Works matching AU Remedi, Maria S.

Results: 39

Critical Role of Gap Junction Coupled KATP Channel Activity for Regulated Insulin Secretion.

Published in:

PLoS Biology, 2006, v. 4, n. 2, p. e26, doi. 10.1371/journal.pbio.0040026

By:

Rocheleau, Jonathan V.;
Remedi, Maria S.;
Granada, Butch;
Head, W. Steven;
Koster, Joseph C.;
Nichols, Colin G.;
Piston, David W.

Publication type:

Article

High‐fat diet prevents the development of autoimmune diabetes in NOD mice.

Published in:

Diabetes, Obesity & Metabolism, 2021, v. 23, n. 11, p. 2455, doi. 10.1111/dom.14486

By:

Clark, Amy L.;
Yan, Zihan;
Chen, Sophia X.;
Shi, Victoria;
Kulkarni, Devesha H.;
Diwan, Abhinav;
Remedi, Maria S.

Publication type:

Article

High‐fat‐diet‐induced remission of diabetes in a subset of KATP‐GOF insulin‐secretory‐deficient mice.

Published in:

Diabetes, Obesity & Metabolism, 2018, v. 20, n. 11, p. 2574, doi. 10.1111/dom.13423

By:

Yan, Zihan;
Shyr, Zeenat A.;
Fortunato, Manuela;
Welscher, Alecia;
Alisio, Mariana;
Martino, Michael;
Finck, Brian N.;
Conway, Hannah;
Remedi, Maria S.

Publication type:

Article

SGLT2 inhibitors therapy protects glucotoxicity-induced β-cell failure in a mouse model of human KATP-induced diabetes through mitigation of oxidative and ER stress.

Published in:

PLoS ONE, 2022, v. 17, n. 2, p. 1, doi. 10.1371/journal.pone.0258054

By:

Shyr, Zeenat A.;
Yan, Zihan;
Ustione, Alessandro;
Egan, Erin M.;
Remedi, Maria S.

Publication type:

Article

Preferential Gq signaling in diabetes: an electrical switch in incretin action and in diabetes progression?

Published in:

2020

By:

Nichols, Colin G.;
York, Nathaniel W.;
Remedi, Maria S.

Publication type:

journal article

Glibenclamide reverses cardiovascular abnormalities of Cantu syndrome driven by KATP channel overactivity.

Published in:

2020

By:

McClenaghan, Conor;
Yan Huang;
Zihan Yan;
Harter, Theresa M.;
Halabi, Carmen M.;
Chalk, Rod;
Kovacs, Attila;
van Haaften, Gijs;
Remedi, Maria S.;
Nichols, Colin G.;
Huang, Yan;
Yan, Zihan;
Harter, Theresa

Publication type:

journal article

Rpl13a small nucleolar RNAs regulate systemic glucose metabolism.

Published in:

2016

By:

Jiyeon Lee;
Harris, Alexis N.;
Holley, Christopher L.;
Mahadevan, Jana;
Pyles, Kelly D.;
Lavagnlno, Zeno;
Scherrer, David E.;
Hideji Fujiwara;
Sidhu, Rohini;
Jessie Zhang;
Ching-Cheng Huang, Stanley;
Piston, David W.;
Remedi, Maria S.;
Fumihlko Utano;
Ory, Daniel S.;
Schafer, Jean E.;
Lee, Jiyeon;
Lavagnino, Zeno;
Fujiwara, Hideji;
Zhang, Jessie

Publication type:

journal article

Remission of Severe Neonatal Diabetes With Very Early Sulfonylurea Treatment.

Published in:

2015

By:

Marshall, Bess A.;
Green, Rebecca P.;
Wambach, Jennifer;
White, Neil H.;
Remedi, Maria S.;
Nichols, Colin G.

Publication type:

Case Study

In vivo monitoring of intracellular Ca2+ dynamics in the pancreatic β-cells of zebrafish embryos.

Published in:

Islets, 2018, v. 10, n. 6, p. 221, doi. 10.1080/19382014.2018.1540234

By:

Lorincz, Reka;
Emfinger, Christopher H.;
Walcher, Andrea;
Giolai, Michael;
Krautgasser, Claudia;
Remedi, Maria S.;
Nichols, Colin G.;
Meyer, Dirk

Publication type:

Article

A Unique High-Output Cardiac Hypertrophy Phenotype Arising From Low Systemic Vascular Resistance in Cantu Syndrome.

Published in:

Journal of the American Heart Association, 2022, v. 11, n. 24, p. 1, doi. 10.1161/JAHA.122.027363

By:

Singh, Gautam K.;
McClenaghan, Conor;
Aggarwal, Manish;
Hongjie Gu;
Remedi, Maria S.;
Grange, Dorothy K.;
Nichols, Colin G.

Publication type:

Article

Sulfonylurea challenge test in subjects diagnosed with type 1 diabetes mellitus.

Published in:

Pediatric Diabetes, 2017, v. 18, n. 8, p. 777, doi. 10.1111/pedi.12489

By:

Remedi, Maria S.;
Thomas, Mareen;
Nichols, Colin G.;
Marshall, Bess A.

Publication type:

Article

The role of membrane excitability in pancreatic β-cell glucotoxicity.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-43452-8

By:

Shyr, Zeenat A.;
Wang, Zhiyu;
York, Nathaniel W.;
Nichols, Colin G.;
Remedi, Maria S.

Publication type:

Article

Block of Kv1.7 potassium currents increases glucose-stimulated insulin secretion.

Published in:

EMBO Molecular Medicine, 2012, v. 4, n. 5, p. 424, doi. 10.1002/emmm.201200218

By:

Finol-Urdaneta, Rocio K.;
Remedi, Maria S.;
Raasch, Walter;
Becker, Stefan;
Clark, Robert B.;
Strüver, Nina;
Pavlov, Evgeny;
Nichols, Colin G.;
French, Robert J.;
Terlau, Heinrich

Publication type:

Article

KATP channelopathies in the pancreas.

Published in:

Pflügers Archiv: European Journal of Physiology, 2010, v. 460, n. 2, p. 307, doi. 10.1007/s00424-009-0756-x

By:

Remedi, Maria S.;
Koster, Joseph C.

Publication type:

Article

Kir6.1‐dependent KATP channels in lymphatic smooth muscle and vessel dysfunction in mice with Kir6.1 gain‐of‐function.

Published in:

Journal of Physiology, 2020, v. 598, n. 15, p. 3107, doi. 10.1113/JP279612

By:

Davis, Michael J.;
Kim, Hae Jin;
Zawieja, Scott D.;
Castorena‐Gonzalez, Jorge A.;
Gui, Peichun;
Li, Min;
Saunders, Brian T.;
Zinselmeyer, Bernd H.;
Randolph, Gwendalyn J.;
Remedi, Maria S.;
Nichols, Colin G.

Publication type:

Article

Intermittent fasting preserves beta-cell mass in obesity-induced diabetes via the autophagy-lysosome pathway.

Published in:

Autophagy, 2017, v. 13, n. 11, p. 1952, doi. 10.1080/15548627.2017.1368596

By:

Liu, Haiyan;
Javaheri, Ali;
Godar, Rebecca J.;
Murphy, John;
Ma, Xiucui;
Rohatgi, Nidhi;
Mahadevan, Jana;
Hyrc, Krzysztof;
Saftig, Paul;
Marshall, Connie;
McDaniel, Michael L.;
Remedi, Maria S.;
Razani, Babak;
Urano, Fumihiko;
Diwan, Abhinav

Publication type:

Article

Loss of β-cell identity and dedifferentiation, not an irreversible process?

Published in:

Frontiers in Endocrinology, 2024, p. 1, doi. 10.3389/fendo.2024.1414447

By:

Patel, Sumit;
Remedi, Maria S.

Publication type:

Article

Gain‐of‐Function Lrp5 Mutation Improves Bone Mass and Strength and Delays Hyperglycemia in a Mouse Model of Insulin‐Deficient Diabetes.

Published in:

Journal of Bone & Mineral Research, 2021, v. 36, n. 7, p. 1403, doi. 10.1002/jbmr.4303

By:

Leanza, Giulia;
Fontana, Francesca;
Lee, Seung‐Yon;
Remedi, Maria S.;
Schott, Céline;
Ferron, Mathieu;
Hamilton‐Hall, Malcolm;
Alippe, Yael;
Strollo, Rocky;
Napoli, Nicola;
Civitelli, Roberto

Publication type:

Article

Glycogen Synthase Kinase-3 and Mammalian Target of Rapamycin Pathways Contribute to DNA Synthesis, Cell Cycle Progression, and Proliferation in Human Islets.

Published in:

Diabetes, 2009, v. 58, n. 3, p. 663, doi. 10.2337/db07-1208

By:

Liu, Hui;
Remedi, Maria S.;
Pappan, Kirk L.;
Kwon, Guim;
Rohatgi, Nidhi;
Marshall, Connie A.;
McDaniel, Michael L.

Publication type:

Article

Glycogen Synthase Kinase-3 (GSK-3) Signaling to Mammalian Target of Rapamycin (mTOR) Regulates DNA Synthesis and Cell Cycle Progression in Rodent and Human Islets.

Published in:

Diabetes, 2007, v. 56, p. A444

By:

Pappan, Kirk L.;
Liu, Hui;
Remedi, Maria S.;
Marshall, Connie A.;
Kwon, Guim;
McDaniel, Michael L.

Publication type:

Article

Expression of ATP-Insensitive KATP Channels in Pancreatic β-Cells Underlies a Spectrum of Diabetic Phenotypes.

Published in:

Diabetes, 2006, v. 55, n. 11, p. 2957, doi. 10.2337/db06-0732

By:

Koster, Joseph C.;
Remedi, Maria S.;
Masia, Ricard;
Patton, Brian;
Tong, Ailing;
Nichols, Colin G.

Publication type:

Article

ATP-sensitive K+ channel signaling in glucokinase-deficient diabetes.

Published in:

2005

By:

Remedi, Maria S.;
Koster, Joseph C.;
Patton, Brian L.;
Nichols, Colin G.

Publication type:

journal article

ATP and sulfonylurea sensitivity of mutant ATP-sensitive K+ channels in neonatal diabetes: implications for pharmacogenomic therapy.

Published in:

2005

By:

Koster JC;
Remedi MS;
Dao C;
Nichols CG;
Koster, Joseph C;
Remedi, Maria S;
Dao, Crystal;
Nichols, Colin G

Publication type:

journal article

ATP and Sulfonylurea Sensitivity of Mutant ATP-Sensitive K+ Channels in Neonatal Diabetes.

Published in:

Diabetes, 2005, v. 54, n. 9, p. 2645, doi. 10.2337/diabetes.54.9.2645

By:

Koster, Joseph C.;
Remedi, Maria S.;
Dao, Crystal;
Nichols, Colin G.

Publication type:

Article

Signaling Elements Involved in the Metabolic Regulation ofmTOR by Nutrients, Incretins, and Growth Factors in Islets.

Published in:

Diabetes, 2004, v. 53, p. S225, doi. 10.2337/diabetes.53.suppl_3.S225

By:

Kwon, Guim;
Marshall, Connie A.;
Pappan, Kirk L.;
Remedi, Maria S.;
McDaniel, Michael L.

Publication type:

Article

Diet-induced glucose intolerance in mice with decreased beta-cell ATP-sensitive K+ channels.

Published in:

2004

By:

Remedi, Maria S.;
Koster, Joseph. C.;
Markova, Kamelia;
Seino, Susumu;
Miki, Takashi;
Patton, Brian L.;
McDaniel, Michael L.;
Nichols, Colin G.

Publication type:

journal article

HIV protease inhibitors acutely impair glucose-stimulated insulin release.

Published in:

2003

By:

Koster, Joseph C.;
Remedi, Maria S.;
Qiu, Haijun;
Nichols, Colin G.;
Hruz, Paul W.

Publication type:

journal article

Cantú syndrome: Findings from 74 patients in the International Cantú Syndrome Registry.

Published in:

American Journal of Medical Genetics. Part C: Seminars in Medical Genetics, 2019, v. 181, n. 4, p. 658, doi. 10.1002/ajmg.c.31753

By:

Grange, Dorothy K.;
Roessler, Helen I.;
McClenaghan, Conor;
Duran, Karen;
Shields, Kathleen;
Remedi, Maria S.;
Knoers, Nine V. A. M.;
Lee, Jin‐Moo;
Kirk, Edwin P.;
Scurr, Ingrid;
Smithson, Sarah F.;
Singh, Gautam K.;
Haelst, Mieke M.;
Nichols, Colin G.;
Haaften, Gijs

Publication type:

Article

Beta‐cell excitability and excitability‐driven diabetes in adult Zebrafish islets.

Published in:

Physiological Reports, 2019, v. 7, n. 11, p. N.PAG, doi. 10.14814/phy2.14101

By:

Emfinger, Christopher H.;
Lőrincz, Réka;
Wang, Yixi;
York, Nathaniel W.;
Singareddy, Soma S.;
Ikle, Jennifer M.;
Tryon, Robert C.;
McClenaghan, Conor;
Shyr, Zeenat A.;
Huang, Yan;
Reissaus, Christopher A.;
Meyer, Dirk;
Piston, David W.;
Hyrc, Krzysztof;
Remedi, Maria S.;
Nichols, Colin G.

Publication type:

Article

Loss of β-Cell KATP Reduces Ca2+ Sensitivity of Insulin Secretion and Trpm5 Expression.

Published in:

Diabetes, 2025, v. 74, n. 3, p. 376, doi. 10.2337/db24-0650

By:

York, Nathaniel W.;
Yan, Zihan;
Osipovich, Anna B.;
Tate, Abbie;
Patel, Sumit;
Piston, David W.;
Magnuson, Mark A.;
Remedi, Maria S.;
Nichols, Colin G.

Publication type:

Article

Glucokinase Inhibition: A Novel Treatment for Diabetes?

Published in:

Diabetes, 2023, v. 72, n. 2, p. 170, doi. 10.2337/db22-0731

By:

Remedi, Maria S.;
Nichols, Colin G.

Publication type:

Article

Genetic Reduction of Glucose Metabolism Preserves Functional β-Cell Mass in KATP-Induced Neonatal Diabetes.

Published in:

2022

By:

Yan, Zihan;
Fortunato, Manuela;
Shyr, Zeenat A.;
Clark, Amy L.;
Fuess, Matt;
Nichols, Colin G.;
Remedi, Maria S.

Publication type:

journal article

ATP-Sensitive Potassium Channels in Hyperinsulinism and Type 2 Diabetes: Inconvenient Paradox or New Paradigm?

Published in:

2022

By:

Nichols, Colin G.;
York, Nathaniel W.;
Remedi, Maria S.

Publication type:

journal article

43-OR: Islet Autophagic Flux Is Impaired Prior to the Onset of Type 1 Diabetes.

Published in:

Diabetes, 2021, v. 70, p. N.PAG, doi. 10.2337/db21-43-OR

By:

CLARK, AMY L.;
YAN, ZIHAN;
REMEDI, MARIA S.;
DIWAN, ABHINAV

Publication type:

Article

1789-P: Inactivation of Acyl-Protein Thioesterase 1, a Major Mediator of Palmitoylation Cycling, Promotes Insulin Secretion and ß-Cell Failure.

Published in:

Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-1789-P

By:

DONG, GUIFANG;
WEI, XIAOCHAO;
YIN, LI;
FENG, CHU;
ADAK, SANGEETA;
SHYR, ZEENAT A.;
ZHANG, QIANG;
MORIKAWA, SHUNTARO;
ASADA, RIE;
URANO, FUMIHIKO;
REMEDI, MARIA S.;
SEMENKOVICH, CLAY F.

Publication type:

Article

86-OR: High-Fat Diet Prevents Autoimmune Diabetes in NOD Mice.

Published in:

Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-86-OR

By:

CLARK, AMY L.;
YAN, ZIHAN;
CHEN, SOPHIA X.;
FUESS, MATT;
MCGINN, GABRIELLE;
REMEDI, MARIA S.

Publication type:

Article

334-LB: Dapagliflozin, a SGLT2 Inhibitor, Therapy Improves ß-Cell Function in Neonatal Diabetes by Reducing Oxidative and ER Stress, and Loss of ß-Cell Identity.

Published in:

Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-334-LB

By:

YAN, ZIHAN;
SHYR, ZEENAT A.;
REMEDI, MARIA S.

Publication type:

Article

The Mechanism of High-Output Cardiac Hypertrophy Arising From Potassium Channel Gain-of-Function in Cantú Syndrome.

Published in:

Function, 2020, v. 1, n. 1, p. 1, doi. 10.1093/function/zqaa004

By:

McClenaghan, Conor;
Yan Huang;
Matkovich, Scot J.;
Kovacs, Attila;
Weinheimer, Carla J.;
Perez, Ron;
Broekelmann, Thomas J.;
Harter, Theresa M.;
Jin-Moo Lee;
Remedi, Maria S.;
Nichols, Colin G.

Publication type:

Article

Genome-edited zebrafish model of ABCC8 loss-of-function disease.

Published in:

Islets, 2022, v. 14, n. 1, p. 200, doi. 10.1080/19382014.2022.2149206

By:

Ikle, Jennifer M.;
Tryon, Robert C.;
Singareddy, Soma S.;
York, Nathaniel W.;
Remedi, Maria S.;
Nichols, Colin G.

Publication type:

Article

Works matching AU Remedi, Maria S.

Critical Role of Gap Junction Coupled KATP Channel Activity for Regulated Insulin Secretion.

High‐fat diet prevents the development of autoimmune diabetes in NOD mice.

High‐fat‐diet‐induced remission of diabetes in a subset of K<sub>ATP</sub>‐GOF insulin‐secretory‐deficient mice.

SGLT2 inhibitors therapy protects glucotoxicity-induced β-cell failure in a mouse model of human K<sub>ATP</sub>-induced diabetes through mitigation of oxidative and ER stress.

Preferential Gq signaling in diabetes: an electrical switch in incretin action and in diabetes progression?

Glibenclamide reverses cardiovascular abnormalities of Cantu syndrome driven by KATP channel overactivity.

Rpl13a small nucleolar RNAs regulate systemic glucose metabolism.

Remission of Severe Neonatal Diabetes With Very Early Sulfonylurea Treatment.

In vivo monitoring of intracellular Ca<sup>2+</sup> dynamics in the pancreatic β-cells of zebrafish embryos.

A Unique High-Output Cardiac Hypertrophy Phenotype Arising From Low Systemic Vascular Resistance in Cantu Syndrome.

Sulfonylurea challenge test in subjects diagnosed with type 1 diabetes mellitus.

The role of membrane excitability in pancreatic β-cell glucotoxicity.

Block of K<sub>v</sub>1.7 potassium currents increases glucose-stimulated insulin secretion.

K<sub>ATP</sub> channelopathies in the pancreas.

Kir6.1‐dependent K<sub>ATP</sub> channels in lymphatic smooth muscle and vessel dysfunction in mice with Kir6.1 gain‐of‐function.

Intermittent fasting preserves beta-cell mass in obesity-induced diabetes via the autophagy-lysosome pathway.

Loss of β-cell identity and dedifferentiation, not an irreversible process?

Gain‐of‐Function Lrp5 Mutation Improves Bone Mass and Strength and Delays Hyperglycemia in a Mouse Model of Insulin‐Deficient Diabetes.

Glycogen Synthase Kinase-3 and Mammalian Target of Rapamycin Pathways Contribute to DNA Synthesis, Cell Cycle Progression, and Proliferation in Human Islets.

Glycogen Synthase Kinase-3 (GSK-3) Signaling to Mammalian Target of Rapamycin (mTOR) Regulates DNA Synthesis and Cell Cycle Progression in Rodent and Human Islets.

Expression of ATP-Insensitive K<sub>ATP</sub> Channels in Pancreatic β-Cells Underlies a Spectrum of Diabetic Phenotypes.

ATP-sensitive K+ channel signaling in glucokinase-deficient diabetes.

ATP and sulfonylurea sensitivity of mutant ATP-sensitive K+ channels in neonatal diabetes: implications for pharmacogenomic therapy.

ATP and Sulfonylurea Sensitivity of Mutant ATP-Sensitive K<sup>+</sup> Channels in Neonatal Diabetes.

Signaling Elements Involved in the Metabolic Regulation ofmTOR by Nutrients, Incretins, and Growth Factors in Islets.

Diet-induced glucose intolerance in mice with decreased beta-cell ATP-sensitive K+ channels.

HIV protease inhibitors acutely impair glucose-stimulated insulin release.

Cantú syndrome: Findings from 74 patients in the International Cantú Syndrome Registry.

Beta‐cell excitability and excitability‐driven diabetes in adult Zebrafish islets.

Loss of β-Cell K<sub>ATP</sub> Reduces Ca<sup>2+</sup> Sensitivity of Insulin Secretion and Trpm5 Expression.

Glucokinase Inhibition: A Novel Treatment for Diabetes?

Genetic Reduction of Glucose Metabolism Preserves Functional β-Cell Mass in KATP-Induced Neonatal Diabetes.

ATP-Sensitive Potassium Channels in Hyperinsulinism and Type 2 Diabetes: Inconvenient Paradox or New Paradigm?

43-OR: Islet Autophagic Flux Is Impaired Prior to the Onset of Type 1 Diabetes.

1789-P: Inactivation of Acyl-Protein Thioesterase 1, a Major Mediator of Palmitoylation Cycling, Promotes Insulin Secretion and ß-Cell Failure.

86-OR: High-Fat Diet Prevents Autoimmune Diabetes in NOD Mice.

334-LB: Dapagliflozin, a SGLT2 Inhibitor, Therapy Improves ß-Cell Function in Neonatal Diabetes by Reducing Oxidative and ER Stress, and Loss of ß-Cell Identity.

The Mechanism of High-Output Cardiac Hypertrophy Arising From Potassium Channel Gain-of-Function in Cantú Syndrome.

Genome-edited zebrafish model of ABCC8 loss-of-function disease.