Works by Renna, Maurizio

Results: 25

Small HSPs at the crossroad between protein aggregation, autophagy and unconventional secretion: clinical implications and potential therapeutic opportunities in the context of neurodegenerative diseases.

Published in:

Frontiers in Cell & Developmental Biology, 2025, p. 1, doi. 10.3389/fcell.2025.1538377

By:

Bonavita, Raffaella;
Vitale, Fulvia;
Verdicchio, Luigi Vittorio;
Williams, Sarah V.;
Caporaso, Maria Gabriella;
Fleming, Angeleen;
Renna, Maurizio

Publication type:

Article

Commentary: Overcoming mTOR resistance mutations with a new-generation mTOR inhibitor.

Published in:

2016

By:

Renna, Maurizio;
Vigneri, Paolo Giovanni;
Cardone, Luca

Publication type:

Opinion

PERK-Mediated Unfolded Protein Response Activation and Oxidative Stress in PARK20 Fibroblasts.

Published in:

Frontiers in Neuroscience, 2019, p. N.PAG, doi. 10.3389/fnins.2019.00673

By:

Amodio, Giuseppina;
Moltedo, Ornella;
Fasano, Dominga;
Zerillo, Lucrezia;
Oliveti, Marco;
Di Pietro, Paola;
Faraonio, Raffaella;
Barone, Paolo;
Pellecchia, Maria Teresa;
De Rosa, Anna;
De Michele, Giuseppe;
Polishchuk, Elena;
Polishchuk, Roman;
Bonifati, Vincenzo;
Nitsch, Lucio;
Pierantoni, Giovanna Maria;
Renna, Maurizio;
Criscuolo, Chiara;
Paladino, Simona;
Remondelli, Paolo

Publication type:

Article

A method for the analysis of the oligomerization profile of the Huntington’s disease-associated, aggregation-prone mutant huntingtin protein by isopycnic ultracentrifugation.

Published in:

Frontiers in Molecular Biosciences, 2024, p. 1, doi. 10.3389/fmolb.2024.1420691

By:

Bonavita, Raffaella;
Di Martino, Rosaria;
Cortone, Giuseppe;
Prodomo, Antonello;
Di Gennaro, Mariagrazia;
Scerra, Gianluca;
Panico, Valentino;
Nuzzo, Silvia;
Salvatore, Marco;
Williams, Sarah V.;
Vitale, Fulvia;
Caporaso, Maria Gabriella;
D’Agostino, Massimo;
Pisani, Francesca M.;
Fleming, Angeleen;
Renna, Maurizio

Publication type:

Article

Contact inhibition controls cell survival and proliferation via YAP/TAZ-autophagy axis.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-05388-x

By:

Pavel, Mariana;
Renna, Maurizio;
Park, So Jung;
Menzies, Fiona M.;
Ricketts, Thomas;
Füllgrabe, Jens;
Ashkenazi, Avraham;
Frake, Rebecca A.;
Lombarte, Alejandro Carnicer;
Bento, Carla F.;
Franze, Kristian;
Rubinsztein, David C.

Publication type:

Article

Functional drug screening reveals anticonvulsants as enhancers of mTOR-independent autophagic killing of Mycobacterium tuberculosis through inositol depletion.

Published in:

EMBO Molecular Medicine, 2015, v. 7, n. 2, p. 127, doi. 10.15252/emmm.201404137

By:

Schiebler, Mark;
Brown, Karen;
Hegyi, Krisztina;
Newton, Sandra M;
Renna, Maurizio;
Hepburn, Lucy;
Klapholz, Catherine;
Coulter, Sarah;
Obregón‐Henao, Andres;
Henao Tamayo, Marcela;
Basaraba, Randall;
Kampmann, Beate;
Henry, Katherine M;
Burgon, Joseph;
Renshaw, Stephen A;
Fleming, Angeleen;
Kay, Robert R;
Anderson, Karen E;
Hawkins, Phillip T;
Ordway, Diane J

Publication type:

Article

The Endoplasmic Reticulum Unfolded Protein Response in Neurodegenerative Disorders and Its Potential Therapeutic Significance.

Published in:

Frontiers in Molecular Neuroscience, 2017, p. 1, doi. 10.3389/fnmol.2017.00187

By:

Remondelli, Paolo;
Renna, Maurizio

Publication type:

Article

Autophagy induction reduces mutant ataxin-3 levels and toxicity in a mouse model of spinocerebellar ataxia type 3.

Published in:

Brain: A Journal of Neurology, 2010, v. 133, n. 1, p. 93, doi. 10.1093/brain/awp292

By:

Menzies, Fiona M.;
Huebener, Jeannette;
Renna, Maurizio;
Bonin, Michael;
Riess, Olaf;
Rubinsztein, David C.

Publication type:

Article

IBtkα Activates the β-Catenin-Dependent Transcription of MYC through Ubiquitylation and Proteasomal Degradation of GSK3β in Cancerous B Cells.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 4, p. 2044, doi. 10.3390/ijms23042044

By:

Vecchio, Eleonora;
Nisticò, Nancy;
Golino, Gaetanina;
Iaccino, Enrico;
Maisano, Domenico;
Mimmi, Selena;
Aloisio, Annamaria;
Renna, Maurizio;
Avagliano, Angelica;
Arcucci, Alessandro;
Fiume, Giuseppe;
Quinto, Ileana

Publication type:

Article

Revisiting Bacterial Ubiquitin Ligase Effectors: Weapons for Host Exploitation.

Published in:

International Journal of Molecular Sciences, 2018, v. 19, n. 11, p. 3576, doi. 10.3390/ijms19113576

By:

Pisano, Antonio;
Albano, Francesco;
Vecchio, Eleonora;
Renna, Maurizio;
Scala, Giuseppe;
Quinto, Ileana;
Fiume, Giuseppe

Publication type:

Article

YAP and TAZ Mediators at the Crossroad between Metabolic and Cellular Reprogramming.

Published in:

Metabolites (2218-1989), 2021, v. 11, n. 3, p. 154, doi. 10.3390/metabo11030154

By:

Di Benedetto, Giorgia;
Parisi, Silvia;
Russo, Tommaso;
Passaro, Fabiana;
Fiume, Giuseppe;
Palmieri, Camillo;
Renna, Maurizio;
D'Agostino, Massimo

Publication type:

Article

CCT complex restricts neuropathogenic protein aggregation via autophagy.

Published in:

Nature Communications, 2016, v. 7, n. 12, p. 13821, doi. 10.1038/ncomms13821

By:

Pavel, Mariana;
Imarisio, Sara;
Menzies, Fiona M.;
Jimenez-Sanchez, Maria;
Siddiqi, Farah H.;
Wu, Xiaoting;
Renna, Maurizio;
O'Kane, Cahir J.;
Crowther, Damian C.;
Rubinsztein, David C.

Publication type:

Article

Transcriptional regulation of Annexin A2 promotes starvation-induced autophagy.

Published in:

Nature Communications, 2015, v. 6, n. 8, p. 8045, doi. 10.1038/ncomms9045

By:

Moreau, Kevin;
Ghislat, Ghita;
Hochfeld, Warren;
Renna, Maurizio;
Zavodszky, Eszter;
Runwal, Gautam;
Puri, Claudia;
Lee, Shirley;
Siddiqi, Farah;
Menzies, Fiona M.;
Ravikumar, Brinda;
Rubinsztein, David C.

Publication type:

Article

XIAP and cIAP1 amplifications induce Beclin 1-dependent autophagy through NFκB activation.

Published in:

Human Molecular Genetics, 2015, v. 24, n. 10, p. 2899, doi. 10.1093/hmg/ddv052

By:

Fang Lin;
Ghislat, Ghita;
Shouqing Luo;
Renna, Maurizio;
Siddiqi, Farah;
Rubinsztein, David C.

Publication type:

Article

IGF-1 receptor antagonism inhibits autophagy.

Published in:

Human Molecular Genetics, 2013, v. 22, n. 22, p. 4528, doi. 10.1093/hmg/ddt300

By:

Renna, Maurizio;
Bento, Carla F.;
Fleming, Angeleen;
Menzies, Fiona M.;
Siddiqi, Farah H.;
Ravikumar, Brinda;
Puri, Claudia;
Garcia-Arencibia, Moises;
Sadiq, Oana;
Corrochano, Silvia;
Carter, Sarah;
Brown, Steve D.M.;
Acevedo-Arozena, Abraham;
Rubinsztein, David C.

Publication type:

Article

α-Synuclein levels modulate Huntington's disease in mice.

Published in:

Human Molecular Genetics, 2012, v. 21, n. 23, p. 5237, doi. 10.1093/hmg/dds351

By:

Corrochano, Silvia;
Renna, Maurizio;
Carter, Sarah;
Chrobot, Nichola;
Kent, Rose;
Stewart, Michelle;
Cooper, Jason;
Brown, Steve D.M.;
Rubinsztein, David C.;
Acevedo-Arozena, Abraham

Publication type:

Article

α-Synuclein levels modulate Huntington's disease in mice.

Published in:

Human Molecular Genetics, 2012, v. 21, n. 3, p. 485, doi. 10.1093/hmg/ddr477

By:

Corrochano, Silvia;
Renna, Maurizio;
Carter, Sarah;
Chrobot, Nichola;
Kent, Rose;
Stewart, Michelle;
Cooper, Jason;
Brown, Steve D.M.;
Rubinsztein, David C.;
Acevedo-Arozena, Abraham

Publication type:

Article

Antioxidants can inhibit basal autophagy and enhance neurodegeneration in models of polyglutamine disease.

Published in:

Human Molecular Genetics, 2010, v. 19, n. 17, p. 3413, doi. 10.1093/hmg/ddq253

By:

Underwood, Benjamin R.;
Imarisio, Sara;
Fleming, Angeleen;
Rose, Claudia;
Krishna, Gauri;
Heard, Phoebe;
Quick, Marie;
Korolchuk, Viktor I.;
Renna, Maurizio;
Sarkar, Sovan;
García-Arencibia, Moisés;
O'Kane, Cahir J.;
Murphy, Michael P.;
Rubinsztein, David C.

Publication type:

Article

Rilmenidine attenuates toxicity of polyglutamine expansions in a mouse model of Huntington's disease.

Published in:

Human Molecular Genetics, 2010, v. 19, n. 11, p. 2144, doi. 10.1093/hmg/ddq093

By:

Rose, Claudia;
Menzies, Fiona M.;
Renna, Maurizio;
Acevedo-Arozena, Abraham;
Corrochano, Silvia;
Sadiq, Oana;
Brown, Steve D.;
Rubinsztein, David C.

Publication type:

Article

Insights into Thymus Development and Viral Thymic Infections.

Published in:

Viruses (1999-4915), 2019, v. 11, n. 9, p. 836, doi. 10.3390/v11090836

By:

Albano, Francesco;
Vecchio, Eleonora;
Renna, Maurizio;
Iaccino, Enrico;
Mimmi, Selena;
Caiazza, Carmen;
Arcucci, Alessandro;
Avagliano, Angelica;
Pagliara, Valentina;
Donato, Giuseppe;
Palmieri, Camillo;
Mallardo, Massimo;
Quinto, Ileana;
Fiume, Giuseppe

Publication type:

Article

Reducing <i>Igf-1r</i> Levels Leads To Paradoxical and Sexually Dimorphic Effects in HD Mice.

Published in:

PLoS ONE, 2014, v. 9, n. 8, p. 1, doi. 10.1371/journal.pone.0105595

By:

Corrochano, Silvia;
Renna, Maurizio;
Osborne, Georgina;
Carter, Sarah;
Stewart, Michelle;
May, Joel;
Bates, Gillian P.;
Brown, Steve D. M.;
Rubinsztein, David C.;
Acevedo-Arozena, Abraham

Publication type:

Article

Activation of Non-Canonical Autophagic Pathway through Inhibition of Non-Integrin Laminin Receptor in Neuronal Cells.

Published in:

Cells (2073-4409), 2022, v. 11, n. 3, p. 466, doi. 10.3390/cells11030466

By:

Limone, Adriana;
Veneruso, Iolanda;
Izzo, Antonella;
Renna, Maurizio;
Bonavita, Raffaella;
Piscitelli, Silvia;
Calì, Gaetano;
De Nicola, Sergio;
Riccio, Patrizia;
D'Argenio, Valeria;
Lavecchia, Antonio;
Sarnataro, Daniela

Publication type:

Article

ATG16L1 meets ATG9 in recycling endosomes.

Published in:

Autophagy, 2014, v. 10, n. 1, p. 182, doi. 10.4161/auto.27174

By:

Puri, Claudia;
Renna, Maurizio;
Figueira Bento, Carla;
Moreau, Kevin;
Rubinsztein, David C.

Publication type:

Article

α-synuclein levels affect autophagosome numbers in vivo and modulate Huntington disease pathology.

Published in:

Autophagy, 2012, v. 8, n. 3, p. 431, doi. 10.4161/auto.19259

By:

Corrochano, Silvia;
Renna, Maurizio;
Tomas-Zapico, Cristina;
Brown, Steve D.M.;
Lucas, Jose J;
Rubinsztein, David C.;
Acevedo-Arozena, Abraham

Publication type:

Article

α-Catenin levels determine direction of YAP/TAZ response to autophagy perturbation.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-21882-1

By:

Pavel, Mariana;
Park, So Jung;
Frake, Rebecca A.;
Son, Sung Min;
Manni, Marco M.;
Bento, Carla F.;
Renna, Maurizio;
Ricketts, Thomas;
Menzies, Fiona M.;
Tanasa, Radu;
Rubinsztein, David C.

Publication type:

Article