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Heterologe Expression, Biosynthese und ökologische Funktion des selektiven Gq‐Signaltransduktionsinhibitors FR900359.
Published in:
Angewandte Chemie, 2018, v. 130, n. 3, p. 844, doi. 10.1002/ange.201707996
By:
- Crüsemann, Max;
- Reher, Raphael;
- Schamari, Isabella;
- Brachmann, Alexander O.;
- Ohbayashi, Tsubasa;
- Kuschak, Markus;
- Malfacini, Davide;
- Seidinger, Alexander;
- Pinto‐Carbó, Marta;
- Richarz, René;
- Reuter, Tatjana;
- Kehraus, Stefan;
- Hallab, Asis;
- Attwood, Misty;
- Schiöth, Helgi B.;
- Mergaert, Peter;
- Kikuchi, Yoshitomo;
- Schäberle, Till F.;
- Kostenis, Evi;
- Wenzel, Daniela
Publication type:
Article
Native metabolomics identifies the rivulariapeptolide family of protease inhibitors.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32016-6
By:
- Reher, Raphael;
- Aron, Allegra T.;
- Fajtová, Pavla;
- Stincone, Paolo;
- Wagner, Berenike;
- Pérez-Lorente, Alicia I.;
- Liu, Chenxi;
- Shalom, Ido Y. Ben;
- Bittremieux, Wout;
- Wang, Mingxun;
- Jeong, Kyowon;
- Matos-Hernandez, Marie L.;
- Alexander, Kelsey L.;
- Caro-Diaz, Eduardo J.;
- Naman, C. Benjamin;
- Scanlan, J. H. William;
- Hochban, Phil M. M.;
- Diederich, Wibke E.;
- Molina-Santiago, Carlos;
- Romero, Diego
Publication type:
Article
Heterologous Expression, Biosynthetic Studies, and Ecological Function of the Selective Gq‐Signaling Inhibitor FR900359.
Published in:
Angewandte Chemie International Edition, 2018, v. 57, n. 3, p. 836, doi. 10.1002/anie.201707996
By:
- Crüsemann, Max;
- Reher, Raphael;
- Schamari, Isabella;
- Brachmann, Alexander O.;
- Ohbayashi, Tsubasa;
- Kuschak, Markus;
- Malfacini, Davide;
- Seidinger, Alexander;
- Pinto‐Carbó, Marta;
- Richarz, René;
- Reuter, Tatjana;
- Kehraus, Stefan;
- Hallab, Asis;
- Attwood, Misty;
- Schiöth, Helgi B.;
- Mergaert, Peter;
- Kikuchi, Yoshitomo;
- Schäberle, Till F.;
- Kostenis, Evi;
- Wenzel, Daniela
Publication type:
Article
Deciphering Specificity Determinants for FR900359‐Derived Gqα Inhibitors Based on Computational and Structure–Activity Studies.
Published in:
ChemMedChem, 2018, v. 13, n. 16, p. 1634, doi. 10.1002/cmdc.201800304
By:
- Reher, Raphael;
- Kühl, Toni;
- Annala, Suvi;
- Benkel, Tobias;
- Kaufmann, Desireé;
- Nubbemeyer, Britta;
- Odhiambo, Justin Patrick;
- Heimer, Pascal;
- Bäuml, Charlotte Anneke;
- Kehraus, Stefan;
- Crüsemann, Max;
- Kostenis, Evi;
- Tietze, Daniel;
- König, Gabriele M.;
- Imhof, Diana
Publication type:
Article
Front Cover: Deciphering Specificity Determinants for FR900359‐Derived Gqα Inhibitors Based on Computational and Structure–Activity Studies (ChemMedChem 16/2018).
Published in:
ChemMedChem, 2018, v. 13, n. 16, p. 1617, doi. 10.1002/cmdc.201800521
By:
- Reher, Raphael;
- Kühl, Toni;
- Annala, Suvi;
- Benkel, Tobias;
- Kaufmann, Desireé;
- Nubbemeyer, Britta;
- Odhiambo, Justin Patrick;
- Heimer, Pascal;
- Bäuml, Charlotte Anneke;
- Kehraus, Stefan;
- Crüsemann, Max;
- Kostenis, Evi;
- Tietze, Daniel;
- König, Gabriele M.;
- Imhof, Diana
Publication type:
Article
Systematic classification of unknown metabolites using high-resolution fragmentation mass spectra.
Published in:
Nature Biotechnology, 2021, v. 39, n. 4, p. 462, doi. 10.1038/s41587-020-0740-8
By:
- Dührkop, Kai;
- Nothias, Louis-Félix;
- Fleischauer, Markus;
- Reher, Raphael;
- Ludwig, Marcus;
- Hoffmann, Martin A.;
- Petras, Daniel;
- Gerwick, William H.;
- Rousu, Juho;
- Dorrestein, Pieter C.;
- Böcker, Sebastian
Publication type:
Article
A Multi-Omics Characterization of the Natural Product Potential of Tropical Filamentous Marine Cyanobacteria.
Published in:
Marine Drugs, 2021, v. 19, n. 1, p. 20, doi. 10.3390/md19010020
By:
- Leão, Tiago;
- Wang, Mingxun;
- Moss, Nathan;
- da Silva, Ricardo;
- Sanders, Jon;
- Nurk, Sergey;
- Gurevich, Alexey;
- Humphrey, Gregory;
- Reher, Raphael;
- Zhu, Qiyun;
- Belda-Ferre, Pedro;
- Glukhov, Evgenia;
- Whitner, Syrena;
- Alexander, Kelsey L.;
- Rex, Robert;
- Pevzner, Pavel;
- Dorrestein, Pieter C.;
- Knight, Rob;
- Bandeira, Nuno;
- Gerwick, William H.
Publication type:
Article
Decoding the molecular interplay in the central dogma: An overview of mass spectrometry‐based methods to investigate protein‐metabolite interactions.
Published in:
Proteomics, 2024, v. 24, n. 12/13, p. 1, doi. 10.1002/pmic.202200533
By:
- Stincone, Paolo;
- Naimi, Amira;
- Saviola, Anthony J.;
- Reher, Raphael;
- Petras, Daniel
Publication type:
Article
The genome analysis of C andidatus Burkholderia crenata reveals that secondary metabolism may be a key function of the A rdisia crenata leaf nodule symbiosis.
Published in:
Environmental Microbiology, 2016, v. 18, n. 8, p. 2507, doi. 10.1111/1462-2920.13184
By:
- Carlier, Aurelien;
- Fehr, Linda;
- Pinto ‐ Carbó, Marta;
- Schäberle, Till;
- Reher, Raphael;
- Dessein, Steven;
- König, Gabriele;
- Eberl, Leo
Publication type:
Article
Cell-permeable high-affinity tracers for Gq proteins provide structural insights, reveal distinct binding kinetics and identify small molecule inhibitors.
Published in:
2020
By:
- Kuschak, Markus;
- Namasivayam, Vigneshwaran;
- Rafehi, Muhammad;
- Voss, Jan H.;
- Garg, Jaspal;
- Schlegel, Jonathan G.;
- Abdelrahman, Aliaa;
- Kehraus, Stefan;
- Reher, Raphael;
- Küppers, Jim;
- Sylvester, Katharina;
- Hinz, Sonja;
- Matthey, Michaela;
- Wenzel, Daniela;
- Fleischmann, Bernd K.;
- Pfeifer, Alexander;
- Inoue, Asuka;
- Gütschow, Michael;
- König, Gabriele M.;
- Müller, Christa E.
Publication type:
journal article
Lack of beta-arrestin signaling in the absence of active G proteins.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-017-02661-3
By:
- Grundmann, Manuel;
- Merten, Nicole;
- Malfacini, Davide;
- Asuka Inoue;
- Preis, Philip;
- Simon, Katharina;
- Rüttiger, Nelly;
- Ziegler, Nicole;
- Benkel, Tobias;
- Schmitt, Nina Katharina;
- Ishida, Satoru;
- Müller, Ines;
- Reher, Raphael;
- Kawakami, Kouki;
- Inoue, Ayumi;
- Rick, Ulrike;
- Kühl, Toni;
- Imhof, Diana;
- Aoki, Junken;
- König, Gabriele M.
Publication type:
Article
DeepSAT: Learning Molecular Structures from Nuclear Magnetic Resonance Data.
Published in:
Journal of Cheminformatics, 2023, v. 15, n. 1, p. 1, doi. 10.1186/s13321-023-00738-4
By:
- Kim, Hyun Woo;
- Zhang, Chen;
- Reher, Raphael;
- Wang, Mingxun;
- Alexander, Kelsey L.;
- Nothias, Louis-Félix;
- Han, Yoo Kyong;
- Shin, Hyeji;
- Lee, Ki Yong;
- Lee, Kyu Hyeong;
- Kim, Myeong Ji;
- Dorrestein, Pieter C.;
- Gerwick, William H.;
- Cottrell, Garrison W.
Publication type:
Article
DeepSAT: Learning Molecular Structures from Nuclear Magnetic Resonance Data.
Published in:
Journal of Cheminformatics, 2023, v. 15, n. 1, p. 1, doi. 10.1186/s13321-023-00738-4
By:
- Kim, Hyun Woo;
- Zhang, Chen;
- Reher, Raphael;
- Wang, Mingxun;
- Alexander, Kelsey L.;
- Nothias, Louis-Félix;
- Han, Yoo Kyong;
- Shin, Hyeji;
- Lee, Ki Yong;
- Lee, Kyu Hyeong;
- Kim, Myeong Ji;
- Dorrestein, Pieter C.;
- Gerwick, William H.;
- Cottrell, Garrison W.
Publication type:
Article

Found: 13

Heterologe Expression, Biosynthese und ökologische Funktion des selektiven Gq‐Signaltransduktionsinhibitors FR900359.

Native metabolomics identifies the rivulariapeptolide family of protease inhibitors.

Heterologous Expression, Biosynthetic Studies, and Ecological Function of the Selective Gq‐Signaling Inhibitor FR900359.

Deciphering Specificity Determinants for FR900359‐Derived G<sub>q</sub>α Inhibitors Based on Computational and Structure–Activity Studies.

Front Cover: Deciphering Specificity Determinants for FR900359‐Derived G<sub>q</sub>α Inhibitors Based on Computational and Structure–Activity Studies (ChemMedChem 16/2018).

Systematic classification of unknown metabolites using high-resolution fragmentation mass spectra.

A Multi-Omics Characterization of the Natural Product Potential of Tropical Filamentous Marine Cyanobacteria.

Decoding the molecular interplay in the central dogma: An overview of mass spectrometry‐based methods to investigate protein‐metabolite interactions.

The genome analysis of C andidatus Burkholderia crenata reveals that secondary metabolism may be a key function of the A rdisia crenata leaf nodule symbiosis.

Cell-permeable high-affinity tracers for G<sub>q</sub> proteins provide structural insights, reveal distinct binding kinetics and identify small molecule inhibitors.

Lack of beta-arrestin signaling in the absence of active G proteins.

DeepSAT: Learning Molecular Structures from Nuclear Magnetic Resonance Data.

DeepSAT: Learning Molecular Structures from Nuclear Magnetic Resonance Data.