibitors. Combination of Monoterpene and Adamantine Moieties via Amide or Thioamide Bridges.

    Published in:
    Applied Sciences (2076-3417), 2019, v. 9, n. 13, p. 2767, doi. 10.3390/app9132767
    By:
    • Chepanova, Arina A.;
    • Mozhaitsev, Evgenii S.;
    • Munkuev, Aldar A.;
    • Suslov, Evgeniy V.;
    • Korchagina, Dina V.;
    • Zakharova, Olga D.;
    • Zakharenko, Alexandra L.;
    • Patel, Jinal;
    • Ayine-Tora, Daniel M.;
    • Reynisson, Jóhannes;
    • Leung, Ivanhoe K. H.;
    • Volcho, Konstantin P.;
    • Salakhutdinov, Nariman F.;
    • Lavrik, Olga I.
    Publication type:
    Article
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    A Multitargeted Approach: Organorhodium Anticancer Agent Based on Vorinostat as a Potent Histone Deacetylase Inhibitor.

    Published in:
    Angewandte Chemie International Edition, 2020, v. 59, n. 34, p. 14609, doi. 10.1002/anie.202005758
    By:
    • Hanif, Muhammad;
    • Arshad, Jahanzaib;
    • Astin, Jonathan W.;
    • Rana, Zohaib;
    • Zafar, Ayesha;
    • Movassaghi, Sanam;
    • Leung, Euphemia;
    • Patel, Kamal;
    • Söhnel, Tilo;
    • Reynisson, Jóhannes;
    • Sarojini, Vijayalekshmi;
    • Rosengren, Rhonda J.;
    • Jamieson, Stephen M. F.;
    • Hartinger, Christian G.
    Publication type:
    Article
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    New Hybrid Compounds Combining Fragments of Usnic Acid and Monoterpenoids for Effective Tyrosyl-DNA Phosphodiesterase 1 Inhibition.

    Published in:
    Biomolecules (2218-273X), 2021, v. 11, n. 7, p. 973, doi. 10.3390/biom11070973
    By:
    • Dyrkheeva, Nadezhda S.;
    • Filimonov, Aleksandr S.;
    • Luzina, Olga A.;
    • Zakharenko, Alexandra L.;
    • Ilina, Ekaterina S.;
    • Malakhova, Anastasia A.;
    • Medvedev, Sergey P.;
    • Reynisson, Jóhannes;
    • Volcho, Konstantin P.;
    • Zakian, Suren M.;
    • Salakhutdinov, Nariman F.;
    • Lavrik, Olga I.
    Publication type:
    Article
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    Half-Sandwich Ruthenium(II) Biotin Conjugates as Biological Vectors to Cancer Cells.

    Published in:
    Chemistry - A European Journal, 2015, v. 21, n. 13, p. 5110, doi. 10.1002/chem.201403974
    By:
    • Babak, Maria V.;
    • Plażuk, Damian;
    • Meier, Samuel M.;
    • Arabshahi, Homayon John;
    • Reynisson, Jóhannes;
    • Rychlik, Błażej;
    • Błauż, Andrzej;
    • Szulc, Katarzyna;
    • Hanif, Muhammad;
    • Strobl, Sebastian;
    • Roller, Alexander;
    • Keppler, Bernhard K.;
    • Hartinger, Christian G.
    Publication type:
    Article
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    Sulfide, Sulfoxide, and Sulfone Derivatives of Usnic Acid as Inhibitors of Human TDP1 and TDP2 Enzymes.

    Published in:
    Chemistry (2624-8549), 2024, v. 6, n. 6, p. 1658, doi. 10.3390/chemistry6060101
    By:
    • Filimonov, Aleksandr S.;
    • Mikhailova, Marina A.;
    • Dyrkheeva, Nadezhda S.;
    • Chernyshova, Irina A.;
    • Kornienko, Tatyana E.;
    • Naumenko, Konstantin A.;
    • Anarbaev, Rashid O.;
    • Nefedov, Andrey A.;
    • Achara, Chigozie;
    • Curtis, Anthony D. M.;
    • Luzina, Olga A.;
    • Volcho, Konstantin P.;
    • Salakhutdinov, Nariman F.;
    • Lavrik, Olga I.;
    • Reynisson, Jóhannes
    Publication type:
    Article
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    Size estimation of chemical space: how big is it?

    Published in:
    Journal of Pharmacy & Pharmacology, 2012, v. 64, n. 4, p. 490, doi. 10.1111/j.2042-7158.2011.01424.x
    By:
    • Drew, Kurt L. M.;
    • Baiman, Hakim;
    • Khwaounjoo, Prashanna;
    • Yu, Bo;
    • Reynisson, Jóhannes
    Publication type:
    Article
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    Validating TDP1 as an Inhibition Target for the Development of Chemosensitizers for Camptothecin-Based Chemotherapy Drugs.

    Published in:
    Oncology & Therapy, 2021, v. 9, n. 2, p. 541, doi. 10.1007/s40487-021-00158-0
    By:
    • Leung, Euphemia;
    • Patel, Jinal;
    • Hollywood, Jennifer A.;
    • Zafar, Ayesha;
    • Tomek, Petr;
    • Barker, David;
    • Pilkington, Lisa I.;
    • van Rensburg, Michelle;
    • Langley, Ries J.;
    • Helsby, Nuala A.;
    • Squire, Christopher J.;
    • Baguley, Bruce C.;
    • Denny, William A.;
    • Reynisson, Jóhannes;
    • Leung, Ivanhoe K. H.
    Publication type:
    Article
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    New Myrtenal–Adamantane Conjugates Alleviate Alzheimer's-Type Dementia in Rat Model.

    Published in:
    Molecules, 2022, v. 27, n. 17, p. 5456, doi. 10.3390/molecules27175456
    By:
    • Dragomanova, Stela;
    • Lazarova, Maria;
    • Munkuev, Aldar;
    • Suslov, Evgeniy;
    • Volcho, Konstantin;
    • Salakhutdinov, Nariman;
    • Bibi, Amina;
    • Reynisson, Jóhannes;
    • Tzvetanova, Elina;
    • Alexandrova, Albena;
    • Georgieva, Almira;
    • Uzunova, Diamara;
    • Stefanova, Miroslava;
    • Kalfin, Reni;
    • Tancheva, Lyubka
    Publication type:
    Article
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    Adamantane-Monoterpenoid Conjugates Linked via Heterocyclic Linkers Enhance the Cytotoxic Effect of Topotecan.

    Published in:
    Molecules, 2022, v. 27, n. 11, p. 3374, doi. 10.3390/molecules27113374
    By:
    • Munkuev, Aldar A.;
    • Dyrkheeva, Nadezhda S.;
    • Kornienko, Tatyana E.;
    • Ilina, Ekaterina S.;
    • Ivankin, Dmitry I.;
    • Suslov, Evgeniy V.;
    • Korchagina, Dina V.;
    • Gatilov, Yuriy V.;
    • Zakharenko, Alexandra L.;
    • Malakhova, Anastasia A.;
    • Reynisson, Jóhannes;
    • Volcho, Konstantin P.;
    • Salakhutdinov, Nariman F.;
    • Lavrik, Olga I.
    Publication type:
    Article
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