Works by Reggio, Patricia H.

Results: 26

An Overview on Medicinal Chemistry of Synthetic and Natural Derivatives of Cannabidiol.

Published in:

Frontiers in Pharmacology, 2017, p. 1, doi. 10.3389/fphar.2017.00422

By:

Morales, Paula;
Reggio, Patricia H.;
Jagerovic, Nadine

Publication type:

Article

Enhanced Functional Activity of the Cannabinoid Type-1 Receptor Mediates Adolescent Behavior.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 41, p. 13975, doi. 10.1523/JNEUROSCI.1937-15.2015

By:

Schneider, Miriam;
Kasanetz, Fernando;
Lynch, Diane L.;
Friemel, Chris M.;
Lassalle, Olivier;
Hurst, Dow P.;
Steindel, Frauke;
Monory, Krisztina;
Schäfer, Carola;
Miederer, Isabelle;
Markus Leweke, F.;
Schreckenberger, Mathias;
Lutz, Beat;
Reggio, Patricia H.;
Manzoni, Olivier J.;
Spanagel, Rainer

Publication type:

Article

Towards A Molecular Understanding of The Cannabinoid Related Orphan Receptor GPR18: A Focus on Its Constitutive Activity.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 9, p. 2300, doi. 10.3390/ijms20092300

By:

Sotudeh, Noori;
Morales, Paula;
Hurst, Dow P.;
Lynch, Diane L.;
Reggio, Patricia H.

Publication type:

Article

Structural Insights into CB1 Receptor Biased Signaling.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 8, p. 1837, doi. 10.3390/ijms20081837

By:

Al-Zoubi, Rufaida;
Morales, Paula;
Reggio, Patricia H.

Publication type:

Article

Cannabinoid CB1 receptor recognition of endocannabinoids via the lipid bilayer: molecular dynamics simulations of CB1 transmembrane helix 6 and anandamide in a phospholipid bilayer.

Published in:

Journal of Computer-Aided Molecular Design, 2006, v. 20, n. 7/8, p. 495, doi. 10.1007/s10822-006-9068-9

By:

Lynch, Diane L.;
Reggio, Patricia H.

Publication type:

Article

Cannabinoid CB1 receptor recognition of endocannabinoids via the lipid bilayer: molecular dynamics simulations of CB1 transmembrane helix 6 and anandamide in a phospholipid bilayer.

Published in:

Journal of Computer-Aided Molecular Design, 2006, v. 20, n. 7/8, p. 495, doi. 10.1007/s10822-006-9068-9

By:

Lynch, Diane L.;
Reggio, Patricia H.

Publication type:

Article

Endocannabinoid tone versus constitutive activity of cannabinoid receptors.

Published in:

2011

By:

Howlett, Allyn C.;
Reggio, Patricia H.;
Childers, Steven R.;
Hampson, Robert E.;
Ulloa, Nadine M.;
Deutsch, Dale G.

Publication type:

journal article

Molecular determinants for binding of methylenedioxytryptamines at 5-HT/LSD receptors.

Published in:

International Journal of Quantum Chemistry, 1981, v. 20, p. 373, doi. 10.1002/qua.560200734

By:

Reggio, Patricia H.;
Weinstein, Harel;
Osman, Roman;
Topiol, Sid

Publication type:

Article

Cannabinoid Ligands Targeting TRP Channels.

Published in:

Frontiers in Molecular Neuroscience, 2019, p. N.PAG, doi. 10.3389/fnmol.2018.00487

By:

Muller, Chanté;
Morales, Paula;
Reggio, Patricia H.

Publication type:

Article

Parameterization of Org27569: An allosteric modulator of the cannabinoid CB1 G protein-coupled receptor.

Published in:

Journal of Computational Chemistry, 2011, v. 32, n. 10, p. 2119, doi. 10.1002/jcc.21794

By:

Iliff, Hadley A.;
Lynch, Diane L.;
Kotsikorou, Evangelia;
Reggio, Patricia H.

Publication type:

Article

Conformational memories with variable bond angles.

Published in:

Journal of Computational Chemistry, 2008, v. 29, n. 5, p. 741, doi. 10.1002/jcc.20822

By:

Whitnell, Robert M.;
Hurst, Dow P.;
Reggio, Patricia H.;
Guarnieri, Frank

Publication type:

Article

Global fold of human cannabinoid type 2 receptor probed by solid-state 13C-, 15N-MAS NMR and molecular dynamics simulations.

Published in:

Proteins, 2014, v. 82, n. 3, p. 452, doi. 10.1002/prot.24411

By:

Kimura, Tomohiro;
Vukoti, Krishna;
Lynch, Diane L.;
Hurst, Dow P.;
Grossfield, Alan;
Pitman, Michael C.;
Reggio, Patricia H.;
Yeliseev, Alexei A.;
Gawrisch, Klaus

Publication type:

Article

Synthesis, Pharmacological Evaluation, and Docking Studies of Novel Pyridazinone‐Based Cannabinoid Receptor Type 2 Ligands.

Published in:

ChemMedChem, 2018, v. 13, n. 11, p. 1102, doi. 10.1002/cmdc.201800152

By:

Ragusa, Giulio;
Bencivenni, Serena;
Morales, Paula;
Callaway, Tyra;
Hurst, Dow P.;
Asproni, Battistina;
Merighi, Stefania;
Loriga, Giovanni;
Pinna, Gerard A.;
Reggio, Patricia H.;
Gessi, Stefania;
Murineddu, Gabriele

Publication type:

Article

Chromenopyrazoles: Non-psychoactive and Selective CB1 Cannabinoid Agonists with Peripheral Antinociceptive Properties.

Published in:

ChemMedChem, 2012, v. 7, n. 3, p. 452, doi. 10.1002/cmdc.201100568

By:

Cumella, Jose;
Hernández-Folgado, Laura;
Girón, Rocio;
Sánchez, Eva;
Morales, Paula;
Hurst, Dow P.;
Gómez-Cañas, Maria;
Gómez-Ruiz, Maria;
Pinto, Diana C. G. A.;
Goya, Pilar;
Reggio, Patricia H.;
Martin, María Isabel;
Fernández-Ruiz, Javier;
Silva, Artur M. S.;
Jagerovic, Nadine

Publication type:

Article

Inside Back Cover: Chromenopyrazoles: Non-psychoactive and Selective CB1 Cannabinoid Agonists with Peripheral Antinociceptive Properties (ChemMedChem 3/2012).

Published in:

ChemMedChem, 2012, v. 7, n. 3, p. 536, doi. 10.1002/cmdc.201290011

By:

Cumella, Jose;
Hernández-Folgado, Laura;
Girón, Rocio;
Sánchez, Eva;
Morales, Paula;
Hurst, Dow P.;
Gómez-Cañas, Maria;
Gómez-Ruiz, Maria;
Pinto, Diana C. G. A.;
Goya, Pilar;
Reggio, Patricia H.;
Martin, María Isabel;
Fernández-Ruiz, Javier;
Silva, Artur M. S.;
Jagerovic, Nadine

Publication type:

Article

Toward the design of cannabinoid CB1 receptor inverse agonists and neutral antagonists.

Published in:

Drug Development Research, 2009, v. 70, n. 8, p. 585, doi. 10.1002/ddr.20337

By:

Reggio, Patricia H.

Publication type:

Article

Pharmacological evaluation of enantiomerically separated positive allosteric modulators of cannabinoid 1 receptor, GAT591 and GAT593.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.919605

By:

Brandt, Asher L.;
Garai, Sumanta;
Zagzoog, Ayat;
Hurst, Dow P.;
Stevenson, Lesley A.;
Pertwee, Roger G.;
Imler, Gregory H.;
Reggio, Patricia H.;
Thakur, Ganesh A.;
Laprairie, Robert B.

Publication type:

Article

The therapeutic potential of orphan GPCRs, GPR35 and GPR55.

Published in:

Frontiers in Pharmacology, 2015, v. 6, p. 1, doi. 10.3389/fphar.2015.00069

By:

Shore, Derek M.;
Reggio, Patricia H.;
Hans Nell, Gerfried Karl;
Ad Sitsen, J. M.

Publication type:

Article

An Analysis of the Putative CBD Binding Site in the Ionotropic Cannabinoid Receptors.

Published in:

Frontiers in Cellular Neuroscience, 2020, v. 14, p. N.PAG, doi. 10.3389/fncel.2020.615811

By:

Muller, Chanté;
Reggio, Patricia H.

Publication type:

Article

Towards a better understanding of the cannabinoid-related orphan receptors GPR3, GPR6, and GPR12.

Published in:

Drug Metabolism Reviews, 2018, v. 50, n. 1, p. 74, doi. 10.1080/03602532.2018.1428616

By:

Morales, Paula;
Isawi, Israa;
Reggio, Patricia H.

Publication type:

Article

A search for properties which produce discrimination between cannabinoid psychoactivity and analgesic activity.

Published in:

International Journal of Quantum Chemistry, 1992, v. 44, n. 2, p. 165, doi. 10.1002/qua.560440207

By:

Reggio, Patricia H.

Publication type:

Article

Computational studies of the 3-Dimensional structure of cyclopenta polycyclic aromatic hydrocarbons containing a gulf region.

Published in:

International Journal of Quantum Chemistry, 1992, v. 41, n. 3, p. 497, doi. 10.1002/qua.560410312

By:

Venegas, Ruben E.;
Reggio, Patricia H.;
Rabinowitz, James R.

Publication type:

Article

GPR6 Structural Insights: Homology Model Construction and Docking Studies.

Published in:

Molecules, 2020, v. 25, n. 3, p. 725, doi. 10.3390/molecules25030725

By:

Isawi, Israa H.;
Morales, Paula;
Sotudeh, Noori;
Hurst, Dow P.;
Lynch, Diane L.;
Reggio, Patricia H.;
Caballero, Julio

Publication type:

Article

Evidence against Cannabinoid Receptor Involvement in Intraocular Pressure Effects of Cannabinoids in Rabbits.

Published in:

Ophthalmic Research, 1997, v. 29, n. 1, p. 1, doi. 10.1159/000267984

By:

Hodges, Linda C.;
Reggio, Patricia H.;
Green, Keith

Publication type:

Article

Agonist alkyl tail interaction with cannabinoid CB1 receptor V6.43/I6.46 groove induces a helix 6 active conformation.

Published in:

International Journal of Quantum Chemistry, 2002, v. 88, n. 1, p. 76, doi. 10.1002/qua.10093

By:

Barnett‐Norris, Judy;
Hurst, Dow P.;
Buehner, Kurt;
Ballesteros, Juan A.;
Guarnieri, Frank;
Reggio, Patricia H.

Publication type:

Article

Mild Generation of o -Quinone Methides. Synthesis of (-)-Hexahydrocannabinol and Dihydrocannabidiol.

Published in:

Synthetic Communications, 2000, v. 30, n. 8, p. 1431, doi. 10.1080/00397910008087171

By:

Wang, Tiansheng;
Burges, Jason P.;
Reggio, Patricia H.;
Seltzman, Herbert H.

Publication type:

Article

Works by Reggio, Patricia H.

An Overview on Medicinal Chemistry of Synthetic and Natural Derivatives of Cannabidiol.

Enhanced Functional Activity of the Cannabinoid Type-1 Receptor Mediates Adolescent Behavior.

Towards A Molecular Understanding of The Cannabinoid Related Orphan Receptor GPR18: A Focus on Its Constitutive Activity.

Structural Insights into CB1 Receptor Biased Signaling.

Cannabinoid CB1 receptor recognition of endocannabinoids via the lipid bilayer: molecular dynamics simulations of CB1 transmembrane helix 6 and anandamide in a phospholipid bilayer.

Cannabinoid CB1 receptor recognition of endocannabinoids via the lipid bilayer: molecular dynamics simulations of CB1 transmembrane helix 6 and anandamide in a phospholipid bilayer.

Endocannabinoid tone versus constitutive activity of cannabinoid receptors.

Molecular determinants for binding of methylenedioxytryptamines at 5-HT/LSD receptors.

Cannabinoid Ligands Targeting TRP Channels.

Parameterization of Org27569: An allosteric modulator of the cannabinoid CB<sub>1</sub> G protein-coupled receptor.

Conformational memories with variable bond angles.

Global fold of human cannabinoid type 2 receptor probed by solid-state <sup>13</sup>C-, <sup>15</sup>N-MAS NMR and molecular dynamics simulations.

Synthesis, Pharmacological Evaluation, and Docking Studies of Novel Pyridazinone‐Based Cannabinoid Receptor Type 2 Ligands.

Chromenopyrazoles: Non-psychoactive and Selective CB<sub>1</sub> Cannabinoid Agonists with Peripheral Antinociceptive Properties.

Inside Back Cover: Chromenopyrazoles: Non-psychoactive and Selective CB<sub>1</sub> Cannabinoid Agonists with Peripheral Antinociceptive Properties (ChemMedChem 3/2012).

Toward the design of cannabinoid CB<sub>1</sub> receptor inverse agonists and neutral antagonists.

Pharmacological evaluation of enantiomerically separated positive allosteric modulators of cannabinoid 1 receptor, GAT591 and GAT593.

The therapeutic potential of orphan GPCRs, GPR35 and GPR55.

An Analysis of the Putative CBD Binding Site in the Ionotropic Cannabinoid Receptors.

Towards a better understanding of the cannabinoid-related orphan receptors GPR3, GPR6, and GPR12.

A search for properties which produce discrimination between cannabinoid psychoactivity and analgesic activity.

Computational studies of the 3-Dimensional structure of cyclopenta polycyclic aromatic hydrocarbons containing a gulf region.

GPR6 Structural Insights: Homology Model Construction and Docking Studies.

Evidence against Cannabinoid Receptor Involvement in Intraocular Pressure Effects of Cannabinoids in Rabbits.

Agonist alkyl tail interaction with cannabinoid CB1 receptor V6.43/I6.46 groove induces a helix 6 active conformation.

Mild Generation of o -Quinone Methides. Synthesis of (-)-Hexahydrocannabinol and Dihydrocannabidiol.