Works matching AU Rettie, Allan E.

Results: 48

Functional analysis of CYP4B1 enzymes from apes and humans uncovers evolutionary hot spots for adaptations of the catalytical function.

Published in:

PLoS Genetics, 2025, v. 21, n. 6, p. 1, doi. 10.1371/journal.pgen.1011750

By:

Hüsken, Saskia;
Röder, Annika;
Ptok, Johannes;
Meyer, Anne E.;
Georg, Mats;
Schwarz, Yannick;
Roos, Christian;
Mätz-Rensing, Kerstin;
Hutter, Michael C.;
Floss, Doreen M.;
Rettie, Allan E.;
Girhard, Marco;
Hanenberg, Helmut;
Wiek, Constanze

Publication type:

Article

Ocular cytochrome P450s and transporters: roles in disease and endobiotic and xenobiotic disposition.

Published in:

Drug Metabolism Reviews, 2014, v. 46, n. 3, p. 247, doi. 10.3109/03602532.2014.921190

By:

Nakano, Mariko;
Lockhart, Catherine M.;
Kelly, Edward J.;
Rettie, Allan E.

Publication type:

Article

Pharmacogenomics of 4-Hydroxycoumarin Anticoagulants.

Published in:

Drug Metabolism Reviews, 2008, v. 40, n. 2, p. 355, doi. 10.1080/03602530801952187

By:

Au, Nicholas;
Rettie, Allan E.

Publication type:

Article

Preface.

Published in:

Drug Metabolism Reviews, 2008, v. 40, n. 2, p. 185, doi. 10.1080/03602530801952898

By:

Rettie, Allan E.

Publication type:

Article

CYP4B1: An Enigmatic P450 at the Interface between Xenobiotic and Endobiotic Metabolism.

Published in:

Drug Metabolism Reviews, 2006, v. 38, n. 3, p. 451, doi. 10.1080/03602530600688503

By:

Baer, Brian R.;
Rettie, Allan E.

Publication type:

Article

Pharmacokinetics, metabolism and off-target effects in the rat of 8-[(1H- benzotriazol-1-yl)amino]octanoic acid, a selective inhibitor of human cytochrome P450 4Z1: β-oxidation as a potential augmenting pathway for inhibition.

Published in:

Xenobiotica, 2021, v. 51, n. 8, p. 901, doi. 10.1080/00498254.2021.1930281

By:

Kowalski, John P.;
Pelletier, Robert D.;
McDonald, Matthew G.;
Kelly, Edward J.;
Rettie, Allan E.

Publication type:

Article

Human Valacyclovir Hydrolase/Biphenyl Hydrolase-Like Protein Is a Highly Efficient Homocysteine Thiolactonase.

Published in:

PLoS ONE, 2014, v. 9, n. 10, p. 1, doi. 10.1371/journal.pone.0110054

By:

Marsillach, Judit;
Suzuki, Stephanie M.;
Richter, Rebecca J.;
McDonald, Matthew G.;
Rademacher, Peter M.;
MacCoss, Michael J.;
Hsieh, Edward J.;
Rettie, Allan E.;
Furlong, Clement E.

Publication type:

Article

Structure-Activity Relationships of Benzbromarone Metabolites and Derivatives as EYA Inhibitory Anti-Angiogenic Agents.

Published in:

PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0084582

By:

Pandey, Ram Naresh;
Wang, Tim Sen;
Tadjuidje, Emmanuel;
McDonald, Matthew G.;
Rettie, Allan E.;
Hegde, Rashmi S.

Publication type:

Article

Mutation of the conserved I-helix threonine in CYP2C9 eliminates heteroactivation.

Published in:

FASEB Journal, 2007, v. 21, n. 6, p. A1185

By:

Tracy, Timothy Scott;
Lian Wei;
Locuson, Charles W.;
Mosher, Carrie;
Rettie, Allan E.

Publication type:

Article

Novel Hispanic American CYP2C9 Genetic Variants and Assessment of Their Impact on Gene Expression.

Published in:

FASEB Journal, 2007, v. 21, n. 5, p. A415

By:

Kramer, Melissa A.;
Rettie, Allan E.;
Rieder, Mark J.;
Hines, Ronald N.

Publication type:

Article

In Vitro Methods for Assessing Human Hepatic Drug Metabolism: Their use in Drug Development.

Published in:

Drug Metabolism Reviews, 1993, v. 25, n. 4, p. 453, doi. 10.3109/03602539308993982

By:

Wrighton, Steven A.;
Vandenbranden, Mark;
Stevens, Jeffrey C.;
Shipley, Lisa A.;
Ring, Barbara J.;
Cashman, John R.;
Rettie, Allan E.

Publication type:

Article

Deep mutational scanning of CYP2C19 in human cells reveals a substrate specificity-abundance tradeoff.

Published in:

Genetics, 2024, v. 228, n. 3, p. 1, doi. 10.1093/genetics/iyae156

By:

Boyle, Gabriel E;
Sitko, Katherine A;
Galloway, Jared G;
Haddox, Hugh K;
Bianchi, Aisha Haley;
Dixon, Ajeya;
Wheelock, Melinda K;
Vandi, Allyssa J;
Wang, Ziyu R;
Thomson, Raine E S;
Garge, Riddhiman K;
Rettie, Allan E;
Rubin, Alan F;
Geck, Renee C;
Gillam, Elizabeth M J;
DeWitt, William S;
Matsen, Frederick A;
Fowler, Douglas M

Publication type:

Article

Dietary and genetic influences on hemostasis in a Yup’ik Alaska Native population.

Published in:

PLoS ONE, 2017, v. 12, n. 4, p. 1, doi. 10.1371/journal.pone.0173616

By:

Au, Nicholas T.;
Reyes, Morayma;
Boyer, Bert B.;
Hopkins, Scarlett E.;
Black, Jynene;
O’Brien, Diane;
Fohner, Alison E.;
Yracheta, Joe;
Thornton, Timothy;
Austin, Melissa A.;
Burke, Wylie;
Thummel, Kenneth E.;
Rettie, Allan E.

Publication type:

Article

CYP2C9 Genotype-Dependent Warfarin Pharmacokinetics: Impact of CYP2C9 Genotype on R- and S-Warfarin and Their Oxidative Metabolites.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, n. 3, p. 382, doi. 10.1002/jcph.813

By:

Flora, Darcy R.;
Rettie, Allan E.;
Brundage, Richard C.;
Tracy, Timothy S.

Publication type:

Article

Effects of Oral Vitamin K on S-and R-Warfarin Pharmacokinetics and Pharmacodynamics: Enhanced Safety of Warfarin as a CYP2C9 Probe.

Published in:

Journal of Clinical Pharmacology, 2001, v. 41, n. 7, p. 715, doi. 10.1177/009127000104100703

By:

Kim, Jooran S.;
Nafziger, Anne N.;
Gaedigk, Andrea;
Dickmann, Leslie J.;
Rettie, Allan E.;
Bertino, Joseph S.

Publication type:

Article

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2C9 and HLA‐B Genotypes and Phenytoin Dosing: 2020 Update.

Published in:

Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 2, p. 302, doi. 10.1002/cpt.2008

By:

Karnes, Jason H.;
Rettie, Allan E.;
Somogyi, Andrew A.;
Huddart, Rachel;
Fohner, Alison E.;
Formea, Christine M.;
Ta Michael Lee, Ming;
Llerena, Adrian;
Whirl‐Carrillo, Michelle;
Klein, Teri E.;
Phillips, Elizabeth J.;
Mintzer, Scott;
Gaedigk, Andrea;
Caudle, Kelly E.;
Callaghan, John T.

Publication type:

Article

Applying Multiplex Assays to Understand Variation in Pharmacogenes.

Published in:

Clinical Pharmacology & Therapeutics, 2019, v. 106, n. 2, p. 290, doi. 10.1002/cpt.1468

By:

Chiasson, Melissa;
Dunham, Maitreya J.;
Rettie, Allan E.;
Fowler, Douglas M.

Publication type:

Article

CYP2C9 haplotype structure in European American warfarin patients and association with clinical outcomes.

Published in:

Clinical Pharmacology & Therapeutics, 2005, v. 77, n. 5, p. 353, doi. 10.1016/j.clpt.2005.01.019

By:

Veenstra, David L.;
Blough, David K.;
Higashi, Mitchell K.;
Farin, Frederico M.;
Srinouanprachan, Sengkeo;
Rieder, Mark J.;
Rettie, Allan E.

Publication type:

Article

Cytochrome P450 2C8: Substrates, inhibitors, harmacogenetics, and clinical relevance.

Published in:

Clinical Pharmacology & Therapeutics, 2005, v. 77, n. 5, p. 341, doi. 10.1016/j.clpt.2004.12.267

By:

Totah, Rheem A.;
Rettie, Allan E.

Publication type:

Article

Cytochrome P4502C9 activity in end-stage renal disease<sup>*</sup>.

Published in:

Clinical Pharmacology & Therapeutics, 2003, v. 73, n. 5, p. 475, doi. 10.1016/S0009-9236(03)00015-8

By:

Dreisbach, Albert W.;
Japa, Shanker;
Gebrekal, Aster B.;
Mowry, Sarah E.;
Lertora, Juan J. L.;
Kamath, Burde L.;
Rettie, Allan E.

Publication type:

Article

Localization of CYP4B1 in the rat nasal cavity and analysis of CYPs as secreted proteins.

Published in:

Journal of Biochemical & Molecular Toxicology, 2006, v. 20, n. 3, p. 139, doi. 10.1002/jbt.20123

By:

Genter, Mary Beth;
Yost, Garold S.;
Rettie, Allan E.

Publication type:

Article

Experimental pharmacology in precision medicine.

Published in:

Pharmacology Research & Perspectives, 2023, v. 11, n. 6, p. 1, doi. 10.1002/prp2.1147

By:

Urbaniak, Alicja;
Thummel, Kenneth E.;
Alade, Ayoade N.;
Rettie, Allan E.;
Prasad, Bhagwat;
De Nicolò, Amedeo;
Martin, Jennifer H.;
Sheppard, David N.;
Jarvis, Michael F.

Publication type:

Article

A case study of acenocoumarol sensitivity and genotype-phenotype discordancy explained by combinations of polymorphisms in VKORC1 and CYP2C9.

Published in:

British Journal of Clinical Pharmacology, 2006, v. 62, n. 5, p. 617, doi. 10.1111/j.1365-2125.2006.02688.x

By:

Rettie, Allan E.;
Farin, Frederico M.;
Beri, Nitasha G.;
Srinouanprachanh, Sengkeo L.;
Rieder, Mark J.;
Thijssen, Henk H.

Publication type:

Article

In vitro evaluation of potentialin vivo probes for human flavin-containing monooxygenase (FMO): metabolism of benzydamine and caffeine by FMO and P450 isoforms.

Published in:

British Journal of Clinical Pharmacology, 2000, v. 50, n. 4, p. 311, doi. 10.1046/j.1365-2125.2000.00265.x

By:

Lang, Dieter H.;
Rettie, Allan E.

Publication type:

Article

Association Between CYP2C9 Genetic Variants and Anticoagulation-Related Outcomes During Warfarin Therapy.

Published in:

JAMA: Journal of the American Medical Association, 2002, v. 287, n. 13, p. 1690, doi. 10.1001/jama.287.13.1690

By:

Higashi, Mitchell K.;
Veenstra, David L.;
Kondo, L. Midori;
Wittkowsky, Ann K.;
Srinouanprachanh, Sengkeo L.;
Farin, Fred M.;
Rettie, Allan E.

Publication type:

Article

Preface to Special Issue on 'Cytochrome P450 Variation in Pharmacogenomics'.

Published in:

2018

By:

Rettie, Allan E.;
Liggett, Stephen B.

Publication type:

Editorial

Pharmacogenomics of CYP2C9: Functional and Clinical Considerations.

Published in:

Journal of Personalized Medicine, 2018, v. 8, n. 1, p. 1, doi. 10.3390/jpm8010001

By:

Daly, Ann K.;
Rettie, Allan E.;
Fowler, Douglas M.;
Miners, John O.

Publication type:

Article

Association of FMO3 Variants and Trimethylamine N-Oxide Concentration, Disease Progression, and Mortality in CKD Patients.

Published in:

PLoS ONE, 2016, v. 11, n. 8, p. 1, doi. 10.1371/journal.pone.0161074

By:

Robinson-Cohen, Cassianne;
Newitt, Richard;
Shen, Danny D.;
Rettie, Allan E.;
Kestenbaum, Bryan R.;
Himmelfarb, Jonathan;
Yeung, Catherine K.

Publication type:

Article

Characterization of an Additional Splice Acceptor Site Introduced into CYP4B1 in Hominoidae during Evolution.

Published in:

PLoS ONE, 2015, v. 10, n. 9, p. 1, doi. 10.1371/journal.pone.0137110

By:

Schmidt, Eva M.;
Wiek, Constanze;
Parkinson, Oliver T.;
Roellecke, Katharina;
Freund, Marcel;
Gombert, Michael;
Lottmann, Nadine;
Steward, Charles A.;
Kramm, Christof M.;
Yarov-Yarovoy, Vladimir;
Rettie, Allan E.;
Hanenberg, Helmut

Publication type:

Article

Ligand characterization of CYP4B1 isoforms modified for high-level expression in Escherichia coli and HepG2 cells.

Published in:

PEDS: Protein Engineering, Design & Selection, 2017, v. 30, n. 3, p. 205, doi. 10.1093/protein/gzw075

By:

Roellecke, Katharina;
Gyurov, Veselin H.;
Kowalski, John P.;
Mielke, Stephanie;
Rettie, Allan E.;
Hanenberg, Helmut;
Wiek, Constanze;
Girhard, Marco

Publication type:

Article

Inhibition of human liver microsomal epoxide hydrolase by valproate and valpromide: In vitro/in vivo correlation.

Published in:

Clinical Pharmacology & Therapeutics, 1989, v. 46, n. 1, p. 82, doi. 10.1038/clpt.1989.110

By:

Kerr, Bradley M;
Rettie, Allan E;
Eddy, A Craig;
Loiseau, Pierre;
Guyot, Martine;
Wilensky, Alan J;
Levy, René H

Publication type:

Article

Interaction of amiodarone with racemic warfarin and its separated enantiomorphs in humans.

Published in:

Clinical Pharmacology & Therapeutics, 1987, v. 42, n. 3, p. 290, doi. 10.1038/clpt.1987.149

By:

O'Reilly, Robert A;
Trager, William F;
Rettie, Allan E;
Goulart, Darklis A

Publication type:

Article

Valproate hydroxylation by human fetal tissues and embryotoxicity of metabolites.

Published in:

Clinical Pharmacology & Therapeutics, 1986, v. 40, n. 2, p. 172, doi. 10.1038/clpt.1986.160

By:

Rettie, Allan E;
Rettenmeier, Albert W;
Beyer, Bruce K;
Baillie, Thomas A;
Juchau, Mont R

Publication type:

Article

Adapting regulatory drug‐drug interaction guidance to design clinical pharmacokinetic natural product‐drug interaction studies: A NaPDI Center recommended approach.

Published in:

CTS: Clinical & Translational Science, 2022, v. 15, n. 2, p. 322, doi. 10.1111/cts.13172

By:

Cox, Emily J.;
Rettie, Allan E.;
Unadkat, Jashvant D.;
Thummel, Kenneth E.;
McCune, Jeannine S.;
Paine, Mary F.

Publication type:

Article

Associations of CYP2C9 and CYP2C19 Pharmacogenetic Variation with Phenytoin‐Induced Cutaneous Adverse Drug Reactions.

Published in:

CTS: Clinical & Translational Science, 2020, v. 13, n. 5, p. 1004, doi. 10.1111/cts.12787

By:

Fohner, Alison E.;
Rettie, Allan E.;
Thai, Khanh K.;
Ranatunga, Dilrini K.;
Lawson, Brian L.;
Liu, Vincent X.;
Schaefer, Catherine A.

Publication type:

Article

A Novel LC‐MS/MS Assay for Quantification of Des‐carboxy Prothrombin and Characterization of Warfarin‐Induced Changes.

Published in:

CTS: Clinical & Translational Science, 2020, v. 13, n. 4, p. 718, doi. 10.1111/cts.12757

By:

Basit, Abdul;
Prasad, Bhagwat;
Estergreen, Joanne K.;
Sabath, Daniel E.;
Alade, Nathan;
Veenstra, David L.;
Rettie, Allan E.;
Thummel, Kenneth E.

Publication type:

Article

Interrogation of CYP2D6 Structural Variant Alleles Improves the Correlation Between CYP2D6 Genotype and CYP2D6‐Mediated Metabolic Activity.

Published in:

CTS: Clinical & Translational Science, 2020, v. 13, n. 1, p. 147, doi. 10.1111/cts.12695

By:

Dalton, Rachel;
Lee, Seung‐been;
Claw, Katrina G.;
Prasad, Bhagwat;
Phillips, Brian R.;
Shen, Danny D.;
Wong, Lai Hong;
Fade, Mitch;
McDonald, Matthew G.;
Dunham, Maitreya J.;
Fowler, Douglas M.;
Rettie, Allan E.;
Schuetz, Erin;
Thornton, Timothy A.;
Nickerson, Deborah A.;
Gaedigk, Andrea;
Thummel, Kenneth E.;
Woodahl, Erica L.

Publication type:

Article

VKORC1 and Novel CYP2C9 Variation Predict Warfarin Response in Alaska Native and American Indian People.

Published in:

CTS: Clinical & Translational Science, 2019, v. 12, n. 3, p. 312, doi. 10.1111/cts.12611

By:

Henderson, Lindsay M.;
Robinson, Renee F.;
Ray, Lily;
Khan, Burhan A.;
Li, Tianran;
Dillard, Denise A.;
Schilling, Brian D.;
Mosley, Mike;
Janssen, Patricia L.;
Fohner, Alison E.;
Rettie, Allan E.;
Thummel, Kenneth E.;
Thornton, Timothy A.;
Veenstra, David L.

Publication type:

Article

Dietary Vitamin K and Association with Hepatic Vitamin K Status in a Yup'ik Study Population from Southwestern Alaska.

Published in:

Molecular Nutrition & Food Research, 2018, v. 62, n. 3, p. 1, doi. 10.1002/mnfr.201700746

By:

Au, Nicholas T.;
Ryman, Tove;
Rettie, Allan E.;
Hopkins, Scarlett E.;
Boyer, Bert B.;
Black, Jynene;
Philip, Jacques;
Yracheta, Joseph;
Fohner, Alison E.;
Reyes, Morayma;
Thornton, Timothy A.;
Austin, Melissa A.;
Thummel, Kenneth E.

Publication type:

Article

ω-Hydroxylation of phylloquinone by CYP4F2 is not increased by α-tocopherol.

Published in:

Molecular Nutrition & Food Research, 2013, v. 57, n. 10, p. 1785, doi. 10.1002/mnfr.201200797

By:

Farley, Sherry M.;
Leonard, Scott W.;
Taylor, Alan W.;
Birringer, Marc;
Edson, Katheryne Z.;
Rettie, Allan E.;
Traber, Maret G.

Publication type:

Article

Spotlight on CYP4B1.

Published in:

2023

By:

Röder, Annika;
Hüsken, Saskia;
Hutter, Michael C.;
Rettie, Allan E.;
Hanenberg, Helmut;
Wiek, Constanze;
Girhard, Marco

Publication type:

Literature Review

Identification of amino acid determinants in CYP4B1 for optimal catalytic processing of 4-ipomeanol.

Published in:

Biochemical Journal, 2015, v. 465, n. 1, p. 103, doi. 10.1042/BJ20140813

By:

Wiek, Constanze;
Schmidt, Eva M.;
Roellecke, Katharina;
Freund, Marcel;
Nakano, Mariko;
Kelly, Edward J.;
Kaisers, Wolfgang;
Yarov-Yarovoy, Vladimir;
Kramm, Christof M.;
Rettie, Allan E.;
Hanenberg, Helmut

Publication type:

Article

The Prevalence of CYP2C8, 2C9, 2J2, and Soluble Epoxide Hydrolase Polymorphisms in African Americans With Hypertension

Published in:

American Journal of Hypertension, 2005, v. 18, n. 10, p. 1276, doi. 10.1016/j.amjhyper.2005.04.019

By:

Dreisbach, Albert W.;
Japa, Shanker;
Sigel, Aster;
Parenti, Melissa B.;
Hess, Arthur E.;
Srinouanprachanh, Sengkeo L.;
Rettie, Allan E.;
Kim, Helen;
Farin, Federico M.;
Hamm, L. Lee;
Lertora, Juan J.L.

Publication type:

Article

Clinical Pharmacokinetic Assessment of Kratom (Mitragyna speciosa), a Botanical Product with Opioid-like Effects, in Healthy Adult Participants.

Published in:

Pharmaceutics, 2022, v. 14, n. 3, p. 620, doi. 10.3390/pharmaceutics14030620

By:

Tanna, Rakshit S.;
Nguyen, James T.;
Hadi, Deena L.;
Manwill, Preston K.;
Flores-Bocanegra, Laura;
Layton, Matthew E.;
White, John R.;
Cech, Nadja B.;
Oberlies, Nicholas H.;
Rettie, Allan E.;
Thummel, Kenneth E.;
Paine, Mary F.

Publication type:

Article

Clinical Assessment of the Drug Interaction Potential of the Psychotropic Natural Product Kratom.

Published in:

Clinical Pharmacology & Therapeutics, 2023, v. 113, n. 6, p. 1315, doi. 10.1002/cpt.2891

By:

Tanna, Rakshit S.;
Nguyen, James T.;
Hadi, Deena L.;
Layton, Matthew E.;
White, John R.;
Cech, Nadja B.;
Oberlies, Nicholas H.;
Rettie, Allan E.;
Thummel, Kenneth E.;
Paine, Mary F.

Publication type:

Article

Chemical synthesis, absolute configuration, and stereochemistry of formation of 10-hydroxywarfarin: A major oxidative metabolite of (+)-(r)-warfarin from hepatic microsomal preparations.

Published in:

Chirality, 1990, v. 2, n. 2, p. 96, doi. 10.1002/chir.530020207

By:

Lawrence, Ross F.;
Rettie, Allan E.;
Eddy, A. Craig;
Trager, William F.

Publication type:

Article

Generation and Characterization of a Cyp4b1 Null Mouse and the Role of CYP4B1 in the Activation and Toxicity of Ipomeanol.

Published in:

Toxicological Sciences, 2013, v. 134, n. 2, p. 243, doi. 10.1093/toxsci/kft123

By:

Parkinson, Oliver T.;
Liggitt, H. Denny;
Rettie, Allan E.;
Kelly, Edward J.

Publication type:

Article

Identification, Replication, and Functional Fine-Mapping of Expression Quantitative Trait Loci in Primary Human Liver Tissue.

Published in:

PLoS Genetics, 2011, v. 7, n. 5, p. 1, doi. 10.1371/journal.pgen.1002078

By:

Innocenti, Federico;
Cooper, Gregory M.;
Stanaway, Ian B.;
Gamazon, Eric R.;
Smith, Joshua D.;
Mirkov, Snezana;
Ramirez, Jacqueline;
Liu, Wanqing;
Lin, Yvonne S.;
Moloney, Cliona;
Aldred, Shelly Force;
Trinklein, Nathan D.;
Schuetz, Erin;
Nickerson, Deborah A.;
Thummel, Ken E.;
Rieder, Mark J.;
Rettie, Allan E.;
Ratain, Mark J.;
Cox, Nancy J.;
Brown, Christopher D.

Publication type:

Article