OpenURL Connection Search

Select item for more details and to access through your institution.

A subset of 50 secretory granules in close contact with L-type Ca2+ channels accounts for first-phase insulin secretion in mouse beta-cells.
Published in:
2002
By:
- Barg, Sebastian;
- Eliasson, Lena;
- Renström, Erik;
- Rorsman, Patrik;
- Renström, Erik
Publication type:
journal article
Sulfonylurea-mediated stimulation of insulin exocytosis via an ATP-sensitive K+ channel-independent action.
Published in:
2002
By:
- Renström, Erik;
- Barg, Sebastian;
- Thévenod, Frank;
- Rorsman, Patrik;
- Renström, Erik;
- Thévenod, Frank
Publication type:
journal article
A critical role of the mechanosensor PIEZO1 in glucose-induced insulin secretion in pancreatic β-cells.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-31103-y
By:
- Ye, Yingying;
- Barghouth, Mohammad;
- Dou, Haiqiang;
- Luan, Cheng;
- Wang, Yongzhi;
- Karagiannopoulos, Alexandros;
- Jiang, Xiaoping;
- Krus, Ulrika;
- Fex, Malin;
- Zhang, Quan;
- Eliasson, Lena;
- Rorsman, Patrik;
- Zhang, Enming;
- Renström, Erik
Publication type:
Article
Impaired insulin secretion and glucose tolerance in ß cell-selective CaV1.2 Ca2+ channel null mice.
Published in:
EMBO Journal, 2003, v. 22, n. 15, p. 3844, doi. 10.1093/emboj/cdg389
By:
- Schulla, Verena;
- Renström, Erik;
- Feil, Robert;
- Feil, Susanne;
- Franklin, Isobel;
- Gjinovci, Aslian;
- Xing-Jun Jing;
- Laux, Dirk;
- Lundquist, Ingmar;
- Magnuson, Mark A.;
- Obermüller, Stefanie;
- Olofsson, Charlotta S.;
- Salehi, Albert;
- Wendt, Anna;
- Klugbauer, Norbert;
- Wollheim, Claes B.;
- Rorsman, Patrik;
- Hofmann, Franz
Publication type:
Article
CaV2.3 calcium channels control second-phase insulin release.
Published in:
Journal of Clinical Investigation, 2005, v. 115, n. 1, p. 146, doi. 10.1172/JCI200522518
By:
- Xingjun Jing;
- Dai-Qing Li;
- Olofsson, Charlotta S.;
- Salehi, Albert;
- Surve, Vikas V.;
- Caballero, José;
- Ivarsson, Rosita;
- Lundquist, Ingmar;
- Pereverzev, Alexey;
- Schneider, Toni;
- Rorsman, Patrik;
- Renström, Erik
Publication type:
Article
CaM kinase II-dependent mobilization of secretory granules underlies acetylcholine-induced stimulation of exocytosis in mouse pancreatic B-cells.
Published in:
Journal of Physiology, 1999, v. 518, n. 3, p. 745, doi. 10.1111/j.1469-7793.1999.0745p.x
By:
- Gromada, Jesper;
- Høy, Marianne;
- Renström, Erik;
- Bokvist, Krister;
- Eliasson, Lena;
- Göpel, Sven;
- Rorsman, Patrik
Publication type:
Article
The human serum protein C4b-binding protein inhibits pancreatic IAPP-induced inflammasome activation.
Published in:
Diabetologia, 2017, v. 60, n. 8, p. 1522, doi. 10.1007/s00125-017-4286-3
By:
- Kulak, Klaudia;
- Westermark, Gunilla;
- Papac-Milicevic, Nikolina;
- Renström, Erik;
- Blom, Anna;
- King, Ben
Publication type:
Article
Glioma Cell Proliferation Controlled by ERK Activity-Dependent Surface Expression of PDGFRA.
Published in:
PLoS ONE, 2014, v. 9, n. 1, p. 1, doi. 10.1371/journal.pone.0087281
By:
- Chen, Dongfeng;
- Zuo, Duo;
- Luan, Cheng;
- Liu, Min;
- Na, Manli;
- Ran, Liang;
- Sun, Yingyu;
- Persson, Annette;
- Englund, Elisabet;
- Salford, Leif G.;
- Renström, Erik;
- Fan, Xiaolong;
- Zhang, Enming
Publication type:
Article
Eukaryotic Translation Initiation Factor 3 Subunit E Controls Intracellular Calcium Homeostasis by Regulation of Cav1.2 Surface Expression
Published in:
PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0064462
By:
- Buda, Pawel;
- Reinbothe, Thomas;
- Nagaraj, Vini;
- Mahdi, Taman;
- Luan, Cheng;
- Tang, Yunzhao;
- Axelsson, Annika S.;
- Li, Daiqing;
- Rosengren, Anders H.;
- Renström, Erik;
- Zhang, Enming
Publication type:
Article
The Adult Human Brain Harbors Multipotent Perivascular Mesenchymal Stem Cells.
Published in:
PLoS ONE, 2012, v. 7, n. 4, p. 1, doi. 10.1371/journal.pone.0035577
By:
- Paul, Gesine;
- Özen, Ilknur;
- Christophersen, Nicolaj S.;
- Reinbothe, Thomas;
- Bengzon, Johan;
- Visse, Edward;
- Jansson, Katarina;
- Dannaeus, Karin;
- Henriques-Oliveira, Catarina;
- Roybon, Laurent;
- Anisimov, Sergey V.;
- Renström, Erik;
- Svensson, Mikael;
- Haegerstrand, Anders;
- Brundin, Patrik
Publication type:
Article
Transcriptional analysis of islets of Langerhans from organ donors of different ages.
Published in:
PLoS ONE, 2021, v. 16, n. 3, p. 1, doi. 10.1371/journal.pone.0247888
By:
- Seiron, Peter;
- Stenwall, Anton;
- Hedin, Anders;
- Granlund, Louise;
- Esguerra, Jonathan Lou S.;
- Volkov, Petr;
- Renström, Erik;
- Korsgren, Olle;
- Lundberg, Marcus;
- Skog, Oskar
Publication type:
Article
Perchlorate stimulates insulin secretion by shifting the gating of L-type Ca2+ currents in mouse pancreatic B-cells towards negative potentials.
Published in:
Pflügers Archiv: European Journal of Physiology, 2001, v. 441, n. 5, p. 587, doi. 10.1007/s004240000426
By:
- Larsson-Nyrén, Gerd;
- Sehlin, Janove;
- Rorsman, Patrik;
- Renström, Erik
Publication type:
Article
Islet Gene View--a tool to facilitate islet research.
Published in:
Life Science Alliance, 2022, v. 5, n. 12, p. 1, doi. 10.26508/lsa.202201376
By:
- Asplund, Olof;
- Storm, Petter;
- Chandra, Vikash;
- Hatem, Gad;
- Ottosson-Laakso, Emilia;
- Mansour-Aly, Dina;
- Krus, Ulrika;
- Ibrahim, Hazem;
- Ahlqvist, Emma;
- Tuomi, Tiinamaija;
- Renström, Erik;
- Korsgren, Olle;
- Wierup, Nils;
- Ibberson, Mark;
- Solimena, Michele;
- Marchetti, Piero;
- Wollheim, Claes;
- Artner, Isabella;
- Mulder, Hindrik;
- Hansson, Ola
Publication type:
Article
R-type Ca2+-channel-evoked CICR regulates glucose-induced somatostatin secretion.
Published in:
Nature Cell Biology, 2007, v. 9, n. 4, p. 453, doi. 10.1038/ncb1563
By:
- Quan Zhang;
- Bengtsson, Martin;
- Partridge, Chris;
- Salehi, Albert;
- Braun, Matthias;
- Cox, Roger;
- Eliasson, Lena;
- Johnson, Paul R. V.;
- Renström, Erik;
- Schneider, Toni;
- Berggren, Per-Olof;
- Göpel, Sven;
- Ashcroft, Frances M.;
- Rorsman, Patrik
Publication type:
Article
A cryptic non-GPI-anchored cytosolic isoform of CD59 controls insulin exocytosis in pancreatic β-cells by interaction with SNARE proteins.
Published in:
FASEB Journal, 2019, v. 33, n. 11, p. 12425, doi. 10.1096/fj.201901007R
By:
- Golec, Ewelina;
- Rosberg, Rebecca;
- Enming Zhang;
- Renström, Erik;
- Blom, Anna M.;
- King, Ben C.
Publication type:
Article
Myosin 5a Controls Insulin Granule Recruitment During Late-Phase Secretion.
Published in:
Traffic, 2005, v. 6, n. 11, p. 1027, doi. 10.1111/j.1600-0854.2005.00342.x
By:
- Ivarsson, Rosita;
- Jing, Xingjun;
- Waselle, Laurent;
- Regazzi, Romano;
- Renström, Erik
Publication type:
Article
Temperature-Sensitive Random Insulin Granule Diffusion is a Prerequisite for Recruiting Granules for Release.
Published in:
Traffic, 2004, v. 5, n. 10, p. 750, doi. 10.1111/j.1600-0854.2004.00216.x
By:
- Ivarsson, Rosita;
- Obermüller, Stefanie;
- Rutter, Guy A.;
- Galvanovskis, Juris;
- Renström, Erik
Publication type:
Article
Genotype-based treatment of type 2 diabetes with an α2A-adrenergic receptor antagonist.
Published in:
Science Translational Medicine, 2014, v. 6, n. 257, p. 1, doi. 10.1126/scitranslmed.3009934
By:
- Yunzhao Tang;
- Axelsson, Annika S.;
- Spégel, Peter;
- Andersson, Lotta E.;
- Mulder, Hindrik;
- Groop, Leif C.;
- Renström, Erik;
- Rosengren, Anders H.
Publication type:
Article
Rapid ATP-Dependent Priming of Secretory Granules Precedes Ca2+ -Induced Exocytosis in Mouse Pancreatic B-Cells.
Published in:
Journal of Physiology, 1997, v. 503, n. 2, p. 399, doi. 10.1111/j.1469-7793.1997.399bh.x
By:
- Eliasson, Lena;
- Renström, Erik;
- Ding, Wei-Guang;
- Proks, Peter;
- Rorsman, Patrik
Publication type:
Article
TCF7L2 is a master regulator of insulin production and processing.
Published in:
Human Molecular Genetics, 2014, v. 23, n. 24, p. 6419, doi. 10.1093/hmg/ddu359
By:
- Zhou, Yuedan;
- Park, Soo-Young;
- Su, Jing;
- Bailey, Kathleen;
- Ottosson-Laakso, Emilia;
- Shcherbina, Liliya;
- Oskolkov, Nikolay;
- Zhang, Enming;
- Thevenin, Thomas;
- Fadista, João;
- Bennet, Hedvig;
- Vikman, Petter;
- Wierup, Nils;
- Fex, Malin;
- Rung, Johan;
- Wollheim, Claes;
- Nobrega, Marcelo;
- Renström, Erik;
- Groop, Leif;
- Hansson, Ola
Publication type:
Article
Survival of pancreatic beta cells is partly controlled by a TCF7L2-p53-p53INP1-dependent pathway.
Published in:
Human Molecular Genetics, 2012, v. 21, n. 1, p. 196, doi. 10.1093/hmg/ddr454
By:
- Zhou, Yuedan;
- Zhang, Enming;
- Berggreen, Christine;
- Jing, Xingjun;
- Osmark, Peter;
- Lang, Stefan;
- Cilio, Corrado M.;
- Göransson, Olga;
- Groop, Leif;
- Renström, Erik;
- Hansson, Ola
Publication type:
Article
MAFA and MAFB regulate exocytosis‐related genes in human β‐cells.
Published in:
Acta Physiologica, 2022, v. 234, n. 2, p. 1, doi. 10.1111/apha.13761
By:
- Cataldo, Luis Rodrigo;
- Singh, Tania;
- Achanta, Kavya;
- Bsharat, Sara;
- Prasad, Rashmi B.;
- Luan, Cheng;
- Renström, Erik;
- Eliasson, Lena;
- Artner, Isabella
Publication type:
Article
Novel Congenic Strain of the Goto-Kakizaki Rat Reveals Nuclear-Mitochondrial Interactions in Type 2 Diabetes.
Published in:
Diabetes, 2007, v. 56, p. A305
By:
- Abhyankar, Avinash;
- Rosengren, Anders;
- Berger, Karin;
- Renström, Erik;
- Degerman, Eva;
- Tonolo, Giancarlo;
- Luthman, Holger
Publication type:
Article
Separately Inherited Defects in Insulin Exocytosis and β-Cell Glucose Metabolism Contribute to Type 2 Diabetes.
Published in:
Diabetes, 2006, v. 55, n. 12, p. 3494, doi. 10.2337/db06-0796
By:
- Granhall, Charlotte;
- Rosengren, Anders H.;
- Renström, Erik;
- Luthman, Holger
Publication type:
Article
Redox control of exocytosis: regulatory role of NADPH, thioredoxin, and glutaredoxin.
Published in:
2005
By:
- Ivarsson R;
- Quintens R;
- Dejonghe S;
- Tsukamoto K;
- in't Veld P;
- Renström E;
- Schuit FC;
- Ivarsson, Rosita;
- Quintens, Roel;
- Dejonghe, Sandra;
- Tsukamoto, Katsura;
- in 't Veld, Peter;
- Renström, Erik;
- Schuit, Frans C
Publication type:
journal article
Redox Control of Exocytosis.
Published in:
Diabetes, 2005, v. 54, n. 7, p. 2132, doi. 10.2337/diabetes.54.7.2132
By:
- Ivarsson, Rosita;
- Quintens, Roel;
- Dejonghe, Sandra;
- Tsukamoto, Katsura;
- in 't Veld, Peter;
- Renström, Erik;
- Schuit, Frans C.
Publication type:
Article
Glucagon-Like Peptide I and Glucose-Dependent Insulinotropic Polypeptide Stimulate Ca2+ -Induced Secretion in Rat α-Cells by a Protein Kinase A-Mediated Mechanism.
Published in:
Diabetes, 1997, v. 46, n. 5, p. 792, doi. 10.2337/diab.46.5.792
By:
- Wei-Guang Ding;
- Renström, Erik;
- Rorsman, Patrik;
- Buschard, Karsten;
- Gromada, Jesper
Publication type:
Article
Glucagon-like peptide I increases cytoplasmic calcium in insulin-secreting beta TC3-cells by enhancement of intracellular calcium mobilization.
Published in:
1995
By:
- Gromada, Jesper;
- Dissing, Steen;
- Bokvist, Krister;
- Renström, Erik;
- Frøkjær-Jensen, Jørgen;
- Wulff, Birgitte S.;
- Rorsman, Patrik;
- Gromada, J;
- Dissing, S;
- Bokvist, K;
- Renström, E;
- Frøkjaer-Jensen, J;
- Wulff, B S;
- Rorsman, P
Publication type:
journal article
The calcium channel subunit gamma-4 is regulated by MafA and necessary for pancreatic beta-cell specification.
Published in:
Communications Biology, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42003-019-0351-4
By:
- Luan, Cheng;
- Ye, Yingying;
- Singh, Tania;
- Barghouth, Mohammad;
- Eliasson, Lena;
- Artner, Isabella;
- Zhang, Enming;
- Renström, Erik
Publication type:
Article
The Calcium Channel Subunit Gamma-4 as a Novel Regulator of MafA in Pancreatic Beta-Cell Controls Glucose Homeostasis.
Published in:
Biomedicines, 2022, v. 10, n. 4, p. 770, doi. 10.3390/biomedicines10040770
By:
- Wu, Rui;
- Karagiannopoulos, Alexandros;
- Eliasson, Lena;
- Renström, Erik;
- Luan, Cheng;
- Zhang, Enming
Publication type:
Article
Epigenome-Wide Histone Acetylation Changes in Peripheral Blood Mononuclear Cells in Patients with Type 2 Diabetes and Atherosclerotic Disease.
Published in:
Biomedicines, 2021, v. 9, n. 12, p. 1908, doi. 10.3390/biomedicines9121908
By:
- Bompada, Pradeep;
- Goncalves, Isabel;
- Wu, Chuanyan;
- Gao, Rui;
- Sun, Jiangming;
- Mir, Bilal Ahmad;
- Luan, Cheng;
- Renström, Erik;
- Groop, Leif;
- Weng, Jianping;
- Hansson, Ola;
- Edsfeldt, Andreas;
- De Marinis, Yang
Publication type:
Article
The R6/2 transgenic mouse model of Huntington's disease develops diabetes due to deficient β-cell mass and exocytosis.
Published in:
Human Molecular Genetics, 2005, v. 14, n. 5, p. 565
By:
- Björkqvist, Maria;
- Fex, Malin;
- Renström, Erik;
- Wierup, Nils;
- Petersén, Åsa;
- Gil, Joana;
- Bacos, Karl;
- Popovic, Natalija;
- Li, Jia-Yi;
- Sundler, Frank;
- Brundin, Patrik;
- Mulder, Hindrik
Publication type:
Article
MafA Expression Preserves Immune Homeostasis in Human and Mouse Islets.
Published in:
Genes, 2018, v. 9, n. 12, p. 644, doi. 10.3390/genes9120644
By:
- Singh, Tania;
- Sarmiento, Luis;
- Luan, Cheng;
- Prasad, Rashmi B.;
- Johansson, Jenny;
- Cataldo, Luis R.;
- Renström, Erik;
- Soneji, Shamit;
- Cilio, Corrado;
- Artner, Isabella
Publication type:
Article
Why Treatment Fails in Type 2 Diabetes.
Published in:
PLoS Medicine, 2008, v. 5, n. 10, p. 1426, doi. 10.1371/journal.pmed.0050215
By:
- Rosengren, Anders;
- Xingjun Jing;
- Eliasson, Lena;
- Renström, Erik
Publication type:
Article
Regulation of Nuclear Receptor Interacting Protein 1 (NRIP1) Gene Expression in Response to Weight Loss and Exercise in Humans.
Published in:
2017
By:
- Marinis, Yang;
- Sun, Jiangming;
- Bompada, Pradeep;
- Domènech Omella, Judit;
- Luan, Cheng;
- Halu, Arda;
- Renström, Erik;
- Sharma, Amitabh;
- Ridderstråle, Martin
Publication type:
journal article
A circular RNA generated from an intron of the insulin gene controls insulin secretion.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-19381-w
By:
- Stoll, Lisa;
- Rodríguez-Trejo, Adriana;
- Guay, Claudiane;
- Brozzi, Flora;
- Bayazit, Mustafa Bilal;
- Gattesco, Sonia;
- Menoud, Véronique;
- Sobel, Jonathan;
- Marques, Ana Claudia;
- Venø, Morten Trillingsgaard;
- Esguerra, Jonathan Lou S.;
- Barghouth, Mohammad;
- Suleiman, Mara;
- Marselli, Lorella;
- Kjems, Jørgen;
- Eliasson, Lena;
- Renström, Erik;
- Bouzakri, Karim;
- Pinget, Michel;
- Marchetti, Piero
Publication type:
Article
Molecular Function of TCF7L2: Consequences of TCF7L2 Splicing for Molecular Function and Risk for Type 2 Diabetes.
Published in:
Current Diabetes Reports, 2010, v. 10, n. 6, p. 444, doi. 10.1007/s11892-010-0149-8
By:
- Hansson, Ola;
- Zhou, Yuedan;
- Renström, Erik;
- Osmark, Peter
Publication type:
Article
Loss of α2δ-1 Calcium Channel Subunit Function Increases the Susceptibility for Diabetes.
Published in:
2017
By:
- Mastrolia, Vincenzo;
- Flucher, Sylvia M.;
- Obermair, Gerald J.;
- Drach, Mathias;
- Hofer, Helene;
- Renström, Erik;
- Schwartz, Arnold;
- Striessnig, Jörg;
- Flucher, Bernhard E.;
- Tuluc, Petronel
Publication type:
journal article
Effects of common genetic variants associated with type 2 diabetes and glycemic traits on α- and β-cell function and insulin action in humans.
Published in:
2013
By:
- Jonsson, Anna;
- Ladenvall, Claes;
- Ahluwalia, Tarunveer Singh;
- Kravic, Jasmina;
- Krus, Ulrika;
- Taneera, Jalal;
- Isomaa, Bo;
- Tuomi, Tiinamaija;
- Renström, Erik;
- Groop, Leif;
- Lyssenko, Valeriya
Publication type:
journal article
Effects of Common Genetic Variants Associated With Type 2 Diabetes and Glycemic Traits on α- and β-Cell Function and Insulin Action in Humans.
Published in:
Diabetes, 2013, v. 62, n. 8, p. 2978, doi. 10.2337/db12-1627
By:
- Jonsson, Anna;
- Ladenvall, Claes;
- Ahluwalia, Tarunveer Singh;
- Kravic, Jasmina;
- Krus, Ulrika;
- Taneera, Jalal;
- Isomaa, Bo;
- Tuomi, Tiinamaija;
- Renström, Erik;
- Groop, Leif;
- Lyssenko, Valeriya
Publication type:
Article

Found: 40