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1536. Population Pharmacokinetic Analysis of Baloxavir Morboxil, a Cap-Dependent Endonuclease Inhibitor, in Adult and Adolescent Healthy Subjects and Influenza Patients and Exposure-Response Relationships in the Patients at High-Risk of Influenza Complications
- Published in:
- Open Forum Infectious Diseases, 2019, v. 6, p. S559, doi. 10.1093/ofid/ofz360.1400
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- Publication type:
- Article
Correction to: A phase III randomized trial of gantenerumab in prodromal Alzheimer's disease.
- Published in:
- 2018
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- Publication type:
- Correction Notice
A phase III randomized trial of gantenerumab in prodromal Alzheimer's disease.
- Published in:
- Alzheimer's Research & Therapy, 2017, v. 9, p. 1, doi. 10.1186/s13195-017-0318-y
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- Publication type:
- Article
Item Response Theory as an Efficient Tool to Describe a Heterogeneous Clinical Rating Scale in De Novo Idiopathic Parkinson's Disease Patients.
- Published in:
- Pharmaceutical Research, 2017, v. 34, n. 10, p. 2109, doi. 10.1007/s11095-017-2216-1
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- Publication type:
- Article
Comparison of Model Averaging and Model Selection in Dose Finding Trials Analyzed by Nonlinear Mixed Effect Models.
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- AAPS Journal, 2018, v. 20, n. 3, p. 1, doi. 10.1208/s12248-018-0205-x
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- Publication type:
- Article
Ciprofloxacin Dosage and Emergence of Resistance in Human Commensal Bacteria.
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- Journal of Infectious Diseases, 2009, v. 200, n. 3, p. 390, doi. 10.1086/600122
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- Publication type:
- Article
A Pharmacokinetics–Time to Alleviation of Symptoms Model to Support Extrapolation of Baloxavir Marboxil Clinical Efficacy in Different Ethnic Groups with Influenza A or B.
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- Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 2, p. 372, doi. 10.1002/cpt.2648
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- Publication type:
- Article
Disease Modeling and Model‐Based Meta‐Analyses to Define a New Direction for a Phase III Program of Gantenerumab in Alzheimer's Disease.
- Published in:
- Clinical Pharmacology & Therapeutics, 2022, v. 111, n. 4, p. 857, doi. 10.1002/cpt.2535
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- Publication type:
- Article
Simulation‐based evaluation of the Pharmpy Automatic Model Development tool for population pharmacokinetic modeling in early clinical drug development.
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- CPT: Pharmacometrics & Systems Pharmacology, 2024, v. 13, n. 10, p. 1707, doi. 10.1002/psp4.13213
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- Article
Population pharmacokinetics and pharmacodynamics of enoxaparin in unstable angina and non-ST-segment elevation myocardial infarction.
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- British Journal of Clinical Pharmacology, 2003, v. 56, n. 4, p. 407, doi. 10.1046/j.1365-2125.2003.01904.x
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- Publication type:
- Article
Fisher information matrix for nonlinear mixed effects multiple response models: Evaluation of the appropriateness of the first order linearization using a pharmacokinetic/pharmacodynamic model.
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- Statistics in Medicine, 2009, v. 28, n. 14, p. 1940, doi. 10.1002/sim.3573
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- Publication type:
- Article
Design in nonlinear mixed effects models: Optimization using the Fedorov-Wynn algorithm and power of the Wald test for binary covariates.
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- Statistics in Medicine, 2007, v. 26, n. 28, p. 5162, doi. 10.1002/sim.2910
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- Publication type:
- Article
Fisher information matrix for non-linear mixed-effects models: evaluation and application for optimal design of enoxaparin population pharmacokinetics.
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- Statistics in Medicine, 2002, v. 21, n. 18, p. 2623, doi. 10.1002/sim.1041
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- Publication type:
- Article
Exposure–Bleeding Count Modeling of Emicizumab for the Prophylaxis of Bleeding in Persons with Hemophilia A with/Without Inhibitors Against Factor VIII.
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- Clinical Pharmacokinetics, 2021, v. 60, n. 7, p. 931, doi. 10.1007/s40262-021-01006-0
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- Publication type:
- Article
Population Pharmacokinetic Analysis and Exploratory Exposure–Bleeding Rate Relationship of Emicizumab in Adult and Pediatric Persons with Hemophilia A.
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- Clinical Pharmacokinetics, 2020, v. 59, n. 12, p. 1611, doi. 10.1007/s40262-020-00904-z
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- Publication type:
- Article
Using exploratory pharmacokinetic and pharmacodynamic analyses to predict the probability of flu‐like symptoms in healthy volunteers and patients with chronic hepatitis B treated with the toll‐like receptor 7 agonist ruzotolimod.
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- CTS: Clinical & Translational Science, 2024, v. 17, n. 8, p. 1, doi. 10.1111/cts.13896
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- Publication type:
- Article
Pharmacokinetics, safety, and simulated efficacy of an influenza treatment, baloxavir marboxil, in Chinese individuals.
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- CTS: Clinical & Translational Science, 2022, v. 15, n. 5, p. 1196, doi. 10.1111/cts.13237
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- Publication type:
- Article
Risk factors for Enterobacteriaceae bacteremia after liver transplantation.
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- Transplant International, 2008, v. 21, n. 8, p. 755, doi. 10.1111/j.1432-2277.2008.00673.x
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- Publication type:
- Article
cLRT-Mod: An efficient methodology for pharmacometric model-based analysis of longitudinal phase II dose finding studies under model uncertainty.
- Published in:
- 2021
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- Publication type:
- journal article
Automated Ankle-Brachial Pressure Index Measurement by Clinical Staff for Peripheral Arterial Disease Diagnosis in Nondiabetic and Diabetic Patients.
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- Diabetes Care, 2009, v. 32, n. 7, p. 1231, doi. 10.2337/dc08-2230
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- Publication type:
- Article
Prediction of Shrinkage of Individual Parameters Using the Bayesian Information Matrix in Non-Linear Mixed Effect Models with Evaluation in Pharmacokinetics.
- Published in:
- Pharmaceutical Research, 2013, v. 30, n. 9, p. 2355, doi. 10.1007/s11095-013-1079-3
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- Publication type:
- Article